scholarly journals Bioactive Borate-Based Glass Coatings For Titanium Alloy Femoral Stems

2021 ◽  
Author(s):  
Yiming Li
Keyword(s):  
Hip Replacement ◽  
Bone Repair ◽  
Glass Powder ◽  
Double Cantilever Beam ◽  
Coefficient Of Thermal Expansion ◽  
Strontium Oxide ◽  
Ha Coating ◽  
Femoral Stems ◽  
The Mean ◽  
Glass Series

Hydroxyapatite (HA)-coated Ti6Al4V stems are currently used in total hip replacement (THR) surgeries. However, the residual stress in the HA coating due to mismatch in coefficient of thermal expansion (CTE) between HA and Ti6Al4V limits their application. Borate-based glasses can be promising alternatives to HA because of their similar CTEs to that of Ti6Al4V and excellent bioactivity that can promote bone repair. In this project, six borate-based glasses (Ly-B0, Ly-B1, Ly-B2, Ly-B3, Ly-B4, Ly-B5) from the B2O3-P2O5-CaO-Na2O-TiO2-SrO series were formulated by increasing the concentration of strontium oxide (SrO)from 0 to 25 in mol% at the expense of B2O3 in the glass series. Increased SrO content induced larger amounts of non-bridging oxygens and resulted in gradual increases in glass transition temperature (Tg). Discs of each glass powder were immersed in de-ionized water under 1, 7 and 30 days, and then the water extracts were used to determine the solubility and osteo-stimulatory effect of the glasses. Sr2+ doping retarded the dissolution rate of the glasses and the higher levels of Sr2+ doping (20 mol% and 25 mol%) promoted proliferation of osteoblasts. Except for Ly-B5 (containing 25 mol% SrO), discs of each glass powder exhibited bacteriostatic behavior against Staphylococcus aureus after 24 hours exposure. The glasses were enamelled onto Ti6Al4V substrates, and then bi-layer double cantilever beam (DCB) specimens were manufactured to measure the Mode I (GIC) and Mode II (GIIC) energy release rate of the glass coating/Ti6Al4V constructs. The mean GIC values increased from 6.56 ± 0.9 to 14.6 1 ± 2.1 J/m2 with increasing SrO content from Ly-B0 to Ly-B5, and the mean GIIC values increased from 36.07 ± 3.8 to 46.92 ± 3.3 J/m2 with increasing SrO content from Ly-B0 to Ly-B5, indicating that the incorporation of 15-25 mol% SrO significantly increased the fracture toughness of the construct. Moreover, the GIC and GIIC values of the coating/substrate system for all the six glasses significantly reduced (p ≤ 0.05) due to degradation in de-ionized water.

scholarly journals Bioactive Borate-Based Glass Coatings For Titanium Alloy Femoral Stems

2021 ◽  
Author(s):  
Yiming Li
Keyword(s):  
Hip Replacement ◽  
Bone Repair ◽  
Glass Powder ◽  
Double Cantilever Beam ◽  
Coefficient Of Thermal Expansion ◽  
Strontium Oxide ◽  
Ha Coating ◽  
Femoral Stems ◽  
The Mean ◽  
Glass Series

Hydroxyapatite (HA)-coated Ti6Al4V stems are currently used in total hip replacement (THR) surgeries. However, the residual stress in the HA coating due to mismatch in coefficient of thermal expansion (CTE) between HA and Ti6Al4V limits their application. Borate-based glasses can be promising alternatives to HA because of their similar CTEs to that of Ti6Al4V and excellent bioactivity that can promote bone repair. In this project, six borate-based glasses (Ly-B0, Ly-B1, Ly-B2, Ly-B3, Ly-B4, Ly-B5) from the B2O3-P2O5-CaO-Na2O-TiO2-SrO series were formulated by increasing the concentration of strontium oxide (SrO)from 0 to 25 in mol% at the expense of B2O3 in the glass series. Increased SrO content induced larger amounts of non-bridging oxygens and resulted in gradual increases in glass transition temperature (Tg). Discs of each glass powder were immersed in de-ionized water under 1, 7 and 30 days, and then the water extracts were used to determine the solubility and osteo-stimulatory effect of the glasses. Sr2+ doping retarded the dissolution rate of the glasses and the higher levels of Sr2+ doping (20 mol% and 25 mol%) promoted proliferation of osteoblasts. Except for Ly-B5 (containing 25 mol% SrO), discs of each glass powder exhibited bacteriostatic behavior against Staphylococcus aureus after 24 hours exposure. The glasses were enamelled onto Ti6Al4V substrates, and then bi-layer double cantilever beam (DCB) specimens were manufactured to measure the Mode I (GIC) and Mode II (GIIC) energy release rate of the glass coating/Ti6Al4V constructs. The mean GIC values increased from 6.56 ± 0.9 to 14.6 1 ± 2.1 J/m2 with increasing SrO content from Ly-B0 to Ly-B5, and the mean GIIC values increased from 36.07 ± 3.8 to 46.92 ± 3.3 J/m2 with increasing SrO content from Ly-B0 to Ly-B5, indicating that the incorporation of 15-25 mol% SrO significantly increased the fracture toughness of the construct. Moreover, the GIC and GIIC values of the coating/substrate system for all the six glasses significantly reduced (p ≤ 0.05) due to degradation in de-ionized water.

