COMPARATIVE STUDY OF BIOACTIVE GLASS AND FREEZE DRIED BONE ALLOGRAFT IN CLASS II FURCATION DEFECTS

Background: In periodontal therapy, furcation defects are one of the most therapeutically challenging periodontal therapies. Till now various treatment methods have been tried which have shown different success rates. The present study was undertaken to compare the efficacy of bioactive glass (alloplast) with Freeze dried bone allograft (FDBA) in the treatment of Class II furcation defects. Materials and Methods: Twenty patients were selected for the study which had bilateral Class II furcation defects in molars from which ten patients were male and ten patients sere female in the age group of 45-55 years. Various clinical measurements were recorded at three times i.e. at baseline, at one month and at six months post surgery which included the Turesky-Glimore-Glickman modification of the Quigley Hein plaque index, the Loe and silness gingival index, relative clinical attachment level vertical probing depth in the mid-furcation area, and horizontal probing depth in the furcation area. The statistical analysis was done using SPSS version 23.0. Results: In the relative clinical attachment levels, the mean gain in the test and control groups was 2.45 and 1.58 mm, respectively at the end of six months. In the horizontal probing depth values, the mean change in the bioactive glass graft and freeze dried bone allograft was 1.45 and 1.33 mm, respectively. Conclusion: From our study it was concluded that efficacy of Bioactive glass is much better as compared to Freeze dried bone allograft in the treatment of Class II furcation defects. Keywords: Bioactive glass, Freeze dried bone allograft, furcation defects

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Effect of Early Membrane Removal on the Treatment of Mandibular Class II Furcation Defects - A Controlled Clinical Trial with Re-entry after 12 Months

Brazilian Dental Journal ◽

10.1590/0103-6440201302243 ◽

2013 ◽

Vol 24 (4) ◽

pp. 402-409

Author(s):

Alexandre C. Leite ◽

Rafael R. de Oliveira ◽

Arthur B. Novaes Jr. ◽

Patricia A. O'Connell ◽

Marcio F. M. Grisi ◽

...

Keyword(s):

Test Group ◽

Class Ii ◽

Control Group ◽

Controlled Clinical Trial ◽

Hard Tissue ◽

Early Removal ◽

Probing Depth ◽

Furcation Defects ◽

Bone Level ◽

Clinical Measurements

In a previous study in dogs, the early removal of expanded polytetrafluoroethylene (ePTFE) membrane (2 weeks after placement) showed histomorphometric results (of new bone, cementum and periodontal ligament) similar to that obtained with membrane removal at 4 weeks after placement. This study evaluated the influence of early removal of an ePTFE membrane on the treatment of Class II furcation defects. Twelve patients who provided 12 pairs of mandibular furcation defects were recruited for the study. Baseline clinical measurements were recorded: plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), gingival margin position (GMP) and relative clinical attachment level (RCAL). Full flaps were elevated and hard tissue measurements were performed during the surgery: relative vertical (RVBL) and horizontal (RHBL) bone level. The ePTFE membranes were adapted and sutured to their correspondent tooth and removed at 2 weeks in the test group (TGr) and at 4 weeks in the control group (CGr). After 1 year all sites were re-entered, and soft and hard tissue measurements were recorded. There were no statistically significant differences between TGr and CGr for any baseline measurement. After 12 months, there were no statistically significant differences between TGr and CGr in the PD (p=0.74), GMP (p=0.76) and RCAL (p=0.44) values. However, the RHBL resolution was significant for both groups (CGr p=0.01 and TGr p=0.02), without difference between groups (p=0.39). Early removal of membranes did not affect the outcome on the treatment of Class II furcation defects.

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A Comparison of Porous and Non-Porous Teflon Membranes Plus Demineralized Freeze-Dried Bone Allograft in the Treatment of Class II Buccal/Lingual Furcation Defects: A Clinical Reentry Study

Journal of Periodontology ◽

10.1902/jop.2001.72.11.1580 ◽

2001 ◽

Vol 72 (11) ◽

pp. 1580-1587 ◽

Cited By ~ 20

Author(s):

James W. Lamb ◽

Henry Greenwell ◽

Connie Drisko ◽

Robin D. Henderson ◽

James P. Scheetz ◽

...

