scholarly journals Application of sorbitol based infusion preparation for normalization of water-electrolyte exchange in surgery patients with direct rectal cancer

2020 ◽  
pp. 18-18
Author(s):  
Ye.S. Varyvoda ◽  
I.Ya. Orishchin ◽  
V.M. Lutsiv ◽  
V.Ye. Varyvoda ◽  
B.R. Dzis ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Anterior Resection ◽  
Postoperative Period ◽  
Early Postoperative Period ◽  
Electrolyte Metabolism ◽  
Potassium Sodium ◽  
Sodium Calcium ◽  
Intravenous Infusions ◽  
Complex Drug

Objective. To study the effect of intravenous infusions of the complex drug Rheosorbilact polyfunctional action on the indicators of water-electrolyte metabolism in operated patients with rectal cancer after anterior resection of the rectum in the early postoperative period. Materials and methods. Clinical application of the complex drug Rheosorbilact of multifunctional action was carried out in 30 patients with rectal cancer after the operation of anterior resection of the rectum in the early postoperative period. Studies of plasma electrolytes in operated patients were performed before surgery, on the 1st day after surgery, and on the 2nd, 3rd, 5th day after administration of the drug Rheosorbilact. Results. As a result of studies in patients with colorectal cancer after anterior resection of the rectum in the first days after surgery revealed a decrease in potassium, sodium, calcium in blood plasma. To correct the indicators of water-electrolyte metabolism in operated patients after anterior resection of the rectum immediately after surgery intravenously injected infusion drug Rheosorbilact multifunctional action. After repeated, within 5 days, intravenous infusions of the drug Rheosorbilact, revealed normalization of the concentrations of potassium, sodium, calcium in blood plasma in operated patients with colorectal cancer. Conclusions. Repeated intravenous infusions of the complex drug Rheosorbilact multifunctional action lead to normalization of water-electrolyte metabolism in patients with colorectal cancer after anterior resection of the rectum in the early postoperative period. Normalization of water-electrolyte metabolism in operated patients is confirmed by the content of potassium, sodium and calcium ions in the infusion drug Rheosorbilact. Rheosorbilact is recommended for widespread medical use in such patients, especially in the early postoperative period.

scholarly journals Application of sorbitol-based infusion preparation for normalization of biochemical indicators in the blood in surgery patients with direct rectal cancer

2020 ◽  
pp. 17-17
Author(s):  
Ye.S. Varivoda ◽  
I.Ya. Orishchin ◽  
V.M. Lutsiv ◽  
V.Ye. Varivoda ◽  
B.R. Dzis ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Blood Glucose ◽  
Anterior Resection ◽  
Postoperative Period ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Early Postoperative Period ◽  
Intravenous Infusions ◽  
Complex Drug

Objective. To study the effect of intravenous infusions of the complex drug Rheosorbilaсt polyfunctional action on the biochemical parameters in the blood in operated patients with rectal cancer after anterior resection of the rectum in the early postoperative period. Materials and methods. The study of biochemical parameters in the blood of 30 patients with colorectal cancer was performed in the first days after surgery, and on the 2nd, 3rd, 5th day after administration of the drug Rheosorbilact. The drug was administered intravenously at a rate of 40 drops per minute. The daily dose of Rheosorbilact was 800.0 ml. Results. As a result of biochemical studies in patients with colorectal cancer, in the first days after anterior resection of the rectum revealed a decrease in total protein, increased concentrations of urea, creatinine and blood glucose. To correct the biochemical parameters in the blood of such patients immediately after surgery was administered intravenous infusion of Rheosorbilact. After repeated intravenous infusions of Rheosorbilact for 5 days, a significant increase in total protein content, a significant decrease in the concentration of urea, creatinine and blood glucose in the operated patients was found. Therefore, multiple intravenous infusions of the complex drug Rheosorbilact multifunctional action lead to the normalization of biochemical parameters in the blood. Conclusions. In patients with rectal cancer after anterior resection of the rectum in the first days after surgery revealed a decrease in total protein, increased concentrations of urea, creatinine and blood glucose. Repeated intravenous infusions of the complex drug Rheosorbilact multifunctional action normalize the biochemical parameters in the blood in operated patients with rectal cancer after anterior resection of the rectum in the early postoperative period. Rheosorbilact infusion is recommended for widespread medical use in such patients, especially in the early postoperative period.

scholarly journals INFLUENCE OF DEFUNCTIONING COLOSTOMY AFTER LOW ANTERIOR RESECTION FOR RECTAL CANCER ON EARLY POSTOPERATIVE PERIOD

2017 ◽  
pp. 34-39
Author(s):  
D. V. Zitta ◽  
V. M. Subbotin
Keyword(s):  
Rectal Cancer ◽  
Anastomotic Leakage ◽  
Anterior Resection ◽  
Postoperative Period ◽  
Low Anterior Resection ◽  
Fast Track ◽  
Early Postoperative Period ◽  
Hartmann Procedure ◽  
Postoperative Anastomotic Leak ◽  
Time Of Operation

