scholarly journals HENOCH-SCHÖNLEIN PURPURA: A CASE REPORT OF AN EIGHT-YEARS-OLD BOY

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Putu Yunita Primasari
Keyword(s):  
Complete Blood Count ◽  
Small Vessel Vasculitis ◽  
Upper Respiratory Tract ◽  
Henoch Schonlein Purpura ◽  
Keywords Children ◽  
Common Causes ◽  
History Of ◽  
Upper Respiratory ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schönlein Purpura (HSP) is one of the most common causes of small vessel vasculitis mediated by immunoglobulin (Ig) A deposition in children. We present a case of HSP in an eight years old boy with cutaneous, abdomen and joint manifestation of the disease. He had history of upper respiratory tract infection couple weeks before. Physical examination showed erythematous, palpable, purpuric rashes on his both legs and buttocks. Mild bilateral non pitting edema was present over both the legs. Complete blood count (CBC) test revealed thrombocytosis and slightly leukocytosis with neutrophil predominate. The case was treated with oral methylprednisolone for seven days and showed a good outcome. Keywords: Children, Henoch- Schönlein purpura, HSP

scholarly journals A child with Henoch-Schonlein purpura secondary to a COVID-19 infection

2021 ◽  
Vol 14 (1) ◽  
pp. e239910
Author(s):  
Dalal Anwar AlGhoozi ◽  
Haya Mohammed AlKhayyat
Keyword(s):  
Respiratory Tract ◽  
Rna Virus ◽  
Severe Pneumonia ◽  
Small Vessel Vasculitis ◽  
Upper Respiratory Tract ◽  
Henoch Schonlein Purpura ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch-Schonlein purpura (HSP) is a common IgA-mediated small vessel vasculitis of childhood that affects several systems. It is characterised by a tetrad of dermatological, abdominal, joint and renal manifestations. HSP can occur secondary to upper respiratory tract infections, medications, vaccinations and malignancies. COVID-19 is caused by SARS-CoV-2, a single-stranded RNA virus from the Beta-Coronaviridae family, and often presents as a respiratory infection with symptoms ranging from a mild common cold-like illness to severe pneumonia. It has also been reported to exhibit extrapulmonary manifestations, including but not limited to cardiac, thrombotic, hepatocellular and dermatological complications. We report a case of a 4-year-old boy who presented with clinical features of HSP, with detailed history that revealed a recent recovery from a COVID-19 upper respiratory tract infection, indicating a possible correlation between the two.

scholarly journals Clinical profile and pattern of Henoch-Schönlein purpura in children

2015 ◽  
Vol 2 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Ganesh Shah
Keyword(s):  
Renal Involvement ◽  
Clinical Profile ◽  
Upper Respiratory Tract ◽  
Henoch Schonlein Purpura ◽  
Patients Âgés ◽  
Streptolysin O ◽  
Gastrointestinal Manifestation ◽  
Upper Respiratory ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Introduction: This study was done to evaluate clinical profile of Henoch- Schönlein purpura (HSP) in children admitted in Patan Hospital.Methods: The medical records of all the children admitted in children ward with diagnosis of HSP from January 2008 to December 2015 were analysed for clinical presentation, management and outcome.Results: Of 59 patients, 37 (63%) were boys. The patients’ ages ranged from 15 months to 14 years with a mean of 8.3 years. Approximately, two third cases presented during winter and autumn. Upper respiratory tract infection preceded HSP in 37 and anti streptolysin O titer was positive in 6 of the 13 (46%) children tested at presentation. Skin purpura was seen in 59 (100%), arthritis or arthralgia in 48 (81%), gastrointestinal manifestation in 47 (80%) and renal involvement in 16 (27%). Forty-one (69%) patients received corticosteroid therapy. All the children made a full recovery, two with nephritis continued to have hypertension, hematuria and proteinuria. Symptoms occurred in 6 (10%) over a period one month to two years follow up.Conclusions: The HSP in children had seasonal occurrence, skin rash, pain abdomen with mild diseases and recovered well. Journal of Patan Academy of Health Sciences, Vol. 2, No. 1, 2015. page:17-21

scholarly journals Henoch-Schönlein Purpura Following the First Dose of COVID-19 Viral Vector Vaccine: A Case Report

Vaccines ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1078
Author(s):  
Maria Maddalena Sirufo ◽  
Martina Raggiunti ◽  
Lina Maria Magnanimi ◽  
Lia Ginaldi ◽  
Massimo De Martinis
Keyword(s):  
Viral Vector ◽  
Healthy Woman ◽  
Paediatric Rheumatology ◽  
Small Vessel Vasculitis ◽  
Upper Respiratory Tract ◽  
Henoch Schonlein Purpura ◽  
Vector Vaccine ◽  
Tract Infections ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

