scholarly journals Rolling technique for treatment of left displacement of the large colon in horses: 11 cases (2004-2009)

2013 ◽  
Vol 65 (2) ◽  
pp. 329-334 ◽  
Author(s):  
P.A. Canola ◽  
J.C. Lacerda Neto ◽  
J.C. Canola
Keyword(s):  
General Anesthesia ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
The Other ◽  
Safe Procedure ◽  
Emergency Procedures ◽  
Case Selection ◽  
Percutaneous Ultrasonography ◽  
Rectal Palpation

The left displacement of the large colon, a condition that commonly occurs in horses, has two clinical manifestations. Different treatments including medical treatment, rolling the horse under general anesthesia or surgical correction have been recommended. The diagnosis can often be made by rectal examination and confirmed by percutaneous ultrasonography. During the period between 2004 and 2009, 11 horses were treated for left displacement of the large colon by rolling the horses under general anesthesia, using a slightly different technique than the ones previously described. The clinical case selection was based on rectal palpation confirmed with ultrasonogram. Nine animals were successfully treated and two had to be submitted to surgery after three attempts of rolling. No short or long term complications were observed after the procedure. Only one animal had a recurrence of the clinical manifestation 10 months after the first treatment and was successfully rolled once again. Despite a bit different from the other rolling procedures, this also proved to be an effective procedure. Rolling a horse even when attempted more than once showed to be a safe procedure, however, we reinforce the need for special attention following the procedure in order to establish proper emergency procedures in case complications occur.

scholarly journals Hemisection: An alternative to extraction : A case report

2021 ◽  
Vol 6 (3) ◽  
pp. 128-131
Author(s):  
Deeksha Khurana ◽  
Charu Thanvi ◽  
Deepak Raisingani ◽  
Prasad B. Ashwini
Keyword(s):  
Case Report ◽  
Young Patient ◽  
Treatment Option ◽  
Critical Factor ◽  
The Other ◽  
Case Selection ◽  
Mandibular Molar

Hemisection is sectioning of multi-rooted teeth followed by removal of compromised root along with its associated crown portion and leaving the healthy root (with crown) intact. This treatment option can be considered when caries, resorption, perforation, or periodontal damage is restricted to one root while the other root is relatively healthy. The most critical factor determiningthe long term success in such cases is the appropriate case selection. This case report describes a case of hemisectionof a mandibular molar followed by adequate restoration in a young patient.

scholarly journals A complex case of diagnosis of Conn’s syndrome

2020 ◽  
Vol 28 (1) ◽  
pp. 67-72
Author(s):  
Grigory A. Ignatenko ◽  
Ilya S. Grekov ◽  
Marina V. Grushina ◽  
Anna V. Dubovyk
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Clinical Case ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
The Other ◽  
Primary Hyperaldosteronism ◽  
Complex Case ◽  
Conn’S Syndrome ◽  
The Given

The primary hyperaldosteronism also known as Conns syndrome, is a rarely diagnosed disease that commonly runs under a mask of ischemic heart disease and the primary arteria hypertension (AH). Nevertheless, the incidence of the given pathology among all patients with AH makes almost 17%. On the other hand, the absence of specific clinical manifestations of the disease makes its timely and correct diagnosis difficult which is fraught with serious complications. In the article a clinical case of Conns syndrome and peculiarities of its diagnosis are described.

Development of sulfasalazine-associated drug-induced lupus erythematosus in patient with rheumatoid arthritis (clinical case)

2021 ◽  
pp. 26-29
Author(s):  
A. N. Kovshik ◽  
E. P. Kiseleva ◽  
N. G. Klyukvina ◽  
G. V. Lukina
Keyword(s):  
Rheumatoid Arthritis ◽  
Lupus Erythematosus ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
New Drugs ◽  
Drug Induced ◽  
Reliable Diagnosis ◽  
Term Administration ◽  
Lupus Syndrome

