Spatial regularities between non-immigrant and immigrant numbers in Canada

2014 ◽  
Vol 11 (1) ◽  
pp. 90-100
Author(s):  
Yigit Aydede
Keyword(s):  
Fixed Effects ◽  
Spatial Scales ◽  
National Scale ◽  
Pooled Data

The present study intends to reveal spatial regularities between non-immigrant and immigrant numbers in two different ways. First, it questions the existence of those regularities when spatial scales get finer. Second, it uses pooled data over four population censuses covering the period from 1991 to 2006, which enabled us to apply appropriate techniques to remove those unobserved fixed effects so that the estimations would accurately identify the linkage between local immigrant and non-immigrant numbers. The results provide evidence about the existence of negative spatial regularities between non-immigrant and immigrant numbers in Canada at national scale.

European Geography

2004 ◽  
Author(s):  
Boian Koulov ◽  
Linda McCarthy
Keyword(s):  
European Integration ◽  
Spatial Scales ◽  
Economic Life ◽  
Environmental Damage ◽  
Eastern European ◽  
Political Transformation ◽  
National Scale ◽  
European Continent ◽  
And Migration ◽  
The Cold War

The European Specialty Group (ESG) was founded with considerable enthusiasm in 1992. Its organization and the rapid membership increase were in response to the historic changes following the fall of the Iron Curtain, the reintegration of the European continent, and a heightened interest in the evolution of European political and economic life. The purpose of the ESG is to move beyond the Cold War legacy of East–West division of the continent and foster research, teaching, and scholarly interaction on the geography of the new Europe. The ESG also serves as a bridge between US geographers working on Europe and their counterparts in the rest of the world. Finally, the group promotes the study of Europe within the discipline of geography and facilitates the exchange of information and ideas among its members and Europeanists in other disciplines, government, and private agencies. Research on Europe has been undertaken at a variety of spatial scales. A number of books reflect the pan-European scale (Berentsen 1993, 1997; Harris 1991, 1993a, b, 1997; Jordan 1996; McDonald 1997; Murphy 1991; Unwin 1998). The national scale also has received attention due to the continued importance of the different national contexts despite increased European integration, in conjunction with difficulties created by the lack of comparable statistical databases at a sub-national scale for the countries across Europe. Regardless of spatial scale several consistent themes have emerged. Within political geography focus is clearly on the new divisions of Europe, states–nations relationships, sub-national political transformation, the twin forces of democratization and nationalism, and ethnic conflict. Within economic geography research has centered around issues of “widening” versus “deepening” in the EU, globalization and pan-European integration, the impacts and implications of the incorporation of Central and Eastern European nations into the European economy, and the spatially uneven nature of economic change. Geographers also have been active in addressing issues of environmental damage, population, and migration. This chapter takes a regional approach that reflects the typical focus of most research. The material is treated systematically within sections on Western, Nordic, Eastern, and Mediterranean Europe.

Geographies of Climate Change Belief

2017 ◽  
Author(s):  
Debbie Hopkins ◽  
Ezra M. Markowitz
Keyword(s):  
Climate Change ◽  
Climate Policy ◽  
Risk Perceptions ◽  
Spatial Scales ◽  
Public Perceptions ◽  
Data Sets ◽  
National Scale ◽  
Large Variability ◽  
Change Perceptions ◽  
Nationally Representative

