Immunological Characteristics of Pollen and Tick-borne Sensitization in Bishkek Population

The article presents the results of a study of the prevalence of pollen allergy and allergies to house dust mites among Bishkek population in 2019. The examined patients, aged 4 to 60 years, were divided into groups according to the age periodization of a person. Identification of general and specific IgE antibodies was carried out using modern methods of laboratory diagnosis of the immunological profile. Linked Immunosorbent Assay options such as Chemiluminescence Immunoassay (CLIA) and Immunoblotting were used. The obtained results indicate a widespread sensitization of Bishkek population to pollen allergens, sensitization to house dust mite allergens is more pronounced in the form of a polyvalent allergy. There is also a tendency to increase the prevalence of allergic diseases among the country’s child population. Pollinosis occupy a leading place among allergic diseases in the country due to the fact that weeds prevail in the city’s natural vegetation, which are highly allergenic. Data on the incidence of allergic diseases in Kyrgyzstan, as well as abroad, do not reflect the true spread of allergies, because like most patients with mild forms of allergic diseases do not go to the doctor. Therefore, the early detection, prevention and treatment of allergic diseases is one of the most important issues of modern medicine and biology. It is necessary to create annual flowering calendars of allergenic plants. Round the clock biomonitoring of the air to monitor pollen and air disputes is necessary to inform patients with hay fever. Preventive measures for patients with sensitization to house dust mite allergens include the prevention of mass reproduction of mites, namely the reduction of dust and humidity in rooms.

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Parental Perspectives on the Implementation of House Dust Mite Avoidance Measures for Children with House Dust Mite Sensitization

Asthma Allergy Immunology ◽

10.21911/aai.581 ◽

2021 ◽

Vol 19 (3) ◽

pp. 125-135

Author(s):

Pınar Gür Çetinkaya ◽

Elif Soyak Aytekin ◽

Ayşegül Akarsu ◽

Ümit Murat Şahiner ◽

Bülent Enis Şekerel ◽

...

Keyword(s):

High School ◽

Middle School ◽

House Dust ◽

House Dust Mite ◽

Allergic Diseases ◽

House Dust Mites ◽

Dust Mite ◽

Associate's Degree ◽

Education Status ◽

Avoidance Measures

ABSTRACTObjective: The avoidance of house dust mite (HDM) is crucial in the management of HDM allergies. We aimed to demonstrate the implementation and perspective of the parents whose children had HDM allergy/sensitization to HDM avoidance measures. Materials and Methods: Parents of the patients with HDM sensitization were interviewed via telephone questionnaires.Results: One hundred and three patients with asthma (73.8%), allergic rhinitis (AR) (77.7%) and/or atopic dermatitis (AD) (29.1%) aged four to 18 years were included in the study. Seventy-one patients had multiple allergic diseases (68.9%). Of the parents, 39.8% fully adhered to HDM avoidance measures, and their education status was as follows: 41.5% illiterate/elementary/middle school, 31.7% high school, and 26.8% associate’s degree/university. In addition, 32.2% of the mothers who were partially adherent (n=62) were illiterate or had graduated from elementary/middle school, 33.9% had graduated from high school, and 33.9% had an associate’s degree or had graduated from university. Forty-one (39.8%) mothers were working, and most of them (61%) had graduated from university or had an associate’s degree. Nearly half of the mothers who were partially adherent to HDM measures were working (n=32). In the multivariate analysis, the risk factors for partial adherence to measures was to be a working mother [OR:4.072, 95%CI: 1.350-12.882, p=0.013] and to have the belief that the measures were useless [OR:4.886, 95%CI: 1.499-15.923, p=0.008]. However, no relationship was shown between adherence to the measures and the severity of AR or AD, asthma control status and having multiple allergic diseases.Conclusion: Full adherence to HDM avoidance measures was considerably dependent on the mothers’ working status and belief in the ineffectiveness of the measures whereas there was no relationship to the severity of allergic diseases. This study also revealed how the education status of the mothers affected the adherence to allergen avoidance measures in real life.Keywords: Children, Dermatophagoides pteronyssinus,Dermatophagoides farinae, house dust mites, avoidance measures, parents, pediatrics, questionnaire

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HOUSE DUST MITE ALLERGENS: FROM NATIVE EXTRACTS TO MODIFIED PREPARATIONS

Rossiiskii Allergologicheskii ZHurnal ◽

10.36691/rja1476 ◽

2021 ◽

Author(s):

Anna Vasilyeva ◽

Valentina M. Berzhets ◽

Nina S. Petrova ◽

Svetlana V. Khlgatian ◽

Stanislava Yu. Petrova ◽

...

