Treatment of Infantile Hemangioma

Infantile hemangioma represents the most common benign tumour arising ininfancy. The natural history of infantile hemangioma is characterized by aproliferative phase during the first few months of life, followed by slower involutionover the years. Evolution of infantile hemangioma has four stages, contain nascent,proliferation, involution, and involuted. Most infantile hemangioma do not requireactive treatment and involute without leaving significant residual. However, someinfantile hemangioma is problematic due to complications such as ulceration,interference with a vital function, or potential disfigurement. The managementapproach for IH contains active non-intervention and active intervention. Thedecision of treatment is based on many factors, including size and location,psychosocial implication, risks and benefits of the proposed therapy. Earlyrecognition of infantile hemangioma is essential for optimal management andpreventing complication.

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Is Timing of Tracheotomy a Factor Influencing the Clinical Course in COVID-19 Patients?

Ear Nose & Throat Journal ◽

10.1177/0145561320974140 ◽

2020 ◽

pp. 014556132097414

Author(s):

Massimo Mesolella

Keyword(s):

Viral Load ◽

Natural History ◽

Clinical Course ◽

Orotracheal Intubation ◽

Early Tracheostomy ◽

Risks And Benefits ◽

Relative Risks ◽

History Of ◽

Complex Decision

The timing of tracheotomy is a complex decision that requires understanding of the relative risks and benefits as compared with prolonging intubation. The role of tracheotomy during the COVID-19 pandemic remains to be determined. There is no evidence that early tracheostomy improves patient’s clinical course and it is not impact on the natural history of these patients. In our opinion, the tracheotomy should be proposed in stable COVID-19 patients after 18th days after orotracheal intubation when the viral load is finished. Only in the case of patients with difficult of intubation do we perform earlier tracheotomies.

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Cerebral Arteriovenous Malformations: Evaluation and Management

The Scientific World JOURNAL ◽

10.1155/2014/649036 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 29

Author(s):

Norman Ajiboye ◽

Nohra Chalouhi ◽

Robert M. Starke ◽

Mario Zanaty ◽

Rodney Bell

Keyword(s):

Natural History ◽

Management Strategy ◽

Review Paper ◽

Imaging Modality ◽

Imaging Techniques ◽

Current Evidence ◽

Advantages And Disadvantages ◽

Risks And Benefits ◽

Frequent Use ◽

History Of

There has been increased detection of incidental AVMs as result of the frequent use of advanced imaging techniques. The natural history of AVM is poorly understood and its management is controversial. This review provides an overview of the epidemiology, pathophysiology, natural history, clinical presentation, diagnosis, and management of AVMs. The authors discussed the imaging techniques available for detecting AVMs with regard to the advantages and disadvantages of each imaging modality. Furthermore, this review paper discusses the factors that must be considered for the most appropriate management strategy (based on the current evidence in the literature) and the risks and benefits of each management option.

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Use of antithrombotic agents in patients with intracerebral cavernous malformations

Journal of Neurosurgery ◽

10.3171/2012.8.jns112050 ◽

2013 ◽

Vol 118 (1) ◽

pp. 43-46 ◽

Cited By ~ 16

Author(s):

Kelly D. Flemming ◽

Michael J. Link ◽

Teresa J. H. Christianson ◽

Robert D. Brown

Keyword(s):

High Risk ◽

Natural History ◽

Antiplatelet Agent ◽

Antithrombotic Agents ◽

Antithrombotic Agent ◽

Cavernous Malformations ◽

Risks And Benefits ◽

History Of ◽

The Mean

Object The goal of this study was to determine the risk of using antithrombotic agents in patients with established intracerebral cavernous malformations (ICMs). Methods From a previously described cohort of 292 patients with radiographically defined ICMs, 40 required an antithrombotic after the ICM was diagnosed. Patients underwent follow-up to determine the incidence of hemorrhage. Results The mean age of these 40 patients was 62.4 years; there were 21 male and 19 female patients. Five (12.5%) of the 40 patients initially presented with hemorrhage and 4 (10%) had multiple ICMs. Of these patients, 32 were placed on an antiplatelet agent alone, 6 on an anticoagulant alone, and 2 were placed on both. In patients necessitating any antithrombotic agent, 1 patient developed a prospective hemorrhage over the 258 person-years of follow-up (prospective hemorrhage rate 0.41% per person-year). Conclusions Antithrombotics likely do not precipitate hemorrhage in patients with known ICMs. However, caution should be exercised in the use of antithrombotics in patients with ICMs at high risk for hemorrhage. The risks and benefits of antithrombotics in each situation should be carefully weighed against the natural history of ICM.

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How is the moral stance related to the intentional stance and group thinking?

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002413 ◽

2020 ◽

Vol 43 ◽

Author(s):

Hannes Rakoczy

Keyword(s):

Natural History ◽

Social Cognitive ◽

Intentional Stance ◽

Cognitive Capacities ◽

Shared Intentionality ◽

History Of ◽

Group Thinking ◽

Moral Stance

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.

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