scholarly journals White Matter Abnormalities in Patients With Typhoon-Related Posttraumatic Stress Disorder

2021 ◽  
Vol 15 ◽  
Author(s):  
Hui Juan Chen ◽  
Rongfeng Qi ◽  
Jun Ke ◽  
Jie Qiu ◽  
Qiang Xu ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
White Matter ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Clinical Symptoms ◽  
Diffusion Tensor ◽  
Traumatic Event ◽  
Mean Diffusivity ◽  
Cerebral White Matter ◽  
White Matter Abnormalities

Patients with posttraumatic stress disorder (PTSD) might have white matter abnormalities. However, less is known about white matter changes after exposing a specific traumatic event. The purpose of this study was to explore the abnormalities of diffusion in cerebral white matter and its relationship with the clinical symptoms in patients with PTSD by using diffusion tensor imaging (DTI). Diffusion-weighted imaging of the cerebrum was performed in typhoon survivors with (n = 27) and without PTSD (n = 33) and healthy controls (HCs) (n = 30). Differences in fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were calculated among groups using voxel-based analysis of the DTI data. Correlations between diffusion indices and clinical symptoms in patients with PTSD were also assessed. Both patients with PTSD and trauma-exposed control (TEC) group showed increased FA in the anterior limb of the internal capsule, forceps of the corpus callosum, and corona radiata relative to the HC group. Additionally, there was a negative correlation between FA values in the white matter and the clinical symptoms. Trauma exposure may result in disruption of cerebral white matter in individuals with or without PTSD, particularly in the frontal fibers. Aberrant white matter alterations may be associated with the severity of PTSD symptoms.

Posttraumatic stress disorder, symptoms, and white matter abnormalities among combat-exposed veterans

2017 ◽  
Vol 12 (4) ◽  
pp. 989-999 ◽  
Author(s):  
Kirstin Aschbacher ◽  
Synthia H. Mellon ◽  
Owen M. Wolkowitz ◽  
Clare Henn-Haase ◽  
Rachel Yehuda ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
White Matter ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
White Matter Abnormalities ◽  
Posttraumatic Stress Disorder Symptoms

White matter abnormalities in Gulf War veterans with posttraumatic stress disorder: A pilot study

2015 ◽  
Vol 51 ◽  
pp. 567-576 ◽  
Author(s):  
Linda M. Bierer ◽  
Iliyan Ivanov ◽  
David M. Carpenter ◽  
Edmund W. Wong ◽  
Julia A. Golier ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
White Matter ◽  
Pilot Study ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Gulf War ◽  
War Veterans ◽  
White Matter Abnormalities ◽  
Gulf War Veterans

Decreased Gray-To-White Matter Contrast Within the Ventromedial Prefrontal Cortex of Individuals With Posttraumatic Stress Disorder

2021 ◽  
Vol 89 (9) ◽  
pp. S231-S232
Author(s):  
Nathaniel Harnett ◽  
Sanne van Rooij ◽  
Timothy Ely ◽  
Jennifer Stevens ◽  
Antonia Seligowski ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Prefrontal Cortex ◽  
White Matter ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Ventromedial Prefrontal Cortex

Consequences Assessment of Destructive Informational Effects on the Basis of Complex Analysis of Biomarker System and its Overcoming

2021 ◽  
Vol 4 (5) ◽  
Author(s):  
Yuriy Danyk
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Effective Treatment ◽  
Posttraumatic Stress ◽  
Biological Markers ◽  
Complex Analysis ◽  
Stress Disorder ◽  
Clinical Symptoms ◽  
Negative Effects ◽  
Diagnostic Threshold ◽  
Crisis Situations

The article is based on the concept of forming various stress-related disorders in crisis situations. It is proved that destructive informational effects in modern conditions are an integral part in the formation of crisis situation syndromes and posttraumatic stress disorder. In the course of research, the possibility of using the system of biological markers for timely detection and effective treatment of stress-associated and informational disorders was established (before other clinical symptoms or their reaching diagnostic threshold). It also allows timely assessment of the subjective adaptation threshold of people at risk, to identify and reduce the negative effects of stress-related disorders. The use of the biomarkers was also researched for the diagnosis, treatment, rehabilitation, prevention of stress-related disorders among participants of crisis situations.

scholarly journals White matter abnormalities in the corpus callosum with cognitive impairment in Parkinson disease

Neurology ◽  
2018 ◽  
Vol 91 (24) ◽  
pp. e2244-e2255 ◽  
Author(s):  
Ian O. Bledsoe ◽  
Glenn T. Stebbins ◽  
Doug Merkitch ◽  
Jennifer G. Goldman
Keyword(s):  
Cognitive Impairment ◽  
White Matter ◽  
Corpus Callosum ◽  
Parkinson Disease ◽  
Information Transfer ◽  
Diffusion Tensor ◽  
Anterior Segment ◽  
Mean Diffusivity ◽  
Cognitive Domain ◽  
White Matter Abnormalities