Keyword(s):

House Dust ◽

Allergic Diseases ◽

Specific Ige ◽

Dermatophagoides Pteronyssinus ◽

House Dust Mites ◽

Dust Mites ◽

Binding Reaction ◽

Dust Mite ◽

Allergenic Activity ◽

Elisa Inhibition

The growth of allergic diseases dictates the need to develop new forms of therapeutic allergens with high immunogenic and low allergenic activity. For many years, our laboratory has been developing drugs for the diagnosis and treatment of house dust mites (HDM) allergies. The purpose of this study is to summarize the results of the five-year development of therapeutic preparations of HDM allergens. During this period, we obtained the following forms of therapeutic allergens: a granular sublingual dosage form of a mixed allergen from Dermatophagoides pteronyssinus (Der.p) and Dermatophagoides farinaе (Der.f) and a succinylated monomeric HDM allergoid Der.p. The physicochemical and immunobiological properties of the obtained preparations were studied by methods: electrophoresis in PAGE in the presence of SDS-sodium, micropoint immunoblot, ELISA, inhibition of the binding reaction of allergen-specific IgE in the sera of patients. The research results showed that the obtained preparations have a reduced allergenic and increased immunogenic activity in comparison with native extracts. The created forms of mite allergens can be further used to treat patients sensitized to HDM of the genus Dermatophagoides.

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TUNGAU DEBU RUMAH YANG DITEMUKAN DI KELURAHAN PERKAMIL KECAMATAN PAAL 2 KOTA MANADO

Jurnal e-Biomedik ◽

10.35790/ebm.1.2.2013.5471 ◽

2013 ◽

Vol 1 (2) ◽

Author(s):

Regina F. R. De Breving

Keyword(s):

House Dust ◽

House Dust Mite ◽

Random Sampling ◽

Simple Random Sampling ◽

Allergic Diseases ◽

House Dust Mites ◽

Living Room ◽

Dust Mites ◽

Dust Mite ◽

Descriptive Survey

Abstract: In house dust are a lot of house dust mites that found in damp houses, cotton mattress, pillows, bolsters, and other home furnishings. Sources of dust containing house dust mites are most in the bedroom especially cotton mattress. Data from distric health centers Paal 2 found that there are many people who suffer from asthma and allergic diseases, coupled with the humid air in Manado City to allow the development of house dust mites in the area. The purpose of this research is to determine the species and density of house dust mites in urban Perkamil Paal 2 districts Manado city. This research method is descriptive survey to obtain data on the species and density of house dust mites by simple random sampling method. The results found 5 species of house dust mites are Dermatophagoides spp, Acarus spp, Glycyphagus destructor, Tarsonemus spp and Cheyletus spp in bedrooms and living room. House dust mite densities obtained an average of 2,33 in bedroom and 2,07 in living room. The conclusion is house dust mite Dermatophagoides spp most commonly found in bedrooms and living room. Keywords: species, density, house dust mite Abstrak: Dalam debu rumah terdapat banyak tungau debu rumah yang ditemukan pada rumah yang lembab, kasur kapuk, bantal, guling serta perabot rumah yang lain. Sumber debu yang mengandung tungau debu rumah terbanyak adalah debu kamar tidur terutama debu di kasur kapuk. Dari data Puskesmas Kecamatan Paal 2 didapatkan bahwa masih banyak masyarakat yang menderita asma dan penyakit alergi, ditambah lagi dengan udara Kota Manado yang lembab sehingga memungkinkan terjadinya perkembangan tungau debu rumah di daerah tersebut. Tujuan penelitian ini untuk mengetahui jenis dan kepadatan tungau debu rumah di Kelurahan Perkamil Kecamatan Paal 2 Kota Manado. Metode penelitian ini secara survei deskriptif untuk mendapatkan data tentang jenis dan kepadatan tungau debu rumah dengan metode simple random sampling. Hasil yang didapat ditemukan 5 jenis tungau debu rumah yaitu Dermatophagoides spp, Acarus spp, Glycyphagus destructor, Tarsonemus spp dan Cheyletus spp di ruang tidur dan ruang tamu. Kepadatan tungau debu rumah didapatkan rata-rata 2,33 di ruang tidur dan 2,07 di ruang tamu. Kesimpulan yang diambil yaitu tungau debu rumah Dermatophagoides spp paling banyak ditemukan di ruang tidur maupun ruang tamu. Kata kunci: jenis, kepadatan, tungau debu rumah

