CORRELATION OF CYCLICAL CHANGES IN ENDOMETRIUM AND UTERINE BLOOD FLOW WITH OVULATION, AND TO PREDICT THE APPROXIMATE TIME OF OVULATION

Background & Method: The study was carried out in the Department of Radio diagnosis, Index Medical College, Hospital & Research Centre, Indore with an aim to correlate of cyclical changes in endometrium and uterine blood flow with ovulation, and to predict the approximate time of ovulation. Result: The study shows maximum numbers of cases (78%) have endometrial thickness more than 7 mm and most of them belongs to fertile group, while 22% cases have endometrial thickness less than 7mm and they all belong to infertile group. The study shows 66% of cases have 5 layered endometrial appearance and almost all of them were fertile and 34% cases have hazy 5 layered or no layering and most of them (14 out of 17) belongs to infertile group. In this study 68% patients have multifocal endometrial blood supply and almost all of them are fertile while 32% patients have absent or sparse endometrial blood flow. Conclusion: The advent of color flow imaging has enabled the detection of neovascularization and change in blood flow in endometrium and myometrium. In the study it was noted that 5 layered endometrium was present in almost all fertile cases while in infertile cases endometrium was single layer or hazy 5 layered, so it can be postulated that distinct 5 layered endometrium is associated with fruitful pregnancy outcome. It was also noted frequently in the study that endometrium thickness less than 7mm was commonly seen in infertile cases while patients having more than 7mm thick endometrium were from fertile group, so it can be postulated that good endometrial thickness provides more chances for fruitful pregnancy outcome. Keywords: Endometrium, Uterine & Ovulation.

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SIGNIFICANCE OF PLACENTAL HISTOPATHOLOGICAL FINDINGS IN PRETERM/TERM BIRTH

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i5.1143 ◽

2020 ◽

Vol 4 (5) ◽

Author(s):

Monika Kushwaha ◽

Sanjeev Narang

Keyword(s):

Preterm Birth ◽

Comparative Study ◽

Pregnancy Outcome ◽

Neonatal Morbidity ◽

Research Centre ◽

College Hospital ◽

Cross Sectional ◽

Chorionic Villi ◽

Term Birth ◽

Medical College

Background: This study is cross-sectional, observational and comparative study, at Index Medical College, Hospital & Research Centre, Indore, Madhya Pradesh from July 2017 to July 2019 with sample size 100 placentae. Method: The placenta received was evaluated blinded of maternal pregnancy outcome. The pattern of morphology was evaluated both qualitatively (type of lesion) and quantitatively (number of lesions). Result: In Present study 79% of the deliveries were term deliveries and 21% were preterm deliveries. On placental macroscopy, placenta weight was significantly low among the neonates of preterm deliveries (370.00±60.49) as compared to term deliveries (440.89±55.22). Preterm placenta had higher number of abnormal placental lesion compared to term pregnancies. Conclusion: The uteroplacental insufficiency defined as placental infarct, fibrosis of chorionic villi, thickening of blood vessels, and poor vascularity of chorionic villi. Placental histopathological lesions are strongly associated with maternal under perfusion and uteroplacental insufficiency. These are the reasons for preterm birth. Thus, knowledge of the etiological factor can be use to reduce maternal and neonatal morbidity and mortility. Keywords: Placenta, Term & Preterm.

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315 USE OF PERIFOLLICULAR BLOOD FLOW TO PREDICT THE DEVELOPMENTAL COMPETENCE OF BOVINE CUMULUS-OOCYTE COMPLEXES COLLECTED DURING REPEATED OVUM PICKUP SESSIONS ONCE OR TWICE WEEKLY

Reproduction Fertility and Development ◽

10.1071/rdv21n1ab315 ◽

2009 ◽

Vol 21 (1) ◽

pp. 254 ◽

Cited By ~ 1

Author(s):

A. Hanstedt ◽

K. Höffmann ◽

Ä Honnens ◽

H. Bollwein ◽

C. Wrenzycki

Keyword(s):