The AIM of this study was to evaluate the influence of defunctioning colostomy after low anterior resection for cancer on early postoperative period and effectiveness of Fast Track protocol. MATERIALS. Retrospective analysis of medical records of 186 patients with rectal cancer who underwent anterior resection of the rectum in our department was done. All patients were allocated into 2 groups - conventional (had conventional perioperative care) and optimized (perioperative treatment according to Fast Track protocol). Both groups were subdivided into 3 subgroups (unprotected anastomosis, defunctioning colostomy and Hartmann procedure). The following data were analysed: average time of operation, operative bloodloss, volume of infusion and urination, time of mobilization removement of dranages and catheters, postoperative complications. RESULTS. Age, sex, comorbidities had no effect on decision about a preventive colostomy. The main reason for preventive colostomy was a middle-rectum location of a tumor. Preventive colostomy didn’t affect the course of early postoperative period in groups. Defunctioning colostomy effectively prevent catastrophic consequences of anastomotic leakage and didn’t compromise Fast Track protocol. CONCLUSION. Defunctioning colostomy did not reduce postoperative anastomotic leak rate, but mitigate consequences of an anastomotic leakage. Defunctioning colostomy did not affect the course of early postoperative period and Fast Track protocol.

scholarly journals PREVENTIVE COLOSTOMY IN PLANNED TREATMENT OF PATIENTS WITH RECTAL CANCER

2015 ◽  
Vol 174 (4) ◽  
pp. 24-29 ◽  
Author(s):  
N. A. Maistrenko ◽  
A. A. Khvatov ◽  
A. A. Sazonov ◽  
S. N. Petrov
Keyword(s):  
Rectal Cancer ◽  
Postoperative Period ◽  
Original Method ◽  
Early Postoperative Period

The article described an original method of forming preventive colostomy, which reduced the rate of incompetence of interintestinal anastomosis in sphinctersaving resection concerning rectal cancer. This also facilitated patient’s rehabilitation in early postoperative period.

scholarly journals Application infusion drugs based on sorbitol for normalization of aminotransferase activity blood cancer patients operated cardia of the stomach

2020 ◽  
pp. 29-30
Author(s):  
B.R. Dzis ◽  
S.V. Prymak ◽  
R.P. Dzis ◽  
V.L. Novak ◽  
M.P. Dzisiv ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Postoperative Period ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Proximal Gastrectomy ◽  
Early Postoperative Period ◽  
Aminotransferase Activity ◽  
Cardiac Cancer ◽  
Intravenous Infusions ◽  
In Blood Plasma

Objective. To study the effect of intravenous infusions of Rheosorbilact on the activity of alanine aminotransferase and aspartate aminotransferase in the plasma of operated patients with gastric cardiac cancer after proximal gastrectomy. Materials and methods. Alanine aminotransferase and aspartate aminotransferase activity levels were studied in plasma of 40 operated patients with gastric cardiac cancer after proximal gastrectomy immediately after surgery, on the 1st, 2nd, 3rd, 5th day after intravenous infusions of the drug. The infusion of Rheosorbilact was administered intravenously, drip, for 5 days at a rate of 40 drops per minute. The daily dose of the drug was 1000.0 ml. Results. In patients with gastric cardiac cancer after proximal gastrectomy in the first days after surgery revealed changes in aminotransferases, which are accompanied by an increase in the activity of alanine aminotransferase and aspartate aminotransferase in blood plasma. To correct the activity of plasma aminotransferases in such patients, Rheosorbilact was administered intravenously immediately after surgery. After repeated intravenous infusions of Rheosorbilact for 5 days, a significant decrease in the activity of alanine aminotransferase and aspartate aminotransferase in blood plasma in the operated patients was revealed. Conclusions. In the first days after proximal gastrectomy in patients with gastric cardiac cancer, an increase in the activity of aminotransferases in blood plasma was revealed. Repeated intravenous infusions of Rheosorbilact normalize the activity of alanine aminotransferase and aspartate aminotransferase in the blood plasma of such patients in the early postoperative period. Infusion drug Rheosorbilact is recommended for widespread medical use in patients with cardiac gastric cancer after proximal gastrectomy, especially in the early postoperative period.

scholarly journals Self-rating depression during early postoperative period after colostomy following radical surgery for rectal cancer

2018 ◽  
Vol 5 (1) ◽  
pp. 75-81
Author(s):  
Xue Hao ◽  
Ma Liying ◽  
Zhong Ming ◽  
Jay Shah
Keyword(s):  
Rectal Cancer ◽  
Cancer Patients ◽  
Postoperative Period ◽  
Radical Surgery ◽  
Normal Population ◽  
Multiple Logistic Regression Analysis ◽  
Depression Scale ◽  
Early Postoperative Period ◽  
Rectal Cancer Surgery ◽  
Self Rating

