Pregnancy Success Rates by Different Assisted Reproductive Techniques in Tubal, Ovarian, and Sperm Disorders

2020 ◽  
Vol 6 (3) ◽  
pp. 187-192
Author(s):  
Zeinab Hajaliakbari Hafezabad ◽  
◽  
Milad Ahmadi Gohari ◽  
Faezeh Kashi ◽  
◽  
...  
Keyword(s):  
Pregnancy Rate ◽  
Fertility Rate ◽  
Assisted Reproductive Techniques ◽  
World Health ◽  
Success Rates ◽  
Tubal Infertility ◽  
Vitro Fertilization ◽  
Significant Difference ◽  
Reproductive Techniques

Background: Assisted Reproductive Techniques (ART) have been used for addressing numerous causes of infertility. However, it remains unclear which kind of these methods are best for various infertility types. Accordingly, this study aimed at determining pregnancy success rates by different ART in tubal, ovarian, and sperm disorders. Methods: The present descriptive retrospective study used the records of individuals who had referred to the Infertility Center of Kerman University of Medical Sciences from March 2016 to December 2017. All subjects underwent Intracytoplasmic Sperm Injection (ICSI) and In Vitro Fertilization (IVF). The sperm parameters were assessed based on the criteria of the World Health Organization (WHO) for determining the causes of male infertility. The data were documented and compared with the criteria of the WHO. Then, they were analyzed by analysis of variance, Paired Samples t-test, Chi-squared, or Fisher’s Exact tests using SPSS. Results: The overall Mean±SD fertility rate in IVF and ICSI was 4.28±2.87 and 3.62±2.54, respectively and the difference was not significant (t=1.02, P=0.319). There was a significant difference in the fertility rate due to tubal infertility (P=0.018) between ICSI and IVF; the fertility rate in the IVF method was significantly higher than that of the ICSI. The pregnancy rate in the freeze method was higher than those of the other methods (P<0.001). This discrepancy was also found in all causes of infertility. There was no significant difference in the disorders of sperm and the result of two methods (IVF/ICSI). Conclusion: The obtained results suggested that in the freeze method, the pregnancy rate was higher than other approaches; this discrepancy was found in all the causes of infertility. It is suggested that frozen-thawed embryo transfer be used in infertile individuals. This is because it increases the success rate of pregnancy and prevents complications due to the repeated use of infertility treatments and exorbitant treatment costs.

scholarly journals The effectiveness of collaborative infertility counseling (CIC) on pregnancy outcome in infertile women undergoing in vitro fertilization: A randomized controlled trial

2019 ◽  
Author(s):  
Mahboobeh Rasoulzadeh Bidgoli ◽  
robab latifnejad roudsari ◽  
ali montazeri
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Rate ◽  
Treatment Success ◽  
Intervention Group ◽  
Control Group ◽  
Vitro Fertilization ◽  
Infertile Women ◽  
Significant Difference ◽  
And Control

Abstract Background: Infertility is an emotional tension which influences the whole aspects of relationships in infertile couples. A main objective of infertility treatments is elevation of pregnancy rate. The present study aimed to examine the effect of collaborative counseling on pregnancy rate in infertile women, undergoing in vitro fertilization in Mashhad, Iran. Methods: In this clinical trial, 60 women with primary infertility were selected from an infertility research center and were randomly allocated into intervention (n=29) and control (n=31) groups. The intervention group received individual counseling, based on the collaborative reproductive healthcare model with collaboration of a midwife, a gynecologist and a clinical psychologist in five sessions during a two-month period. The control group received routine care. Positive pregnancy test was considered as a criterion of treatment success at the end of the study. Data were analyzed using statistical tests including independent samples t-test. Results: There was no significant difference in pregnancy rate between intervention and control groups (P = 0.298). Also, there were no significant differences in follicle and embryo numbers between two groups. However, a significant difference was observed between two groups in terms of oocyte numbers where the intervention group had more oocyte (P = 0.014). Conclusion: Overall the findings indicated that the collaborative infertility counseling did not improve treatment success in infertile women undergoing in vitro fertilization

