scholarly journals DIAGNOSTIC AND TREATMENT DIFFICULTIES OF SPOROTRICHOSIS

2021 ◽  
pp. 51-57
Author(s):  
L.V. Hrechanska ◽  
◽  
S.P. Ostapenko ◽  
P.V. Fedorych ◽  
◽  
...  
Keyword(s):  
Clinical Case ◽  
Sporothrix Schenckii ◽  
Antifungal Drugs ◽  
Alternative Methods ◽  
Dimorphic Fungus ◽  
Adequate Dose ◽  
Diagnostic Difficulties ◽  
Deep Mycosis ◽  
Methods Of Treatment

Introduction. Sporotrichosis is a deep mycosis caused by the dimorphic fungus Sporothrix schenckii and arises from traumatic inoculation of fungus conidia into damaged skin from plants and other organic material. The objective. In order to prevent diagnostic mistakes, which leads to a long-term and ineffective treatment we presented a clinical case of the sporotrichosis, a rare skin disease in our country, that arose in an elderly patient after a rose injury. Methods. The diagnosis of sporotrichosis of the skin was established by the clinical data, anamnesis and histologic examination. Results The impossibility of long-term administration of systemic antifungal drugs in an adequate dose in this case, required to find out an alternative methods of treatment without systemic side effects. The use of local radiation therapy in a patient with skin sporotrichosis led to a positive result in this clinical case. Conclusions. Diagnostic difficulties and the problems of the treatment require awareness of dermatovenereologists and use of alternative methods of treatment.

Twelve cases of glottic carcinoma in situ treated by radiotheraphy: an observation on clinical course versus response

1993 ◽  
Vol 107 (11) ◽  
pp. 1014-1016 ◽  
Author(s):  
J. P. Brooks ◽  
D. W. Morgan ◽  
J. Glaholm
Keyword(s):  
Carcinoma In Situ ◽  
Clinical Course ◽  
Alternative Methods ◽  
Glottic Carcinoma ◽  
Methods Of Treatment ◽  
Disease Free ◽  
Long Term Studies

AbstractCarcinoma in Situ (CIS) of the glottis is an uncommon and poorly understood condition with few, large, long- term studies. Twelve cases are presented which were treated with radiotherapy. At three-year follow-up all the patients are disease free and in 83 per cent the mucosa has returned to normal. The alternative methods of treatment are discussed.

scholarly journals Reducing the Global Burden of Depression

2014 ◽  
Vol 4 (1) ◽  
pp. 49
Author(s):  
Prabjyot Kaur Chahil
Keyword(s):  
Depressive Disorders ◽  
Cost Effective ◽  
Term Treatment ◽  
Alternative Methods ◽  
Global Burden ◽  
First Line ◽  
Depression Prevention ◽  
Long Term Treatment ◽  
Methods Of Treatment

<p>Depression is expected to be one of the leading causes of morbidity by 2020. Nonetheless, the current methods of treatment for depression may not be effective in reducing the global burden of this disease. Currently, pharmacotherapy represents the first line treatment for depressive disorders; however, many adverse effects of anti-depressants are often overlooked and their interference with body chemistry may not be ideal for long-term treatment.</p><p>In order to reduce the burden of disease of depression, methods of treatment such as counseling and therapy should be considered as alternatives to pharmacotherapy. Most importantly, these treatments reduce the occurrence of depression relapse, making them more effective in the long-term. In addition to alternative methods of treatment, depression prevention strategies should be prioritized. Not only is depression prevention the best solution therapeutically, but it is also the most cost-effective in reducing global morbidity. In order to implement these strategies, however, more evidence-based research on the prevention of depressive disorders is required.</p>

CLINICAL CASE OF LONG-TERM RESULTS OF KERATO-REFRACTIVE SURGERIES IN A PATIENT WITH A HIGH MYOPIA

2019 ◽  
Vol 21 (4) ◽  
pp. 14-16
Author(s):  
M.A. Frolov ◽  
◽  
P.A. Gonchar ◽  
V.A. Biletskaya ◽  
E.S. Belyaeva ◽  
...  
Keyword(s):  
High Myopia ◽  
Clinical Case ◽  
Long Term Results

СОХРАНЕНИЕ ПРИВЕРЖЕННОСТИ К ТЕРАПИИ КАК ГАРАНТИЯ ЭФФЕКТИВНОСТИ СЛИТ

2019 ◽  
Author(s):  
K.S. Pavlova ◽  
D.S. Mdinaradze
Keyword(s):  
Allergic Diseases ◽  
Atopic Asthma ◽  
National Guidelines ◽  
Allergen Specific Immunotherapy ◽  
Dose Dependent ◽  
Methods Of Treatment ◽  
Choice Of Therapy ◽  
Dose Dependent Effect ◽  
Reduced Adherence

