Eurocan plus report: feasibility study for coordination of national cancer research activities

Background: Much remains to be learned about the causes of several major cancers. Implementing and sustaining global initiatives aimed to advance cancer research requires concerted efforts among government agencies, the industry and philanthropic institutions. Aiming to tackle this challenge, in 2015 the Azrieli Foundation, Canada's International Development Research Centre, the Canadian Institutes of Health Research, and the Israel Science Foundation launched the Joint Canada-Israel Health Research Program (JCIHRP), a 7-year CA$35 million partnership that draws on the scientific strengths of Canadian, Israeli and low and middle income countries (LMICs) researchers in the broad field of biomedicine. Aim: JCIHRP aims to advance research and discovery in the biomedical sciences; encourage scientific collaboration between Canadian and Israeli researchers; and build capacity and foster scientific relations and collaborations with researchers and trainees in LMICs. Methods: JCIHRP will fund up to 30 research projects from 2015 to 2022 in diverse areas of the biomedical sciences (neurosciences, immunology, cancer and metabolism). So far, the program is supporting 9 projects in cancer research. Teams are led by a Canadian and Israeli principal investigators and a collaborator from a LMIC. Three years is the maximum duration of each grant and teams can request up to CA$1.17 million. The program launches 1 competition each year and activities are coordinated by a directors working group, which is responsible for program implementation and coordination among the agencies. Annual implementation timeline can be divided into 4 phases: competition development and application; proposals' eligibility, selection and decision; research phase; and reporting and monitoring. In deploying these phases, the funding partners have shared effort and costs. Results: Among cancer research projects, 4 teams are developing strategies to improve effectiveness of cancer immunotherapy. Five other teams use advanced genomics and protein engineering techniques to elucidate molecular mechanisms associated with tumor development, progression and resistance to therapy in pancreatic, breast, hepatic and brain cancer. These projects are supporting 26 established researchers in 7 Canadian, 6 Israeli and 9 institutions based in Brazil, Mexico, China, India, Argentina and Turkey. Additionally, 19 graduate students and 9 postdoctoral fellows are directly involved in research activities. Type of collaboration can be grouped into 2 categories: research and training (5 projects) and research, training and exchange (4 projects). Conclusion: JCIHRP multicentre funding model allows international integration of researchers promoting scientific advances, new collaborations and enhancing teams' overall competitiveness by prioritizing research topics with potential for global impact in cancer research.

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Building capacity for geospatial cancer research in Uganda: a feasibility study

The Lancet Global Health ◽

10.1016/s2214-109x(19)30096-8 ◽

2019 ◽

Vol 7 ◽

pp. S11 ◽

Cited By ~ 1

Author(s):

Kirsten Beyer ◽

Robert Lukande ◽

Simon Kasasa ◽

Danielle Savino ◽

Kavanya Gray ◽

...

Keyword(s):

Cancer Research ◽

Feasibility Study ◽

Building Capacity

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Comprehensive framework between environment and genomic stability: the open symposium of the Japanese Environmental Mutagen Society (JEMS) in 2019

Genes and Environment ◽

10.1186/s41021-019-0132-9 ◽

2019 ◽

Vol 41 (1) ◽

Author(s):

Katsuyoshi Horibata ◽

Masashi Sekimoto ◽

Kei-ichi Sugiyama

Keyword(s):

Cancer Research ◽

Genomic Stability ◽

Environmental Mutagen ◽

Conference Room ◽

Current Trends ◽

Research Activities ◽

Comprehensive Framework ◽

The Relationship

Abstract The open symposium of the Japanese Environmental Mutagen Society (JEMS), under the title of “Comprehensive framework between environment and genomic stability,” was held in the Main Conference Room of the Foundation for Promotion of Cancer Research, Tokyo, on June 8, 2019. To understand the relationship between genes and environmental mutagens, the symposium highlights the research activities in the fields of cancer, carcinogenesis and related diseases caused by genomic instabilities, including epigenetic and metabolomic alterations. The symposium was planned to help familiarize attendees with the current trends in research on genome safety. The organizers herein present a summary of the symposium.

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Global cervical cancer research: A scientometric density equalizing mapping and socioeconomic analysis

PLoS ONE ◽

10.1371/journal.pone.0261503 ◽

2022 ◽

Vol 17 (1) ◽

pp. e0261503

Author(s):

Dörthe Brüggmann ◽

Kathrin Quinkert-Schmolke ◽

Jenny M. Jaque ◽

David Quarcoo ◽

Michael K. Bohlmann ◽

...