The effectiveness of tubal infertility treatment in ART programs depending on ovarian stimulation protocol

2017 ◽  
pp. 114-116
Author(s):  
O.V. Bagatko ◽  
◽  
N.O. Dankovich ◽  
Keyword(s):  
Ovarian Stimulation ◽  
Treatment Effectiveness ◽  
Medical Center ◽  
Medical Documentation ◽  
Stimulation Protocol ◽  
Tubal Infertility ◽  
Vitro Fertilization ◽  
Significant Difference ◽  
Long Protocol

The objective: of the investigation was to study the effectiveness of treatment of women with tubal infertility, depending on the protocol of ovarian stimulation. Materials and methods. To achieve tht goal, the medical documentation of patients who contacted the «Mother and Child» Medical Center in 2012-2013 was analyzed. To compare the efficacy of different ovarian stimulation protocols were selected 387 patients under the age of 35 years with tubal infertility, who were stimulated by standard protocols with further separation into two groups: S (short stimulation protocol, n=246) and L (long stimulation protocol, n=141). In both groups, an intracytoplasmic sperm injection (ICSI) was performed. Results.The mean duration of stimulation in a long protocol was on 2 days longer. The total amount of spent rFSH was also significantly (by 300 IU) more. There was no significant difference between the number of blastocysts and high quality blastocysts. The cumulative efficacy of treatment after 1 year was 82.33% and 77.30% (p>0.05). Conclusion. The retrospective study showed that women with tubal infertility in a long protocol require a longer stimulation, using a larger total dose of recombinant FSH, with the same end-point effectiveness. Key words: tubal peritoneal infertility, in vitro fertilization, stimulation of superovulation, treatment effectiveness.

Insemination, in vitro fertilization, and intracytoplasmic sperm injection

2011 ◽  
pp. 1440-1447
Author(s):  
Herman J. Tournaye
Keyword(s):  
Assisted Reproduction ◽  
Male Partner ◽  
Specific Treatment ◽  
Clinical Work ◽  
Primary Treatment ◽  
Assisted Reproductive Techniques ◽  
Vitro Fertilization ◽  
Reproductive Techniques ◽  
Work Up

Anamnesis, physical examination, and additional tests may reveal a specific cause of reproductive failure in infertile men. Whenever this is found, a specific treatment or cure should be applied. When no such treatment is available, or when specific treatment has failed, techniques of assisted reproduction may be proposed to couples suffering from long-standing male infertility. The rationale behind these is to bring the spermatozoa closer to the oocyte in an attempt to enhance the fertilization process. In recent years the role of assisted reproduction has become more important, and it has often been stated that these techniques have made clinical work-up or specific treatment of the male partner pointless. However, this is far from true. Not only may correction of a specific dysfunction in the male avoid the use of assisted reproductive techniques, but careful work-up and treatment may also enhance the outcome of these treatments. Assisted reproductive techniques should not be viewed as a primary treatment option, but rather as a complementary treatment when other treatments have failed, or have been judged inadequate after a complete work-up.

Editorial-SURROGACY

2016 ◽  
Vol 32 (2) ◽  
Author(s):  
O.S. Verma
Keyword(s):  
In Vitro Fertilization ◽  
Intrauterine Insemination ◽  
Natural Course ◽  
Assisted Reproductive Techniques ◽  
Egg Donation ◽  
Surrogate Mother ◽  
Vitro Fertilization ◽  
Reproductive Techniques