Despite scientific consensus on the anthropogenic causation of climate change, and ever-growing knowledge on the biophysical impacts of climate change, there is large variability in public perceptions of and belief in climate change. Public support for national and international climate policy has a strong positive association with certainty that climate change is occurring, human caused, serious, and solvable. Thus to achieve greater acceptance of national climate policy and international agreements, it is important to raise public belief in climate change and understandings of personal climate risk. Public understandings of climate change and associated risk perceptions have received significant academic attention. This research has been conducted across a range of spatial scales, with particular attention on large-scale, nationally representative surveys to gain insights into country-scale perceptions of climate change. Generalizability of nationally representative surveys allows some degree of national comparison; however, the ability to conduct such comparisons has been limited by the availability of comparative data sets. Consequently, empirical insights have been geographically biased toward Europe and North America, with less understanding of public perceptions of climate change in other geographical settings including the Global South. Moreover, a focus on quantitative surveying techniques can overlook the more nuanced, culturally determined factors that contribute to the construction of climate change perceptions. The physical and human geographies of climate change are diverse. This is due to the complex spatial dimensions of climate change and includes both the observed and anticipated geographical differentiation in risks, impacts, and vulnerabilities. While country location and national climate can impact upon how climate change is understood, so too will sociocultural factors such as national identity and culture(s). Studies have reported high variability in climate change perceptions, the result of a complex interplay between personal experiences of climate, social norms, and worldviews. Exploring the development of national-scale analyses and their findings over time, and the comparability of national data sets, may provide some insights into the factors that influence public perceptions of climate change and identify national-scale interventions and communications to raise risk perception and understanding of climate change.

The Pharmacokinetics Of Turoctocog Alfa Are Consistent Over Different Concentrations and Production Lots

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 4783-4783 ◽  
Author(s):  
Víctor Jiménez-Yuste ◽  
Sandra Lejniece ◽  
Robert Klamroth ◽  
Trine Saugstrup ◽  
Judi Moss
Keyword(s):  
Half Life ◽  
Research Funding ◽  
Fixed Effects ◽  
Hemophilia A ◽  
Severe Hemophilia ◽  
Pooled Data ◽  
One Stage ◽  
Chromogenic Assay ◽  
The One ◽  
Pharmacokinetic Difference

Introduction Turoctocog alfa is a B domain truncated human recombinant FVIII for treatment of patients with hemophilia A. The production yields a highly homogenous product with the same tyrosine sulphation as human FVIII. In order to confirm the consistency of turoctocog alfa pharmacokinetics (PK) over different production lots and vial strengths, a clinical trial was performed in 15 patients with severe hemophilia A. Aim To compare the PK of 3 lots of 2000 IU/vial and 1 lot of 3000 IU/vial of turoctocog alfa after i.v. administration of 50 IU/kg in patients with severe haemophilia A. Methods This was a multi-centre, open-label trial investigating the PK of 4 lots of turoctocog alfa (3 lots of 2000 IU/vial; Lots A, B and C, and 1 lot of 3000 IU/vial; Lot D) in patients with severe hemophilia A (FVIII<1%). The trial was performed as a two-period, incomplete block, cross-over trial, in which each patient was allocated at random to a predefined sequence of 2 different lots of turoctocog alfa. The FVIII activity was assessed using both the one-stage clot and chromogenic assays. Both the primary endpoint, normalized AUC (AUC*(planned dose/actual dose)), and the secondary PK endpoints were analyzed by ANCOVA on the log transformed values, with lot, visit and patient as fixed effects. Each of the three 2000 IU/vial lots was compared and tested against the 2 other 2000 IU/vial lots. If not significantly different on a 5% level, the 3 lots were pooled together and tested against the 3000 IU/vial lot. Results Fifteen patients with a mean age of 38.6 years (ranging from 21 to 60 years) were included from 3 hemophilia centres in 3 different countries. Three adverse events (AEs) were reported in the trial by 2 separate patients; all AEs were judged to be unlikely related to the trial product. There was no development of inhibitors. There was no pharmacokinetic difference observed between Lots A, B, C (2000 IU/vials) and there was no pharmacokinetic difference observed between the pooled data from lot A, B and C (2000 IU/vial) and lot D (3000 IU/vial) based on normalized AUC, half-life, incremental recovery and clearance. The estimated mean values (with 90% CI) for the PK parameters based on the chromogenic assay are presented in Table 1. The results were similar for the one-stage clot assay and the chromogenic assay. Conclusions No pharmacokinetic differences were observed between the three 2000 IU/vial lots (Lot A, Lot B and Lot C), nor were there pharmacokinetic differences between Lot D (3000 IU/vial) and pooled data from Lots A, B and C, based on normalized AUC, half-life, incremental recovery and clearance. There were no safety concerns and no inhibitor development in the trial. Disclosures: Jiménez-Yuste: Novo Nordisk: Consultancy, Research Funding, Speakers Bureau. Klamroth:Novo Nordisk, CSL Behring, Bayer, Baxter, Pfizer: Honoraria, Research Funding. Saugstrup:Novo Nordisk: Employment. Moss:Novo Nordisk: Employment.