Isoelastic Cementless Total Hip Replacement in Rheumatoid Arthritis. Long-Term Results

1992 ◽  
Vol 2 (2) ◽  
pp. 43-46
Author(s):  
U. Fusco ◽  
R. Capelli ◽  
A. Avai ◽  
M. Gerundini ◽  
L. Colombini ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Hip Replacement ◽  
The Other ◽  
Long Term Results ◽  
X Rays ◽  
X Ray ◽  
The Mean ◽  
Cementless Total Hip Replacement

Between 1980 and 1987 we have implanted 46 isoelastic cementless THR in 40 patients affected with rheumatoid arthritis. We have reviewed 38 hips clinically and by X-ray. The mean follow-up was 8,5 years. Harris hip scores ranged from 30.6 preoperatively to 73,4 post-operatively when reviewed. While on the other hand Merle D'Aubigné hip scores ranged from 7,06 pre-operatively to 15,59 post-operatively. All patients have been satisfied, and X-rays showed an improvement for both Charnely and Gruen X-ray score.

scholarly journals Decreasing the Blood Transfusion Rate in Elective Hip Replacement Surgery Using an Autologous Drainage System

2007 ◽  
Vol 89 (2) ◽  
pp. 136-139 ◽  
Author(s):  
SW Sturdee ◽  
DJ Beard ◽  
G Nandhara ◽  
SV Sonanis
Keyword(s):  
Blood Transfusion ◽  
Hip Replacement ◽  
Drainage System ◽  
Length Of Hospital Stay ◽  
Transfusion Rate ◽  
Homologous Blood ◽  
Homologous Blood Transfusion ◽  
Drain Group ◽  
The Mean ◽  
Arthroplasty Surgery

INTRODUCTION This is a prospective study looking at the effectiveness of autologous postoperative drains in primary uncemented total hip replacement (THR) surgery. PATIENTS AND METHODS A total of 86 patients were studied, with 43 using standard suction drains (normal drain group) and 43 using autologous drains (autologous drain group). RESULTS Thirty-seven units of homologous blood were transfused in the normal drain group and 5 units in the autologous drain group. The mean number of units of homologous blood transfused per patient was reduced from 0.86 to 0.12 (P < 0.01) with the use of autologous drains and the transfusion rate was reduced from 23% to 6% (P < 0.02). The mean length of hospital stay was also reduced by two nights (P < 0.05). There were no adverse effects from using the autologous system and it does reduce the need for a homologous blood transfusion. CONCLUSIONS The system is simple and easy to use and we have also found it to be cost effective. Previously, it has not been reported as being effective in hip arthroplasty surgery, unlike knee arthroplasty surgery. We would recommend using autologous postoperative drains in primary THR surgery.

Heparin and Factor XaI Levels in Patients Undergoing Hip Surgery

1975 ◽  
Author(s):  
Duncan P. Thomas ◽  
S. Sagar ◽  
V. V. Kakkar
Keyword(s):  
Total Hip Replacement ◽  
Hip Replacement ◽  
Subsequent Development ◽  
Hip Surgery ◽  
Factor X ◽  
Preoperative Level ◽  
Total Hip ◽  
Vein Thrombosis ◽  
The Mean ◽  
Plasma Heparin

Plasma heparin and activated Factor X inhibitor (Xal) levels were measured in 25 patients undergoing total hip replacement. Blood samples were taken before, during and for 5 days after operation. In patients receiving heparin prophylaxis, over 50% of samples taken four hours after a subcutaneous injection of 5,000 units had no detectable plasma heparin; in none of the remaining samples did the level exceed 0.04 units per ml. In patients who developed deep vein thrombosis (DVT) postoperatively, as detected by 125-I-labelled fibrinogen and confirmed by venography, the mean preoperative level of Factor XaI was 73.5% (S. E. M.±6.9). In those patients who did not develop DVT, the mean preoperative level was 101.5% (S. E.M.±4.3) (P > 0.01).It is concluded that a regimen of 5,000 units 8-hour’ly does not give sustained plasma heparin levels after total hip replacement, which may in part explain the reduced effectiveness of low-dose heparin in preventing DVT in patients undergoing hip surgery. Low levels of Factor XaI in the immediate preoperative period correlated well with the subsequent development of thrombosis in these patients.

