scholarly journals Status of Serum Calcium and Magnesium in Women Taking Oral Contraceptive

2018 ◽  
Vol 10 (2) ◽  
pp. 64-68
Author(s):  
F Hasanat ◽  
PK Chakroborty ◽  
DN Nahar ◽  
S Bishwash ◽  
KN Hena ◽  
...  
Keyword(s):  
Oral Contraceptive ◽  
Serum Calcium ◽  
Serum Magnesium ◽  
Oral Contraceptive Pill ◽  
Oral Contraceptive User ◽  
Contraceptive User ◽  
Significant Difference ◽  
The Status ◽  
Human Need ◽  
Calcium And Magnesium

The oral contraceptive pill fulfills the great human need for birth control with unrivalled effectiveness. The pill can effectively prevent pregnancy and alleviate menstrual disorder when used correctly. Many biochemical profiles of women taking oral contraceptives are disturbed due to metabolic alterations induced by its hormone content. The study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, during the period of July 2016 to June 2017 to evaluate the status of serum calcium and magnesium in oral contraceptive user women. For this study, 120 age-matched women were selected and grouped as 60 oral contraceptive user women and 60 non-oral contraceptive user women. Data were analyzed with the help of SPSS version 21. Mean±SD level of serum calcium and magnesium were 9.50±0.70 mg/dl and 1.81±0.13 mg/dl in oral contraceptive user women, while in normal healthy women the levels were 9.03±1.69 mg/dl and 2.10±0.17 mg/dl respectively. No significant difference of serum calcium between two groups was observed (p>0.05). Serum magnesium significantly reduced in oral contraceptive users when compared with non-oral contraceptive users (p<0.001). The study showed no significant difference in serum calcium level in contraceptive group when compared with noncontraceptive user group and serum magnesium level was significantly reduced in oral contraceptive users when compared to normal healthy group.Bangladesh J Med Biochem 2017; 10(2): 64-68

scholarly journals Status of Serum Iron and Copper in Women Taking Oral Contraceptive

2018 ◽  
Vol 10 (1) ◽  
pp. 5-9
Author(s):  
F Hasanat ◽  
PK Chakroborty ◽  
A Hasanat ◽  
SK Sharmin ◽  
MB Mannan ◽  
...  
Keyword(s):  
Oral Contraceptive ◽  
Serum Iron ◽  
Oral Contraceptive Pill ◽  
Copper Level ◽  
Oral Contraceptive User ◽  
Oral Contraceptive Pills ◽  
Contraceptive User ◽  
Contraceptive Pills ◽  
The Status ◽  
Human Need

The oral contraceptive pill fulfills the great human need for birth control with unrivalled effectiveness. The pill can effectively prevent pregnancy and alleviate many menstrual disorders when used correctly. Many biochemical profiles of women taking oral contraceptives are disturbed due to metabolic alterations induced by its hormone content. The study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, during the period of July 2016 to June 2017 to evaluate the status of serum iron and copper in women taking oral contraceptive pills. For this study 120 agematched women were selected and grouped as 60 oral contraceptive user women and 60 non-oral contraceptive user women. Data were analyzed with the help of SPSS version 21. Mean(±SD) level of serum iron and copper were 155.20±21.94 mg/dl and 157.6±14.75 mg/dl in oral contraceptive user women, while in normal healthy women the levels were 103±19.11 mg/dl and 126.28±17.18 mg/dl respectively. Serum iron and copper levels were significantly increased in oral contraceptive user group when compared with that of normal healthy group (p<0.001). From this study it can be concluded that there is significant association of serum iron and copper level with oral contraceptives.Bangladesh J Med Biochem 2017; 10(1): 5-9

scholarly journals A Study of Serum Calcium and Magnesium Levels in Idiopathic Epilepsy Patients of Hubli, Karnataka, India

