scholarly journals SARS-CoV-2 infection after alemtuzumab in a multiple sclerosis patient: milder disease symptoms in comparison with coinfected relatives: a case report and review of the literature

Author(s):  
Lorenzo Saraceno ◽  
Emanuela Laura Susani ◽  
Maria Raffaella Marazzi ◽  
Maria Cristina Moioli ◽  
Elio Clemente Agostoni ◽  
...  
2021 ◽  
pp. 089719002110632
Author(s):  
Claire V Klimko ◽  
James M Sanders ◽  
Meagan L Johns

Purpose: The purpose of this case report is to describe spasticity and encephalopathy that developed in a multiple sclerosis patient following carbapenem administration. Summary: A 55-year-old female with multiple sclerosis developed spasticity and encephalopathy within 24 hours of meropenem and ertapenem administration. This was the second time that she had developed encephalopathy following carbapenem administration. The patient gradually recovered over four days following discontinuation of carbapenem therapy. Conclusion: Carbapenem neurotoxicity, a well-documented adverse effect, has been linked to several risk factors, including central nervous system lesions. Despite this, there is little evidence describing the risk of neurotoxicity in patients with multiple sclerosis. It is important to understand the potential adverse effects of carbapenems in specific patient populations to help guide appropriate treatment of infections.


2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Vimal V Jhaveri ◽  
Mary T Lasalvia

Abstract Ureaplasma species are small, fastidious bacteria that frequently colonize the lower reproductive tract of asymptomatic hosts. These organisms have been well described to cause chorioamnionitis, neonatal infection, and urethritis, and to a lesser degree surgical site infection and infection in transplant recipients. Outside of these settings, invasive Ureaplasma infections are rare. We describe the case of a young woman receiving rituximab for multiple sclerosis who presented with fever and bilateral renal abscesses due to Ureaplasma spp., which was successfully treated with oral doxycycline. We searched the literature for cases of invasive Ureaplasma infection and found a patient population that predominates with humoral immunodeficiency, either congenital or iatrogenic. Diagnostic and therapeutic interventions are discussed.


PM&R ◽  
2014 ◽  
Vol 6 (9) ◽  
pp. S312
Author(s):  
Brian Altman ◽  
Maria Margarita Lopez ◽  
Sanjeev Agarwal

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