The Mayo Conservative hip: Experience from a District General Hospital

2009 ◽  
Vol 19 (3) ◽  
pp. 211-214 ◽  
Author(s):  
Rob E. Gilbert ◽  
Seema Salehi-Bird ◽  
Peter D. Gallacher ◽  
Phillip Shaylor
Keyword(s):  
Femoral Component ◽  
Hip Replacement ◽  
District General Hospital ◽  
Fracture Rate ◽  
Bone Stock ◽  
Femoral Prosthesis ◽  
Femoral Bone ◽  
Short Term ◽  
The Mean

The Mayo Conservative Hip femoral prosthesis has been designed to optimise proximal femoral loading as well as preserving proximal femoral bone stock. Between October 2003 and May 2006, 42 patients (49 hips) underwent total hip replacement (THR) using the Mayo Conservative Hip femoral component. The mean age at operation was 57.8 years (range 44 to 74) and the mean clinical follow up was 3.1 years (range 2.3 to 4.7 years). The aim of our study was to review the short term results of this unorthodox femoral component. We found that 18%° of stems were malaligned ≥ 5° and the prevalence of intra-operative femoral fracture was 4%. We feel this prosthesis is difficult to implant and has an unacceptable fracture rate.

scholarly journals Process optimized minimally invasive total hip replacement

2012 ◽  
Vol 3 (2) ◽  
pp. 3 ◽  
Author(s):  
Philipp Gebel ◽  
Markus Oszwald ◽  
Bernd Ishaque ◽  
Gaffar Ahmed ◽  
Recha Blessing ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Total Hip Replacement ◽  
Hip Replacement ◽  
Direct Anterior Approach ◽  
Operation Technique ◽  
Complication Rates ◽  
Leg Length ◽  
Total Hip ◽  
The Mean ◽  
Mean Time

The purpose of this study was to analyse a new concept of using the the minimally invasive direct anterior approach (DAA) in total hip replacement (THR) in combination with the leg positioner (Rotex- Table) and a modified retractor system (Condor). We evaluated retrospectively the first 100 primary THR operated with the new concept between 2009 and 2010, regarding operation data, radiological and clinical outcome (HOOS). All surgeries were perfomed in a standardized operation technique including navigation. The average age of the patients was 68 years (37 to 92 years), with a mean BMI of 26.5 (17 to 43). The mean time of surgery was 80 min. (55 to 130 min). The blood loss showed an average of 511.5 mL (200 to 1000 mL). No intra-operative complications occurred. The postoperative complication rate was 6%. The HOOS increased from 43 points pre-operatively to 90 (max 100 points) 3 months after surgery. The radiological analysis showed an average cup inclination of 43° and a leg length discrepancy in a range of +/- 5 mm in 99%. The presented technique led to excellent clinic results, showed low complication rates and allowed correct implant positions although manpower was saved.

The Effect of Sintering Temperature to the Quality of Hydroxyapatite Coating on Cobalt Alloys as the Candidate of Bone Implant Prosthesis

2017 ◽  
Vol 32 ◽  
pp. 59-68 ◽  
Author(s):  
Aminatun ◽  
Dyah Hikmawati ◽  
M. Yasin
Keyword(s):  
Aseptic Loosening ◽  
Hip Replacement ◽  
Sintering Temperature ◽  
Thick Layer ◽  
Sintering Process ◽  
Bone Implant ◽  
Ha Coating ◽  
Coating Method ◽  
Implant Prosthesis

Total hip replacement (THR) that is widely used today is the cemented type, which its application will lead to aseptic loosening. To avoid the occurrence of aseptic loosening, THR coated with hydroxyapatite (HA) is required because HA is osteoconductive which can stimulate the growth of osteoblasts. This study aims to determine the optimum sinter temperature which produce HA coating suitable as implant material. To achieve these objectives, the electrophoretic deposition (EPD) conducted coating method at concentrations of HA 1,0M, voltage of 100V for 30 minutes and then sintered at temperatures are 550°C, 700°C and 900°C respectively detention for 10 minutes. The results showed that the treatment of sintering after the coating process through the EPD method affect the characteristics of the layer thus formed. Sintering process affects the crystallinity of the HA layer. The higher the sintering temperature the higher its crystallinity. The higher the crystallinity the stronger the HA layer attached to the substrate cobalt alloy. Based on this research, the selected sintering temperature was 900 °C for 10 minutes which produced a layer of HA with the best characteristics that meet the standard of implant prosthesis, the crystallinity of 89.4%, thick layer of 70.80 ± 4.18 μm, adhesion strength of 21.87 ± 0.23 MPa, the corrosion rate of 0.025 mpy and 70.3% cell viability.

