scholarly journals Progesterone Receptor Gene Polymorphism Promoter Region +331G/A Increases Risk of Endometriosis

2016 ◽  
pp. 52-56
Author(s):  
Syifa Alkaf ◽  
Aerul Chakra ◽  
Usman Said ◽  
Irsan Saleh
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphism ◽  
Promoter Region ◽  
Receptor Gene ◽  
Case Group ◽  
Progesterone Receptor Gene ◽  
Pcr Rflp ◽  
Increase Risk ◽  
Study Population ◽  
Control Study

Objective: To identify relationship between progesterone receptor gene polymorphism promoter region +331G/A with the risk of endometriosis. Method: An observational case-control study. Population are women with endometriosis and/or adenomyosis who have been performed laparotomy/laparoscopy at Obstetrics and Gynecology Department Dr. Mohammad Hoesin General Hospital Palembang, January-November 2013. Subjects fulfilled inclusion criteria, given informed consent and performed blood sampling continued by PCRRFLP. Results were divided into A/A genotype (homozygote mutant), G/A (heterozygote mutant), and G/G (homozygote wild type). Data were analyzed by SPSS 21.0 version. Result: PCR-RFLP results for+331G/A genotype were 26 (54.1%) in case group and 14 (26.4%) in control. +331A/A genotype was not found in both groups. There was significant increase risk of endometriosis in women carrying genotype +331G/A to those with genotype +331G/G with OR 3.29 (p

Genetics of endometriosis: a role for the progesterone receptor gene polymorphism PROGINS?

2004 ◽  
Vol 61 (2) ◽  
pp. 190-194 ◽  
Author(s):  
Debora Lattuada ◽  
Edgardo Somigliana ◽  
Paola Vigano ◽  
Massimo Candiani ◽  
Giorgio Pardi ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphism ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Progesterone Receptor Gene

scholarly journals Association of progesterone receptor gene polymorphism with male infertility and clinical outcome of ICSI

2013 ◽  
Vol 30 (9) ◽  
pp. 1133-1139 ◽  
Author(s):  
Sanjukta Sen ◽  
Abhijit Dixit ◽  
Chitra Thakur ◽  
Jyotsna Gokral ◽  
Indira Hinduja ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Clinical Outcome ◽  
Male Infertility ◽  
Gene Polymorphism ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Progesterone Receptor Gene

scholarly journals Polymorphism and association of progesterone receptor gene with milk production and reproductive traits of rabbits

2020 ◽  
Vol 65 (No. 9.) ◽  
pp. 346-353
Author(s):  
Lubomir Ondruska ◽  
Vladimir Parkanyi ◽  
Jan Rafay ◽  
Alica Navratilova
Keyword(s):  
Progesterone Receptor ◽  
Milk Production ◽  
Litter Size ◽  
Association Studies ◽  
Receptor Gene ◽  
Reproductive Traits ◽  
Genotype Frequencies ◽  
Progesterone Receptor Gene ◽  
Pcr Rflp ◽  
Genotype A

Using the PCR RFLP method polymorphism and three different genotypes (AA, AG and GG) were detected in the progesterone receptor gene (PGR) promoter in a local Slovak crossbred rabbit line. We have noted a slightly majority frequency of allele A (0.53) over allele G (0.47). Comparing the observed and expected genotype frequencies with the χ<sup>2</sup> test the results were statistically significant, which means the tested rabbit population was non-equilibrium. The best results and significantly highest milk production (P &lt; 0.001) were recorded in the does of GG genotype compared to AA genotype. Other association studies aimed at the effect of genotypes on litter size showed the highest litter size and number of weaned rabbits per litter in GG genotype. A significantly higher (P &lt; 0.05) average number of stillborn kits per litter was in the group of does with AA genotype (0.62) compared with GG genotype (0.34).

Association of the progesterone receptor gene polymorphism (PROGINS) with endometriosis: a meta-analysis

2014 ◽  
Vol 290 (5) ◽  
pp. 1015-1022 ◽  
Author(s):  
Noel Pabalan ◽  
Alice Salvador ◽  
Hamdi Jarjanazi ◽  
Denise Maria Christofolini ◽  
Caio Parente Barbosa ◽  
...  
Keyword(s):  
Progesterone Receptor ◽  
Gene Polymorphism ◽  
Meta Analysis ◽  
Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Progesterone Receptor Gene
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