A 76 year-old female came to our observation one week after the vaccination with ChAdOx1 nCoV-19 AZD1222 for the onset of purpuric rash on her gluteal and legs regions associated with coxalgia and episodes of macrohaematuria. Henoch-Schönlein purpura (HSP) was diagnosed on the basis of the revised criteria developed by the European League Against Rheumatism, the Paediatric Rheumatology International Trials Organization, and the Paediatric Rheumatology European Society (EULAR/PRINTO/PRES). HSP is a common IgA-mediated small vessel vasculitis, typical of childhood, that affects several systems and is characterized by a tetrad of dermatological, abdominal, joint, and renal manifestations. The Etiology of HSP is not completely understood, but it was observed following upper respiratory tract infections, medications, vaccinations, and malignancies. HSP has previously been reported following immunization with various vaccines, mostly within 12 weeks post, suggesting a possible correlation. To our knowledge, this is the first report of the possible association between COVID-19 ChAdOx1 nCoV-19 AZD1222 and the onset of HSP in a previously healthy woman. No similar cases were reported amongst 23.848 participants in the ChAdOx1 nCoV-19 AZD1222 trial.

scholarly journals Henoch-Schonlein Purpura Successfully Treated with Dexamethasone: A Case Report of Six-Year-Old Female

2017 ◽  
Vol 2 (1) ◽  
pp. e000095
Author(s):  
Purushottam Adhikari
Keyword(s):  
Abdominal Pain ◽  
Blood Test ◽  
Occult Blood ◽  
Small Vessel Vasculitis ◽  
Occult Blood Test ◽  
Henoch Schonlein Purpura ◽  
Common Causes ◽  
Schonlein Purpura ◽  
Multiple Episodes ◽  
Henoch Schönlein Purpura

Henoch-Schonlein Purpura (HSP) is one of the most common causes of small vessel vasculitis in children.  A six-year-old female presented with abdominal pain, swelling and rashes over both the legs associated with multiple episodes of vomiting for around ten days. Stool for the occult blood test was positive but there was an absence of hematuria and albuminuria. The case was diagnosed as HSP and treated with dexamethasone for ten days. The patient was finally discharged on the resolution of her symptoms.  Early diagnosis and treatment favor the better outcome in cases without any renal complications. Keywords: Henoch-Schönlein Purpura, Vasculitis, Steroids, Dexamethasone.

Altered mean platelet volume in children with Henoch-Schonlein purpura and its association with disease activity

2017 ◽  
Vol 55 (3) ◽  
pp. 368-372
Author(s):  
Xiang Shi ◽  
Wen-Chao Li ◽  
Li-Jun Mo ◽  
Xiao-Hong Li ◽  
Yu-Zhen Luo ◽  
...  
Keyword(s):  
Acute Phase ◽  
Mean Platelet Volume ◽  
Area Under The Curve ◽  
Small Vessel Vasculitis ◽  
Henoch Schonlein Purpura ◽  
Platelet Volume ◽  
Convalescent Phase ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Background Henoch-Schonlein purpura is a systemic small-vessel vasculitis that occurs mainly in children. A review of the literature has suggested a correlation between mean platelet volume and several inflammatory disorders. However, to the best of our knowledge, any potential correlation between mean platelet volume and Henoch-Schonlein purpura has not been reported in the literature. Therefore, our study aimed to evaluate the role of mean platelet volume concentrations in patients with Henoch-Schonlein purpura. Methods This study included 97 children with Henoch-Schonlein purpura and 120 healthy individuals as controls. Results Mean platelet volume concentrations were found to be significantly lower in Henoch-Schonlein purpura patients compared with healthy controls (8.1 ± 0.86 vs. 9.4 ± 0.81, P < 0.001). Similarly, significant negative correlations were observed between mean platelet volume and neutrophil count, platelet count and erythrocyte sedimentation rate in patients with Henoch-Schonlein purpura (r=−0.327, P = 0.001; r=−0.419, P < 0.001; r=−0.255, P = 0.012). Interestingly, mean platelet volume was significantly lower in the acute phase compared with the convalescent phase of Henoch-Schonlein purpura patients (7.8 ± 0.86 vs. 8.3 ± 0.77, P = 0.002). A cut-off value for mean platelet volume was 7.85 with area under the curve of 0.726 to identify acute phase vs. convalescent phase in patients with Henoch-Schonlein purpura. Mean platelet volume was independently associated with Henoch-Schonlein purpura in logistic regression analysis (odds ratio = 0.114, 95% confidence interval = 0.053–0.243, P < 0.001). Conclusions Our results suggest that mean platelet volume is inversely associated with disease in patients with Henoch-Schonlein purpura, and mean platelet volume may be a useful marker to identify active disease in Henoch-Schonlein purpura patients.

