scholarly journals Using state-of-the-art DNA sequencing technology to reveal the bacteria present in Irish artisanal cheese

2011 ◽  
pp. 187-192
Author(s):  
Lisa Quigley
Keyword(s):  
Dna Sequencing ◽  
State Of The Art ◽  
Sequencing Technology

scholarly journals Current and Future Methodology for Quantitation and Site-specific Mapping the Location of DNA Adducts

2021 ◽  
Author(s):  
Gunnar Boysen ◽  
Intawat Nookaew
Keyword(s):  
Dna Sequencing ◽  
Dna Adducts ◽  
Single Molecule ◽  
State Of The Art ◽  
Dna Adduct ◽  
Sequencing Technology ◽  
Specific Mass ◽  
Comprehensive Picture ◽  
Specific Mapping ◽  
Altered Gene

Abstract: Formation of DNA adducts is a key event for a genotoxic mode of action and its formation is often use as surrogate for mutation and cancer. Interest in DNA adducts are twofold, first, to demonstrate exposure, and second, to link DNA adduct location to subsequent mutations or altered gene regulation. High chemically specific mass spectrometry methods have been established for DNA adduct quantitation and elegant bio-analytic methods utilizing enzymes, various chemistries, and molecular biology methods to visualize the location of DNA adducts. Traditionally, these highly specific methods cannot be combined, and the results are incomparable. Initially developed for single-molecule DNA sequencing, nanopore-type technologies are expected to enable simultaneous quantitation and location of DNA adducts across the genome. We will briefly summarize the current methodologies for state-of-the-art quantitation of DNA adduct levels and mapping of DNA adducts and describe novel single-molecule DNA sequencing technology that is expected to achieve both measures simultaneously. Emerging technologies are expected to soon provide a comprehensive picture of the exposome and identify gene regions susceptible to DNA adduct formation.

Universal base analogues and their applications in DNA sequencing technology

RSC Advances ◽  
2013 ◽  
Vol 3 (35) ◽  
pp. 14910 ◽  
Author(s):  
Feng Liang ◽  
Ying-Zhu Liu ◽  
Peiming Zhang
Keyword(s):  
Dna Sequencing ◽  
Sequencing Technology

Evaluation of genetic diversity of Chinese Pleurotus ostreatus cultivars using DNA sequencing technology

2012 ◽  
Vol 63 (2) ◽  
pp. 571-576 ◽  
Author(s):  
Yu Liu ◽  
Shouxian Wang ◽  
Yonggang Yin ◽  
Feng Xu
Keyword(s):  
Genetic Diversity ◽  
Dna Sequencing ◽  
Pleurotus Ostreatus ◽  
Sequencing Technology

Single molecule DNA sequencing in submicrometer channels: state of the art and future prospects

2001 ◽  
Vol 86 (3) ◽  
pp. 181-201 ◽  
Author(s):  
M. Sauer ◽  
B. Angerer ◽  
W. Ankenbauer ◽  
Z. Földes-Papp ◽  
F. Göbel ◽  
...  
Keyword(s):  
Dna Sequencing ◽  
Single Molecule ◽  
State Of The Art ◽  
Future Prospects

scholarly journals Omics and bioinformatics approaches to target boar taint

2016 ◽  
Author(s):  
Rahul Agarwal ◽  
Jitendra Narayan
Keyword(s):  
Reference Genome ◽  
State Of The Art ◽  
Boar Taint ◽  
Omics Data ◽  
Pork Meat ◽  
Sequencing Technology ◽  
Animal Products ◽  
Livestock Species ◽  
Genome Wide ◽  
Young Boars

AbstractIn livestock species, a rapid growth in high-throughput omics data has accelerated the pace of studies that target to dissect economically important traits to provide better quality animal products to consumers. In pig industries, young boars are generally castrated to remove boar taint, a phenotypic and inheritable trait well-known by an abnormally bad smell and taste in pork meat derived from some uncastrated male pigs. Existence of porcine reference genome made possible to catalogue genome-wide QTLs, candidate genes and biomarkers in associations with boar taint and other industrially significant traits in pigs. The aim of this paper to review the contribution of bioinformatics resources and omics technology in boar taint related studies. This paper also provides concise details about state-of-the-art sequencing technology.

