scholarly journals Experience of Pandemic Influenza A (H1N1) 2009 at Dhaka Medical College Hospital

1970 ◽  
Vol 28 (1) ◽  
pp. 63
Author(s):  
Quazi Tarikul Islam

DOI: 10.3329/jbcps.v28i1.4648 J Bangladesh Coll Phys Surg 2010; 28: 63

1970 ◽  
Vol 11 (1) ◽  
pp. 3-6
Author(s):  
Quazi Tarikul Islam ◽  
Azizul Kahhar ◽  
Syed Mohammad Arif ◽  
Ahmedul Kabir ◽  
Khan Mohammed Arif ◽  
...  

The first case of 2009 pandemic influenza A (H1N1) virus infection in Bangladesh was documented on June 18. Subsequently, persons with suspected cases of infection and contacts of those with suspected infection were tested. Individuals in whom infection was confirmed were hospitalized and quarantined, and some of them were closely observed for the purpose of investigating the nature and duration of the disease. In Dhaka Medical College Hospital, there were 28 admitted patients in flu ward and 2335 registered suspected H1N1 influenza cases attended in flue corner but 833 highly suspected cases were recorded in case record form. We describe the epidemiological characteristics of 28 indoor (flu ward) and 833 outdoor (flu corner) patients. Most of them were in between 20 to 30 years age group. Among 833 outdoor patients 611(73.34%) were male and 222(26.65%) were female. 354 (42.49%) patients were student, 195 (23.40%) were service holder. No patients (indoor) had any serious underlying medical conditions. Keywords: Pandemic influenza A (H1N1), Dhaka Medical College Hospital, Bangladesh, epidemiology. DOI:10.3329/jom.v11i1.4259 J Medicine 2010: 11: 3-6


1970 ◽  
Vol 11 (2) ◽  
pp. 119-123
Author(s):  
Quazi Tarikul Islam ◽  
Azizul Kahhar ◽  
Syed Mohammad Arif ◽  
HAM Nazmul Ahasan ◽  
Md Mahmudur Rahman Siddiqui ◽  
...  

Introduction: Bangladesh recorded the first case of 2009 pandemic influenza A (H1N1) virus infection on 18thJune 2009. This report describes the clinical and epidemiological characteristics of both the indoor and outdoorpatients reporting in Flu Ward and Flu Corner of Dhaka Medical College Hospital.Methods: This cross-sectional study was done on highly suspected 833 registered outdoor (flu corner) and 28indoor patients admitted in Flu ward of Dhaka Medical College Hospital during the study period of August 2009 toNovember 2009. A suspected case was defined as an influenza-like illness and either a history of travel to a countrywhere infection had been reported in the previous 7 days or an epidemiologic link to a person with confirmed orsuspected infection in the previous 7 days. A confirmed case was defined by a positive real-time reverse-transcriptasepolymerase chain reaction (RT-PCR) assay.Results: Most of the patients were in between 20 to 30 years age group. Indoor patients presented with mostly fever(92.85%), rhinorrhea (71.42%), shortness of breathe (89.28%) and cough (64.28%). Maximum duration of feverin indoor patients was 4 days. RT-PCR from throat swab sample for H1N1 tested positive in 9 (32.14%) indoorpatients. Out of the 833 outdoor patients 596(71.54%) patients had fever, 585(70.22%) had cough, 410(49.21%)had rhinorrhea and 314(37.69%) had sore throat. Only 2(7.14%) admitted patients died of flu.Conclusion: Despite widespread infection mortality rate is quite low. Prompt implementation and adherence tonational guidelines on 2009 pandemic influenza A (H1N1) should be encouraged.Keywords: Pandemic influenza A (H1N1); Dhaka Medical College Hospital; Bangladesh.DOI: 10.3329/jom.v11i2.5452J MEDICINE 2010; 11 : 119-123


2020 ◽  
Vol 22 (2) ◽  
pp. 110-117
Author(s):  
Md Mahmudul Islam ◽  
Khondkar AK Azad ◽  
Md Aminul Islam ◽  
Rivu Raj Chakraborty

