The Effect of Genders on the Perception of the Combined Effect of Local Discomfort Parameters

If the draught and the radiant thermal asymmetry caused by the warm ceiling appear simultaneously, will women and men be affected in the same way? This research aims to answer this question, by clarifying the understanding of the joint mechanism of action of the two local discomfort factors with the help of instrumental and human subject measurements. The most important result of the present research is identifying that if PPD < 6%, radiant thermal asymmetry varies in the range of 5–15 °C and the draught rate DR = 15% or DR = 25%, then at a given range of the interval men are significantly more dissatisfied with warm ceilings than women; women’s AMV votes are significantly lower than men's; In the case of DR = 15%, the work accuracy of women is significantly higher, while in the case of men, the work accuracy is higher at DR = 25%.

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Combined effect of Thymus capitatus and Cinnamomum verum essential oils with conventional drugs against Candida albicans biofilm formation and elucidation of the molecular mechanism of action

Industrial Crops and Products ◽

10.1016/j.indcrop.2019.111720 ◽

2019 ◽

Vol 140 ◽

pp. 111720 ◽

Cited By ~ 2

Author(s):

Rym Essid ◽

Dorra Gharbi ◽

Ghassen Abid ◽

Ines Karkouch ◽

Thouraya Ben Hamouda ◽

...

Keyword(s):

Candida Albicans ◽

Essential Oils ◽

Molecular Mechanism ◽

Mechanism Of Action ◽

Biofilm Formation ◽

Combined Effect ◽

Thymus Capitatus ◽

Molecular Mechanism Of Action

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Analysis of the combined effect of two linear inhibitors on a single enzyme

Biochemical Journal ◽

10.1042/bj3290689 ◽

1998 ◽

Vol 329 (3) ◽

pp. 689-698 ◽

Cited By ~ 36

Author(s):

Juan J. MARTINEZ-IRUJO ◽

María L. VILLAHERMOSA ◽

Javier MERCAPIDE ◽

Jesús F. CABODEVILLA ◽

Esteban SANTIAGO

Keyword(s):

Experimental Data ◽

Mechanism Of Action ◽

Combined Effect ◽

Isobolographic Analysis ◽

Alternative Representation ◽

Common Mistake ◽

Inhibition Constants ◽

Individual Use ◽

Single Enzyme

Different methods for studying the concurrent effects of two linear inhibitors on a single enzyme have been published, including the fractional product of Webb, the Yonetani-Theorell plot or the method of Chou and Talalay. Recently the use of combination plots has also been advocated for this purpose. We have evaluated the applicability of these methods and found that most of them depend on assumptions about the mechanism of action of the inhibitors. If the mechanism of action is not completely understood, or if some assumptions about the mechanism are unfounded, the parameters obtained may be meaningless. Even if these assumptions are correct, the interaction can be advantageously measured using an alternative representation that does not require a knowledge of the inhibition constants and allows experimental data to be retrieved from the plot. In other cases it is the interpretation of the results rather than the validity of the method that is misleading. A common mistake is to take the exclusivity of the effects of two inhibitors as exclusivity of their binding. We show that this assumption is seldom justified. In any case, it is possible to decide whether the combination of two or more inhibitors is more effective than their individual use by means of isobolographic analysis, even when no information about their mechanism of action is available.

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Response of seated human subject to ship structure motion caused by the combined effect of shock wave and bubble pulsation

Journal of Biomechanics ◽

10.1016/j.jbiomech.2021.110666 ◽

2021 ◽

pp. 110666

Author(s):

Yongbo Jiang ◽

Xiaofei Cao ◽

Yongzhen Wang ◽

Cheng Wu ◽

Ying Li

Keyword(s):

Shock Wave ◽

Human Subject ◽

Combined Effect ◽

Ship Structure ◽

Bubble Pulsation

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A New Method to Describe the Combined Effect of Draught and Radiant Thermal Asymmetry on Human Work Performance

Slovak Journal of Civil Engineering ◽

10.2478/sjce-2020-0014 ◽

2020 ◽

Vol 28 (2) ◽

pp. 43-49

Author(s):

Balázs András-Tövissi ◽

László Kajtár

Keyword(s):

Human Resources ◽

Thermal Comfort ◽

Human Subject ◽

Work Performance ◽

Joint Effect ◽

Combined Effect ◽

New Method ◽

Work Efficiency ◽

Crucial Importance ◽

Thermal Environments

AbstractHuman resources are the most important elements of economic units; thus, the efficiency of human work is of crucial importance. Work efficiency can be achieved only in an environment offering optimal thermal comfort. The present study makes use of human subject experiments in order to investigate the joint effect of draughts and warm ceilings on work performance. During the experiments, 10 thermal environments with 5 radiant thermal asymmetries and 2 draught rates were investigated. The most important outcome of the research is the presentation of the combined effect of a draught and a warm ceiling on work performance.

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A new method for evaluating the joint effect of draught and the hot ceiling

Thermal Science ◽

10.2298/tsci191211102a ◽

2020 ◽

pp. 102-102

Author(s):

Balázs András-Tövissi ◽

László Kajtár ◽

József Nyers

Keyword(s):

Mechanical Ventilation ◽

Thermal Comfort ◽

Mathematical Description ◽

Human Subject ◽

Thermal Sensation ◽

Joint Effect ◽

Combined Effect ◽

New Method ◽

Random Combination

For buildings with ceiling heating and mechanical ventilation, it is extremely important to know the combined effect of the draught and the radiant thermal asymmetry caused by a warm ceiling. There is plenty of literature offering separate descriptions of the dissatisfaction caused by draught and warm ceilings, but research on the combined effect of these two local discomfort factors is incomplete. In order to fill in this gap, human subject measurements were conducted involving 20 subjects, 10 men and 10 women, who were asked to complete questionnaires on thermal sensation, while being exposed to a random combination of 5 asymmetries and 2 draughts. Analyzing the results obtained this way made it possible to evaluate the combined effect of the draught and radiant thermal asymmetry on thermal comfort. The most important outcome of the research is the mathematical description of the expected dissatisfaction rate and the presentation of the differences depending on gender.

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