Keyword(s):

Cervical Cancer ◽

Cancer Research ◽

Low Income ◽

The United States ◽

Scientific Quality ◽

Cancer Type ◽

Research Activity ◽

Socioeconomic Analysis ◽

Research Activities ◽

Density Equalizing Mapping

Cervical cancer has caused substantial morbidity and mortality for millions of women over the past decades. While enormous progress has been made in diagnosis, prevention and therapy, the disease is still fatal for many women—especially in low-income countries. Since no detailed studies are available on the worldwide research landscape, we here investigated the global scientific output related to this cancer type by an established protocol. The “New Quality and Quantity Indices in Science” platform assessed all relevant cervical cancer research published in the Web of Science since 1900. A detailed analysis was conducted including country-specific research productivity, indicators for scientific quality, and relation of research activity to socioeconomic and epidemiologic figures. Visualization of data was generated by the use of density equalizing map projections. Our approach identified 22,185 articles specifically related to cervical cancer. From a global viewpoint, the United States of America was the dominating country in absolute numbers, being followed by China and Japan. By contrast, the European countries Sweden, Austria, and Norway were positioned first when the research activity was related to the population number. When the scientific productivity was related to annual cervical cancer cases, Scandinavian countries (Finland #1, Sweden #4, Norway #5, Denmark #7), the Alpine countries Austria (#2) and Switzerland (#6), and the Netherlands (#3) were leading the field. Density equalizing mapping visualized that large parts of Africa and South America were almost invisible regarding the global participation in cervical cancer research. Our data documented that worldwide cervical cancer research activity is continuously increasing but is imbalanced from a global viewpoint. Also, the study indicated that global and public health aspects should be strengthened in cervical carcinoma research in order to empower more countries to take part in international research activities.

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Feasibility study of innovative regional turboprop: an overview of the European project IRON

MATEC Web of Conferences ◽

10.1051/matecconf/201930403014 ◽

2019 ◽

Vol 304 ◽

pp. 03014 ◽

Cited By ~ 1

Author(s):

Salvatore Corcione ◽

Vittorio Trifari ◽

Fabrizio Nicolosi ◽

Vincenzo Cusati ◽

Danilo Ciliberti ◽

...

Keyword(s):

Feasibility Study ◽

High Capacity ◽

Design Considerations ◽

Research Activities ◽

Surface Configuration ◽

Medium Range ◽

Funded Project ◽

The University ◽

Regional Jets ◽

Design Challenges

This paper deals with the research activities performed by the Design of Aircraft and Flight technologies group from the University of Naples Federico II within the European funded project IRON (Innovative turbopROp configuratioN). The research project is addressed to the feasibility study of an innovative high-capacity turboprop which is supposed to be competitive with respect to regional jets on short/medium range. This paper wants to provide some design considerations that must be addressed to design a high capacity turboprop, and to illustrate the configuration assessment through a Multi-Disciplinary Analysis and Optimization process performed to design such an innovative platform. A three-lifting surface configuration has been identified as the most promising layout for such a regional aircraft. Moreover, this paper wants to focus on some criticalities and design challenges that have been faced into designing a three-lifting platform.

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Cancer Researchers in Time of the Coronavirus Pandemic: A Time to Repurpose and Rethink

Asian Pacific Journal of Cancer Care ◽

10.31557/apjcc.2020.5.s1.161-163 ◽

2020 ◽

Vol 5 (S1) ◽

pp. 161-163

Author(s):

Mayank Singh ◽

Chandra Prakash Prasad

Keyword(s):

Cancer Research ◽

Drug Trials ◽

Principal Investigators ◽

Research Activities ◽

The World ◽

Catastrophic Loss ◽

Uncertain Future ◽

Near Future

Since the outbreak of the COVID-19 pandemic the cancer researchers and patients around the world are looking at a uncertain future. The lockdown that followed the outbreak has derailed all the cancer research activities around the world. Labs have been shut and ongoing experiemts and drug trials have to be halted. It has resulted in to a catastrophic loss to patients and researchers. Since securing grants for research in todays competitive world is hard and there are deadlines to be met so many postdocs and principal investigators around the world are looking at a uncertain future. The pandemic has resulted in diversion of resources to contain COVID-19 pandemic which will lad to funding crunch in near future. In this review we try to address different issues faced by cancer research labs and discuss potential ways to survive this pandemic professionally.

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