scholarly journals A Review on Nanosuspensionspromising Drug Delivery Strategy.

2012 ◽  
Vol 3 (1) ◽  
pp. 764-776 ◽  
Author(s):  
Toshi Chaurasia . ◽  
Divya Singh . ◽  
Nimisha . ◽  
Dipti Srivastava .
Keyword(s):  
Drug Delivery ◽  
Delivery Strategy

Abstract 6251: Blood brain barrier opening by TTFields: a future CNS drug delivery strategy

2020 ◽  
Author(s):  
Ellaine Salvador ◽  
Almuth F. Kessler ◽  
Julia Hörmann ◽  
Malgorzata Burek ◽  
Catherine T. Brami ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Delivery Strategy ◽  
Cns Drug Delivery ◽  
Blood Brain ◽  
Barrier Opening ◽  
Blood Brain Barrier Opening

scholarly journals A New Brain Drug Delivery Strategy: Focused Ultrasound-Enhanced Intranasal Drug Delivery

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e108880 ◽  
Author(s):  
Hong Chen ◽  
Cherry C. Chen ◽  
Camilo Acosta ◽  
Shih-Ying Wu ◽  
Tao Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Focused Ultrasound ◽  
Delivery Strategy ◽  
Intranasal Drug Delivery ◽  
Brain Drug Delivery

scholarly journals A targeted delivery strategy for the development of potent trypanocides

2017 ◽  
Vol 53 (62) ◽  
pp. 8735-8738 ◽  
Author(s):  
Heeren M. Gordhan ◽  
Jillian E. Milanes ◽  
Yijian Qiu ◽  
Jennifer E. Golden ◽  
Kenneth A. Christensen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Trypanosoma Brucei ◽  
Causative Agent ◽  
Targeted Delivery ◽  
Sleeping Sickness ◽  
African Sleeping Sickness ◽  
Delivery Strategy ◽  
New Drug

A new drug delivery strategy was investigated for the development of potent anti-parasitic compounds againstTrypanosoma brucei, the causative agent of African sleeping sickness.

Clinical Perspective of Electrospun Nanofibers as a Drug Delivery Strategy for Regenerative Endodontics

2016 ◽  
Vol 3 (3) ◽  
pp. 209-220 ◽  
Author(s):  
Maria T. P. Albuquerque ◽  
Juliana Y. Nagata ◽  
Anibal R. Diogenes ◽  
Asma A. Azabi ◽  
Richard L. Gregory ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Electrospun Nanofibers ◽  
Clinical Perspective ◽  
Delivery Strategy ◽  
Regenerative Endodontics

Malaria parasite transporters as a drug-delivery strategy

2005 ◽  
Vol 21 (7) ◽  
pp. 299-301 ◽  
Author(s):  
Giancarlo A. Biagini ◽  
Stephen A. Ward ◽  
Patrick G. Bray
Keyword(s):  
Drug Delivery ◽  
Malaria Parasite ◽  
Delivery Strategy

Bioreducible Pro-drug Inhibitors of Enolase

2020 ◽  
Author(s):  
Victoria Yan ◽  
Kristine Yang ◽  
Elliot Ballato ◽  
Kenisha Arthur ◽  
Dimitra Georgiou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Robust Stability ◽  
Biological Fluids ◽  
Tumor Hypoxia ◽  
Proof Of Concept ◽  
Delivery Strategy ◽  
Hypoxic Conditions

Glycolysis inhibition remains aspirational in cancer therapy. We recently described a promising phosphonate inhibitor of Enolase for cancers harboring deletions in ENO1. Here, we describe the application of nitroheterocycle pro-drugs capitalizing on tumor hypoxia. These bioreducible pro-drugs exhibit up to 14-fold greater potency under hypoxic conditions compared to normoxia and exhibit robust stability in biological fluids. Our work provides strong proof-of-concept for using bioreduction as a pro-drug delivery strategy in the context of Enolase inhibition.

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