scholarly journals Study of Thyroid Function Status in Type 2 Diabetic Patients

KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 95-98
Author(s):  
Kamrunnahar Alo ◽  
Shyamal Chandra Banik ◽  
Safayet Ahammed ◽  
Ayesha Yasmin ◽  
Tania Rahman

Background: Thyroid dysfunction specially hypothyroidism may occur in type 2 diabetic patients. Objective: To observe thyroid function status in type 2 diabetic patients Materials and Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka from July 2016 to June 2017. Total 60 subjects including male and female, age ranged from 40 to 60 years were included in this study, among them 30 were non-diabetic subjects and 30 were type 2 diabetic patients. Results: In this study, mean serum TSH level was significantly (p<0.001) higher and serum FT4 level was significantly (p<0.01) lower in diabetic patients than that of apparently healthy non-diabetic subjects. Serum FT3 level was lower in type 2 diabetic patients in comparison to that of non-diabetic subjects but the difference was not statistically significant. However, among the diabetic patients 10% were subclinical hypothyroid and 6.67% were hypothyroid Conclusion: The present study reveals that hypothyroidism occurs in type 2 diabetic patients. So type 2 diabetic patients should measure thyroid hormone levels routinely to detect thyroid dysfunction. KYAMC Journal Vol. 10, No.-2, July 2019, Page 95-98

Diabetology ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 1-10
Author(s):  
Sara Cherchi ◽  
Alfonso Gigante ◽  
Maria Anna Spanu ◽  
Pierpaolo Contini ◽  
Gisella Meloni ◽  
...  

Diabetic retinopathy (DR) is one of the main causes of visual loss in individuals aged 20–64 years old. The aim of this study was to investigate, in a multicenter retrospective cross-sectional study, sex-gender difference in DR in a large sample of type 2 diabetic patients (T2DM). 20,611 T2DM regularly attending the units for the last three years were classified as having: (a) No DR (NDR), (b) nonproliferative DR (NPDR), or (c) preproliferative/proliferative DR (PPDR). DR of all grades was present in 4294 T2DM (20.8%), with a significant higher prevalence in men as compared to women (22.0% vs. 19.3% p < 0.0001). Among DR patients, both NPDR and PPDR were significantly more prevalent in men vs. women (p = 0.001 and p = 0.0016, respectively). Women had similar age and BMI, but longer diabetes duration, worse glycemic metabolic control, and more prevalence of hypertension and chronic renal failure (CRF) of any grade vs. men. No significant differences between sexes were evident in term of drug therapy for diabetes and associate pathologies. Conclusions: In this large sample of T2DM, men show higher prevalence of DR vs. women, in spite of less represented risk factors, suggesting that male sex per se might be a risk factor for DR development.


2017 ◽  
Vol 8 (1) ◽  
pp. 47-51
Author(s):  
Md Towhidur Rahman ◽  
AS Mohiuddin ◽  
Md Mofazzal Sharif ◽  
Jafreen Sultana ◽  
Fahmida Yeshmine ◽  
...  

Background: Patients with diabetic peripheral neuropathy (DPN) have distal, symmetrical form of the disorder characterized by numbness, burning feet, pins-and-needles sensations and lightning pain. This study was designed to find out the difference between 2 Dimentional (D)-Brightness (B) mode high resolution ultrasonographically measured cross sectional areas of median nerve in type 2 diabetic patients with peripheral neuropathy and those of non-diabetic healthy adult subjects.Methods: This case-control study was done on 180 subjects aged 27-67 years in the department of Radiology and Imaging, BIRDEM from January 2012 to December 2013. Out of them 90 diabetic patients with peripheral neuropathy diagnosed electrophysiologically by nerve conduction study (NCS) were considered study group and age, sex and weight compatible 90 healthy subjects were considered as control group. Measurement of cross sectional areas of median nerve was performed first by the investigator himself purposefully, consecutively and subsequently confirmed by a radiologist in the department of Radiology and Imaging, BIRDEM, who did not know the subjects’ condition to eliminate bias. The major axis, minor axis and the cross sectional areas (CSA) of the median nerve were measured at the carpal tunnel.Results: In this study, the mean cross sectional areas (mm2) of median nerve healthy subjects was 7.78±1.00 mm2 and in diabetic patients with peripheral neuropathy was 13.67±2.97 mm2. The difference mean CSA of median nerve of diabetic subjects with peripheral neuropathy and control subjects were statistically significant (p<0.05) in unpaired ‘t’ test.Conclusion: This study showed that there is a significant difference between the cross sectional areas of median nerve in diabetic subjects with peripheral neuropathy and healthy adult subjects. The mean cross sectional areas of median nerve were increased in diabetic patients with peripheral neuropathy compared to control group.Birdem Med J 2018; 8(1): 47-51