Blood Flow ◽

Blastocyst Stage ◽

Developmental Competence ◽

Small Individual ◽

Color Flow ◽

Color Flow Imaging ◽

Significant Difference ◽

Developmental Rates ◽

Group 2 ◽

Group 1

On average, only 20% of the cumulus–oocyte complexes (COC) develop to the blastocyst stage (Merton et al. 2003 Theriogenology 59, 651–674). An increase in the blood supply to individual follicles appears to be associated with follicular growth rates, whereas a reduction seems to be closely related to follicular atresia (Acosta et al. 2003 Reproduction 125, 759–767). The purpose of this study was to determine whether qualitative perifollicular blood flow changes can be used to predict the developmental competence of COC collected during repeated ovum pickup (OPU) sessions once or twice weekly. Lactating Holstein cows (n = 20) were used as oocyte donors. After dominant follicle removal, OPU was performed twice (group 1, for 3 weeks) or once (group 2, for six weeks) weekly employing a 7.5-MHz transducer (GE 8C-RS) of an ultrasound scanner (GE Logiq Book). Follicle size and Doppler characteristics were recorded by transvaginal ultrasonography just before COC collection using color flow imaging. Owing for technical limitations for measurement of blood flow in small individual follicles, only the presence or absence of blood flow was assessed for each follicle. When a clearly visible blue or red spot (blood flow) was detected in the follicle wall, it was considered as a follicle with detectable blood flow. Follicles with or without detectable blood flow from each individual cow were aspirated separately. After morphological classification of COC, standard protocols for IVP were used for embryo production (Wrenzycki et al. 2001 Biol. Reprod. 65, 323–331). Cleavage and blastocyst rates were recorded at Day 3 and Day 8, respectively. In total, 464 (246 with and 218 without detectable blood flow) and 243 (125 with and 118 without detectable blood flow) follicles ≥3 mm were aspirated in group 1 and group 2, respectively. Morphology of the COC was similar in all groups. Developmental rates for COC stemming from follicles with or without detectable blood flow in group 1 did not show differences for cleavage rates, 54.0% (34/63) and 56.7% (45/81), and for blastocyst rates, 25.4% (16/63) and 22.2% (18/83), respectively. In group 2, the cleavage rates were also similar for COC originating from follicles with and without detectable blood flow, 54.3% (25/46) and 51.5% (34/66). However, developmental rates up to the blastocyst stage did show a significant difference, 23.9% (11/46) and 15.2% (10/66) for COC aspirated from follicles with or without detectable blood flow (P ≤ 0.05). These results show that using COC originating from follicles with detectable perifollicular blood flow collected once weekly may have a higher developmental competence compared to those from follicle without detectable blood flow. Within the detection limits of this study, differences in perifollicular blood flow during repeated OPU sessions once weekly were predictive of oocyte competence. Ruthe Research Farm, Germany, for providing the animals; Masterrind GmbH, Germany, for donation of the semen; and the HW Schaumann Stiftung for financial support.

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313 EVALUATION OF COLOR DOPPLER ULTRASONOGRAPHY OF THE PERIFOLLICULAR BLOOD FLOW TO PREDICT THE DEVELOPMENTAL COMPETENCE OF BOVINE CUMULUS - OOCYTE COMPLEXES COLLECTED DURING REPEATED OVUM PICK-UP SESSIONS

Reproduction Fertility and Development ◽

10.1071/rdv20n1ab313 ◽

2008 ◽

Vol 20 (1) ◽

pp. 236

Author(s):

A. Hanstedt ◽

K. Höffmann ◽

Ä. Honnens ◽

H. Bollwein ◽

C. Wrenzycki

Keyword(s):

