Evaluation of the effectiveness of an innovative approach to barrier amnioplasty in the surgical treatment of primary progressive pterygium

2021 ◽  
Vol 88 (2) ◽  
pp. 20-26
Author(s):  
A.N. Bochkareva ◽  
◽  
A.D. Pilipenko ◽  
V.V. Yegorov ◽  
G.P. Smolyakova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
High Efficiency ◽  
Cytological Examination ◽  
Postoperative Course ◽  
Primary Progressive ◽  
Postoperative Astigmatism ◽  
Examination Methods ◽  
Group 2 ◽  
Ph Metry ◽  
Group 1

The article evaluates the effectiveness of the proposed new method of barrier amnioplasty in the surgical treatment of primary progressive pterygium. The study involved 40 patients with primary progressive pterygium, who, depending on the method of barrier amnioplasty, were divided into 2 groups. Patients of group 1 underwent barrier amnioplasty in the limbus area, group 2 – in the area of plica semilunaris. Comparison of the methods was carried out using standard examination methods, as well as cytological examination and pH-metry of the lacrimal fluid. The developed method of amnioplasty in the area of the plica semilunaris has shown high efficiency: the time of corneal epithelialization was reduced by 1.7 times and the vitalization of the amnion by 1.5 times. An uncomplicated postoperative course of inflammatory and regenerative reactions made it possible to reduce the frequency of recurrence of pterygium, reduce the degree of postoperative astigmatism, and improve visual acuity

scholarly journals Effect of cryoprecipitate on neoangiogenesis in patients with purulent pyelonephritis

2020 ◽  
Vol 10 (1) ◽  
pp. 43-49
Author(s):  
Yuliya G. Chernova ◽  
Aleksandr I. Nejmark ◽  
Andrey P. Momot
Keyword(s):  
Surgical Treatment ◽  
Blood Vessels ◽  
Inflammatory Process ◽  
Conservative Therapy ◽  
High Efficiency ◽  
Control Group ◽  
Healthy Donors ◽  
Group 2 ◽  
Angiopoietin 2 ◽  
Group 1

The aim of the study is to investigate the effectiveness of conservative therapy with the inclusion of cryoprecipitate in its composition and its effect on the angiogenesis of renal blood vessels in patients with purulent pyelonephritis. Materials and methods. The study included 30 patients aged from 20 to 45 years (6 men, 24 women) with acute purulent pyelonephritis. All patients were assessed for markers of angiogenesis in blood plasma: vascular endothelial growth factor (VEGF-A), angiopoietin 1 (Ang1) and angiopoietin 2 (Ang2). The patients were divided into two groups. Patients of group 1 (n = 15) received conservative therapy with the inclusion of cryoprecipitate, patients of group 2 (n = 15) received surgical treatment. The control group consisted of 10 healthy donors aged 2035 years, whose blood angiogenesis markers were determined to obtain reference values. Results. In the course of preliminary studies, the blood content of angiogenesis markers was determined in 10 healthy donors. The level of VEGF-A in patients of both groups and the level of Ang1 in patients of group 1 at admission to the hospital significantly exceeded the corresponding values in the control group. In group 2 patients, the level of VEGF-A and Ang1 remained elevated during treatment, which indirectly indicated an ongoing inflammatory process. The level of Ang2 in patients of both groups did not change significantly. Conservative treatment of group 1 patients showed high efficiency, which was confirmed by positive dynamics of clinical and laboratory indicators, as well as data from instrumental examination. Conclusions. The results obtained indicate the effectiveness of conservative therapy with the administration of cryoprecipitate in patients with purulent pyelonephritis, and the effectiveness of such treatment is comparable to the effectiveness of surgical treatment . The use of cryoprecipitate has an endothelioprotective and anti-inflammatory effect on blood vessels, stabilizes the processes of angiogenesis, which contributes to limiting the inflammatory process and its regression.

scholarly journals Choice of surgical treatment for slipped capital femoral epiphysis with severe chronic displacement of the epiphysis

2021 ◽  
Vol 8 (4) ◽  
pp. 383-394
Author(s):  
Dmitry B. Barsukov ◽  
Alexei G. Baindurashvili ◽  
Pavel I. Bortulev ◽  
Vladimir E. Baskov ◽  
Ivan Y. Pozdnikin ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Femoral Component ◽  
Femoroacetabular Impingement ◽  
High Efficiency ◽  
Slipped Capital Femoral Epiphysis ◽  
Hip Dislocation ◽  
Surgical Interventions ◽  
Group 2 ◽  
Low Efficiency ◽  
Group 1