По данным ВОЗ, рекомендации врача выполняют не более 50 пациентов. В конечном итоге это приводит к снижению или отсутствию эффекта от назначаемого лечения. В связи с этим во всех последних международных и национальных руководствах говорится о необходимости учета предпочтений пациента при выборе терапии. Аллерген-специфическая иммунотерапия (АСИТ) является одним из основных методов лечения аллергических заболеваний, таких как аллергический ринит, конъюнктивит и атопическая бронхиальная астма, обладает болезнь-модифицирующими свойствами и долгосрочным эффектом после окончания лечения. АСИТ относится к профилактическому и продолжительному методу (рекомендовано на протяжении не менее 3 лет), что часто является причиной снижения приверженности к терапии. В различных исследованиях подтвержден зависимый от дозы аллергена эффект АСИТ, а следовательно, изменение режимов или сокращение сроков терапии могут влиять на конечный результат. При недостаточной эффективности АСИТ необходимо в первую очередь рассматривать вероятность низкого комплаенса. Сублингвальная АСИТ (СЛИТ) требует от пациента высокой вовлеченности в процесс лечения. Задачей врача в данном случае становится повышение терапевтического сотрудничества как одного из важнейших факторов обеспечения эффективности СЛИТ. Основными способами в данном случае являются улучшение понимания пациентом цели терапии и регулярный контроль со стороны врача.According to WHO at last 50 of the patient dont follow doctors recommendations. Ultimately, this leads to a decrease or absence of the treatment effect. In this regard, all the latest international and national guidelines mention the need to take into account the patients preferences in the choice of therapy. Allergen-specific immunotherapy (AIT) is one of the main methods of treatment of allergic diseases such as allergic rhinitis, allergic conjunctivitis and atopic asthma, and has disease modifying properties and the long-term efficacy after stop treatment. AIT refers to a preventive and long-term method (recommended for at least 3 years), that is often the cause of reduced adherence to therapy. Various studies have confirmed the dose-dependent effect of AIT, and, consequently, changes in regimens or shortening of therapy may affect the end result. In case of insufficient effectiveness of AIT, the probability of low compliance should be considered first of all. Sublingual AIT (SLIT) requires the patient to be highly involved in the treatment process. The task of the doctor in this case is increasing therapeutic cooperation, as one of the most important factors to ensure the effectiveness of SLIT. The main methods in this case are to improve the patients understanding of the purpose of the therapy and regular monitoring by the doctor.

15 years experience with 615 homograft and autograft aortic valve replacements

1980 ◽  
Vol 3 (3) ◽  
pp. 168-172 ◽  
Author(s):  
W.H. Wain ◽  
R. Greco ◽  
A. Ignegeri ◽  
E. Bodnar ◽  
D.N. Ross
Keyword(s):  
Aortic Valve ◽  
Valve Replacement ◽  
Pulmonary Valve ◽  
Alternative Methods ◽  
Homograft Valve ◽  
Long Term Performance ◽  
Term Performance

Homograft valve replacement of the diseased aortic valve with a homologous aortic valve inserted in the sub-coronary position was first performed in July 1962 (Ross 1962). The procedure of transferring the patients autologous pulmonary valve to the aortic position has been used since 1967 (Ross 1967). The long term performance of homograft valves has not been regarded as satisfactory in some centres (Cope-land 1977, Anderson & Hancock 1977) whereas others have shown it to be an excellent valve replacement (Barratt-Boyes, 1977, Bodnar et al 1979). The differing experiences may be the results of alternative methods of sterilization, preservation and surgical insertion. This paper presents information on isolated aortic valve replacements with either homograft or autograft valves over a 15 year period.

‘Psychosis of civilization’: a colonial-situated diagnosis

2020 ◽  
pp. 0957154X2096806
Author(s):  
Marianna Scarfone
Keyword(s):  
Clinical Case ◽  
Inner Life ◽  
Differential Approach ◽  
Psychiatric Institutions ◽  
New Material

In the late 1930s, when colonial psychiatry was well established in the Maghreb, the diagnosis ‘psychosis of civilization’ appeared in some psychiatrists’ writings. Through the clinical case of a Libyan woman treated by the Italian psychiatrist Angelo Bravi in Tripoli, this article explores its emergence and its specificity in a differential approach, and highlights its main characteristics. The term applied to subjects poised between two worlds: incapable of becoming ‘like’ Europeans – a goal to which they seem to aspire – but too far from their ‘ancestral habits’ to revert for a quiet life. The visits of these subjects to colonial psychiatric institutions, provided valuable new material for psychiatrists: to see how colonization impacted inner life and to raise awareness of the long-term socio-political dangers.

