scholarly journals Chronic Obstructive Pulmonary Disease Is Associated With Decreased Quality of Life in Bronchiectasis Patients: Findings From the KMBARC Registry

2021 ◽  
Vol 8 ◽  
Author(s):  
Sang Hyuk Kim ◽  
Changhwan Kim ◽  
Ina Jeong ◽  
Seung Jun Lee ◽  
Tae Hyung Kim ◽  
...  

Most studies have evaluated the impact of non-cystic fibrosis bronchiectasis (hereafter referred to as bronchiectasis) on quality of life (QoL) in patients with chronic obstructive pulmonary disease (COPD) using COPD cohorts. Accordingly, the impact of COPD on QoL in patients with bronchiectasis is not well-elucidated. We used the Korean Multicenter Bronchiectasis Audit and Research Collaboration (KMBARC) registry between August 2018 and December 2019, a prospective observational cohort that enrolled patients with bronchiectasis in Korea. We evaluated co-occurrence exposure to COPD in bronchiectasis patients, and the primary outcome was QoL according to the Bronchiectasis Health Questionnaire (BHQ). We also investigated factors associated with decreased QoL, defined as the lowest quartile of the total BHQ score. Of 598 patients with bronchiectasis, 372 (62.2%) had COPD. Bronchiectasis patients with COPD had a significantly lower total BHQ score compared with those without COPD [median = 63.1 (interquartile range: 54.8–68.6) vs. 64.8 (57.4–70.8), p = 0.020]. Multivariable analysis revealed that dyspnea [adjusted odds ratio (aOR) = 3.21, 95% confidence interval (CI) = 1.21–8.60], depression (aOR = 1.28, 95% CI = 1.16–1.44), and fatigue (aOR = 1.05, 95% CI = 1.01–1.09) were significantly associated with decreased QoL in bronchiectasis patients with COPD. In conclusion, bronchiectasis patients with COPD had significantly decreased QoL than patients without COPD. In bronchiectasis patients with COPD, dyspnea, depression, and fatigue were associated with decreased QoL.

Author(s):  
Kavita S. Joshi ◽  
Prasad R. Amrale ◽  
Sagar S. Ahire

Background: Chronic obstructive pulmonary disease (COPD) patients often present considerable individual medical burden in their symptoms, limitations, and well-being that complicate medical treatment. Quality of life (QOL) is an important aspect for measuring the impact of chronic diseases. HRQOL measurement facilitates the evaluation of efficacy of medical interventions and also the detection of groups at risk of psychological or behavioural problems.Methods: COPD patient attending the OPD/IPD are screened as per inclusion and exclusion criteria. After obtaining a written informed consent of eligible patient, they were enrolled in the study. QOL of patient is assessed based on a set of questionnaire i.e. COPD Assessment Test™ (CAT). The questionnaire was translated to Hindi and Marathi. Socio demographic variable like age, sex, education occupation and income are also collected. All 8 questions related to health-improvement and management of COPD. CAT scores were given to each question according to the level of impact.Results: In the total score of CAT we observed that there were 2.04% patients with very good QOL, 25.51% with good QOL, 61.22% with moderate QOL and 11.22% with poor QOL.Conclusions: We conclude that the quality of life is moderate in larger number of patient’s population. The most affected domain was the patient’s energy level. The patients enrolled had COPD from long period of time which might have affected their answer because they have been habitual with the difficulties arising from COPD.


CHEST Journal ◽  
2012 ◽  
Vol 142 (4) ◽  
pp. 728A
Author(s):  
Drosos Tsavlis ◽  
Mamas Theodorou ◽  
Anna Tzoumaka ◽  
Hellie Lithoxopoulou ◽  
Panagiotis Minogiannis ◽  
...  