Background. The spatial relationship between the epiphysis and the acetabulum in slipped capital femoral epiphysis (SCFE) with severe chronic epiphysis displacement is restored by different corrective extra-articular femoral osteotomies and a standard Dunn procedure. Severe residual deformity of the femoral component of the joint with symptoms of femoroacetabular impingement and a large number of severe ischemic complications forced the surgeons to improve the technique of these surgical interventions. In particular, a modified Dunn procedure was proposed using a low traumatic surgical hip dislocation. However, the selection of surgical treatment in these patients remains a subject of discussion. Aim. This study aimed to improve the results of treatment in children with SCFE with severe chronic epiphysis displacement. Materials and methods. Data of preoperative and postoperative clinical and radiological studies of 40 patients (24 male and 16 female) aged 1215 years who were suffering from SCFE with severe chronic epiphysis displacement were analyzed. In all cases, on the lesion side, displacement was found in typical directions (posterior-downward or only posterior), and in the contralateral joint, the disease was still at its initial stage (pre-slip). In group 1 (n = 20 children), a corrective extra-articular femoral (anterior-rotational or rotational-valgus) osteotomy was performed according to the method we have proposed in 2011 [22], and in group 2 (n = 20 children), the modified Dunn procedure that strictly followed our technique was performed. The follow-up period after surgery in both groups ranged from 1 month to 2.5 years. Results. At 2.5 years after surgery, good anatomical and functional outcomes were observed only in 1 (12.5%) of 8 patients in group 1, while they were observed in 7 (87.5%) of 8 patients in group 2. Poor results were determined by residual epiphyseal displacement (from 22 to 28) and/or step-like transition of the anterior femoral neck surface to the head in 5 (62.5%) children in group 1 and by femoral head avascular necrosis (diagnosed in 6 months after surgery) in 1 (12.5%) child in group 2. Conclusion. The results allow us to make a preliminary conclusion about the high efficiency of the modified Dunn procedure and the low efficiency of the corrective extra-articular femoral osteotomy in SCFE with severe chronic displacement of the epiphysis. The modified Dunn procedure corrects the pronounced deformity of the femoral component of the affected joint and femoroacetabular impingement in the above-mentioned anatomical situations.

scholarly journals Neuropsychological development of children with biliary atresia after liver transplantation

2021 ◽  
Vol 23 (3) ◽  
pp. 66-72
Author(s):  
A. V. Syrkina ◽  
I. E. Pashkova ◽  
A. R. Monakhov ◽  
O. V. Silina ◽  
E. V. Chekletsova ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Surgical Treatment ◽  
Biliary Atresia ◽  
Psychomotor Development ◽  
Two Stage ◽  
Neuropsychological Development ◽  
One Stage ◽  
The Difference ◽  
Group 2 ◽  
Group 1

Background. In young children, the most common liver disease leading to transplantation is biliary atresia. Liver transplantation has fundamentally improved the survival rate of children with biliary atresia. Studies on developmental outcomes in children are mostly limited to small samples; there are no such studies in the Russian Federation.Objective: to determine the cognitive outcomes in children undergoing one-stage or two-stage surgical treatment of biliary atresia.Materials and Methods. 83 children were divided into groups: 36 children underwent transplantation without previous surgical interventions (group 1), 47 children underwent the Kasai palliative portoenterostomy (group 2). Inclusion criteria: 24 months of age or younger at the moment of transplantation, no medical history of neurological pathology. All children were examined before transplantation and at 1, 3, 6 and 12 months after liver transplantation. Psychomotor development was assessed using the Griffiths Psychomotor Development Scale for children under 24 months (translated by E.S. Keshishian), the Griffiths Intellectual Development Scale for children aged 2 to 8 years, and the Modified Checklist for Autism in Toddlers, Revised, for children 16-30 months old.Results. All children had developmental delays at the time of transplantation. Up to 50% of the children had signs of cachexia, with a shoulder circumference of less than 3 percentile. Only two children showed obvious hepatic encephalopathy in the form of depressed consciousness. After liver transplantation, 94% of group 1 children recovered their preoperative psychomotor development levels, and only 68% in group 2 made these gains. At 3 and 6 months after transplantation, about 80% of group 1 children showed normal psychomotor development, whereas in group 2, only 61% did. By 12 months after liver transplantation, the difference between the groups was more evident: 83.3% of group 1 children and only 53.2% of group 2 children were developing according to age. The difference between the groups was statistically significant (p < 0.05).Conclusion. Children who received one-stage treatment of biliary atresia and underwent liver transplantation have better neuropsychological development within a year after surgery than children with two-stage surgical treatment.