2019 ◽  
Vol 192 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Hadi rostamkhani ◽  
Ali Awsat Mellati ◽  
Banafsheh Sadat Tabaei ◽  
Mohammadhossein Alavi ◽  
Seyedeh Neda Mousavi

2014 ◽  
Vol 171 (5) ◽  
pp. 641-648 ◽  
Author(s):  
Yanyun Hu ◽  
Fang Liu ◽  
Jing Shen ◽  
Hui Zeng ◽  
Lianxi Li ◽  
...  

ObjectiveSerum cystatin C (CysC) is a sensitive marker of kidney function and recent studies have shown that CysC plays a critical role in degenerative diseases in both the central and the peripheral nervous systems. The aim of this study was to explore the relationship between serum CysC and diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes.MethodsIn total, 937 type 2 diabetic patients were enrolled in this cross-sectional study. Serum CysC concentration was measured by immunoturbidimetry. DPN was evaluated by neurological symptoms, neurological signs, neurothesiometer, and electromyogram.ResultsSerum CysC levels were significantly higher in DPN patients (1.3 (1.1–1.5) mg/l) compared with patients with signs of DPN (1.1 (0.9–1.3) mg/l, P<0.001) and non-DPN patients (1.0 (0.9–1.3) mg/l, P<0.001). Multiple regression analysis revealed that DPN was associated with age, diabetes duration, HbA1c, and serum CysC. Spearman's correlation analysis showed that serum CysC was closely related with age, sex, diabetes duration, hypertension, glomerular infiltration rate, and serum creatinine (Cr) level. The patients were divided into quartiles according to the serum CysC levels. Compared with quartile 1 (referent), the risk of DPN was significantly higher in quartile 2 (odds ratio (OR), 1.753; 95% CI, 1.055–2.912; P<0.05), quartile 3 (OR, 2.463; 95% CI, 1.445–4.917; P<0.01), and quartile 4 (OR, 5.867; 95% CI, 2.075–16.589; P<0.01). Receiver-operating characteristic analysis revealed that the optimal cutoff point of serum CysC to indicate DPN was 1.25 mg/l in male patients and 1.05 mg/l in female patients. High serum CysC level indicated a onefold higher risk of DPN.ConclusionsHigh serum CysC level is closely associated with DPN and may be a potential biomarker for DPN in type 2 diabetic patients.


2019 ◽  
Vol 4 (1) ◽  
pp. 19
Author(s):  
Mia Widha Anindita ◽  
Noor Diani ◽  
Ifa Hafifah

Introduction: Diabetes mellitus is a chronic disease, and type 2 DM accounts for 90-95% of total diabetes. Adherence to implementation of physical exercise is very necessary for patients with DM. Self efficacy in diabetic patients can improve the adherence for medications and success to control the sugar levels.Methods: We aimed to analyze the correlation between self efficacy and adherence to physical exercises in type 2 diabetes patients. This is a descriptive cross-sectional study with purposive sampling method. In total, we recruit 60 respondents during December 2018. We used two types of questionnires: self efficacy and adherence to physical exercises to measure the variable of interest.Result: We found that there was a correlation between self efficacy and adherence to physical exercises in type 2 diabetic patients (p<0.001).Conclusion: Appropriate self efficacy could improve patients’ adherence to manage the advised physical examination.


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