scholarly journals Diagnosis of Resistant Hypertension

2017 ◽  
Vol 8 (1) ◽  
pp. 196-198
Author(s):  
Moniruzzaman Khan ◽  
Sharif Shaila Islam
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Resistant Hypertension ◽  
Antihypertensive Agents ◽  
Cardiovascular Death ◽  
Uncontrolled Hypertension ◽  
Elevated Blood ◽  
Medical College ◽  
Obstructive Sleep ◽  
Secondary Causes

Hypertension is a major risk factor of cardiovascular death in Bangladesh and worldwide. Resistant hypertension as well as uncontrolled hypertension with 3 or more antihypertensive agents is increasingly common in clinical practice. Clinicians should exclude pseudoresistant hypertension, which results from nonadherence to medications or from elevated blood pressure related to the white coat syndrome. Resistant hypertension may be associated with secondary causes of hypertension including obstructive sleep apnea or primary aldosteronism.Northern International Medical College Journal Vol.8(1) July 2016: 196-198

scholarly journals Low Physical Activity Is a Determinant for Elevated Blood Pressure in High Cardiovascular Risk Obstructive Sleep Apnea

2013 ◽  
Vol 59 (8) ◽  
pp. 1218-1227 ◽  
Author(s):  
M. Mendelson ◽  
R. Tamisier ◽  
D. Laplaud ◽  
S. Dias-Domingos ◽  
J.-P. Baguet ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Cardiovascular Risk ◽  
Sleep Apnea ◽  
Elevated Blood Pressure ◽  
Elevated Blood ◽  
High Cardiovascular Risk ◽  
Obstructive Sleep

Secondary Causes Of Resistant Hypertension: The Relative Significance Of Obstructive Sleep Apnea

2011 ◽  
Author(s):  
Rodrigo P. Pedrosa ◽  
Luciano F. Drager ◽  
Carolina C. Gonzaga ◽  
Marcio G. Sousa ◽  
Lilian K.G. de Paula ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Resistant Hypertension ◽  
Relative Significance ◽  
Obstructive Sleep ◽  
Secondary Causes

scholarly journals Resistant Hypertension and Obstructive Sleep Apnea

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Akram Khan ◽  
Nimesh K. Patel ◽  
Daniel J. O’Hearn ◽  
Supriya Khan
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Lifestyle Modification ◽  
Large Population ◽  
Antihypertensive Agents ◽  
The United States ◽  
Pressure Therapy ◽  
Obstructive Sleep

Hypertension (HTN) is a modifiable, highly prevalent risk factor for cardiovascular morbidity and renal dysfunction worldwide. In the United States, HTN affects one in three adults, contributes to one out of every seven deaths and to nearly half of all cardiovascular disease-related deaths. HTN is considered resistant when the blood pressure remains above goal despite lifestyle modification and administration of three antihypertensive agents of different classes including a diuretic. Large population-based studies have suggested that obstructive sleep apnea (OSA) is a risk factor for resistant HTN. The mechanism proposed is a pattern of intermittent hypoxia associated with hyperaldosteronism, increased sympathetic tone, endothelial dysfunction, and inflammation. In this review we discuss the association between OSA and resistant HTN, the physiologic mechanisms linking OSA with resistant HTN, and the effect of continuous positive airway pressure therapy (CPAP) on blood pressure in patients with resistant HTN. While the reduction in blood pressure with CPAP is usually modest in patients with OSA, a decrease of only a few mmHg in blood pressure can significantly reduce cardiovascular risk. Patients presenting to a center specializing in management of hypertension should be screened and treated for OSA as a potentially modifiable risk factor.

scholarly journals Effects of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea: a systematic review and meta-analysis of six randomized controlled trials

2017 ◽  
Vol 43 (5) ◽  
pp. 373-379 ◽  
Author(s):  
Qiang Lei ◽  
Yunhui Lv ◽  
Kai Li ◽  
Lei Ma ◽  
Guodong Du ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Resistant Hypertension ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Obstructive Sleep

ABSTRACT Objective: To evaluate systematically the effects of continuous positive airway pressure (CPAP) on blood pressure in patients with resistant hypertension and obstructive sleep apnea (OSA). Methods: The Cochrane Library, PubMed, ScienceDirect, and the Web of Science were searched for studies investigating the effects of CPAP on blood pressure in patients with resistant hypertension and OSA. The selected studies underwent quality assessment and meta-analysis, as well as being tested for heterogeneity. Results: Six randomized controlled trials were included in the meta-analysis. The pooled estimates of the changes in mean systolic blood pressure and mean diastolic blood pressure (as assessed by 24-h ambulatory blood pressure monitoring) were −5.40 mmHg (95% CI: −9.17 to −1.64; p = 0.001; I2 = 74%) and −3.86 mmHg (95% CI: −6.41 to −1.30; p = 0.00001; I2 = 79%), respectively. Conclusions: CPAP therapy can significantly reduce blood pressure in patients with resistant hypertension and OSA.

Prevalence, Characteristics, and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension

2019 ◽  
Vol 16 (11) ◽  
pp. 1414-1421 ◽  
Author(s):  
Esther Sapiña-Beltrán ◽  
Gerard Torres ◽  
Ivan Benitez ◽  
Ana Maria Fortuna-Gutiérrez ◽  
Paola Ponte Márquez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Blood Pressure Control ◽  
Resistant Hypertension ◽  
Pressure Control ◽  
Obstructive Sleep

scholarly journals Effect of CPAP on Blood Pressure in Patients With Obstructive Sleep Apnea and Resistant Hypertension

JAMA ◽  
2013 ◽  
Vol 310 (22) ◽  
pp. 2407 ◽  
Author(s):  
Miguel-Angel Martínez-García ◽  
Francisco Capote ◽  
Francisco Campos-Rodríguez ◽  
Patricia Lloberes ◽  
María Josefa Díaz de Atauri ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Resistant Hypertension ◽  
Obstructive Sleep
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