Worldwide, about 200 million couples are infertile. Almost 15 per cent of them require ART and IVF treatments. Couples who are unable to conceive even after years of trying could use procedure called Assisted Reproductive Techniques (ART) to get pregnant. These includes Intrauterine Insemination, In-Vitro Fertilization (IVF), Spern / Egg donation, and Gestational Carriers called “Surrogacy”. People join for Surrogacy when they want to have their genes in the child but can not make it happen in natural course. There are two types of Surrogacy: (1) The man’s sperm and the woman’s ova is injected in the uterus of the surrogate mother who rents out her womb for the child, (2) If the Egg of the mother is not good enough to produce a baby, an Egg is then rented out by donor mother. A tripartite agreement is duly signed according to the terms and conditions prevalent at that time. This Editorial viewed Surrogacy Industry through the lens of intent, efficacy, and its purview.

scholarly journals Development of ICSI

Reproduction ◽  
2018 ◽  
Vol 156 (1) ◽  
pp. F51-F58 ◽  
Author(s):  
C L O’Neill ◽  
S Chow ◽  
Z Rosenwaks ◽  
G D Palermo
Keyword(s):  
Pregnancy Rate ◽  
Human Body ◽  
Assisted Reproductive Techniques ◽  
Semen Parameters ◽  
Male Factor Infertility ◽  
Fertilization Failure ◽  
Male Factor ◽  
Reproductive Techniques

The first conception outside of the human body that led to the birth of Louise Brown was a tremendous accomplishment, which opened the door to the utilization of assisted reproductive techniques globally. This brought the understanding that accomplishing life in a dish required several steps, the most obvious being the timing and characteristics of fertilization. It soon became obvious in the 1980s that the most disappointing phenomenon was unexpected and complete fertilization failure. Among the approaches that were attempted to treat male factor infertility, ICSI surfaced as the technique that brought the ratio of the gametes to 1:1 and was also able to grant consistent fertilization and a higher pregnancy rate. ICSI has now been implemented for a quarter of a century, proving itself as the ultimate technique utilizing ejaculated spermatozoa independent of the semen parameters and is the sole insemination method to be used with surgically retrieved spermatozoa. There are currently various indications for ICSI that are widely adopted, rendering it the most popular insemination method worldwide. The reliability of ICSI ensures its employment in upcoming techniques involving in vitro spermatogenesis and neogametogenesis.

scholarly journals Ectopic pregnancy as a complication after assisted reproductive techniques. Case report

2021 ◽  
pp. 548-551
Author(s):  
Marina A. Kiyok ◽  
Keyword(s):  
Ectopic Pregnancy ◽  
Fallopian Tube ◽  
Assisted Reproductive Techniques ◽  
Highly Qualified ◽  
Vitro Fertilization ◽  
Abdominal Bleeding ◽  
Precise Diagnosis ◽  
Reproductive Techniques ◽  
Ectopic Pregnancies

Ectopic pregnancy (EP) is a rare and severe complication of assisted reproductive techniques (ART). A specific feature of EP after ART is a high frequency of rare atypical forms of EP, the absence of a specific clinical picture and a high probability of recurrent EP, which makes certain difficulties in terms of diagnosis. Interstitial pregnancies occur in 1–6% of all ectopic pregnancies and in 7.3% cases of EB which were the results of in vitro fertilization programs (IVF). The anatomical features of the blood supply in the intramural segment of the fallopian tube provide favorable conditions for the progression of pregnancy on the average up to 10 weeks of gestation, simulating the intra-uterine pregnancy. Chorionic villi, growing into the thickness of the myometrium, create a high risk of profuse intra-abdominal bleeding. The article presents a clinical case of a rare form of ectopic pregnancy in the interstitial segment of the fallopian tube after IVF. The patient had previously undergone a bilateral salpingectomy by tubal pregnancies. This clinical example shows the meaning of precise diagnosis and timely provision of highly qualified specialized medical care.