2021 ◽  
Vol 8 (25) ◽  
pp. 2187-2191
Author(s):  
Chandrashekar Kachapur ◽  
Seetaram N. Kallimani ◽  
Gayathri B.H ◽  
Ishwar S. Hasabi ◽  
Zahura M. Devarhoru
Keyword(s):  
Serum Calcium ◽  
Calcium Influx ◽  
Serum Magnesium ◽  
Idiopathic Epilepsy ◽  
Total Serum ◽  
Cross Sectional ◽  
Total Serum Calcium ◽  
Study Results ◽  
Significant Difference ◽  
Calcium And Magnesium

BACKGROUND Magnesium is a potential modulator of seizure activity because of its ability to antagonize the excitatory calcium influx through N-methyl-D-aspartate (NMDA) receptor which is thought to play a role in many human forms of epilepsy. When the extracellular concentration of calcium ion falls below normal, the nervous system becomes more excitable, allowing easy initiation of action potentials. Consequently, hypocalcaemia causes seizures because of its action of increasing excitability in the brain. We wanted to estimate the serum concentration of calcium and magnesium in idiopathic epilepsy patients and its co-relation. METHODS 94 cases of idiopathic epilepsy with breakthrough seizures admitted to KIMS Hospital, Hubli, meeting the inclusion criteria were considered for the study which was for 2-years’ time period. It’s a single centred, time bound and cross sectional study. RESULTS Mean serum calcium was low 8.36 ± 0.45 mg / dL and mean serum magnesium was 1.79 ± 0.28 mg / dL. 64.9 % had total serum calcium less than 8.5 mg / dL and 44.7 % had serum magnesium of < 1.8 mg / dL. 35.1 % had both low calcium and magnesium. There was significant difference in mean serum calcium with respect to number of episodes. There was no significant difference in mean serum magnesium with respect to number of episodes. CONCLUSIONS Serum calcium and magnesium levels which play a role in seizure initiation should be measured in all idiopathic epilepsy patients with breakthrough seizures as a seizure trigger. Considering the role of calcium and magnesium in the pathophysiology of seizures and by evaluating the results from the present study, breakthrough seizure could be provoked by hypocalcaemia and hypomagnesemia. Hence they may be used for the treatment of intractable seizures. KEYWORDS Calcium, Magnesium, Idiopathic Epilepsy

Clustering of serum calcium and magnesium concentrations in siblings.

1986 ◽  
Vol 32 (2) ◽  
pp. 349-350 ◽  
Author(s):  
R B Payne ◽  
D P Jones ◽  
A P Walker ◽  
R T Evans
Keyword(s):  
Serum Concentration ◽  
Total Variation ◽  
Serum Calcium ◽  
Serum Magnesium ◽  
Reference Interval ◽  
Magnesium Homeostasis ◽  
Normal Reference ◽  
Calcium And Magnesium ◽  
Altered Serum

Abstract Concentrations of both serum calcium, adjusted for albumin, and serum magnesium of siblings from 23 families were found to cluster around different concentrations within the normal reference interval. Variation between families accounted for 37% of the total variation in calcium and 28% of that in magnesium. A disturbance of serum calcium or magnesium homeostasis in an individual resulting in an altered serum concentration that remains within the reference interval might be recognized by examining values in siblings.

The Oral Contraceptive User

1988 ◽  
Vol 67 (1) ◽  
pp. 27-31 ◽  
Author(s):  
øjvind Lidegaard ◽  
Karsten Overgaard ◽  
Ole Hauch
Keyword(s):  
Oral Contraceptive ◽  
Oral Contraceptive User ◽  
Contraceptive User

INSULIN EFFECTS ON CALCIUM, MAGNESIUM AND PHOSPHATE METABOLISM IN RATS

1974 ◽  
Vol 75 (4) ◽  
pp. 748-755 ◽  
Author(s):  
Erling T. Mellerup
Keyword(s):  
Serum Calcium ◽  
Indirect Effects ◽  
Serum Magnesium ◽  
Serum Phosphate ◽  
The Other ◽  
Phosphate Metabolism ◽  
Insulin Administration ◽  
Other Hand ◽  
Calcium Magnesium ◽  
Calcium And Magnesium