Keyword(s):

Bone Allograft ◽

Class Ii ◽

Freeze Dried ◽

Furcation Defects

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Platelet-rich fibrin in combination with decalcified freeze-dried bone allograft for the management of mandibular degree II furcation defect: A randomised controlled clinical trial

Singapore Dental Journal ◽

10.1142/s2214607519500032 ◽

2019 ◽

Vol 39 (01) ◽

pp. 33-40 ◽

Cited By ~ 1

Author(s):

Ashish Agarwal ◽

R. G. Shiva Manjunath ◽

Priyamwada Sethi ◽

G. Shiva Shankar

Keyword(s):

Statistical Significance ◽

Periodontal Regeneration ◽

Bone Allograft ◽

Controlled Clinical Trial ◽

Hard Tissue ◽

Platelet Rich Fibrin ◽

Probing Depth ◽

Freeze Dried ◽

Furcation Defects ◽

Intergroup Comparison

Background: Treatment of furcation involvement of molars with periodontal disease remains challenging and unpredictable. Platelet-rich fibrin (PRF) has received the attention of researchers due to its pleiotropic properties essential for periodontal wound healing. The osteoinductive property of demineralized freeze-dried bone allograft (DFDBA) has been successfully used in periodontal regeneration. Aim: The present study aimed to explore the effectiveness of PRF alone and with DFDBA in the treatment of mandibular degree II furcation defects in subjects with chronic periodontitis. Material and Methods: Patients treated were from the Department of Periodontology and Implantology, Institute of Dental Sciences, Bareilly. A total of 60 mandibular molars were treated with either open flap debridement (OFD) alone, [Formula: see text] combination or [Formula: see text] combination. The soft and hard tissue parameters such as vertical probing depth (VPD), vertical clinical attachment level (VCAL), gingival marginal level (GML), horizontal probing depth (HPD), vertical bone fill (VBF), horizontal bone fill (HBF) and furcation width (FW) were determined at baseline and 9 months postoperatively. A paired [Formula: see text]-test was conducted to assess the statistical significance between time period within each group for clinical and radiographic parameters. ANOVA and post-hoc Tukey’s tests were also conducted for intergroup comparison of soft and hard tissue parameters. Statistical significance was set at [Formula: see text]. Results and Discussion: After 9 months, all treatment groups showed significant ([Formula: see text]) improvement in soft and hard tissue parameters, except GML in all the three groups and HBF and FW in the OFD group as compared to baseline. The mean VBF change was highest in the [Formula: see text] group ([Formula: see text]) mm, followed by that in the [Formula: see text] and OFD groups ([Formula: see text] and [Formula: see text][Formula: see text]mm, respectively). Conclusions: It was shown that both [Formula: see text] and [Formula: see text] combinations were significantly advantageous for the management of mandibular degree II furcation defects. However, the [Formula: see text] combination has significantly greater benefits than [Formula: see text] combination in terms of VBF.

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Volumetric changes in edentulous alveolar ridge sites utilizing guided bone regeneration and a custom titanium ridge augmentation matrix (CTRAM): a case series study

International Journal of Implant Dentistry ◽

10.1186/s40729-020-00269-9 ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Craig E. Hofferber ◽

J. Cameron Beck ◽

Peter C. Liacouras ◽

Jeffrey R. Wessel ◽

Thu P. Getka

Keyword(s):

Case Series ◽

Bone Allograft ◽

Volumetric Analysis ◽

Collagen Membrane ◽

Ridge Augmentation ◽

Implant Placement ◽

Case Series Study ◽

Freeze Dried ◽

Clinical Measurements ◽

Bone Gain

Abstract Background The purpose of this study was to evaluate the volumetric changes in partially edentulous alveolar ridges augmented with customized titanium ridge augmentation matrices (CTRAM), freeze-dried bone allograft, and a resorbable collagen membrane. Methods A pre-surgical cone beam computed tomography (CBCT) scan was obtained for CTRAM design/fabrication and to evaluate pre-surgical ridge dimensions. Ridge augmentation surgery using CTRAM, freeze-dried bone allograft, and a resorbable collagen membrane was performed at each deficient site. Clinical measurements of the area of augmentation were made at the time of CTRAM placement and re-entry, and a 2nd CBCT scan 7 months after graft placement was used for volumetric analysis. Locations of each CTRAM in situ were also compared to their planned positions. Re-entry surgery and implant placement was performed 8 months after CTRAM placement. Results Nine subjects were treated with CTRAM and freeze-dried bone allograft. Four out of the nine patients enrolled (44.4%) experienced premature CTRAM exposure during healing, and in two of these cases, CTRAM were removed early. Early exposure did not result in total graft failure in any case. Mean volumetric bone gain was 85.5 ± 30.9% of planned augmentation volume (61.3 ± 33.6% in subjects with premature CTRAM exposure vs. 104.9% for subjects without premature exposure, p = 0.03). Mean horizontal augmentation (measured clinically) was 3.02 mm, and vertical augmentation 2.86 mm. Mean surgical positional deviation of CTRAM from the planned location was 1.09 mm. Conclusion The use of CTRAM in conjunction with bone graft and a collagen membrane resulted in vertical and horizontal bone gain suitable for implant placement.