scholarly journals Can We Use the Silodosin as Second Line Treatment of Benign Prostate Hyperplasia?

2021 ◽  
Author(s):  
Bekir Voyvoda ◽  
Onur Memik ◽  
Onur Karslı ◽  
Murat Üstüner ◽  
Levent Özcan
Keyword(s):  
Surgical Treatment ◽  
Symptom Relief ◽  
Routine Practice ◽  
Prostate Hyperplasia ◽  
Blocker Therapy ◽  
Alpha Blocker ◽  
The Third ◽  
Voiding Symptoms ◽  
Group 2 ◽  
Group 1

Objective: We aimed to investigate the efficacy of silodosin in patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) refractory to previous α-adrenergic receptor (AR) blocker therapy. Materials and Methods: Patients who did not benefit from alpha-blocker therapy but avoided surgical treatment constitute the population of our study. Seventy-five patients were studied in each group; Group 1 was given 8 mg of silodosin, while Group 2 continued the previous alpha-blocker treatment. Results: The initial mean international prostate symptom score (IPSS) was calculated as 20.81±0.97 in Group 1, in the third month there was a decrease of 17.12±1.25 (p<0.05). No significant change was observed in Group 2. In addition, a significant decrease was observed in IPSS subscores (storage and voiding symptoms) in Group 1 compared to baseline at the third month. There was an improvement in residual urine in the silodosin group and no improvement in the other group. Conclusion: In patients with BPH who refuse surgical treatment and could not achieve adequate symptom relief with other α-blockers in routine practice, silodosin was found superior in terms of LUTS recovery. Silodosin is also an effective option in patients who cannot undergo surgical treatment due to comorbidities.

Application of femtolaser-assisted phacoemulsification in combined pathology of cataract and glaucoma

2021 ◽  
pp. 18-21
Author(s):  
A.P. Voznyuk ◽  
◽  
S.I. Anisimov ◽  
S.Y. Anisimova ◽  
L.L. Arutyunyan ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Biomechanical Properties ◽  
Mean Values ◽  
Long Term Follow Up ◽  
The Mean ◽  
Group 2 ◽  
Observation Period ◽  
Group 1

Purpose. To evaluate the efficacy and safety of femtolaser-assisted phacoemulsification in glaucomatous eyes in the long-term follow-up. Materials and methods. A retrospective analysis of the results of the surgical treatment of patients with combined cataract and glaucoma pathology was analyzed. The patients were divided into groups depending on the method of surgical intervention: 1) phacoemulsification with femtolaser support (26 eyes, 23 patients); 2) phacoemulsification (36 eyes, 30 patients); Results. Before surgery, there were no statistically significant differences in IOP and corneal hysteresis (СН) between groups 1 and 2. The mean values of IOP cc, IOP g and СН of group 1 before surgery were 22.7±6.1 mm Hg, 20.9±6.9 mm Hg, 8.5±1.6 mm Hg; 2 group – 22.9±8.7 mm Hg, 21.6±8.9 mm Hg, 8.9±1.6 mm Hg respectively. Average values of IOP cc, IOP g and CН 5 years after the surgical treatment in group 1 were 15.3±1.2 mm Hg, 14.4±3.4 mm Hg, 9.6±4.2 mm Hg; in group 2 – 18.0±4.2 mm Hg, 16.1±4.2 mm Hg, 8.8±2.2 mm Hg respectively. In both groups, stabilization of IOP and CH indices was noted, which remained throughout the entire observation period, which shows the normalization of the biomechanical properties of the corneoscleral membrane of the eye in the long-term postoperative period. Conclusion. Femtolaser accompaniment of phacoemulsification is an effective and safe method of cataract surgery for combined pathology. Key words: femtolaser, cataract, glaucoma, phacoemulsification.