ABSTRACT Serum calcium as well as serum magnesium increased after insulin administration to rats. The increase in serum calcuim was followed by a decrease, which did not occur in thyroid-parathyroidectomized animals. The increase in both serum calcium and magnesium may be secondary to a diminished uptake of calcium and magnesium into bone. On the other hand this may be secondary to a decreased uptake of phosphate into bone. The decreased uptake of phosphate into bone may be secondary to the decrease in serum phosphate, which is a well-known phenomenon after insulin administration. In addition to all these indirect effects, insulin directly increased the uptake of magnesium into muscle and probably also the liver, thus counteracting the increase in serum magnesium.

scholarly journals The Effect of Oral Contraceptive Pills on The Gene Mutation of Factor V Leiden among Sudanese Women

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Kawthar Abdelgaleil Mohammed Salih ◽  
Hiba Abdelmalik ◽  
Hiba Babiker ◽  
Ahmed Bakheet Abd Alla
Keyword(s):  
Oral Contraceptive ◽  
Gene Mutation ◽  
Oral Contraceptive Pill ◽  
Factor V Leiden ◽  
Factor V ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pill ◽  
Contraceptive Pills ◽  
Significant Difference ◽  
The Impact

Oral contraceptive pills are problems for women, often have many effects, and may cause several diseases. The purpose of this research was to determine the impact of oral contraceptive pills on factor V sufferers. This case-control study conducted in Khartoum Sudan during the period from April to November 2018. The study included 50 women who used oral contraceptive as a case and 50 women who did not use oral contraceptive pills as a control, all of whom were verbally informed of the study and approved for participation. The PCR do for each sample. The results obtained from cases show that the mean age is 30±5.5 and divided into three groups less than 20 with a lower frequency of 4 % (2/50), (20-35) with a higher incidence of 80 % (40/50) and a higher rate of 16 % (8/50) for more than 35 years. Most cases use the oral contraceptive pill for more than one year at a frequency of 60% (30/50) with a mean of 2±0.8. The most frequent oral contraceptive pill use was levonorgestrel 88% (44/50), followed by desogestrel 12% (6/50). The study concludes that there is no significant difference in gene mutation between case and control. There was also an insignificant association between the mutation and demographic data.

scholarly journals Comparative analysis of serum calcium and magnesium as a better predictor in cases of mild and severe pre-eclampsia.

2020 ◽  
Vol 27 (08) ◽  
pp. 1722-1727
Author(s):  
Farheen Aslam ◽  
Irum Hayat ◽  
Faizan Ahmad Zakir ◽  
S. Sabahat Haider ◽  
Shams Un Nisa ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Serum Magnesium ◽  
Serum Levels ◽  
Mean Value ◽  
Control Group ◽  
Mortality And Morbidity ◽  
Nulliparous Women ◽  
Gynecology And Obstetrics ◽  
Research Population ◽  
Calcium And Magnesium

Objectives: The hypertensive disorders of pregnancy (HDP), especially severe preeclampsia are most common cause of neonatal and maternal mortality and morbidity. Alteration in metabolism of calcium and magnesium during pregnancy is considered to be one of etiological factor for pre-elampsia. Study Design: Case-control study. Settings: Departments of Pathology and Gynecology and Obstetrics, Bahawal Victoria Hospital. Period: September 2018 to June 2019. Material & Methods: To compare whether serum levels of calcium or magnesium showed significant change in mild and severe preeclamptic patients as compared to control group. Research population consisted of pregnant females that were divided into three groups. The mild and severe preeclamptic groups comprised of 55 and 26 participants respectively and 45 were included in control group. The serum calcium and magnesium levels were measured in these groups. Results: Maximum numbers of preeclamptic cases were presented at 28-32 week of gestation while severe pre-eclamptic group showed most cases in 33-36 weeks. In both groups, most of cases occurred in multiparous women as compared to nulliparous women. The normotensive group showed serum calcium and magnesium levels of 9.08±0.63 and2.12±0.22mg/dl while mild preeclamptic (mPE) had mean value of 7.91±0.64 and 1.58±0.42mg/dl and measurement were 7.67±0.48 and 1.26±0.44 in cases of severe pre eclampsia (sPE). Serum magnesium levels were significantly lower in sPE as compared to mPE (<0.0001) while difference was not statistically significant for serum calcium level (0.14). Conclusion: Both decrease level of serum calcium and magnesium might be risk factor in development of preeclampsia with more emphasis on role of low magnesium as a prognostic marker in severe preeclamptic cases.