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SURVEI PERILAKU MASYARAKAT TERHADAP POPULASI TUNGAU DEBU RUMAH DI KELURAHAN PERKAMIL KECAMATAN PAAL 2 KOTA MANADO

Jurnal e-Biomedik ◽

10.35790/ebm.1.2.2013.5478 ◽

2013 ◽

Vol 1 (2) ◽

Author(s):

Monalisa Rambing

Keyword(s):

House Dust ◽

House Dust Mite ◽

Public Attitudes ◽

Allergic Diseases ◽

Community Action ◽

House Dust Mites ◽

Dust Mites ◽

The Public ◽

Care Workers ◽

Dust Mite

Abstract: House dust mite are insects that can cause allergies in susceptible people. Population of dust mites in the home depends on factors such as the level of the sea, an area with a longer summer than rainy season, a variety of animals in the house, the house is dirty and a lot of dust, as well as the temperature and humidity of the area. Manado city has several of the factors. Purpose of the study is to investigate the people’s behavior of the population of house dust mites in Perkamil village sub-district of Paal 2 Manado city. Result obtained was 34,86% which shows that people’s knowledge about house dust mites are still lacking. The result of attitude is 97,09% indicated public attitudes towards the prevention and eradication of house dust mite is good. And result of the public action showed 75,96% of the community action efforts to prevent and eradicate house dust mites is enough. Necessary education from health care workers about house dust mites and allergic diseases, prevention and eradication, so that the knowledge that still low will be better and the action that will be good enough. Keywords : Behavior, Peoples, House Dust Mites Abstrak: Tungau debu rumah (TDR) adalah serangga yang dapat menyebabkan alergi pada orang yang rentan. Populasi tungau debu di dalam rumah bergantung pada faktor – faktor, seperti tinggi rendahnya rumah dari permukaan laut, daerah dengan musim panas yang lebih panjang dari musim hujan, adanya berbagai macam binatang di dalam rumah, rumah yang kotor dan banyak debu, serta suhu dan kelembaban daerah tersebut. Kota Manado memiliki beberapa faktor tersebut. Tujuan penelitian adalah untuk mengetahui perilaku masyarakat terhadap populasi tungau debu rumah di Kelurahan Perkamil Kecamatan Paal 2 Kota Manado. Hasil yang didapatkan adalah 34,86% menunjukkan pengetahuan masyarakat Kelurahan Perkamil mengenai Tungau Debu Rumah masih kurang. Untuk sikap didapatkan hasil 97,09% menunjukkan sikap masyarakat terhadap upaya pencegahan dan pemberantasan Tungau Debu Rumah sudah baik. Dan untuk tindakan masyarakat didapatkan hasil 75,96% menunjukkan tindakan masyarakat terhadap upaya pencegahan dan pemberantasan Tungau Debu Rumah sudah cukup. Perlu dilakukan penyuluhan dari petugas kesehatan tentang Tungau Debu Rumah dan penyakit Alergi, cara pencegahan dan pemberantasan, agar pengetahuan masih rendah akan menjadi lebih baik lagi dan tindakan masyarakat yang sudah cukup akan menjadi baik. Kata Kunci : Perilaku, Masyarakat, Tungau Debu Rumah

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Sensitivity in allergic asthmatic subjects towards house dust mite allergens

Systematic and Applied Acarology ◽

10.11158/saa.26.1.5 ◽

2021 ◽

Vol 26 (1) ◽

pp. 75-84

Author(s):

Amandeep Kaur Dhaliwal ◽

Devinder Singh ◽

Ramanpreet Kaur Randhawa ◽

Atinderpal Singh

Keyword(s):

