scholarly journals Diagnosis of vertebrogenic pain syndromes

2018 ◽  
pp. 4-12
Author(s):  
N. Svyrydova ◽  
V. Sereda ◽  
I. Dovgiy ◽  
A. Shcherbaty
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Mental Disorders ◽  
Medical Rehabilitation ◽  
Diagnosis And Treatment ◽  
Pain Syndromes ◽  
The World ◽  
Somatic Diseases ◽  
Large Groups ◽  
Chronic Pain Syndromes

Pain is a condition that is one of the most common diseases in the world. Many patients with vertebrogenic pain syndromes are multimorbidic, so they always receive field pharmacotherapy. Studies on multimorbidity have shown that chronic pain syndromes in the diagnosis and treatment are always interpreted as secondary, associated with somatic and mental disorders. Back pain can be divided into two large groups: vertebrogenic (degenerative, traumatic, inflammatory, neoplastic and other lesions of the vertebrae) and nonvertebrogenic genesis (stretching of ligaments and muscles, myofascial syndromes, fibromyalgia, somatic diseases, psychogenic factors, etc.). further). In the context of discussing vertebrogen pain syndromes, it is necessary to mention degenerative-dystrophic changes (osteochondrosis) of the spine primarily as in the vast majority of cases vertebroneurological pathology is associated with them. The following stages are distinguished: therapeutic, medical-rehabilitation, rehabilitation.

Spinal disorders and back pain

2018 ◽  
pp. 605-622
Author(s):  
Gavin Clunie ◽  
Nick Wilkinson ◽  
Elena Nikiphorou ◽  
Deepak R. Jadon
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Children And Adolescents ◽  
Chronic Back Pain ◽  
Holistic Approach ◽  
Musculoskeletal Symptoms ◽  
Spinal Disorders ◽  
Specific Diagnosis ◽  
Pain Syndromes ◽  
Chronic Pain Syndromes

The Oxford Handbook of Rheumatology, 4th edition, chapter on ‘Spinal disorders and back pain’ brings together a pragmatic approach to categorizing back pain, how to investigate disorders presenting with back pain, and how to treat adults, children, and adolescents with back pain. In the chapter, the management of back pain is separated into acute, subacute, and chronic presenting scenarios and the text makes reference to other chapters in the book where there may be some additional useful information (e.g. spondyloarthritis-associated back pain in Chapter 8 and chronic pain syndromes in Chapter 22). Notably the chapter is best read in conjunction with relevant sections in Chapter 3 (‘Regional musculoskeletal symptoms: making a working diagnosis’). The chapter makes reference to the need for a rigorous diagnostic approach to all the conditions which cause back pain, and at whatever age. There are subsections on how to assess paediatric spinal disorders and how to take a broad holistic approach to managing chronic back pain where there is no specific diagnosis.

Recurrent Tolosa-Hunt Syndrome

Cephalalgia ◽  
1992 ◽  
Vol 12 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Jan Hannerz
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Cluster Headache ◽  
Cranial Nerves ◽  
Chronic Fatigue ◽  
Hunt Syndrome ◽  
Pain Syndromes ◽  
Systemic Symptoms ◽  
Chronic Pain Syndromes ◽  
Periorbital Pain

Twenty consecutive patients with recurrent Tolosa-Hunt syndrome were studied. One had a parent who suffered from recurrent Tolosa-Hunt syndrome. Thirty-three percent of the patients had also recurrent periods of weeks to months of unilateral periorbital pain without ophthalmoplegia. One patient had cluster headache before the Tolosa-Hunt syndrome started. Some patients had involvement of cranial nerves outside the cavernous sinus region during Tolosa-Hunt syndrome and also between episodes. The same systemic symptoms, i.e. back pain, cold feet, arthralgia, gut problems, varices, vertigo, chronic fatigue, thrombophlebitis, memory deficiency and signs of inflammation in serum, occurred in Tolosa-Hunt syndrome as earlier found in patients with orbital venous vasculitis. Seventy-three percent of the patients had pathologic orbital phlebograms. All patients treated with steroids reacted promptly; four who developed chronic pain syndromes were treated satisfactorily with azathioprine.

Clinical Profiles of Patients with Chronic Pain Syndromes of Lumbosacral Localization

TRAUMA ◽  
2016 ◽  
Vol 17 (2) ◽  
pp. 78
Author(s):  
V.I. Romanenko ◽  
I.V. Romanenko ◽  
Yu.I. Romanenko
Keyword(s):  
Chronic Pain ◽  
Pain Syndromes ◽  
Clinical Profiles ◽  
Chronic Pain Syndromes

Radiotherapy-Specific Chronic Pain Syndromes in the Cancer Population: An Evidence-Based Narrative Review

2021 ◽  
Author(s):  
Jay Karri ◽  
Laura Lachman ◽  
Alex Hanania ◽  
Anuj Marathe ◽  
Mani Singh ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Narrative Review ◽  
Evidence Based ◽  
Pain Syndromes ◽  
Chronic Pain Syndromes

scholarly journals P124 Are chronic pain syndromes associated with a unique cytokine profile? A systematic review and meta-analysis

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Luke Furtado O'Mahony ◽  
Arnav Srivastava ◽  
Puja Mehta ◽  
Coziana Ciurtin
Keyword(s):  
Systematic Review ◽  
Chronic Pain ◽  
Meta Analysis ◽  
Pooled Analysis ◽  
Cross Sectional ◽  
Pain Syndromes ◽  
Newcastle Ottawa Scale ◽  
Cytokine Milieu ◽  
Analysis Models ◽  
Chronic Pain Syndromes

Abstract Background/Aims  The aetiology of primary chronic pain syndromes (CPS) is highly disputed. One theory suggests that pain is due to a pro-inflammatory cytokine milieu leading to nociceptive activation. We performed a systematic review and meta-analysis aiming to assess differences in cytokines levels in CPS patients versus healthy controls (HC). Methods  Human studies published in English from PubMed, MEDLINE/Scopus and Cochrane databases were searched from inception up to January 2020. We included full text cross-sectional or longitudinal studies with cytokine measurements in CPS patients and HC. We excluded studies with underlying organic pathology. Quality assessment was completed using a modified version of the Newcastle-Ottawa Scale. Random-effects meta-analysis models were used to report pooled effects and 95% CIs. Study registered with PROSPERO (CRD42020193774). Results  Initial search yielded 324 papers, 36 studies (3229 participants) eligible for systematic review and 26 studies (2048 participants) suitable for metaanalysis. There were reproducible findings supporting trends of cytokine levels comparing CPS patients with HC. Eotaxin (chemokine) however was consistently raised in CPS. Meta-analysis showed significantly increased tumour necrosis factor (TNF) (SMD=0.39, p = 0.0009, %95I=0.16-0.63, p < 0.001; I2=70%, Q2 p < 0.001), interleukin (IL)-6 (SMD=0.15, 8 (SMD=0.26, p = 0.01, 95%CI =0.05-0.47; I2=61%, Q2 p = 0.005) and IL-10 (SMD=0.61; %95 = 0.34-0.89, p < 0.001; I2 = 10%, Q2 p = 0.34) in CPS compared to HC. Conclusion  We found significant differences in peripheral blood cytokine profiles of CPS patients compared to HC. However, the distinctive profile associated with CPS includes both pro-inflammatory (TNF-α, IL-6, IL-8), and anti-inflammatory cytokines (IL-10) in pooled analysis, as well as chemokine (eotaxin) signatures. Disclosure  L. Furtado O'Mahony: None. A. Srivastava: None. P. Mehta: None. C. Ciurtin: None.

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