Drug-induced lupus syndrome (DLS) is a rare adverse event with a variety of drugs. More than a hundred of drugs are known that can cause the development of DLS, and this list is growing as new drugs appear. Physicians of any specialty can face such complications of therapy and should be aware of this pathology. The article presents an analysis of a clinical case of DLS development against the background of long-term administration of sulfasalazine in a patient with a reliable diagnosis of rheumatoid arthritis, as well as a literature review, which includes data on the prevalence, drug groups, clinical manifestations, diagnosis and treatment of this pathology.

scholarly journals Regression of Liquorodynamic Disorders and Ventriculoperitoneal Shunt Overdrain Syndrome Clinic in a Patient After Severe Brain Injury with Posttraumatic Hydrocephalus and a Giant Cranial Bones Defect After Cranioplasty: Case Report

2020 ◽  
Vol 2 (3) ◽  
pp. 263-272
Author(s):  
Alexey N. Vorobyev ◽  
Inessa G. Shchelkunova ◽  
Dmitrii V. Levin ◽  
Oleg B. Lukyanec ◽  
Alexandr A. Shaybak ◽  
...  
Keyword(s):  
Brain Injury ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Brain Structures ◽  
Cranial Vault ◽  
Shunt System ◽  
Cranial Defect ◽  
Post Traumatic ◽  
Relationship Of

Introduction. The frequency of post-traumatic hydrocephalus is 3.9%. The incidence of post-traumatic defects of the skull is 10.46 per 100,000 per year. Overdrain syndrome occurs in 1012% of cases in patients with long-term ventricular shunting. The presence of a cranial defect causes a violation of blood flow and cerebrospinal fluid dynamics in the area of the defect, a displacement of brain structures under the influence of gravity and atmospheric pressure, which can cause a deterioration in the patients condition and a significant slowdown in recovery after a severe head injury. Both craniotomy syndrome and excessive shunting can impede the verticalization and rehabilitation of patients with post-traumatic hydrocephalus and post-traumatic defects of the bones of the cranial vault. Description of the clinical case. Clinical case demonstrates an example of a differential approach and an algorithm for deciding on surgical treatment in a patient with post-traumatic hydrocephalus and cranial bones defect in case of deterioration during attempts at verticalization in a complex of rehabilitation measures. Conclusion. The clinical manifestations of trephine skull syndrome and syndrome of shunt overdrain in the patient after severe traumatic brain injury combines post-traumatic hydrocephalus, may be similar. And not always, as demonstrated in this clinical case, narrowed ventricles and the relationship of deterioration to verticalization should be interpreted as a syndrome of excessive drainage of the shunt system. The plastic surgery of the defect of the bones of the cranial vault performed in this case made it possible to improve the patients condition and regress symptoms.

scholarly journals A clinical case of congenital hyperinsulinism in an early child

2020 ◽  
Vol 11 (3) ◽  
pp. 54-59
Author(s):  
S. B. Berezhansky ◽  
A. A. Afonin ◽  
E. A. Papsheva ◽  
N. N. Vostrykh ◽  
G. A. Galkina ◽  
...  
Keyword(s):  
Clinical Case ◽  
Severe Disease ◽  
Clinical Manifestations ◽  
Heterozygous Mutation ◽  
Congenital Hyperinsulinism ◽  
Early Child ◽  
Wide Range ◽  
Diffuse Form ◽  
Long Term Prognosis

A clinical case of congenital hyperinsulinism, diffuse form, pharmacoresistant course (heterozygous mutation of p. 1361 1363 dup CGG in the GCK gene) in an early child is presented as an example of an orphan severe disease with an extremely unfavorable course and a probability of deterioration of the long-term prognosis. The goal was to highlight the clinical manifestations, course options, and complexity of treatment of this pathology to a wide range of doctors of different specialties in the field of Pediatrics in terms of improving the quality and timeliness of diagnosis, reducing the number of complications with the formation of irreparable consequences. Attention is drawn to the most severe course of hypoglycemic conditions in the early neonatal period, the dependence of the formation of a pronounced neurological deficit on the degree and duration of hypoglycemia, which emphasizes the importance of their timely correction to preserve the quality of life of this contingent of children.