Cyanobacterial biodiversity of semiarid public drinking water supply reservoirs assessed via next-generation DNA sequencing technology

2019 ◽  
Vol 57 (6) ◽  
pp. 450-460 ◽  
Author(s):  
Adriana Sturion Lorenzi ◽  
Mathias Ahii Chia ◽  
Fabyano Alvares Cardoso Lopes ◽  
Genivaldo Gueiros Z. Silva ◽  
Robert A. Edwards ◽  
...  
Keyword(s):  
Drinking Water ◽  
Water Supply ◽  
Dna Sequencing ◽  
Drinking Water Supply ◽  
Next Generation ◽  
Sequencing Technology ◽  
Next Generation Dna Sequencing ◽  
Public Drinking Water ◽  
Public Drinking ◽  
Water Supply Reservoirs

scholarly journals Cultivating DNA Sequencing Technology After the Human Genome Project

2020 ◽  
Vol 21 (1) ◽  
pp. 117-138
Author(s):  
Jeffery A. Schloss ◽  
Richard A. Gibbs ◽  
Vinod B. Makhijani ◽  
Andre Marziali
Keyword(s):  
Dna Sequencing ◽  
Human Genome ◽  
Human Genome Project ◽  
Technology Development ◽  
Genome Project ◽  
Alternative Methods ◽  
Biological Research ◽  
Sequencing Technology ◽  
Core Technology ◽  
The Human Genome Project

When the Human Genome Project was completed in 2003, automated Sanger DNA sequencing with fluorescent dye labels was the dominant technology. Several nascent alternative methods based on older ideas that had not been fully developed were the focus of technical researchers and companies. Funding agencies recognized the dynamic nature of technology development and that, beyond the Human Genome Project, there were growing opportunities to deploy DNA sequencing in biological research. Consequently, the National Human Genome Research Institute of the National Institutes of Health created a program—widely known as the Advanced Sequencing Technology Program—that stimulated all stages of development of new DNA sequencing methods, from innovation to advanced manufacturing and production testing, with the goal of reducing the cost of sequencing a human genome first to $100,000 and then to $1,000. The events of this period provide a powerful example of how judicious funding of academic and commercial partners can rapidly advance core technology developments that lead to profound advances across the scientific landscape.

The current approaches to the study of algae: DNA barcoding and DNA taxonomy

2021 ◽  
pp. 124-130
Author(s):  
Anna D. Temraleeva ◽  
Elena S. Krivina ◽  
Yury S. Bukin
Keyword(s):  
Phylogenetic Analysis ◽  
Dna Sequencing ◽  
Dna Barcoding ◽  
Species Identification ◽  
Green Algae ◽  
Molecular Genetic ◽  
Algal Species ◽  
Species Boundaries ◽  
Sequencing Technology ◽  
Dna Taxonomy

The understanding of the impossibility of distinguishing algal species based on morphological features came with the development of DNA sequencing technology, which today is a necessary tool for defining species boundaries and testing traditional species concepts. The paper discusses popular approaches to species identification (DNA barcoding) and the description of new and revision of known species (DNA taxonomy) using molecular genetic methods. The requirements and limitations in their work are given, as well as examples of phylogenetic analysis of green algae from the clade Moewusinia and Parachlorella, including the genus Micractinium.

Abstract 4243: Genetic variants frequently detected in Egyptian breast cancer tumors: Comprehensive cancer panel by ion torrent DNA sequencing technology

2019 ◽  
Author(s):  
Abdel-Rahman N. Zekri ◽  
Osman Mansour ◽  
Samah A. Loutfy ◽  
Mohamed M. Hafez ◽  
M. Gomaa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Sequencing ◽  
Genetic Variants ◽  
Ion Torrent ◽  
Sequencing Technology ◽  
Cancer Panel
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