scholarly journals Comparative Evaluation of Serum Calcium and Magnesium Level in Preeclamptic and NonPreeclamptic Women in a Tertiary Hospital in Southern Nigeria

2018 ◽  
Vol 14 (12) ◽  
pp. 437
Author(s):  
Allagoa DO. ◽  
Agbo OJ. ◽  
Orluwene CG.
Keyword(s):  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Serum Magnesium ◽  
Serum Levels ◽  
Tertiary Hospital ◽  
Magnesium Level ◽  
P Value ◽  
Serum Magnesium Level ◽  
Calcium And Magnesium

Background: Calcium and magnesium are two micronutrients whose role in the development of preeclampsia has been investigated over the years. There is paucity of studies on the role of serum levels of calcium and magnesium in the development of preeclampsia in south-south Nigeria. Objective: Our study evaluated the serum level of calcium and magnesium in preeclamptic and non preeclamptic women in a Tertiary Hospital in southsouth Nigeria. Methodology: We carried out a comparative study in which 52 preeclamptic and 52 non preeclamptic women, who satisfied the eligibility criteria, were enrolled for the study. Data entry and statistical analysis was done using statistical software (IBM SPSS® for windows version 21.0). Data were analyzed for mean and standard deviation. Comparison of serum levels of elements between the two groups was performed by student t-test, and P value < 0.05 was considered as statistically significant. Results: The serum calcium level was statistically lower in the women who developed preeclampsia compared to those who did not (8.37±0.91 mg/dl vs 9.33±1.15mg/dl, p<0.001). The serum magnesium level was not statistically different between women who had preeclampsia and those who did not (1.79±0.24mg/dl vs 1.88±0.37mg/dl, p = 0.102). The systolic and diastolic blood pressure showed a significant negative correlation with serum calcium level, unlike serum magnesiun level in those that had preeclampsia. Conclusion: This study showed that women who developed preeclampsia demonstrated reduced serum calcium level and no reduction in serum magnesium level. This study support the hypothesis that hypocalcaemia, unlike hypomagnecaemia, is a possible aetiology of preeclampsia.

scholarly journals A study of maternal serum calcium and serum magnesium levels in pre-eclamptic and normotensive pregnancies

2020 ◽  
Vol 9 (8) ◽  
pp. 3129
Author(s):  
Pranshi Gupta
Keyword(s):  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Serum Magnesium ◽  
Maternal Serum ◽  
Magnesium Level ◽  
Serum Magnesium Level ◽  
Related Factors ◽  
Calcium And Magnesium ◽  
Major Factors

Background: Hypertensive disorders are major factors responsible for morbidity and mortality in pregnancy and pre-eclampsia is the leading cause. The etiopathology of pre-eclampsia is not known even after significant research done on it. A strong strategy in its management is to try to reduce the incidence and severity by predicting its occurrence. In this study, the effect of serum calcium and serum magnesium levels is being investigated with occurrence pre-eclampsia.Methods: Total 120 pregnant patients attending Tirath Ram Shah Hospital were included in the study. They were divided into two groups namely normotensive and hypertensive of 60 each. The serum calcium and serum magnesium levels were estimated and the correlation of these levels was studied with the pre-eclampsia related factors. The data was analysed by application of statistical test of significance.Results: Mean serum calcium level in the normotensive group was 10.119±1.27 mg/dl while mean serum calcium level in the hypertensive group was 9.461±1.164. Mean serum magnesium level in the normotensive women in the study was 1.979±0.405 mg/dl. In the hypertensive women, mean serum magnesium level was 1.723±0.414 mg/dl.Conclusions: This study shows that low levels of calcium and magnesium are found in serum of pre-eclampsia patients as compared to normotensive cases of the study population. The severity of pre-eclampsia is inversely proportional to the levels of serum calcium and magnesium.

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