scholarly journals Total hip arthroplasty in patients with slipped capital femoral epiphysis: a systematic analysis of 915 cases

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
Eustathios Kenanidis ◽  
Panagiotis Kakoulidis ◽  
Sousana Panagiotidou ◽  
Andreas Leonidou ◽  
Panagiotis Lepetsos ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Hip Replacement ◽  
Functional Outcomes ◽  
Slipped Capital Femoral Epiphysis ◽  
Cochrane Library ◽  
Systematic Analysis ◽  
Total Hip ◽  
Ovid Medline ◽  
The Mean

There is limited evidence on the outcomes of Total Hip Arthroplasty (THA) in Slipped Capital Femoral Epiphysis (SCFE) patients. This systematic review aims to evaluate the current literature in terms of survival rate, functional outcomes, complications and types of implants of THA in SCFE patients. Following the established methodology of PRISMA guidelines, PubMed, Cochrane library, ScienceDirect and Ovid MEDLINE were systematically searched from inception to September 2018. The search criteria used were: (“total hip arthroplasty’’ OR ‘’total hip replacement’’ OR “hip arthroplasty’’ OR ‘’hip replacement’’) AND (‘’slipped capital femoral epiphysis’’ OR ‘’slipped upper femoral epiphysis’’ OR ‘’femoral epiphysis’’). Ten studies were finally included in the analysis and were qualitatively appraised using the Newcastle-Ottawa tool. Variables were reported differently between studies. The sample size varied from 12 to 374 THAs. A total of 877 patients undergone 915 THAs. The mean reported follow-up ranged from 4.4 to 15.2 years and the mean patients’ age at the time of THA from 26 to 50 years. Four studies specified the type of implants used, with 62% being uncemented, 24% hybrid (uncemented cup/cemented stem) and 14% cemented. All but three studies reported the mean survival of implants that ranged from 64.9% to 94.8%. A limited number of complications were mentioned. There was a tendency for more favorable functional outcomes in modern studies. Modern THA-studies in SCFE patients showed improvement of survivorship, clinical outcomes and patient satisfaction. Future higher-quality studies are necessary to estimate long-term postoperative outcomes better.

Sol–gel derived SiO2–B2O3–Na2O–ZnO–Al2O3 glass powder for glass-based composite

2019 ◽  
Vol 34 (04) ◽  
pp. 2050052
Author(s):  
Changxiu Wen ◽  
Xiaoxia Cui ◽  
Yantao Xu ◽  
Pengxiang Yang ◽  
Xiaozhang Wang ◽  
...  
Keyword(s):  
Glass Powder ◽  
Coefficient Of Thermal Expansion ◽  
Sol Gel ◽  
Glass Network ◽  
Treatment Temperature ◽  
Synthesis Conditions ◽  
Surface Areas ◽  
Ft Ir ◽  
The Fourier Transform ◽  
Gel Glasses

The glass powder with a relatively complicated composition of 64.02SiO2–10.05B2O3–7.84Na2O–14.07ZnO–4.02Al2O3 (in wt.%) was first synthesized via sol–gel route. The optimal synthesis conditions for the amorphous gel are obtained. The glass transition temperature [Formula: see text] of xerogel was detected as 552[Formula: see text]C and the glass network structure formed by the [SiO4], [BO4] and [AlO4] units were confirmed by the Fourier Transform-Infrared Spectroscopy (FT-IR). The phase structure and morphologies of glass powder were characterized by X-ray diffractometer (XRD) and Field Emission-Scanning Electron Microscope (FE-SEM), the xerogels and sol–gel glasses exhibit amorphous phase when the heat-treatment temperature increases from [Formula: see text]C to [Formula: see text]C. The prepared glass powder with high specific surface areas and a large amount of pores contribute to the synthesis of a composite of glass-mullite-[Formula: see text]-eucryptite at a relatively low sintering temperature of [Formula: see text]C, which present a relatively low coefficient of thermal expansion (CTE) and high mechanical strength.

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