Blood Flow ◽

Color Doppler ◽

Developmental Competence ◽

Dominant Follicle ◽

In Vitro Production ◽

Small Individual ◽

Color Flow ◽

Color Flow Imaging ◽

Follicle Size ◽

Flow Changes

The population of cumulus–oocyte complexes (COCs) used in OPU–IVP (ovum pick-up combined with in vitro production of embryos) is largely homogeneous due to repeated sessions resulting in the elimination of dominant and atretic follicles, especially when a 3–4 day interval is used. However, on average only 20% of the COCs develop to the blastocyst stage (Merton et al. 2003 Theriogenology 59, 651–674). Different blood flow changes within the follicle wall influence the fate of the follicles, and detectable blood flow and vasculature are associated with follicle viability. Furthermore, blood flow in follicles may be involved in not only selection of the dominant follicle but also early follicular development including follicular recruitment (Miyamoto et al. 2006 J. Reprod. Dev. 52, 153–160). However, no data are available regarding the quality of the COCs collected from follicles with or without blood flow. The purpose of this study was to determine whether qualitative perifollicular blood flow changes can be used to predict the developmental competence of COCs collected during repeated OPU sessions. Lactating Holstein cows were used as oocyte donors. After dominant follicle removal, OPU was performed twice weekly employing a 7.5-MHz transducer (GE 8C-RS) of an ultrasound scanner (GE Logiq Book). Follicle size and Doppler characteristics (color flow imaging) were recorded by transvaginal ultrasonography just before COC collection. Due to technical limitations for measurement of blood flow in small individual follicles, only the presence or absence of blood flow was assessed for each follicle. When a clearly visible blue or red spot (blood flow) was detected in the follicle wall, it was considered as a follicle with detectable blood flow. Follicles with or without detectable blood flow from each individual cow were aspirated separately. After morphological classification of COCs, standard protocols for IVP were used for embryo production. Cleavage and blastocyst rates were recorded at Day 3 and Day 8, respectively. In total, 464 (246 with and 218 without detectable blood flow) follicles e3 mm were aspirated. The percentage of follicles with detectable blood flow increased depending on follicle size (3 mm: 28.7, 4 mm: 48.4, 5 mm: 50.5, 6 mm: 62.5, 7 mm: 64.8, 8 mm: 71.4, and 9 mm: 76.9). Cleavage rates for COCs stemming from follicles with or without detectable blood flow did not show differences, 45.5% (35/77) and 56.7% (38/67), respectively. The rates of blastocyst formation were also similar in COCs originating from follicles with and without detectable blood flow, 16.9% (13/77) and 14.9% (10/67), respectively. These results show that perifollicular blood flow increases during early follicular growth. Within the detection limits of this study, differences in perifollicular blood flow during repeated OPU sessions twice weekly did not seem to be predictive of oocyte competence. We acknowledge the Ruthe Research Farm, Germany, for providing the animals, and Masterrind GmbH, Germany, for donating the semen.

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Blood flow events visible in ultrasonic color flow imaging

10.1109/iembs.1989.95804 ◽

2003 ◽

Cited By ~ 1

Author(s):

R.L. Powis

Keyword(s):

Blood Flow ◽

Flow Imaging ◽

Color Flow ◽

Color Flow Imaging

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Efficacy of Transcranial Color Flow Imaging in Patients with Abnormal Blood Flow Velocity of the Middle Cerebral Artery

Neurosonology ◽

10.2301/neurosonology.7.71 ◽

1994 ◽

Vol 7 (2) ◽

pp. 71-75

Author(s):

Kentaro FUJISHIRO ◽

Kuniyasu KODAIRA ◽

Takashi WADA ◽

Ken-ichi MAIE ◽

Eiji TSUKIYAMA ◽

...

Keyword(s):

Blood Flow ◽

Middle Cerebral Artery ◽

Flow Velocity ◽

Cerebral Artery ◽

Blood Flow Velocity ◽

Flow Imaging ◽

Color Flow ◽

Color Flow Imaging

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Detection of endometrial cancer by transvaginal ultrasonography with color flow imaging and blood flow analysis: A preliminary report

International Journal of Gynecology & Obstetrics ◽

10.1016/0020-7292(92)90357-o ◽

1992 ◽

Vol 37 (4) ◽

pp. 328-328

Author(s):

Th Bourne ◽

S Campbell ◽

Cv Steer ◽

P Royston ◽

Mi Whitehead ◽

...

Keyword(s):

Blood Flow ◽

Endometrial Cancer ◽

Preliminary Report ◽

Flow Analysis ◽

Transvaginal Ultrasonography ◽

Flow Imaging ◽

Color Flow ◽

Color Flow Imaging ◽

Blood Flow Analysis

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An Advanced Filter Adaptive to Non-Stationary Clutter in Ultrasonic Color Flow Imaging

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.186.141 ◽

2011 ◽

Vol 186 ◽

pp. 141-145

Author(s):

Cong Sheng Xie ◽

Dong C. Liu

Keyword(s):

Blood Flow ◽

Adaptive Filter ◽

Constant Velocity ◽

Cutoff Frequency ◽

Flow Imaging ◽

Color Flow ◽

Flow Estimation ◽

Clutter Rejection ◽

Color Flow Imaging ◽

Tissue Motion

Traditional clutter rejection methods are based on the hypothesis that the clutter signal originates from stationary or moving tissue with a constant velocity, and they are not valid when there exists considerable acceleration of tissue motion. In this paper, we propose an advanced clutter filter adapted to accelerated tissue motion. It uses the instantaneous frequency to realize the DC remove, and uses the bandwidth of the clutter signal to choose the cutoff frequency of the wall filter, Simulation shows this advanced adaptive filter can efficiently attenuate the non-stationary clutter signals and improves the accuracy and the flexibility of the blood flow estimation.

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