Allergic Asthma ◽

House Dust ◽

House Dust Mite ◽

Specific Ige ◽

Mite Species ◽

House Dust Mites ◽

Total Serum ◽

Dust Mites ◽

Allergic Asthmatic ◽

Dust Mite

Asthma is a common problem that affects about 20 million peoples in India and can be often under-diagnosed or misdiagnosed. It can be allergic or non-allergic though the former type is more common and prevalent. Allergic asthma can be triggered by many allergens and house dust mites (HDM) are one of the common indoor allergens. The present study emphasizes the significance of house dust mites in allergic asthmatic subjects which is based on 115 asthmatic subjects in Punjab, India. For the quantification and the estimation of total serum Immunoglobulin E and HDM specific IgE, a mixture of 14 allergens and a mixture of two mite allergens viz. Dermatophagoides pteronyssinus and D. farinae were used respectively. Total and specific IgE levels were detected on ImmunoCAP Phadia 100. A statistically significant correlation between total and HDM specific IgE levels of 115 asthmatic subjects was found as compared to control group of 30 non-allergic individuals. The specific IgE levels of 54.78% subjects against the allergen of two mite species were found to be positive. Dust samples were taken from various localities of the houses to identify the diversity of house dust mites which were responsible for allergic asthma. Five common house dust mite species viz. D. pteronyssinus Trouessart, D. farinae Hughes, D. microceras Griffiths and Cunnington, D. aureliani Fain and Euroglyphus maynei Cooreman were identified from the dust. The present study observed that total IgE levels were higher with higher specific IgE levels against the mixture of two mite allergens viz. D. pteronyssinus and D. farinae in the blood serum. D. pteronyssinus was the most abundant and prevalent mite species followed by D. farinae. Therefore, present study concluded that HDM specific IgE levels against the mite allergen of D. pteronyssinus and D. farinae in the serum of allergic asthmatic subjects were found to be higher because of the higher prevalence of these two mites (D. pteronyssinus i.e. 69.80% and D. farinae i.e. 20.72%) in the house of allergic asthmatic subjects as compared to other identified mites.

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JENIS DAN KEPADATAN TUNGAU DEBU RUMAH PADA BEBERAPA HABITAT DI RUMAH PENDERITA PENYAKIT ALERGI

Jurnal e-Biomedik ◽

10.35790/ebm.3.1.2015.6734 ◽

2015 ◽

Vol 3 (1) ◽

Author(s):

Wiska F. Ponggalunggu ◽

Victor D. Pijoh ◽

Greta J. P. Wahongan

Keyword(s):

House Dust ◽

House Dust Mite ◽

Allergic Diseases ◽

Dermatophagoides Pteronyssinus ◽

House Dust Mites ◽

Dust Mites ◽

Dermatophagoides Farinae ◽

Cross Sectional ◽

Dust Mite ◽

Euroglyphus Maynei

Abstract. House dust mites are the most found allergens in homes scattered throughout the world that associated with allergic manifestations in the respiratory tract and skin, such as bronchial asthma, allergic rhinitis and atopic dermatitis. The most common house dust mite is from the family Pyroglyphidae, four of which have a close relationship with the incidence of allergy: Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermatophagoides microceras, and Euroglyphus maynei. This study aims to determine the type and density of house dust mites in several habitats in the homes of people with allergic diseases. This study is a descriptive study using cross-sectional method. Samples were dust in allergic patient’s home in Malalayang I, taken from three habitats, namely bed (mattress and bed linen), bedrooms floor and sofa, as many as 96 samples. Of the 96 samples, there are 60 samples positive of dust mites and 36 negative samples. This study found 157 mites (124 adults and 33 larvae mites). Of the 124 adult mites were identified, there are 122 from order Astigmata with the dominant species is Dermatophagoides pteronyssinus, and two others of the order Prostigmata. In each habitat that is in the bed (mattress and bed linen), bedrooms floor and sofa, Pyroglyphidae is the most prevalent.Keywords: house dust mite, allergiesAbstrak. Tungau debu rumah (TDR) adalah alergen dalam rumah terbanyak yang tersebar di seluruh dunia yang dikaitkan dengan manifestasi alergi pada saluran pernapasan dan kulit, seperti asma bronkial, rinitis alergi dan dermatitis atopik. TDR yang paling sering ditemukan adalah dari famili Pyroglyphidae, empat di antaranya memiliki hubungan yang erat dengan kejadian alergi: Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermatophagoides microceras, dan Euroglyphus maynei. Penelitian ini bertujuan untuk mengetahui jenis dan kepadatan tungau debu rumah pada beberapa habitat di rumah penderita penyakit alergi. Penelitian ini adalah penelitian deskriptif dengan menggunakan metode cross-sectional. Sampel penelitian adalah debu di rumah penderita alergi di Kelurahan Malalayang I yang diambil dari 3 habitat, yaitu tempat tidur (kasur dan sprei), lantai kamar tidur, dan sofa sebanyak 96 sampel. Dari 96 sampel, 60 sampel positif tungau debu dan 36 sampel negatif. Pada penelitian ini ditemukan 157 tungau (124 tungau dewasa dan 33 larva). Dari 124 tungau dewasa yang terindentifikasi, dari ordo Astigmata sebanyak 122 dengan spesies yang dominan adalah Dermatophagoides pteronyssinus, dan dua lainnya dari ordo Prostigmata. Pada masing-masing habitat yaitu di tempat tidur (kasur dan sprei), lantai kamar tidur dan sofa, famili Pyroglyphidae paling banyak ditemukan.Kata kunci: tungau debu rumah, alergi

