scholarly journals Prevalence of anti-herpes simplex virus type 1 among dental students of Birjand University of Medical Sciences, Iran, 2017-2018: Short Communication

2021 ◽  
pp. 296-301
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Close Contact ◽  
Cross Sectional Study ◽  
Dental Students ◽  
Enzyme Linked Immunosorbent Assay ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Simplex Virus

Herpes simplex virus is considered one of the most common human infections in most parts of the world, among which, herpes simplex virus 1 (HSV-1) is one of the most important human pathogenic viruses that cause numerous skin and oral lesions. Practitioners of the dental profession and related fields are in close contact with numerous patients referring to dental clinics and are at risk of cross-infection. Regarding this, one of the infections that dental professionals are exposed to is herpes simplex virus infection. This study aimed to evaluate the level of HSV1 antibody among dental students of Birjand in 2018-2019. This cross-sectional study was performed on 100 dental students of Birjand University of Medical Sciences, Iran. After obtaining informed consent, a peripheral blood sample (5 ml) was collected from participants and the presence of anti-virus antibody was examined using an Anti-Herpes-1 IgG kit with the enzyme-linked immunosorbent assay. It was revealed that 41% of the subjects had anti-herpes type 1 antibodies. Based on data analysis, the prevalence of HSV1 antibody was higher in pre-clinical and clinical level than in basic science; however, there was no significant relationship between students' educational level and antibody prevalence.

scholarly journals Herpes Simplex Virus Type 1 Encephalitis: A Descriptive, Cross Sectional Study, 2011 - 2016, Iran

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Seyed Ali Dehghan Manshadi ◽  
Sharif Teimourian ◽  
Arash Seifi ◽  
Zoha Alinejadi ◽  
Nahid Sarahian ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Simplex Virus

A Cross-Sectional Study of Herpes Simplex Virus Types 1 and 2 in College Students: Occurrence and Determinants of Infection

1990 ◽  
Vol 162 (2) ◽  
pp. 306-312 ◽  
Author(s):  
J. J. Gibson ◽  
C. A. Hornung ◽  
G. R. Alexander ◽  
F. K. Lee ◽  
W. A. Potts ◽  
...  
Keyword(s):  
College Students ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Simplex Virus

scholarly journals Limits in Reliability of Glycoprotein G-Based Type-Specific Serologic Assays for Herpes Simplex Virus Types 1 and 2

1999 ◽  
Vol 37 (2) ◽  
pp. 376-379 ◽  
Author(s):  
D. Scott Schmid ◽  
Denise R. Brown ◽  
Rosane Nisenbaum ◽  
Rae Lyn Burke ◽  
D’Anna Alexander ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Western Blot ◽  
Validation Studies ◽  
Enzyme Linked Immunosorbent Assay ◽  
Western Blot Assay ◽  
Cross Sectional ◽  
Glycoprotein G ◽  
Simplex Virus ◽  
Hsv 1

Type-specific serologic assays for herpes simplex virus (HSV) types 1 and 2 based on glycoprotein G-1 (gG-1) (HSV-1) and gG-2 (HSV-2) discriminate between antibodies against HSV-1 and HSV-2. We previously developed a Western blot assay using gG-1 and gG-2 expressed in baculovirus, performed extensive validation studies, and determined that it was both sensitive and specific for type-specific detection of HSV antibody. Here we report that, among a cohort of Thai military recruits, the serostatus of some individuals changed from positive to negative over time (6.6% among those ever positive for HSV-1, and 14.9% among those ever positive for HSV-2). We tested a subset of these specimens in three other gG-based assays: an enzyme-linked immunosorbent assay, an immunoblot strip assay, and a Western blot assay. Positive-to-negative shifts occurred in every assay; the frequency of the shifts ranged from 6.1% to 21.2% of the specimen sets tested. There was only limited agreement among the assays concerning which individuals lost reactivity. This inaccuracy, exhibited by all of the assay protocols, was not predicted by validation studies employing specimens from cross-sectional studies and was most pronounced in HSV-2 testing. This argues for the inclusion of serial blood specimens in serologic assay validation procedures.

Seroprevalence of herpes simplex virus types 1 and 2 and correlates of infection in Jordan

2022 ◽  
pp. 095646242110601
Author(s):  
Samer F Swedan ◽  
Alia’ Darabseh
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Population Estimate ◽  
Enzyme Linked Immunosorbent Assay ◽  
Igg Antibodies ◽  
Cross Sectional ◽  
Simplex Virus ◽  
Hsv 1

Background Herpes infections are common infections among populations. Herein, a cross-sectional study was used to determine the seroprevalence of herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) IgG antibodies and their association with potential infection risk factors among Jordanians. Methods A total of 759 serum samples were collected (January to February 2020) and analyzed for HSV-1 and HSV-2 IgG antibodies by enzyme-linked immunosorbent assay. Estimates for population seropositivity were determined by weighting the age-specific seroprevalence by the size of the population in each age stratum. Results The population estimate for HSV-1 seroprevalence was 75.3%. After adjustment for possible confounders, regression analysis revealed higher seroprevalence with increase in age ( p < 0.005) and low household income ( p = 0.002). The population estimate for HSV-2 seroprevalence was 2.9%. No significant differences in HSV-2 seroprevalence were observed in association with age, gender, family size, educational level, and socioeconomic status, likely due to low seropositivity. Conclusions Jordanians have high HSV-1 and low HSV-2 seroprevalence. Periodical studies might be needed to evaluate changes in HSV-1 and HSV-2 seroprevalence over time. This study provides essential epidemiological data for Jordan and the Middle East and North Africa region.

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