scholarly journals National-scale changes in crop diversity through the Anthropocene

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rachel O. Mariani ◽  
Marc W. Cadotte ◽  
Marney E. Isaac ◽  
Denis Vile ◽  
Cyrille Violle ◽  
...  
Keyword(s):  
Environmental Change ◽  
Spatial Scales ◽  
Crop Diversity ◽  
Production Data ◽  
Economic Stability ◽  
National Scale ◽  
Country Level ◽  
Context Dependent ◽  
Ecological Functioning

AbstractExpansion of crops beyond their centres of domestication is a defining feature of the Anthropocene Epoch. This process has fundamentally altered the diversity of croplands, with likely consequences for the ecological functioning and socio-economic stability of agriculture under environmental change. While changes in crop diversity through the Anthropocene have been quantified at large spatial scales, the patterns, drivers, and consequences of change in crop diversity and biogeography at national-scales remains less explored. We use production data on 339 crops, grown in over 150 countries from 1961 to 2017, to quantify changes in country-level crop richness and evenness. Virtually all countries globally have experienced significant increases in crop richness since 1961, with the early 1980s marking a clear onset of a ~ 9-year period of increase in crop richness in countries worldwide. While these changes have increased the similarity of diversity of croplands among countries, only half of countries experienced increases in crop evenness through time. Ubiquitous increases in crop richness within nearly all countries between 1980 and 2000 are a unique biogeographical feature of the Anthropocene. At the same time, we detected opposing changes in crop evenness, and only modest signatures of increased homogenization of croplands among countries. Therefore context-dependent and, at least, national-scale assessments are needed to understand and predict how changes in crop diversity influence agricultural resistance and resilience to environmental change.

scholarly journals Effect of wind turbines on bird abundance: A national scale analysis based on fixed effects models

Energy Policy ◽  
2019 ◽  
Vol 132 ◽  
pp. 357-366 ◽  
Author(s):  
Ruiqing Miao ◽  
Prasenjit N. Ghosh ◽  
Madhu Khanna ◽  
Weiwei Wang ◽  
Jian Rong
Keyword(s):  
Wind Turbines ◽  
Fixed Effects ◽  
Scale Analysis ◽  
National Scale ◽  
Bird Abundance ◽  
Fixed Effects Models

scholarly journals Constraining sector-specific CO<sub>2</sub> and CH<sub>4</sub> emissions in the US

2017 ◽  
Vol 17 (6) ◽  
pp. 3963-3985 ◽  
Author(s):  
Scot M. Miller ◽  
Anna M. Michalak
Keyword(s):  
Co2 Emissions ◽  
Spatial Scales ◽  
Demographic Data ◽  
Anthropogenic Source ◽  
Emission Inventories ◽  
Top Down ◽  
National Scale ◽  
Activity Data ◽  
Ch4 Emissions ◽  
The Us

