scholarly journals Solventless Microextration Techniques for Pharmaceutical Analysis: The Greener Solution

2022 ◽  
Vol 9 ◽  
Author(s):  
Heba Mohamed
Keyword(s):  
Solid Phase ◽  
Sample Volume ◽  
Stir Bar Sorptive Extraction ◽  
Sorptive Extraction ◽  
Time Minimization ◽  
Microextraction Techniques ◽  
Packed Sorbent ◽  
As Solid Phase ◽  
Sample Volume Requirement ◽  
Made In

Extensive efforts have been made in the last decades to simplify the holistic sample preparation process. The idea of maximizing the extraction efficiency along with the reduction of extraction time, minimization/elimination of hazardous solvents, and miniaturization of the extraction device, eliminating sample pre- and posttreatment steps and reducing the sample volume requirement is always the goal for an analyst as it ensures the method’s congruency with the green analytical chemistry (GAC) principles and steps toward sustainability. In this context, the microextraction techniques such as solid-phase microextraction (SPME), stir bar sorptive extraction (SBSE), microextraction by packed sorbent (MEPS), fabric phase sorptive extraction (FPSE), in-tube extraction dynamic headspace (ITEX-DHS), and PAL SPME Arrow are being very active areas of research. To help transition into wider applications, the new solventless microextraction techniques have to be commercialized, automated, and validated, and their operating principles to be anchored to theory. In this work, the benefits and drawbacks of the advanced microextraction techniques will be discussed and compared, together with their applicability to the analysis of pharmaceuticals in different matrices.

Recent Trends in the Development of Green Microextraction Techniques for the Determination of Hazardous Organic Compounds in Wine

2019 ◽  
Vol 15 (7) ◽  
pp. 788-800 ◽  
Author(s):  
Natasa P. Kalogiouri ◽  
Victoria F. Samanidou
Keyword(s):  
Sample Preparation ◽  
Solid Phase Extraction ◽  
Organic Compounds ◽  
Method Development ◽  
Solid Phase ◽  
Stir Bar Sorptive Extraction ◽  
Phase Extraction ◽  
Microextraction Techniques ◽  
Hazardous Organic Compounds

Background:The sample preparation is the most crucial step in the analytical method development. Taking this into account, it is easily understood why the domain of sample preparation prior to detection is rapidly developing. Following the modern trends towards the automation, miniaturization, simplification and minimization of organic solvents and sample volumes, green microextraction techniques witness rapid growth in the field of food quality and safety. In a globalized market, it is essential to face the consumers need and develop analytical methods that guarantee the quality of food products and beverages. The strive for the accurate determination of organic hazards in a famous and appreciated alcoholic beverage like wine has necessitated the development of microextraction techniques.Objective:The objective of this review is to summarize all the recent microextraction methodologies, including solid phase extraction (SPE), solid phase microextraction (SPME), liquid-phase microextraction (LPME), dispersive liquid-liquid microextraction (DLLME), stir bar sorptive extraction (SBSE), matrix solid-phase dispersion (MSPD), single-drop microextraction (SDME) and dispersive solid phase extraction (DSPE) that were developed for the determination of hazardous organic compounds (pesticides, mycotoxins, colorants, biogenic amines, off-flavors) in wine. The analytical performance of the techniques is evaluated and their advantages and limitations are discussed.Conclusion:An extensive investigation of these techniques remains vital through the development of novel strategies and the implication of new materials that could upgrade the selectivity for the extraction of target analytes.

Technological Developments in the Determination of Emerging Contaminants in Water

2020 ◽  
pp. 81-108
Author(s):  
Magali Kemmerich
Keyword(s):  
Emerging Contaminants ◽  
Solid Phase ◽  
Food Additives ◽  
Stir Bar Sorptive Extraction ◽  
Sorptive Extraction ◽  
Low Concentrations ◽  
Gas And Liquid Chromatography ◽  
Technological Developments ◽  
Dispersive Liquid Liquid Microextraction

Emerging contaminants (ECs), which constitute a group of chemicals, such as personal care products, food additives, and endocrine disruptors, are not commonly monitored and have the potential to cause adverse effects on the environment and humans. In water, even at low concentrations, they pose risks to environmental health. Several technologies have been developed to determine these compounds; the most common ones are liquid-liquid extraction (LLE), solid-phase extraction (SPE), solid-phase microextraction (SPME), stir-bar sorptive extraction (SBSE), and dispersive liquid-liquid microextraction (DLLME) with analysis by gas and liquid chromatography (GC and LC) coupled to mass spectrometry (MS). This chapter analyzes these methodologies and highlights their possibilities and limitations and compiles the most recent advances in this field.

Molecularly Imprinted Polymers for the Analysis of Environmental Estrogen Bisphenol A

2014 ◽  
Vol 894 ◽  
pp. 143-148 ◽  
Author(s):  
Zhi Gang Xu
Keyword(s):  
Sample Preparation ◽  
Bisphenol A ◽  
Solid Phase ◽  
Selective Adsorption ◽  
Membrane Extraction ◽  
Stir Bar Sorptive Extraction ◽  
Molecularly Imprinted ◽  
Sorptive Extraction ◽  
Molecularly Imprinted Membrane ◽  
Preparation Techniques

Molecularly imprinted polymer (MIP) has the characteristics of predetermination, specific recognition and practicability. It can eliminate the interference of complicated matrix. It has been widely used as selective adsorption material in sample preparation. Bisphenol A is a common endocrine disruptor in environment. Its toxic effects and analysis have attracted widespread concern. In this paper, the molecularly imprinted sample preparation techniques for bisphenol A were comprehensively reported, including molecularly imprinted microspheres extraction, molecularly imprinted solid phase extraction, molecularly imprinted solid phase microextraction, molecularly imprinted stir bar sorptive extraction and molecularly imprinted membrane extraction. Moreover, the trends of BPA-molecularly imprinted techniques are prospected.

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