Skin

2019 ◽  
pp. 257-260
Author(s):  
Robin D. Clark ◽  
Cynthia J. Curry
Keyword(s):  
Clinical Case ◽  
Ectodermal Dysplasia ◽  
The Other ◽  
Sweat Glands ◽  
Hypohidrotic Ectodermal Dysplasia ◽  
Case Presentation ◽  
Pathogenic Variants ◽  
Ectodermal Dysplasias ◽  
Dental Management

This chapter reviews the various types of congenital ectodermal dysplasias (ED). These present variably with involvement of skin, teeth, sweat glands, hair, and nails. In the newborn period ED can resemble ichthyosis with erythema and scaling. X-lLinked hypohidrotic ectodermal dysplasia is the most common form and may affect girls as well as boys. This can cause infant overheating with serious sequelae. Long term dental management is needed for this disorder as well as for most of the other ED’s. Several ED syndromes involve immunodeficiency. Several allelic rare multiple anomaly ED syndromes are caused by pathogenic variants in TP63. The clinical case presentation features an infant with autosomal recessive hypohidrotic ectodermal dysplasia.

scholarly journals Secondary hypokalemic myoplegias

2019 ◽  
Vol 11 (3) ◽  
pp. 52-56
Author(s):  
T. G. Sakovets ◽  
E. I. Bogdanov
Keyword(s):  
Pregnant Women ◽  
Neuromuscular Disorders ◽  
Clinical Manifestations ◽  
Diagnostic Algorithm ◽  
The Other ◽  
Adrenal Tumors ◽  
Electrolyte Disorders ◽  
Endocrine Disease ◽  
Blood Potassium

Objective: to investigate the features of clinical manifestations and course of secondary hypokalemic myoplegia (SHM) of various etiologies.Patients and methods. The investigation enrolled 10 patients with SHM. The patients' mean age was 39.5±16.2 years. The cause of SHM was hyperaldosteronism in 3 cases, thyrotoxicosis in 1, nontraumatic rhabdomyolysis in 2, and severe toxicosis and massive obstetric hemorrhage in 4.Results and discussion. The blood potassium level difference between days 7 and 1 of hospitalization in patients with hyperaldosteronism and thyrotoxicosis was 2.2±0.4 mmol/l; this indicator in the other patients was less (1.6±0.8 mmol/l). The dynamics of an increase in the blood potassium concentrations during the 7 days differed significantly in 4 pregnant women who had undergone a cesarean section for placental abruption, antenatal fetal death, or their severe toxicosis with suddenly developed neuromuscular disorders (2.1±0.8 mmol/l), and in other patients with SHM (1.4±0.2 mmol/l). SHM in Conn's syndrome and thyrotoxicosis was characterized by long-term (11.8±3.6-day) neuromuscular disorders, while in SHM of another etiology, there were shorter (5.8±4-day) muscle weakness episodes (p<0.05). The SHM duration was recorded to be shorter in 4 pregnant women (4.3±4 days) than that in the other patients (10.3±2.9 days) (p<0.05). In nontraumatic rhabdomyolysis, the duration of hypokalemic paralysis (HP) was significantly longer (9±1.4 days) than in pregnancy (4.3±3.9 days). The episodes of HP in thyrotoxicosis and aldosteroma turned out to be longer (495.8±331.5 days) (p<0.05) than those in the presence of electrolyte changes in pregnant women and in rhabdomyolysis (14±5.7 days). In patients without adrenal tumors, thyrotoxicosis, the SHM periods requiring urgent hospitalization were more prolonged in nontraumatic rhabdomyolysis (30±8.5 days) (p<0.05) than those in the presence with electrolyte disorders in pregnant women (11.2±3.7 days).Conclusion. The differential diagnostic algorithm for examining patients with acute flaccid paralysis of various etiologies due to hypokalemia has not been well elaborated, especially in endocrine disease and rhabdomyolysis. The differences in the rate of hypokalemia reversal in hyperaldosteronism, thyrotoxicosis, and rhabdomyolysis are likely to be associated with the multifactorial etiology of SHM. An incorrect assessment of the etiology of SHM is a common reason for its late diagnosis and inadequate treatment.