Abstract. This review paper explores recent efforts to estimate state- and national-scale carbon dioxide (CO2) and methane (CH4) emissions from individual anthropogenic source sectors in the US. Nearly all state and national climate change regulations in the US target specific source sectors, and detailed monitoring of individual sectors presents a greater challenge than monitoring total emissions. We particularly focus on opportunities to synthesize disparate types of information on emissions, including emission inventory data and atmospheric greenhouse gas data.We find that inventory estimates of sector-specific CO2 emissions are sufficiently accurate for policy evaluation at the national scale but that uncertainties increase at state and local levels. CH4 emission inventories are highly uncertain for all source sectors at all spatial scales, in part because of the complex, spatially variable relationships between economic activity and CH4 emissions. In contrast to inventory estimates, top-down estimates use measurements of atmospheric mixing ratios to infer emissions at the surface; thus far, these efforts have had some success identifying urban CO2 emissions and have successfully identified sector-specific CH4 emissions in several opportunistic cases. We also describe a number of forward-looking opportunities that would aid efforts to estimate sector-specific emissions: fully combine existing top-down datasets, expand intensive aircraft measurement campaigns and measurements of secondary tracers, and improve the economic and demographic data (e.g., activity data) that drive emission inventories. These steps would better synthesize inventory and top-down data to support sector-specific emission reduction policies.

scholarly journals Identifying Potential Cropland Losses When Conserving 30% and 50% Earth with Different Approaches and Spatial Scales

Land ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 704
Author(s):  
Jianqiao Zhao ◽  
Yue Cao ◽  
Le Yu ◽  
Xiaoxuan Liu ◽  
Yichuan Shi ◽  
...  
Keyword(s):  
Sustainable Development ◽  
Biodiversity Conservation ◽  
Mass Extinction ◽  
Spatial Scales ◽  
Global Scale ◽  
National Scale ◽  
Conservation Targets ◽  
The Earth ◽  
Sustainable Future

Biodiversity conservation is the cornerstone for sustainable development. Bold conservation targets provide the last opportunities to halt the human-driven mass extinction. Recently, bold conservation targets have been proposed to protect 30% or 50% of Earth. However, little is known about its potential impacts on cropland. We identify potential cropland losses when 30% and 50% of global terrestrial area is given back to nature by 2030/2050, at three spatial scales (global, biome and country) and using two approaches (“nature-only landscapes” and “shared landscapes”). We find that different targets, applied scales and approaches will lead to different cropland losses: (1) At the global scale, it is possible to protect 50% of the Earth while having minimum cropland losses. (2) At biome scale, 0.64% and 8.54% cropland will be lost globally in 2030 and 2050 under the nature-only approach while by contrast, the shared approach substantially reduces the number of countries confronted by cropland losses, demanding only 0% and 2.59% of global cropland losses in 2030 and 2050. (3) At the national scale, the nature-only approach causes losses of 3.58% and 10.73% of global cropland in 2030 and 2050, while the shared approach requires 0.77% and 7.55% cropland in 2030 and 2050. Our results indicate that bold conservation targets could be considered, especially when adopting the shared approach, and we suggest adopting ambitious targets (protecting at least 30% by 2030) at the UN Biodiversity Conference (COP 15) to ensure a sustainable future for Earth.

scholarly journals National-scale Changes in Crop Diversity Through the Anthropocene

2021 ◽  
Author(s):  
Rachel O. Mariani ◽  
Marc W. Cadotte ◽  
Marney E. Isaac ◽  
Denis Vile ◽  
Cyrille Violle ◽  
...  
Keyword(s):  
Spatial Scales ◽  
Crop Diversity ◽  
Production Data ◽  
National Scale ◽  
Country Level ◽  
Context Dependent

Abstract Expansion of crops beyond their centres of domestication is a defining feature of the current Anthropocene Epoch. These patterns have been quantified at large spatial scales, but the drivers and consequences of change in crop diversity and biogeography at national-scales remains less explored. We use production data on 339 crops, grown in over 150 countries from 1961–2017, to quantify changes in country-level crop richness and evenness. Virtually all countries globally have experienced significant increases in crop richness since 1961, with the early 1980s marking a clear onset of a ~ 9 year period of increase in crop richness worldwide. While these changes have increased the similarity of diversity of croplands among countries, only half of countries experienced increases in crop evenness through time. Ubiquitous increases in crop richness within nearly all countries between 1980–2000 are a unique biogeographical feature of the Anthropocene. At the same time, opposite changes in crop evenness, and only modest signatures of increased homogenization of croplands among countries, underscores that the understanding or predicting of consequences of crop diversity change requires context-dependent and, at least, national-scale assessments.