Introductions: Colorectal cancer (CRC) is 3rd most common cancer. Half of which requires colostomy. It leads to anxiety and depression with less than optimal quality of life. Zung Self-rating Depression Scale is a reliable tool used in Chinese population for identifying and addressing mental health status for appropriate education. The aim of this study is to investigate the depression state in rectal cancer patients after colostomy, then analyze its influence factors. Methods: A cross sectional study in rectal cancer patients who had colostomy after radical surgery for rectal cancer were investigated for depression during early postoperative period within one week using Zung’s self-rating depression scale (SDS). Multiple logistic regression analysis was done to identify the risk factor. Results: There were 55 colostomies patients (male 30 and female 25 patients, age 50.11+/-13.17 years) after rectal cancer surgery during the study period. The SDS score of was higher than national norm (P<0.01). The risk factors for depression were female gender, younger age, lower economic status, and lesser degree of understanding of the disease. Conclusions: The depression level of rectal cancer patients after colostomy was higher than normal population, especially in female, young age, with poor understanding of disease and lower economy status. The effective measures should be targeted to strengthen the health psychosocial health of these patients.

Arterial ligation in anterior resection for rectal cancer: A validation study of the Swedish Colorectal Cancer Registry

2014 ◽  
Vol 53 (7) ◽  
pp. 892-897 ◽  
Author(s):  
Petrus Boström ◽  
Jörgen Rutegård ◽  
Markku Haapamäki ◽  
Peter Matthiessen ◽  
Martin Rutegård
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Cancer Registry ◽  
Validation Study ◽  
Anterior Resection ◽  
Arterial Ligation

scholarly journals Serum and Erythrocyte Antioxidant Defense in Colorectal Cancer Patients during Early Postoperative Period: Potential Modifiers and Impact on Clinical Outcomes

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 999
Author(s):  
Małgorzata Krzystek-Korpacka ◽  
Magdalena Mierzchała-Pasierb ◽  
Marek Zawadzki ◽  
Dorota Diakowska ◽  
Wojciech Witkiewicz
Keyword(s):  
Colorectal Cancer ◽  
Antioxidant Capacity ◽  
Clinical Outcomes ◽  
Postoperative Period ◽  
Time Course ◽  
Early Postoperative Period ◽  
Sod Activity ◽  
Colorectal Cancer Surgery ◽  
Baseline Serum ◽  
Antioxidant Power

A better understanding of antioxidant status, its modifiers, and its effect on clinical outcomes in patients undergoing colorectal cancer surgery is needed for effective antioxidant-based interventions. The objectives of this cohort study were: to determine baseline serum (total antioxidant capacity (TAC) and ferric reducing antioxidant power (FRAP); n = 72) and erythrocyte (superoxide dismutase (SOD) and glutathione peroxidase (GPx); n = 47) antioxidant capacity and time-course during the 72 h postoperative period, to identify potential modifiers, and to establish impact on clinical outcomes. Older patients with comorbidities had lower baseline FRAP. TAC was inversely and SOD directly correlated with inflammatory markers. Cancer pathology affected GPx (lower in advanced and more aggressive cancers) and SOD (higher in advanced cancers). Surgical intervention induced a transient increase in FRAP and TAC with greater FRAP elevation in older, obese patients with several comorbidities. SOD activity significantly increased while GPx non-significantly decreased between 8 and 24 h post-incision. Poorer health status was associated with an increase in SOD and a decrease in GPx at 72 h. Clinical manifestation of postoperative ileus was preceded by decreased TAC at 24 h and an increase in SOD between 8 and 24 h and anastomotic leak was manifested by diminished SOD at 72 h compared to activities at 8 and 24 h. The time-frame between 8 and 24 h post-incision might be the most critical regarding oxidant/antioxidant balance and therefore the best suited for antioxidant-based intervention.

scholarly journals 100 ROBOTIC-ASSISTED OPERATIONS IN COLORECTAL CANCER (FIRST OUTCOMES)

2015 ◽  
Vol 174 (6) ◽  
pp. 80-84 ◽  
Author(s):  
D. V. Gladyshev ◽  
S. A. Kovalenko ◽  
M. E. Moiseev ◽  
S. S. Gnedash ◽  
A. M. Karachun ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Nodes ◽  
Hospital Stay ◽  
Postoperative Period ◽  
Early Postoperative Period ◽  
Treatment Results ◽  
Robotic Assisted ◽  
Significant Difference ◽  
First Results

This article analyzed the immediate treatment results of 210 patients, underwent endovideosurgical operative treatment concerning colorectal cancer (106 laparoscopic and 104 robotic-assisted operations). According to the first results, there was no significant difference between two methods in such medical indices as the volume of intraoperative hemorrhage, terms of hospital stay and peristalsis recovery, the rate of conversion and complications in early postoperative period, quantity of removed lymph nodes, quality of TME. The application of robotics allowed performance of precision work in conditions of limited space of the small pelvis.

Sign in / Sign up

Export Citation Format

Share Document