scholarly journals Contagious Yawning and Seasonal Climate Variation

Author(s):  
Andrew C. Gallup ◽  
Omar Tonsi Eldakar
BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e024197 ◽  
Author(s):  
Qin Zhang ◽  
Yuliang Chen ◽  
Yu Fu ◽  
Tao Liu ◽  
Qingying Zhang ◽  
...  

ObjectiveDengue is a mosquito-transmitted virus infection that remains rampant across the tropical and subtropical areas worldwide. However, the spatial and temporal dynamics of dengue transmission are poorly understood in Chao-Shan area, one of the most densely populated regions on China’s southeastern coast, limiting disease control efforts. We aimed to characterise the epidemiology of dengue and assessed the effect of seasonal climate variation on its dynamics in the area.DesignA spatio-temporal descriptive analysis was performed in three cities including Shantou, Chaozhou and Jieyang in Chao-Shan area during the period of 2014–2017.SettingData of dengue cases of three cities including Shantou, Chaozhou and Jieyang in Chao-Shan area during 2014–2017 were extracted. Data for climatic variables including mean temperature, relative humidity and rainfall were also compiled.MethodologyThe epidemiology and dynamics of dengue were initially depicted, and then the temporal dynamics related to climatic drivers was assessed by a wavelet analysis method. Furthermore, a generalised additive model for location, scale and shape model was performed to study the relationship between seasonal dynamics of dengue and climatic drivers.ResultsAmong the cities, the number of notified dengue cases in Chaozhou was greatest, accounting for 78.3%. The median age for the notified cases was 43 years (IQR: 27.0–58.0 years). Two main regions located in Xixin and Chengxi streets of Chaozhou with a high risk of infection were observed, indicating that there was substantial spatial heterogeneity in intensity. We found an annual peak incidence occurred in autumn across the region, most markedly in 2015. This study reveals that periods of elevated temperatures can drive the occurrence of dengue epidemics across the region, and the risk of transmission is highest when the temperature is between 25°C and 28°C.ConclusionOur study contributes to a better understanding of dengue dynamics in Chao-Shan area.


Plants ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 59 ◽  
Author(s):  
Janardan Khadka ◽  
Narendra Yadav ◽  
Gila Granot ◽  
Gideon Grafi

Plants thriving in desert environments are suitable for studying mechanisms for plant survival under extreme seasonal climate variation. We studied epigenetic mechanisms underlying seasonal growth cycles in the desert plant Zygophyllum dumosum Boiss., which was previously shown to be deficient in repressive markers of di-methyl and tri-methyl H3K9 and their association with factors regulating basic cell functions. We showed a contingent association between rainfall and seasonal growth and the epigenetic marker of dimethyl H3K4, which disappears upon entry into the dry season and the acquisition of a dormant state. DNA methylation is not affected by a lack of H3K9 di-methyl and tri-methyl. Changes in methylation can occur between the wet and dry season. Proteome analysis of acid soluble fractions revealed an extensive reduction in ribosomal proteins and in proteins involved in chloroplasts and mitochondrial activities during the dry seasons concomitantly with up-regulation of molecular chaperone HSPs. Our results highlight mechanisms underlying Z. dumosum adaptation to seasonal climate variation. Particularly, summer dormancy is associated with a loss of the permissive epigenetic marker dimethyl H3K4, which might facilitate genome compaction concomitantly with a significant reduction in proteins involved in basic cell functions. HSP chaperones might safeguard the integrity of cell components.