scholarly journals Burdened by renewable energy? A multi-scalar analysis of distributional justice and wind energy in the United States

2019 ◽  
Author(s):  
Tom Mueller ◽  
Matthew M Brooks
Keyword(s):  
United States ◽  
Land Use ◽  
Renewable Energy ◽  
Wind Energy ◽  
Fixed Effects ◽  
Spatial Scales ◽  
The United States ◽  
Energy Development ◽  
Energy Infrastructure ◽  
Wind Energy Development

The transition towards renewable energy is likely to be uneven across social and spatial dimensions. To ensure this transition is equitable and just, energy injustice has become the key framework for analyzing and interpreting the distribution of energy infrastructure. Wind energy development has experienced a significant gap between broad public support for increased development but persistent localized opposition to proposed projects, indicating that wind represents a locally unwanted land use. We argue that although the negative impacts of wind energy infrastructure are less extreme than those posed by other, more toxic, unwanted land uses, their status as a locally unwanted land use will produce similar distributional injustices as have been found throughout the environmental injustice literature. Using data from both the American Community Survey and the U.S. Wind Turbine Database, we use logistic and Poisson regressions, fixed effects, and temporal lags to evaluate the current landscape of wind energy injustice along the social dimensions of income, race and ethnicity, age, education, labor force participation, and rurality at three spatial scales: between all counties within the contiguous United States, between counties within states with wind energy, and between census tracts within counties with wind energy. We find results vary by scale and whether the model is comparing the presence of any development or the size of that development. The most evidence of injustice is visible at the within-county level related to whether or not there is any wind energy development, with few relationships present when evaluating the absolute size of development.

A Meta-Analysis for Association of ACE I/D Polymorphism with Susceptibility to Preterm Birth

2021 ◽  
Author(s):  
Reza Bahrami ◽  
Seyed Alireza Dastgheib ◽  
Hossein Golestanpour ◽  
Elahe Akbarian ◽  
Alireza Emarati ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Recessive Model ◽  
Biomedical Literature ◽  
Case Control Studies ◽  
China National Knowledge Infrastructure ◽  
Pooled Data ◽  
Increased Risk ◽  
Study Heterogeneity

Background: Preterm birth is one of the main contributors to newborn mortality, morbidity, and hospitalization in the first year of life globally. To date, several numbers of studies have reported that Angiotensin-Converting enzyme Insertion/Deletion polymorphism (ACE I/D) is linked with preterm birth. But those results are conflicting. Thus, we carried out this meta-analysis to summarize the existing data and evaluated the association. Methods: All eligible studies were collected from PubMed, Scopus, SciELO, MedRxiv, SID, China National Knowledge Infrastructure (CNKI), and Chinese Biomedical Literature Database (CBLD) up to 01 March 2021. The pooled odds ratios (ORs) and 95% confidence interval (CIs) under all five genetic models were calculated using either random-effects or fixed-effects models dependent on study heterogeneity. Results: A total of five case-control studies with 480 preterm birth cases and 702 healthy subjects were included. Pooled data showed that the ACE I/D polymorphism was significantly associated with increased risk of preterm birth under the allele model (I vs. D: OR = 1.219, 95% CI 1.023-1.453, P = 0.027), homozygote model (II vs. DD: OR = 0.662, 95% CI 1.149-2.385, P = 0.007), and recessive model (DD vs. DI+II: OR = 0.707, 95% CI 1.082-1.948, P = 0.013). Stratified analysis by ethnicity indicated that the ACE I/D polymorphism was significantly associated with preterm birth in Caucasian descendants. Conclusion: Our pooled data revealed that ACE I/D polymorphism is associated with the risk of preterm birth. However, larger and more rigorous studies among different populations are needed to evaluate the association with preterm birth.

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