Effect of Irradiation and Gentamycin on the Course of Experimental Peritonitis

1985 ◽  
Vol 1 (S1) ◽  
pp. 186-188
Author(s):  
T. Orlowski ◽  
S. Chabielski ◽  
A. Badowski ◽  
Z. Dumanski
Keyword(s):  
Surgical Treatment ◽  
Ionizing Radiation ◽  
Wistar Rats ◽  
Radiation Sickness ◽  
Simultaneous Action ◽  
Diffuse Peritonitis ◽  
Abdominal Organs ◽  
Male Wistar Rats ◽  
Group 2 ◽  
Group 1

The pathology of mixed injuries resulting from simultaneous action of several damaging factors on the organism is still insufficiently known. Peritonitis is the most frequent complication of injuries to the abdominal organs. Co-existence of peritonitis with radiation sickness impairs considerably the results of therapeutic management and prognosis. Surgical treatment is indicated in the latent period of radiation sickness or only in the period of recovery. In the case of diffuse peritonitis, the time of performing the operation is of essential importance for the prognosis. Thepurposeof the reportedinvestigationswas the study of the effect of ionizing radiation before exposure of the organism on the course of diffuse peritonitis and a trial of prolonging with an antibiotic the preliminary stage of the disease in which surgical treatment is effective. Investigations were carried out on 160 male Wistar rats weighing 250g on the average, divided into five groups. Group 1 served as control. In Group 2, the rats were only exposed to radiation.

Clinical study of thyroid cancer among a pediatric population born after Chernobyl (first report)

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 6069-6069
Author(s):  
M. B. Gorobeiko ◽  
O. S. Larin ◽  
S. M. Cherenko
Keyword(s):  
Thyroid Cancer ◽  
Surgical Treatment ◽  
Pediatric Population ◽  
Polluted Area ◽  
Follicular Variant ◽  
Regional Metastases ◽  
Radiation Induced ◽  
The Mean ◽  
Group 2 ◽  
Group 1

6069 Background: To evaluate the clinical and patologic results of surgical treatment of children born after Chernobyl and to compare these findings with well-known data of the group of patients who were children at the time of Chernobyl. To compare the clinical and pathologic features of thyroid cancer of children born after the Chernobyl versus those born prior to 1986. Methods: Comparison of clinical and pathologic result of surgical treatment of 141 patients born after Chernobyl (Group 1) and 589 patients (Group 2) aged 0–18 at the time of the disaster (1986) among the single institution clinical cohort within years 1995–2005. Results: In Group 1 there were 31 cancers (22%) vs. 243 (41%) in Group 2 (p<0.05 between Group 1 and Group 2). The rate of extrathyroid invasion was 69% vs. 36% (p<0.05 between Group 1 and Group 2). In Group 1, 17/21(80%) patients with extrathyroid invasion were found to have regional neck metastases (8 unilateral, 9 bilateral).The mean age in this subgroup was 13.4 ± 2.11 years but in the “benign subgroup” of Group 1 the mean age is 16.2 ± 0.77 years.In Group 2, 49/88 (55%) patients with extrathyroid invasion only had regional metastases. The mean age in this subgroup is 31.1 ± 4.7 years (p<0.05 between Group 1 and Group 2). We found cancer multifocality in 1 patient (3%, Group 1) vs. 55 (23%, Group 2).There were 19 cases (13.5%) of atypical adenomas in Group 1 vs. 46 (8%) in Group 2 (p<0.05 between Group 1 and Group 2). Histological types: solid follicular variant of papillary carcinoma (typical for radiation-induced children carcinomas with short latency) was found in 3 cases in Group 1 (9.5%) vs. 76 (31%) in the Group 2 (p<0.05 between Group 1 and Group 2). There was only one case of follicular thyroid cancer in Group 1 (3%) vs. 9% in Group 2. We did not find any relationship of cases of cancer in Group 1 to the Chernobyl-polluted area (only 3 patients − 10% from the nearest to Chernobyl regions) vs. 192 patients (80%) in Group 2 (p<0.05 between Group 1 and Group 2). Among patients with tumors of uncertain malignant potential 9 patients (6%) were from Chernobyl-polluted area vs.72% in Group 2 (p<0.05 between Group 1 and Group 2). Conclusions: Our data demonstrates higher likelihood of aggressive well-differentiated thyroid cancer among a pediatric population independently from Chernobyl irradiation and connected with another etiological factors of genesis of tumor.The solid-follicular variant of papillary cancer and multifocality are typical for radiation-induced carcinoma in children. No significant financial relationships to disclose.

scholarly journals Adrenal Incidentalomas: Should We Operate on Small Tumors in the Era of Laparoscopy?