COMPARATIVE ANALYSIS OF CLINICAL EFFICIENCY OF THE DRUG “BIO-DENT” IN BIOLOGICAL METHODS OF TREATMENT OF PULPITES BY THE METHOD OF INDIRECT COATING

2021 ◽  
Vol Special issue (1) ◽  
pp. 51-56
Author(s):  
Nigora Djuraeva ◽  
Keyword(s):  
Comparative Analysis ◽  
Portland Cement ◽  
Calcium Hydroxide ◽  
Dental Pulp ◽  
Mineral Trioxide Aggregate ◽  
Clinical Efficiency ◽  
Near Term ◽  
Biological Methods ◽  
Methods Of Treatment

The article presents the results of using a material based on the mineral trioxide unit “Bio-Dent”for the indirect coating of the pulp. It was found that there were no complaints from the use of domestic Portland cement both in the near term (98.8%) and inthe long term after treatment in comparison with materials based on calcium hydroxide (72.5%). Stabilization of the pulp electroexcitability indicators at the level of 10 mkA was noted with the use of the material based on MTA “Bio-Dent”as a medical liner for indirect pulp covering.Keywords: dental pulp,indirect pulp coating, calcium hydroxide, mineral trioxide aggregate, pulp electroexcitability.

scholarly journals Rolling technique for treatment of left displacement of the large colon in horses: 11 cases (2004-2009)

2013 ◽  
Vol 65 (2) ◽  
pp. 329-334 ◽  
Author(s):  
P.A. Canola ◽  
J.C. Lacerda Neto ◽  
J.C. Canola
Keyword(s):  
General Anesthesia ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
The Other ◽  
Safe Procedure ◽  
Emergency Procedures ◽  
Case Selection ◽  
Percutaneous Ultrasonography ◽  
Rectal Palpation

The left displacement of the large colon, a condition that commonly occurs in horses, has two clinical manifestations. Different treatments including medical treatment, rolling the horse under general anesthesia or surgical correction have been recommended. The diagnosis can often be made by rectal examination and confirmed by percutaneous ultrasonography. During the period between 2004 and 2009, 11 horses were treated for left displacement of the large colon by rolling the horses under general anesthesia, using a slightly different technique than the ones previously described. The clinical case selection was based on rectal palpation confirmed with ultrasonogram. Nine animals were successfully treated and two had to be submitted to surgery after three attempts of rolling. No short or long term complications were observed after the procedure. Only one animal had a recurrence of the clinical manifestation 10 months after the first treatment and was successfully rolled once again. Despite a bit different from the other rolling procedures, this also proved to be an effective procedure. Rolling a horse even when attempted more than once showed to be a safe procedure, however, we reinforce the need for special attention following the procedure in order to establish proper emergency procedures in case complications occur.

scholarly journals Accelerated partial breast irradiation by brachytherapy: present evidence and future developments

2020 ◽  
Vol 50 (7) ◽  
pp. 743-752
Author(s):  
Razvan Galalae ◽  
Jean-Michel Hannoun-Lévi
Keyword(s):  
Alternative Methods ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Radiation Toxicity ◽  
X Rays ◽  
Breast Irradiation ◽  
Patient Reported ◽  
Conventionally Fractionated ◽  
3D Crt

Abstract Accelerated partial breast irradiation (APBI) delivers a short course of adjuvant RT after breast conserving surgery to only a limited part of the breast where the tumor was located. This procedure requires expertise, good communication, and close collaboration between specialized surgeons and attending radiation oncologists with adequate intraoperative tumor bed clip marking. However, APBI offers several intrinsic benefits when compared with whole breast irradiation (WBIR) including reduced treatment time (1 versus 4–6 weeks) and better sparing of surrounding healthy tissues. The present publication reviews the APBI level 1-evidence provided with various radiation techniques supplemented by long-term experience obtained from large multi-institutional phase II studies. Additionally, it offers an outlook on recent research with ultra-short or single-fraction APBI courses and new brachytherapy sources. Mature data from three randomized controlled trials (RCTs) clearly prove the noninferiority of APBI with ‘only two techniques—1/MIBT (multicatheter interstitial brachytherapy) (two trials) and 2/intensity modulated radiotherapy (one trial)’—in terms of equivalent local control/overall survival to the previous standard ‘conventionally fractionated WBIR’. However, MIBT-APBI techniques were superior in both toxicity and patient-reported outcomes (PROs) versus WBIR at long-term follow-up. Currently, in RCT-setting, alternative APBI techniques such as intraoperative electrons, 50-kV x-rays and three-dimensional conformal external beam radiotherapy (3D-CRT) failed to demonstrate noninferiority to conventionally fractionated WBIR. However, 3D-CRT-APBI compared noninferior to hypo-fractionated WBIR in preventing ipsilateral breast tumor recurrence (randomized RAPID-trial) but was associated with a higher rate of late radiation toxicity. Ultimately, MIBT remains the only APBI modality with noninferior survival/superior toxicity/PROs at 10-years and therefore should be prioritized over alternative methods in patients with breast cancer considered at low-risk for local recurrence according to recent international guidelines.

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