Background: Chest trauma is responsible for 50% of deaths due to trauma. This kind of death usually occurs immediately after the trauma has occurred. Various therapeutic options have been reported for management of chest injuries like clinical observation, thoracocentesis, tube thoracostomy and open thoracotomy. Objective: To observe the pattern and outcome of management in chest trauma Methods: This is an observational study carried out in Casualty department of Chittagong Medical College Hospital (CMCH), Chittagong, between April 2015 to March 2016. Our study was included all patients, both sexes, following chest injury at Casualty units of Chittagong Medical College Hospital. All the data were recorded through the preformed data collection sheet and analyzed. Result: The mean age was found 37.7±18.1 years with range from 12 to 80 years. Male female ratio was 11.8:1. The mean time elapsed after trauma was found 6.1±3.1 hours with range from 1 to 72 hours. Almost one third (35.7%) patients was affecting road traffic accident followed by 42(27.3%) assault, 35(22.7%) stab injury, 15(9.7%) fall and 7(4.5%) gun shot . More than three fourth (80.5%) patients were managed by tube thoracostomy followed by 28(18.2%) observation and 2(1.3%) ventilatory support. No thoracotomy was done in emergency department. 42(27.2%) patients was found open pneumothorax followed by 41(26.6%) rib fracture, 31(20.1%) haemopneumothorax, 14(9%) simple pneumothorax, 12(7.8%) haemothorax, 6(3.9%) chest wall injury, 5(3.2%) tension pneumothorax, and 3(1.9%) flail chest. About the side of tube 60(39.0%) patients were given tube on left side followed by 57(37.0%) patients on right side, 9(5.8%) patients on both (left & right) side and 28(18.2%) patients needed no tube. Regarding the complications, 13(30%) patients had persistent haemothorax followed by 12(29%)tubes were placed outside triangle of safety, 6(13.9%) tubes were kinked, 6(13.9%) patients developed port side infection, 2(4.5%)tube was placed too shallow, 2(4.5%) patients developed empyema thoracis and 2(4.5%) patients developed bronchopleural fistula. The mean ICT removal information was found 8.8±3.6 days with range from 4 to 18 days. Reinsertion of ICT was done in 6(4.7%) patients. More than two third (68.2%) patients were recovered well, 43(27.9%) patients developed complication and 6(3.9%)patients died. More than two third (66.9%) patients had length of hospital stay 11-20 days. Conclusion: Most of the patients were in 3rd decade and male predominant. Road traffic accident and tube thoracostomy were more common. Open pneumothorax, rib fracture and haemopneumothorax were commonest injuries. Nearly one third of the patients had developed complications. Re-insertion of ICT needed almost five percent and death almost four percent. Journal of Surgical Sciences (2018) Vol. 22 (2) : 110-117


Author(s):  
José Alberto Choreño-Parra ◽  
Luis Armando Jiménez-Álvarez ◽  
Gustavo Ramírez-Martínez ◽  
Alfredo Cruz-Lagunas ◽  
Mahima Thapa ◽  
...  

Abstract The differentiation of influenza and COVID-19 could constitute a diagnostic challenge during the ongoing winter due to their clinical similitude. Thus, novel biomarkers that enable distinguishing both diseases are required. Here, we evaluated whether the surfactant protein D (SP-D), a collectin produced at the alveolar epithelium with known immune properties, was useful to differentiate pandemic influenza A(H1N1) from COVID-19 in critically ill patients. Our results revealed high serum SP-D levels in severe pandemic influenza but not COVID-19 patients. This finding was validated in a separate cohort of mechanically ventilated COVID-19 patients who also showed low plasma SP-D levels. However, plasma SP-D levels did not distinguish seasonal influenza from COVID-19 in mild-to-moderate disease. Finally, we found that high serum SP-D levels were associated with mortality and renal failure among severe pandemic influenza cases. Thus, our studies have identified SP-D as a unique biomarker expressed during severe pandemic influenza but not COVID-19.


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