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Michał Pędziwiatr ◽  
Michał Natkaniec ◽  
Mikhail Kisialeuski ◽  
Piotr Major ◽  
Maciej Matłok ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Operation Time ◽  
Adrenal Tumors ◽  
Estimated Blood Loss ◽  
Important Argument ◽  
Risk Of Malignancy ◽  
Potentially Malignant ◽  
Group 2 ◽  
Histopathological Results ◽  
Group 1

Tumor size smaller than 4 cm as an indication for surgical treatment of incidentaloma is still a subject of discussion. Our aim was the estimation of the incidence of malignancy and analysis of treatment outcomes in patients with incidentaloma smaller than 4 cm in comparison to bigger lesions. 132 patients who underwent laparoscopic adrenalectomy for nonsecreting tumors were divided into two groups: group 1 (55 pts., size < = 40 mm) and group 2 (77 pts., size > 40 mm). Operation parameters and histopathological results were analyzed. No differences in group characteristics, mean operation time, and estimated blood loss were noted. Complications in groups 1 and 2 occurred in 3.6% and 5.2% of patients, respectively (P=0.67). Malignancy in groups 1 and 2 was present in 1 and 6 patients, respectively (P=0.13). Potentially malignant lesions were identified in 4 patients in group 1 and 4 patients in group 2 (P=0.39). The results do not allow for straightforward recommendations for surgical treatment of smaller adrenal tumors. The safety of laparoscopy and minimal, but impossible to omit, risk of malignancy support decisions for surgery. On the other hand, the risk of malignancy in smaller adrenal tumors is lower than surgical complications, which provides an important argument against surgery.

scholarly journals Long-term results of surgical treatment of thyroid adenomas

2019 ◽  
Vol 100 (6) ◽  
pp. 892-897
Author(s):  
Stanislav Olegovich Artyukhin ◽  
Vladimir Georgievich Aristarhov ◽  
Denis Anatolyevich Puzin
Keyword(s):  
Surgical Treatment ◽  
Needle Aspiration ◽  
Long Term Results ◽  
Fine Needle ◽  
Thyroid Adenomas ◽  
Follicular Tumor ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Aim. To study the long-term results of surgical treatment of patients with thyroid adenomas. Methods. From 2004 to 2006, 667 patients with follicular adenomas of the thyroid gland, including 134 (20.1%) men and 533 (79.9%) women, were operated on in the surgical department №2 of city clinical hospital №11 of Ryazan. 3 groups of patients were defined: group 1 operated on for solitary adenomas of the thyroid gland, 103 patients, hemithyreoidectomy performed; group 2 operated on for multiple adenomas of the thyroid in both lobes, 101 patients, thyroidectomy performed; group 3 32 patients operated on for multiple adenomas of the thyroid in the same lobe, hemithyreoidectomy performed. Patients were examined 14 years after the surgery. Results. Hypothyroidism was diagnosed in: group 1 18 (17.5%) patients, group 2 101 (100%), group 3 0. All patients with hypothyroidism were compensated with hormone replacement therapy. Permanent hypoparathyroidism was diagnosed only in group 2 8 (4.8%) patients. Unilateral laryngeal paralysis was found in group 1 in 1 (0.9%) patient, group 2 in 2 (1.9%) patients, group 3 contained no such patients. Recurrence (node more than 1 cm according to ultrasound) was observed in group 1 in 12 (11.7%) patients; fine-needle aspiration found colloidal nodes in 8 (7.8%) patients (Bethesda II), in 4 (3.9%) follicular tumor (IV). Group 2 had no recurrences. In group 3 11 (34.3%) patients had recurrence; fine-needle aspiration found colloidal nodes in 1 (3.1%) patient (Bethesda II), in 10 (31.3%) follicular tumor (Bethesda IV). Conclusion. In solitary adenomas it is possible to perform organ-saving operations, which reduces the percentage of postoperative complications; in multiple adenomas, the optimal volume of surgery is thyroidectomy; when multiple adenomas are localized in one lobe, the chance of recurrence of the disease (31.3%) is high leading to re-surgery.