ObjectiveTo evaluate microstructural characteristics of the corpus callosum using diffusion tensor imaging (DTI) and their relationships to cognitive impairment in Parkinson disease (PD).MethodsSeventy-five participants with PD and 24 healthy control (HC) participants underwent structural MRI brain scans including DTI sequences and clinical and neuropsychological evaluations. Using Movement Disorder Society criteria, PD participants were classified as having normal cognition (PD-NC, n = 23), mild cognitive impairment (PD-MCI, n = 35), or dementia (PDD, n = 17). Cognitive domain (attention/working memory, executive function, language, memory, visuospatial function) z scores were calculated. DTI scalar values, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD), were established for 5 callosal segments on a midsagittal plane, single slice using a topographically derived parcellation method. Scalar values were compared among participant groups. Regression analyses were performed on cognitive domain z scores and DTI metrics.ResultsParticipants with PD showed increased AD values in the anterior 3 callosal segments compared to healthy controls. Participants with PDD had significantly increased AD, MD, and RD in the anterior 2 segments compared to participants with PD-NC and most anterior segment compared to participants with PD-MCI. FA values did not differ significantly between participants with PD and participants with HC or among PD cognitive groups. The strongest associations for the DTI metrics and cognitive performance occurred in the most anterior and most posterior callosal segments, and also reflected fronto-striatal and posterior cortical type cognitive deficits, respectively.ConclusionsMicrostructural white matter abnormalities of the corpus callosum, as measured by DTI, may contribute to PD cognitive impairment by disrupting information transfer across interhemispheric and callosal–cortical projections.

The exposure to traumatic events and symptoms of posttraumatic stress disorder among Korean journalists

Journalism ◽  
2017 ◽  
Vol 19 (9-10) ◽  
pp. 1308-1325 ◽  
Author(s):  
Mina Lee ◽  
Eun Hye Ha ◽  
Jung Kun Pae
Keyword(s):  
Social Support ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Coping Strategy ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Traumatic Events ◽  
Ptsd Symptoms ◽  
Negative Beliefs ◽  
Traumatic Event Exposure

This study investigated posttraumatic stress disorder (PTSD) symptoms on Korean journalists and the contributing variables. Predicting variables included the exposure to traumatic events, coping strategy, social support, optimism, negative beliefs, and the journalists’ occupational perspectives. A total of 367 Korean journalists participated in the survey. The findings revealed that, first, Korean journalists had suffered severely from PTSD symptoms according to the prevalence rate. Second, the extent of traumatic event exposure, the length of career, the use of dysfunctional coping strategy, a lack of social support, and negative beliefs were identified as significantly related variables. Finally, occupational perspectives showed meaningful associations with development of the symptoms. This study provided an empirical analysis of Korean journalists’ experiences of traumatic events and psychological stress for the first time.

Dismissive Attachment and Posttraumatic Stress Disorder among Securely and Insecurely Attached Belgian Security Workers

2009 ◽  
Vol 105 (3) ◽  
pp. 889-899 ◽  
Author(s):  
Stefan Bogaerts ◽  
Maarten J. J. Kunst ◽  
Frans W. Winkel
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Attachment Style ◽  
Attachment Styles ◽  
Stress Disorder ◽  
Ptsd Symptom ◽  
Traumatic Event ◽  
Insecure Attachment ◽  
Grandiose Narcissism ◽  
Preoccupied Attachment

This study examined Posttraumatic Stress Disorder in relation to secure and insecure attachment styles based on data collected in a sample of 81 Belgian security workers. All had experienced one traumatic event in the previous year. The sample was divided into a securely attached and an insecurely attached group. The three PTSD symptom scales, Re-experiencing, Avoidance, and Hyperarousal, differentiated significantly between the two attachment groups; the dismissive attachment style was negatively related to PTSD. Individuals with a positive view of themselves and a negative view of others have less risk of developing PTSD than those with a fearful or preoccupied attachment style. A relationship between the dismissive attachment style with grandiose narcissism seems possible. Interest has been expressed in medical approaches; therefore, the importance of medical research on PTSD is emphasized.

Three Studies on the Reliability and Validity of a Self-Report Measure of Posttraumatic Stress Disorder

Assessment ◽  
1996 ◽  
Vol 3 (1) ◽  
pp. 17-25 ◽  
Author(s):  
Dean Lauterbach ◽  
Scott Vrana
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Discriminant Validity ◽  
Stress Disorder ◽  
Traumatic Event ◽  
Clinical Sample ◽  
Reliability And Validity ◽  
Self Report ◽  
Highly Correlated ◽  
The Impact

This paper describes three studies of the reliability and validity of a newly revised version of the Purdue Posttraumatic Stress Disorder scale (PPTSD-R). The PPTSD-R is a 17-item questionnaire that yields four scores: Reexperiencing, Avoidance, Arousal, and Total. It is highly internally consistent (α = .91), and the scores are relatively stable across time. The PPTSD-R is highly correlated with other measures of PTSD symptomatology and moderately correlated with measures of related psychopathology, providing preliminary support for the measure's convergent and discriminant validity. It reliably distinguishes between groups of people who were and were not traumatized, it is sensitive to the impact of different types of traumatic events, and (within a clinical sample) it discriminates between those who did and did not seek treatment for difficulty coping with the traumatic event being assessed. The PPTSD-R shows promise as a measure of PTSD symptoms in the college population.

Posttraumatic Stress Disorder

2020 ◽  
pp. 95-104
Author(s):  
Joel Paris
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Event

Posttraumatic stress disorder (PTSD) differs from other categories that are underdoing diagnostic epidemics, in that its treatment is primarily based on psychotherapy. PTSD tends to be overdiagnosed when clinicians attribute, rightly or wrongly, symptoms to a traumatic event. Yet most people who undergo trauma do not develop PTSD, and people without trauma can have similar symptoms. This chapter shows how the construct of PTSD arose historically. A problematic DSM definition, in relation both to the nature of stressors and the links between stress and outcome, causes PTSD to be overdiagnosed. The result is that many patients are receiving the wrong kind of psychotherapy for their problems.

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