2016 ◽  
Vol 6 (16) ◽  
pp. 5614-5622 ◽  
Author(s):  
F. Stephen Dobson ◽  
Jeffrey E. Lane ◽  
Matthew Low ◽  
Jan O. Murie

Author(s):  
Janardan Khadka ◽  
Narendra Singh Yadav ◽  
Gila Granot ◽  
Gideon Grafi

Plants thriving in desert environments are suitable for studying mechanisms for plant survival under extreme seasonal climate variation. Zygophyllum dumosum Boiss, like many other Zygophyllaceae species, displays a unique epigenetic mechanism whereby the repressive markers di- and tri-methyl of H3K9 do not exist. We studied epigenetic mechanisms underlying seasonal growth cycles in Z. dumosum and their association with factors regulating basic cell functions. We showed strong association between rainfall and seasonal growth and the epigenetic marker of dimethyl H3K4, which disappears on entry into the dry season and the acquisition of dormant state. DNA methylation is not affected by lack of H3K9 di and tri methyl and changes in methylation pattern are apparent on entry into the dry season. Proteome analysis of acid soluble fractions revealed extensive reduction in ribosomal proteins and in proteins involved in chloroplasts and mitochondria activities during the dry seasons concomitantly with up-regulation of molecular chaperone HSPs. Our results highlight mechanisms underlying Z. dumosum adaptation to seasonal climate variation. Particularly, summer dormancy is associated with loss of the permissive epigenetic marker dimethyl H3K4, which might facilitate genome compaction, concomitantly with significant reduction in proteins involved in basic cell functions (i.e., protein synthesis, photosynthesis and respiration).


2013 ◽  
Vol 18 (2) ◽  
Author(s):  
Craig Nicolson ◽  
Matthew Berman ◽  
Colin Thor West ◽  
Gary P. Kofinas ◽  
Brad Griffith ◽  
...  

Eos ◽  
2016 ◽  
Vol 97 ◽  
Author(s):  
Takeshi Doi

Tropical Precipitation System Workshop 2015; Yokohama, Japan, 3–4 September 2015


2013 ◽  
Vol 16 (6) ◽  
pp. 336
Author(s):  
Marko Boban ◽  
Viktor Persic ◽  
Zeljko Jovanovic ◽  
Niksa Drinkovic ◽  
Milan Milosevic ◽  
...  

<p><b>Background:</b> Current knowledge on the pervasiveness of increased nutritional risk in cardiovascular diseases is limited. Our aim was to analyze the characteristics of nutritional risk screening in patients scheduled for rehabilitation after heart surgery. Prevalence and extent of nutritional risk were studied in connection with patients' characteristics and seasonal climate effects on weight loss dynamics.</p><p><b>Methods:</b> The cohort included 65 consecutive patients with an age range of 25-84 years, 2-6 months after surgical treatment for ischemic or valvular heart disease. Nutritional risk screening was appraised using a standardized NRS-2002 questionnaire. Groups were analyzed according to a timeline of rehabilitation according to the "cold" and "warm" seasons of the moderate Mediterranean climate in Opatija, Croatia.</p><p><b>Results:</b> Increased nutritional risk scores (NRS-2002) of >3 were found in 96% of studied patients. Mean NRS-2002 of patients was 5.0 � 1.0, with a percentage weight loss history of 11.7% � 2.2% (4.6-19.0). Risk was found to be more pronounced during the warmer season, with NRS-2002 scores of 5.3 � 0.7 versus 4.8 � 1.1 (<i>P</i> = 0.136) and greater loss of weight of 13.0% � 3.2% versus 10.6% � 3% (<i>P</i> = 0.005), respectively. Increased nutritional risk correlated significantly with creatinine concentrations (rho = 0.359; <i>P</i> = 0.034 versus 0.584; <i>P</i> = 0.001, respectively). Significant discordance in correlations was found between NRS-2002 and the decrease in left ventricle systolic function (rho correlation coefficient [rho-cc] = -0.428; <i>P</i> = 0.009), the increase in glucose concentrations (cc = 0.600; <i>P</i> < 0.001), and the decrease in erythrocyte counts (cc = -0.520; <i>P</i> = 0.001) during the colder season.</p><p><b>Conclusion:</b> Increased nutritional risk was found to be frequently expressed in the course of rehabilitation after heart surgery. Although seasonal climate effects influenced the weight loss dynamics, the impact on reproducibility of NRS-2002 was clinically less important. Further studies on the connection of nutritional risk with composited end points might offer improvements in overall quality of treatment.</p>


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