scholarly journals Protezinio infekcinio endokardito chirurginis gydymas: hospitalinis ir atokus išgyvenimas

2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Palmyra Semėnienė ◽  
Arimantas Grebelis ◽  
Rasa Joana Čypienė ◽  
Giedrė Nogienė ◽  
Gintaras Turkevičius
Keyword(s):  
Surgical Treatment ◽  
Survival Rate ◽  
Infective Endocarditis ◽  
Prosthetic Valve ◽  
Prosthetic Valve Endocarditis ◽  
Term Survival ◽  
Vilnius University ◽  
Group 2 ◽  
Group 1

Palmyra Semėnienė1, Arimantas Grebelis1, Rasa Joana Čypienė1, Giedrė Nogienė1, Gintaras Turkevičius21 Vilniaus universiteto ligoninės Santariškių klinikų Širdies chirurgijos centras,Santariškių g, 2, LT-08661 Vilnius2 Vilniaus universiteto ligoninės Santariškių klinikų Širdies chirurgijos centras,Santariškių g. 2, LT-08661 VilniusEl paštas: [email protected] Tikslas Darbo tikslas – išanalizuoti pacientų, operuotų dėl protezinio infekcinio endokardito (PIE), hospitalinio ir atokiojo laikotarpio rezultatus. Ligoniai ir metodai Retrospektyviai analizuoti 41 paciento, operuoto dėl PIE Vilniaus universiteto Širdies chirurgijos centre, pooperaciniai ir atokieji rezultatai. Analizuojamas laikotarpis nuo 2000 m. sausio 1 d. iki 2006 m. liepos 1 d. Vidutinis pacientų amžius 51,2 ± 10,1 metų. Pirma grupė – 20 pacientų – anksčiau sirgę infekciniu endokarditu (IE), antra grupė – 21 pacientas – anksčiau operuoti dėl reumatinės, įgimtos ar kitos etiologijos širdies vožtuvų patologijos. Rezultatai Hospitaliniu laikotarpiu mirė 10 pacientų (26,8%). Pirmos grupės hospitalinis mirštamumas buvo 25,0%, antros grupės – 28,6%. Hospitalinis pirmos grupės pacientų išgyvenimas buvo 75,0%, o antros – 71,4%. Praėjus 5 metams po operacijos pirmos grupės pacientų išgyvenimas buvo 59,9%, o antros – 53,5%, p > 0,005. Išvada Pacientų, operuotų dėl PIE, hospitalinis mirštamumas tebėra didelis. Nepastebėta, kad pacientų, anksčiau operuotų dėl infekcinio endokardito, pooperacinis ir atokus išgyvenimas po reoperacijos dėl PIE reikšmingai skirtųsi nuo nesirgusiųjų infekciniu endokarditu išgyvenimo. Pagrindiniai žodžiai: infekcinis endokarditas, protezinis infekcinis endokarditas Surgical treatment of prosthetic valve endocarditis: early and long-term outcome Palmyra Semėnienė1, Arimantas Grebelis1, Rasa Joana Čypienė1, Giedrė Nogienė1, Gintaras Turkevičius21 Vilnius University Cardial Surgery Centre, Santariškių str. 2, LT-08661 Vinius, Lithuania2 Vilnius University Hospital „Santariškių klinikos“, Cardial Surgery Centre,Santariškių str. 2, LT-08661 Vinius, LithuaniaE-mail: [email protected] Objective The objective of the present study was to examine in-hospital and long-term outcomes after surgical treatment of prosthetic valve endocarditis (PVE) between 1 January 2000 and 1 July 2006. Patients and methods Group 1 comprised 20 patients with previous infective endocarditis (IE) and group 2 – 21 patients without previous IE. The mean age was 51.2 ± 10.1 years. Results Ten patients (26.8%) died within 30 days post operation for PVE. In-hospital mortality of group 1 patients was 25% and of group 2 – 28.6%. The five-year survival rate is 59.9% (gr. 1) and 53.5% (gr. 2), p > 0.005. Conclusions Operation for PVE carries a high 30-day mortality and a reduced long-term survival. There was no evidence that previous infective endocarditis had an impact on survival rate in patients operated on for PVE. Key words: infective endocarditis, prosthetic valve endocarditis

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