scholarly journals Severe Multiple Sclerosis Relapse After COVID-19 Vaccination: A Case Report

2021 ◽  
Vol 12 ◽  
Author(s):  
Giorgia T. Maniscalco ◽  
Valentino Manzo ◽  
Maria E. Di Battista ◽  
Simona Salvatore ◽  
Ornella Moreggia ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Report ◽  
Risk Ratio ◽  
Neurological Examination ◽  
Vulnerable Population ◽  
Neurological Symptoms ◽  
Multiple Sclerosis Relapse ◽  
Acute Relapse ◽  
Clinical Conditions

We describe a case of acute relapse in a woman with Multiple Sclerosis (MS) shortly after the mRNA COVID-19 vaccination. The patient received a diagnosis of MS in November 2016 at the MS Centre of the A. Cardarelli Hospital (South of Italy). Since that moment, her clinical conditions and pharmacological therapies have been managed at this MS centre where, according to national recommendations, in April 2021, the patient received the BNT162b2 vaccine. Almost 48 h after receiving the vaccine, the patient developed paraesthesia and weakness in her left arm and limbs. The neurological examination revealed walking difficulties while the MRI showed three new voluminous enhancing lesions. After having received methylprednisolone iv for 5 days, the patient's neurological symptoms fully recovered. Along with the implementation of COVID-19 vaccination programmes among vulnerable population, further studies are needed in order to improve our knowledge on the benefit/risk ratio of COVID-19 vaccines.

scholarly journals COVID-19 in teriflunomide-treated patients with multiple sclerosis: a case report and literature review.

2021 ◽  
pp. 102734
Author(s):  
Fioravante Capone ◽  
Francesco Motolese ◽  
Tiziano Luce ◽  
Mariagrazia Rossi ◽  
Alessandro Magliozzi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Report ◽  
Literature Review

scholarly journals Neuropathic pain post-COVID-19: a case report

2021 ◽  
Vol 14 (7) ◽  
pp. e243459
Author(s):  
Matthew McWilliam ◽  
Michael Samuel ◽  
Fadi Hasan Alkufri
Keyword(s):  
Neuropathic Pain ◽  
Case Report ◽  
Hospital Admission ◽  
Skin Biopsy ◽  
Neurological Examination ◽  
Autonomic Failure ◽  
Whole Body ◽  
Shortness Of Breath ◽  
Burning Pain ◽  
Electrophysiological Tests

A 61-year-old man with no significant medical history developed fever, headache and mild shortness of breath. He tested positive for SARS-CoV-2 and self-isolated at home, not requiring hospital admission. One week after testing positive, he developed acute severe burning pain affecting his whole body, subsequently localised distally in the limbs. There was no ataxia or autonomic failure. Neurological examination was unremarkable. Electrophysiological tests were unremarkable. Skin biopsy, lumbar puncture, enhanced MRI of the brachial plexus and MRI of the neuroaxis were normal. His pain was inadequately controlled with pregabalin but improved while on a weaning regimen of steroids. This case highlights the variety of possible symptoms associated with SARS-CoV-2 infection.

Sign in / Sign up

Export Citation Format

Share Document