scholarly journals An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura

2012 ◽  
Vol 4 (2) ◽  
pp. 333-335 ◽  
Author(s):  
S K Samanta ◽  
N Mahapatra ◽  
B Aich ◽  
N Sarkar ◽  
A Chatterjee
Keyword(s):  
Unusual Case ◽  
Sinus Thrombosis ◽  
Cortical Blindness ◽  
Small Vessel Vasculitis ◽  
Henoch Schonlein Purpura ◽  
High Grade Fever ◽  
Diffuse Abdominal Pain ◽  
Transient Cortical Blindness ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Introduction: Henoch-Schonlein purpura (HSP) is one of the most common causes of small vessel vasculitis in children, but sometimes may have an atypical presentation. Objective: To report an unusual case of transient cortical blindness in a patient with Henoch-Schonlein purpura. Case: A 3-year-old female child was brought with the complaint of diffuse abdominal pain and hematochezia, which was preceded by high grade fever and cough. Three days later she developed hematuria, hematemesis, melena and hemoptysis along with palpable purpura. Four days later she became irritable and developed a few episodes of generelized tonic clonic seizure, followed by cortical blindness. The CT scan of the brain showed bilateral nonenhancing occipital hypodensity. The magnetic resonance venography showed thrombosis in transverse and sigmoid sinus. She was treated with corticosteroids and her mental status and vision improved. Conclusion: The HSP can cause transient cortical blindness, and recovery is good if therapy is initiated at the appropriate time.DOI: http://dx.doi.org/10.3126/nepjoph.v4i2.6556 Nepal J Ophthalmol 2012; 4 (2): 333-335

scholarly journals Koebner phenomenon in leukocytoclastic vasculitis: A case report and an updated review of the literature

2019 ◽  
Vol 7 ◽  
pp. 2050313X1985035
Author(s):  
Farah Kassam ◽  
Sabrina Nurmohamed ◽  
Richard M Haber
Keyword(s):  
Case Report ◽  
Leukocytoclastic Vasculitis ◽  
Immunoglobulin A ◽  
Small Vessel Vasculitis ◽  
Review Of The Literature ◽  
Henoch Schonlein Purpura ◽  
Koebner Phenomenon ◽  
Vessel Injury ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Leukocytoclastic vasculitis is the most common form of cutaneous vasculitis. It is a neutrophilic small vessel vasculitis resulting from the deposition of circulating immune complexes. Henoch-Schonlein purpura is a systemic type of leukocytoclastic vasculitis, characterized by immunoglobulin A-mediated blood vessel injury. We present a case of Henoch-Schonlein purpura in an adult female manifesting with a vasculitic rash with Koebner phenomenon.

scholarly journals Severe Disfiguring Scalp and Facial Oedema due to Henoch–Schönlein Purpura in a Child

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Visvalingam Arunath ◽  
Arjuna Salinda Athapathu ◽  
Thabitha Jebaseeli Hoole ◽  
Heshan Aruppala ◽  
Asanka Rathnasri ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Urine Analysis ◽  
The Body ◽  
Small Vessel Vasculitis ◽  
Facial Oedema ◽  
Normal Brain ◽  
Henoch Schonlein Purpura ◽  
Facial Swelling ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Henoch–Schönlein purpura is a small vessel vasculitis that usually presents with palpable purpura, arthritis, abdominal pain, and nephritis. Subcutaneous oedema of dependent areas is common; however, oedema in the scalp is extremely rare especially in children older than two years. Here, we report a child with massive disfiguring scalp and facial oedema due to Henoch–Schönlein purpura. An eight-year-old boy presented with characteristic palpable purpuric rash and extensive disfiguring scalp and facial swelling for five days. He complained of blurred vision, vomiting, and severe headache on the day of admission. Examination revealed an ill child with extensive oedema of the face and scalp that was tender on palpation. His blood pressure was above the 99th percentile, and he had exaggerated deep tendon reflexes and extensor plantar responses. All biochemical investigations including renal function tests were normal. Noncontrast CT head showed normal brain, with marked soft tissue swelling of the scalp. Ultrasonography showed soft tissue oedema within and surrounding facial muscles without evidence of neck vessel compression. Urine analysis revealed microscopic haematuria on day 14 of the illness, and immunohistochemical staining of renal biopsy confirmed Henoch–Schönlein purpura nephritis. In conclusion, this case report presents a child with severe, disfiguring scalp and facial oedema due to Henoch–Schönlein purpura. It highlights that severe subcutaneous oedema of Henoch–Schönlein purpura can involve any part of the body not limiting to dependent areas.

scholarly journals A97: Endothelial Function in Children With a History of Henoch-Schonlein Purpura

2014 ◽  
Vol 66 ◽  
pp. S132-S132
Author(s):  
Yonatan butbul Aviel ◽  
Lotem Dafna ◽  
Riva Brik ◽  
Giora Pilar
Keyword(s):  
Endothelial Function ◽  
Henoch Schonlein Purpura ◽  
History Of ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura
Sign in / Sign up

Export Citation Format

Share Document