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Alveolar Ridge Preservation After Tooth Extraction with DFDBA and Platelet Concentrates: A Radiographic Retrospective Study

The Open Dentistry Journal ◽

10.2174/1874210601711010099 ◽

2017 ◽

Vol 11 (1) ◽

pp. 99-108 ◽

Cited By ~ 2

Author(s):

Behrang Baniasadi ◽

Laurence Evrard

Keyword(s):

Bone Loss ◽

Tooth Extraction ◽

Alveolar Bone ◽

Bone Allograft ◽

Ridge Preservation ◽

Platelet Concentrates ◽

Freeze Dried ◽

Significant Difference ◽

Removable Prosthesis ◽

The Mean

Objectives: The purpose of this study was to evaluate vertical alveolar bone loss 3 months after tooth extraction when a technique of ridge preservation was applied using a particulate demineralized freeze-dried bone allograft 300 - 500 µm associated with platelet concentrates (platelet-rich-fibrin) in the form of gel and membranes. Material and Methods: A retrospective radiological clinical study was conducted on 56 patients for whom 95 extractions had been performed immediately followed by alveolar filling. Among the patients, 17 were smokers and 16 were provided with an immediate removable temporary prosthesis after extractions. Vertical bone loss was measured radiologically by panoramic X-ray before extractions and by a computed tomography scan 3 months after, at the level of mid-buccal bone wall, by two independent observers. For statistical analysis, Student’s t-test was performed to compare the mean bone loss between mono- and pluri-radicular teeth and to compare the mean bone loss between tobacco users versus non users and finally to compare the mean bone loss between individuals that had provisional removable prosthesis and those that had not. Results: Three months after tooth extraction, the mean of vertical loss of the mid-buccal bone wall was 0.72 (SD 0.71) mm (5.53% SD 5.19). No significant difference between bone loss at mono-radicular and pluri-radicular teeth (P = 0.982) was observed. There was no significant correlation between tobacco habits and bone loss (P = 0.2), nor between provisional removable prosthesis and bone loss (P = 0.786). Conclusion: These results indicate a good potential for the technique using Demineralized Freeze-Dried Bone Allograft 300 - 500 µm and platelet concentrates in alveolar bone preservation.

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Treatment of a Developmental Groove and Supernumerary Root Using Guided Tissue Regeneration Technique

Case Reports in Dentistry ◽

10.1155/2016/2738569 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5

Author(s):

Zahra Alizadeh Tabari ◽

Hamed Homayouni ◽

Tahere Pourseyediyan ◽

Armita Arvin ◽

Derrick Eiland ◽

...

Keyword(s):

Tissue Regeneration ◽

Root Canal ◽

Combined Treatment ◽

Bone Allograft ◽

Guided Tissue Regeneration ◽

Maxillary Incisor ◽

Treatment Procedure ◽

Root Canal Therapy ◽

Probing Depth ◽

Freeze Dried

Introduction. The radicular groove is a developmental groove which is usually found on the palatal or lateral aspects of the maxillary incisor teeth. The present case is a maxillary lateral incisor with a small second root and a deep radicular groove. The developmental groove caused a combined periodontal-endodontic lesion. Methods. Case was managed using a combined treatment procedure involving nonsurgical root canal therapy and surgical periodontal treatment. After completion of root canal treatment, guided tissue regeneration (GTR) was carried out using decalcified freeze dried bone allograft (DFDBA) and a bioabsorbable collagenous membrane. Tooth also was splinted for two months. Results. After 12 months the tooth was asymptomatic. The periapical radiolucency disappeared and probing depth did not exceed 3 mm. Conclusion. Combined treatment procedure involving nonsurgical root canal therapy and surgical periodontal regenerative treatment can be a predictable technique in treating combined endodontic-periodontal lesions caused by radicular groove.

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