scholarly journals Development of Crohn’s Disease in a Child With SLC26A3-related Congenital Chloride Diarrhea: Report of the First Case in East Asia and a Novel Missense Variant

2021 ◽  
Vol 41 (2) ◽  
pp. 255-257
Author(s):  
Eun Sil Kim ◽  
Ju Sun Song ◽  
Chang-Seok Ki ◽  
Yon Ho Choe ◽  
Ben Kang
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
East Asia ◽  
Missense Variant ◽  
First Case ◽  
Congenital Chloride Diarrhea

scholarly journals Two for One: Coexisting Ulcerative Colitis and Crohn’s Disease

2002 ◽  
Vol 16 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Grant I Chen ◽  
Fred Saibil ◽  
Izabella Morava-Protzner
Keyword(s):  
Ulcerative Colitis ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Ulcerative Proctitis ◽  
Crohn’S Colitis ◽  
Crohn's Colitis ◽  
First Case ◽  
History Of

Three cases of coexisting ulcerative colitis and Crohn’s disease are presented. In the first case, the patient had a long-standing history of ulcerative proctitis before developing Crohn’s colitis. In the two remaining cases, the patients presented initially with Crohn’s disease of the ileum and, subsequent to resection, developed ulcerative colitis. Well-documented cases of patients diagnosed with both ulcerative colitis and Crohn’s disease are rare. The literature on such cases is reviewed, and the controversy over whether ulcerative colitis and Crohn’s disease are two distinct diseases is explored.

scholarly journals Crohn's Disease Associated with Sweet's Syndrome and Sjögren's Syndrome Treated with Infliximab

2005 ◽  
Vol 12 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Erina N. Foster ◽  
Khanh K. Nguyen ◽  
Rafiq A. Sheikh ◽  
Thomas P. Prindiville
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Sweet’S Syndrome ◽  
Sweet's Syndrome ◽  
First Case ◽  
Sjögren‘S Syndrome

The association of Crohn's disease (CD) and Sweet's syndrome is rare and the presence of Sjögren's syndrome in Crohn's disease is even rarer, with only three reports found in the literature. We describe two cases of Crohn's disease associated with Sweet's syndrome, one of which is the first case of CD and Sweet's concomitantly associated with Sjögren's syndrome. Both cases responded rapidly to Infliximab therapy with complete resolution of the skin lesions.

scholarly journals A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition

2016 ◽  
Vol 151 (4) ◽  
pp. 724-732 ◽  
Author(s):  
Dalin Li ◽  
Jean-Paul Achkar ◽  
Talin Haritunians ◽  
Jonathan P. Jacobs ◽  
Ken Y. Hui ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Gut Microbiome ◽  
Missense Variant ◽  
Human Gut ◽  
Microbiome Composition ◽  
Human Gut Microbiome

scholarly journals Löfgren Syndrome Developing during Infliximab Therapy for Crohn's Disease: A Case Report

1970 ◽  
Vol 9 (3) ◽  
Author(s):  
Isabel Coman MD, ◽  
J. Manuel Dominguez MD, ◽  
Annie Belisle MD
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Inflammatory Diseases ◽  
Biological Response ◽  
Necrosis Factor Alpha ◽  
First Case ◽  
Löfgren Syndrome ◽  
Mediastinal Adenopathy ◽  
Acute Form ◽  
Granulomatous Diseases

Tumour necrosis factor alpha (TNFα) antagonists are biological response modifiers increasingly used to effectively treat a wide array of inflammatory diseases such as Crohn’s disease and rheumatoid arthritis. Anti-TNFα agents are also used in the treatment of steroidrefractory granulomatous diseases, with reported success. Paradoxically, an increasing number of cases of anti-TNF–induced sarcoidosis are being reported. The acute form of sarcoidosis, Löfgren syndrome, is characterized by mediastinal adenopathy, erythema nodosum, arthralgia, and fever. This article describes the case of a patient with Crohn's disease who developed Löfgren syndrome during treatment with infliximab. To our knowledge, this is the first case of Löfgren syndrome developing during treatment with a TNFα antagonist.

scholarly journals SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects

PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0211328 ◽  
Author(s):  
Valerie Collij ◽  
Floris Imhann ◽  
Arnau Vich Vila ◽  
Jingyuan Fu ◽  
Gerard Dijkstra ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Gut Microbiome ◽  
Healthy Subjects ◽  
Missense Variant ◽  
Microbiome Composition

scholarly journals HEPATITIS AND PNEUMONITIS DURIN ADALIMUMAB THERAPY IN CROHN’ DISEASE: mind the histoplasmosis!

2014 ◽  
Vol 51 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Bruno do Valle PINHEIRO ◽  
Áureo de Almeida DELGADO ◽  
Julio Maria Fonseca CHEBLI
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Acute Hepatitis ◽  
Histoplasma Capsulatum ◽  
Febrile Illness ◽  
Needle Aspiration ◽  
Necrosis Factor Alpha ◽  
First Case ◽  
Tnf Α ◽  
Adalimumab Therapy

Context Tumor necrosis factor-alpha (TNF-α) inhibitor therapy plays a pivotal role in the management of moderate to severe inflammatory bowel disease. Because of the role of TNF-α in the host defenses, anti-TNF therapy has been associated with an increase the risks of granulomatous infections. Objective To report the first case of adalimumab-associated invasive histoplasmosis presenting as an acute hepatitis-like syndrome and febrile pneumonitis in a patient with Crohn’s disease. Method Case report of a patient with progressive histoplasmosis confirmed by percutaneous fine needle aspiration biopsy lung and urine Histoplasma antigen. Results We present the case of a young man with CD who developed pneumonia and acute hepatitis-like features caused by Histoplasma capsulatum infection during adalimumab therapy. To the best of our knowledge, this acute hepatitis-like manifestation has never been reported as a presentation of the histoplasmosis in patients with Crohn’s disease. Conclusions This case underscores the potential risk for serious infection that may arise in this setting and should alert clinicians to the need to consider the histoplasmosis diagnosis in patients presenting with acute hepatitis-like syndrome associated with prolonged febrile illness or pneumonitis during therapy with anti-TNF-α antibodies.

Sigmoidouterine Fistula in Crohn’s Disease: A First Case Report

2018 ◽  
Vol 25 (6) ◽  
pp. e65-e66
Author(s):  
Andrey Kotzev ◽  
Lachesar Tanchev ◽  
Lora Encheva ◽  
Nikolay Kovachev ◽  
Tatyana Betova
Keyword(s):  
Crohn’S Disease ◽  
Case Report ◽  
Crohn's Disease ◽  
First Case ◽  
Sigmoidouterine Fistula

scholarly journals Portal Vein Thrombosis and Systemic Amyloidosis in Crohn’s Disease: A Case Report and Review of the Literature

1996 ◽  
Vol 10 (5) ◽  
pp. 297-300 ◽  
Author(s):  
Gad Friedman ◽  
Gary E Wild
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Systemic Amyloidosis ◽  
Vein Thrombosis ◽  
First Case ◽  
S Deficiency ◽  
Inflammatory Bowel

Systemic amyloidosis and portal vein thrombosis are relatively rare complications of inflammatory bowel disease. The first case of a patient with Crohn’s disease presenting with both complications is presented. An acquired free protein S deficiency was disclosed in the patient, which may be responsible for the hypercoagulable state observed in Crohn’s disease and the nephrotic syndrome from amyloidosis.

Sign in / Sign up

Export Citation Format

Share Document