15 QUANTIFICATION OF BULL SPERM TRAITS AS ASSESSED BY COMPUTER-ASSISTED SEMEN ANALYSIS AND THE RELATIONSHIP TO PREGNANCY RATE FOLLOWING CONTROLLED BREEDING

2017 ◽  
Vol 29 (1) ◽  
pp. 115
Author(s):  
M. L. Mphaphathi ◽  
M. M. Seshoka ◽  
F. V. Ramukhithi ◽  
Z. C. Raphalalani ◽  
T. R. Netshirovha ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Rate ◽  
Semen Analysis ◽  
Computer Assisted ◽  
Vitro Fertilization ◽  
Significant Difference ◽  
Bull Sperm ◽  
Sperm Traits

The bull’s contribution through artificial insemination to reproductive efficiency is of great biological importance. The objectives were (1) to compare the oestrous synchronization response of Bonsmara and Nguni cows; and (2) to find the relationship between cow’s conception rate (in vivo and in vitro fertilization) and bull sperm motility rate assessed by computer-assisted semen analysis (CASA) following AI. For the in vivo sperm fertility test, 100 Bonsmara and 482 Nguni cows were randomly selected and subjected to oestrous synchronization protocol and AI with frozen–thawed assessed semen by CASA before AI. Briefly at Day 0, cows were inserted with an intravaginal CIDR® (1.9 g), which was removed on Day 7. Prostaglandin was then administered (2 mL) on Day 8 and a heatmount detector was placed on the hindquarter of each cow. For the in vitro sperm fertility test, collected oocytes from slaughterhouse were in vitro matured (n = 360) and in vitro fertilized (sperm/mL) in 100-µL droplets (final volume) of BO-IVF medium per treatment bulls (Bonsmara or Nguni bull). The frozen/thawed semen straws of Bonsmara and Nguni bulls were randomly selected and used under the same IVF conditions. The thawed bull’s sperm characteristics were examined by CASA before in vitro fertilization. Data were analysed using ANOVA. Treatment means were compared using the Fisher’s protected least significant difference t-test. There was no significant difference in oestrous response for the Bonsmara (83.0%) and Nguni (90.8%) cows, respectively. The Bonsmara cows recorded a significantly higher pregnancy rate (59.0%) compared with the Nguni (37.1%) cows (P < 0.05). Sperm traits such as total motility (TM), progressive motility and rapid were found to be positively correlated with conception rate (r = 0.06, 0.03, and 0.08, respectively; P < 0.01), although correlations were low. There was no difference in the average frozen–thawed sperm TM rate of Nguni (92.2%) and Bonsmara (81.0%). There was a lower fertilization rate following IVF with Bonsmara and Nguni bull sperm. In conclusion, Nguni cows had similar oestrous response as Bonsmara cows. The sperm traits from Bonsmara and Nguni bulls were found to be related to in vivo conception and in vitro fertilization rate when sperm cells were assessed by CASA technology. However, the pregnancy rate was lower in Nguni cows.

Factors causing stress in women undergoing in-vitro fertilization treatment

2020 ◽  
Vol 10 (1) ◽  
pp. 43-51
Author(s):  
Z Sökmen ◽  
S Türkleş
Keyword(s):  
In Vitro Fertilization ◽  
Support Groups ◽  
Descriptive Study ◽  
Infertility Treatment ◽  
Study Data ◽  
Assisted Reproductive Techniques ◽  
Vitro Fertilization ◽  
State Hospitals ◽  
Reproductive Techniques

Purpose: This descriptive study was conducted to identify the factors causing stress in women undergoing in-vitro fertilization (IVF) treatment. Materials and methods: The study sample consisted of 151 women who were receiving IVF therapy in the assisted reproductive techniques units of three state hospitals in Istanbul. The study data were collected using a Questionnaire and a Distress/Problem Identification form both developed by the investigators. Results: A considerable percentage of the women whose income was less than their expenses stated that they feared their infertility treatment would be a failure. The majority of the women who gave the answer “the cause is not known” or “me” when they are asked “who is responsible for not being able to have a child” stated that they were annoyed when people asked questions about having children and felt strained and uneasy on the days of coming to the center. Conclusions: We suggest that trainings should be planned for health teams and health teams should establish support groups and organize meetings for couples

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