2020 ◽  
Vol 19 (4) ◽  
pp. 244-250
Author(s):  
Ewelina Dziedzic ◽  
Bożena Zboina ◽  
Krzysztof Cudzik ◽  
Renata Stępień

AbstractIntroduction. Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the world among chronic diseases. The article discusses the relationship between the quality of life of patients with COPD and the presence of diseases associated mainly with hypertension, diabetes and hyperlipidemia. The examination includes subjective and holistic assessment of the patient’s health condition, which allows to notice any disorders and deficits in the functioning of patients with this disease.Aim. The aim of the study was to determine the quality of life of patients with chronic obstructive pulmonary disease depending on the comorbidities.Material and methods. The study included 319 COPD patients treated in the Lung Diseases Clinic with chronic obstructive pulmonary disease. The study was conducted using a diagnostic survey method and analyzing medical records. The research tool assessing patients quality of life was the SGRQ questionnaire (Saint George Hospital Questionaire).Results. Respondents who had a myocardial infarction had a slightly lower quality of life in the “Impact on life subscale” (p=0.047). It was noted that patients with hypertension had a lower quality of life in the domain of “Activity” (p<0.05) and “Impact on life” (p<0.001). However, with hyperlipidemia, a lower quality of life was noticeable in the “Symptoms” (p<0.001) and “Impact on life” subscale (p=0.002).Conclusions. Exacerbation of symptoms in the course of chronic obstructive pulmonary disease, a history of myocardial infarction, hypertension and hyperlipidemia are significantly related to the decreased quality of life of patients. Prevention of these civilization diseases can prevent deterioration of the quality of life of patients.


2020 ◽  
Vol 22 (4) ◽  
pp. 17-22
Author(s):  
N. V. Sharova ◽  
S. L. Grishaev ◽  
D. V. Cherkashin ◽  
S. V. Efimov ◽  
M. A. Kharitonov ◽  
...  

The effectiveness of the early bronchodilatory response of the first dose of a fixed double combination of long-acting bronchodilators of various classes indacaterol/glycopyrronium and long-acting anticholinergics glycopyrronium and Tiotropium in patients suffering from stable chronic obstructive pulmonary disease is compared. It was found that in all patients included in the study and suffering from chronic obstructive pulmonary disease, changes in functional respiratory indicators were accompanied by positive and comparable dynamics of clinical signs: a decrease in the severity of shortness of breath, the impact of the disease on the quality of life and increased tolerance to physical activity. It was found that the combination of indacaterol/glycopyrronium provides rapid, pronounced and prolonged bronchodilation in patients suffering from chronic obstructive pulmonary disease compared to the separate use of glycopyrronium and Tiotropium. Consistent use of glycopyrronium and salbutamol leads to maximum bronchodilation, which makes it advisable to separate the use of prolonged bronchodilators when initiating therapy for chronic obstructive pulmonary disease. Therefore, there is a clinical feasibility of taking not only fixed combinations of bronchodilators of different classes, but also their consistent use. The results of an early bronchodilatory response to the first dose of indacaterol/glycopyrronium can be used as an additional individual predictor of their effectiveness in the treatment of chronic obstructive pulmonary disease.


Respiration ◽  
2016 ◽  
Vol 92 (4) ◽  
pp. 229-234 ◽  
Author(s):  
Alexandru Corlateanu ◽  
Victor Botnaru ◽  
Serghei Covantev ◽  
Silvia Dumitru ◽  
Nikolaos Siafakas

2021 ◽  
Vol 14 (3) ◽  
pp. 63-69
Author(s):  
MARAT F. YAUSHEV ◽  
◽  
ALEXEY P. ALEXEEV ◽  
ILGIZYAR F. MAKHMUTOV ◽  
BORIS M. PETROV ◽  
...  

Pulmonary tuberculosis (TBL), as well as chronic obstructive pulmonary disease (COPD), have a diverse negative impact on the quality of life (QOL) of patients. In this regard, a detailed study of the quality of life of patients with pulmonary tuberculosis in combination with chronic obstructive pulmonary disease retains its importance and relevance.


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