scholarly journals Dirofilariasis of the pleura

2020 ◽  
pp. 122-127
Author(s):  
G. V. Tishchenko ◽  
A. I. Shalyga
Keyword(s):  
Histological Examination ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Granulomatous Inflammation ◽  
Human Tissues ◽  
Internal Organs ◽  
Slow Development

Dirofilariasis is the most common transmissible zoonotic nematodosis in Europe, whose clinical manifestations are caused by the migration of immature helminths through human tissues or internal organs. Clinically, it is characterized by slow development and a long-term course, and morphologically — by chronic granulomatous inflammation, often with microabscess.The work presents the description of a clinical case of dirofilariasis of the pleura, the diagnosis of which was performed only at the stage of the histological examination of the surgical material.

Surgical reconstruction for unilateral iliac artery lesions in patients younger than 50 years

VASA ◽  
2011 ◽  
Vol 40 (6) ◽  
pp. 474-481 ◽  
Author(s):  
Radak ◽  
Babic ◽  
Ilijevski ◽  
Jocic ◽  
Aleksic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Limb Salvage ◽  
Iliac Artery ◽  
Graft Patency ◽  
Long Term Results ◽  
Surgical Reconstruction ◽  
Safe Procedure ◽  
Term Survival

Background: To evaluate safety, short and long-term graft patency, clinical success rates, and factors associated with patency, limb salvage and mortality after surgical reconstruction in patients younger than 50 years of age who had undergone unilateral iliac artery bypass surgery. Patients and methods: From January 2000 to January 2010, 65 consecutive reconstructive vascular operations were performed in 22 women and 43 men of age < 50 years with unilateral iliac atherosclerotic lesions and claudication or chronic limb ischemia. All patients were followed at 1, 3, 6, and 12 months after surgery and every 6 months thereafter. Results: There was in-hospital vascular graft thrombosis in four (6.1 %) patients. No in-hospital deaths occurred. Median follow-up was 49.6 ± 33 months. Primary patency rates at 1-, 3-, 5-, and 10-year were 92.2 %, 85.6 %, 73.6 %, and 56.5 %, respectively. Seven patients passed away during follow-up of which four patients due to coronary artery disease, two patients due to cerebrovascular disease and one patient due to malignancy. Limb salvage rate after 1-, 3-, 5-, and 10-year follow-up was 100 %, 100 %, 96.3 %, and 91.2 %, respectively. Cox regression analysis including age, sex, risk factors for vascular disease, indication for treatment, preoperative ABI, lesion length, graft diameter and type of pre-procedural lesion (stenosis/occlusion), showed that only age (beta - 0.281, expected beta 0.755, p = 0.007) and presence of diabetes mellitus during index surgery (beta - 1.292, expected beta 0.275, p = 0.026) were found to be significant predictors of diminishing graft patency during the follow-up. Presence of diabetes mellitus during index surgery (beta - 1.246, expected beta 0.291, p = 0.034) was the only variable predicting mortality. Conclusions: Surgical treatment for unilateral iliac lesions in patients with premature atherosclerosis is a safe procedure with a low operative risk and acceptable long-term results. Diabetes mellitus and age at index surgery are predictive for low graft patency. Presence of diabetes is associated with decreased long-term survival.

Radioimmunotherapy for treatment of acute myeloid leukaemia and myelodysplastic syndrome

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Primary Tumour ◽  
The Other ◽  
Haematopoietic Stem Cell ◽  
Other Hand ◽  
Primary Reduction ◽  
The One ◽  
Acute Myeloid

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.

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