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SURVEI PERILAKU MASYARAKAT TERHADAP POPULASI TUNGAU DEBU RUMAH DI KELURAHAN BITUNG KARANGRIA KECAMATAN TUMINTING KOTA MANADO

Jurnal e-Biomedik ◽

10.35790/ebm.2.1.2014.3652 ◽

2014 ◽

Vol 2 (1) ◽

Author(s):

Greis Emilia Tawurisi

Keyword(s):

House Dust ◽

House Dust Mite ◽

Health Workers ◽

Allergic Diseases ◽

Health Department ◽

House Dust Mites ◽

Local Health ◽

Dust Mites ◽

The Public ◽

Dust Mite

Abstract: House dust mites (HDM) is very small creatures and can not visible with the unaided eyes, found in the house dust and can causing allergic diseases. The existence of dust mites can not be separated from people's behavior about the house dust mite populations.The purpose of research is to know of the public behavior about the population House Dust Mites in the Bitung Karangria Village District of Tuminting Manado.The results obtained 34,86% are show that the cognition of the mites in Bitung Karangria Village is still deficient, and for attitude 97.83% are show that people have a good attitude, and for the action are obtained 82,44%, this show the attitude of the community is good.The cognition about house dust mitesis still less, and for the attitudes and actions of society is good. It takes counseling from health workers especially local health department about the house dust mite. Keywords: behavior of the public, House Dust Mites Abstrak: Tungau debu rumah (TDR) adalah mahluk yang sangat kecil dan tidak dapat dilihat dengan mata telanjang, ditemukan pada debu rumah dan dapat menyebabkan penyakit alergi. Keberadaan tungau debu rumah tidak terlepas dari perilaku masyarakat terhadap populasi tungau debu rumah tersebut. Tujuan penelitian adalah Mengetahui perilaku masyarakat terhadap populasi Tungau Debu Rumah di kelurahan Bitung karangria Kecamatan Tuminting kota Manado. Hasil yang didapatkan adalah 34,86% menunjukan pengetahuan masyarakat Kelurahan Bitungkarangria terhadap tungau debu rumah masi kurang, dan sikap didapatkan hasil 97,83% menunjukan bahwa sikap masyarakat sudah baik, serta untuk tindakan didapatkan hasil 82,44% ini menunjukan sikap masyarakat sudah baik. Pengetahuan masyarakat mengenai tungau debu rumah masi kurang, dan untuk sikap serta tindakan masyarakat sudah baik. Dibutuhkan penyuluhan dari petugas kesehatan kususnya dinas kesehatan setempat mengenai tungau debu rumah. Kata kunci: perilaku masyarakat, Tungau Debu Rumah

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Identifikasi Tungau Debu Rumah di Tempat Tinggal Pasien Dermatitis Atopik RSUD Petala Bumi Pekanbaru

Jurnal Ilmu Kedokteran ◽

10.26891/jik.v12i2.2018.89-94 ◽

2019 ◽

Vol 12 (2) ◽

pp. 89

Author(s):

Suri Dwi Lesmana ◽

Deon Pradana Putra ◽

Alida Widiawaty

Keyword(s):

Atopic Dermatitis ◽

House Dust ◽

House Dust Mite ◽

Sampling Technique ◽

Allergic Diseases ◽

House Dust Mites ◽

Dust Mites ◽

Hospital Design ◽

Consecutive Sampling ◽

Dust Mite

House dust mite have an important role as an allergens in allergic diseases such as atopic dermatitis. Atopic dermatitisis inflammation of the skin with itching, chronic and recurrent symptoms. The aim of this study was to find out thedescription of house dust mites in the house of patients at Petala Bumi Hospital. Design of study was a crosssectional.This study was occured from May-June 2018 in the Laboratory of Parasitology and involved 30 atopicdermatitis patients with consecutive sampling technique. Results is showed 100% of atopic dermatitis patients housewere positive for house dust mites, 63.3% of patients behaved badly in hygiene which affected degree of house dustmite spread. Conclusions of this study showed that a whole place of atopic dermatitis patients house was positive forhouse dust mite, most of patients behaved badly in hygiene which affected degree of house dust mite spread.

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