scholarly journals Velocity and Pulsatility Measures in the Perforating Arteries of the Basal Ganglia at 3T MRI in Reference to 7T MRI

2021 ◽  
Vol 15 ◽  
Author(s):  
Tine Arts ◽  
Timion A. Meijs ◽  
Heynric Grotenhuis ◽  
Michiel Voskuil ◽  
Jeroen Siero ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Flow Velocity ◽  
Signal To Noise Ratio ◽  
Statistical Significance ◽  
7 Tesla ◽  
3T Mri ◽  
Perforating Artery ◽  
Artery Flow ◽  
Mri Measurements ◽  
Perforating Arteries

Cerebral perforating artery flow velocity and pulsatility can be measured using 7 tesla (T) MRI. Enabling these flow metrics on more widely available 3T systems would make them more employable. It is currently unknown whether these measurements can be performed at 3T MRI due to the lower signal-to-noise ratio (SNR). Therefore, the aim of this study is to investigate if flow velocity and pulsatility in the perforating arteries of the basal ganglia (BG) can be measured at 3T MRI and assess the agreement with 7T MRI measurements as reference. Twenty-nine subjects were included, of which 14 patients with aortic coarctation [median age 29 years (21–72)] and 15 controls [median age 27 years (22–64)]. Using a cardiac-gated 2D phase-contrast MRI sequence BG perforating arteries were imaged at 3T and 7T MRI and perforating artery density (Ndensity, #/cm2), flow velocity (Vmean, cm/s) and pulsatility index (PI) were determined. Agreement between scanner modalities was assessed using correlation and difference plots with linear regression. A p-value ≤ 0.05 indicated statistical significance. It was shown that perforating artery flow velocity and pulsatility can be measured at 3T MRI (Ndensity = 0.21 ± 0.11; Vmean = 6.04 ± 1.27; PI = 0.49 ± 0.19), although values differed from 7T MRI measurements (Ndensity = 0.95 ± 0.21; Vmean = 3.89 ± 0.56; PI = 0.28 ± 0.08). The number of detected arteries was lower at 3T (5 ± 3) than 7T MRI (24 ± 6), indicating that 3T MRI is on average a factor 4.8 less sensitive to detect cerebral perforating arteries. Comparison with 7T MRI as reference showed some agreement in Ndensity, but little to no agreement for Vmean and PI. Equalizing the modalities’ sensitivity by comparing the detected arteries on 7T MRI with the highest velocity with all vessels detected on 3T MRI, showed some improvement in agreement for PI, but not for Vmean. This study shows that it is possible to measure cerebral perforating artery flow velocity and pulsatility at 3T MRI, although an approximately fivefold sample size is needed at 3T relative to 7T MRI for a given effect size, and the measurements should be performed with equal scanner field strength and protocol.

Abstract W P45: High Resolution Images of Perforating Arteries With 7T MRA in Acute Subcortical Infarction

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Hideki Ohba ◽  
Taisuke Harada ◽  
Makoto Sasaki ◽  
Kazumasa Ohura ◽  
Tatsunori Natori ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Infarct Volume ◽  
7 Tesla ◽  
Ischemic Lesion ◽  
Clinical Prognosis ◽  
Tof Mra ◽  
Perforating Artery ◽  
Subcortical Infarction ◽  
Perforating Arteries

Introduction: Patients with acute subcortical infarction show various clinical courses according to the pathology of perforating artery so that the noninvasive and precise neuroradiological evaluation of these arteries is very important for prevention of progression and recurrence of the disease. 7 Tesla (7T) - MRI (Magnetic Resonance Imaging) makes it possible to visualize perforating arteries in a way that would not otherwise be possible using conventional MRI. We attempted to assess perforating arteries and infarct lesions in the lenticulostriate artery (LSA) area using 7T- High resolution MRA (Magnetic Resonance Angiography), and to evaluate the association between image findings and clinical courses of treatment. Method: We included 13 patients (M:F = 7:6, mean age: 65 years old) with acute noncardioembolic stroke in LSA area detected by 1.5-T MRI. 7T MRI was acquired among these patients within 2 weeks after onset to visualize responsible LSA and to measure the volume of infarction by 7T-MRI- 3D-TOF MRA, 3D-FLAIR. We also evaluated the association between these results and the severity of stroke by National Institute of Health Stroke Scale (NIHSS). Results: Perforating arteries in the basal ganglia area were clearly visualized in all patients using 7T MRA. According to the location of occlusion and ischemic lesion, patients were categorized into 3 groups (A, B, and C): Group A - patients with proximal branch occlusion of LSA (2 cases), Group B - patients with occlusion of LSA adjacent to the ischemic lesion (7 cases), Group C - no occlusions (4 cases) in LSA associated with infarction. Significant association between overall infarct volume and NIHSS(r=0.636, p=0.020)was observed, whereas infarct volume of each group was not associated with NIHSS. Clinical outcome were not associated with volume of infarction in all cases(p=0.12). However, there were no patients whose symptoms progressed in Group C. Conclusion: 7 T-MRA can provide a clear visualization of perforating arteries and occluded lesions. It can be a useful and noninvasive diagnostic tool to study clinical prognosis after treatment in acute subcortical infarction.

scholarly journals Perforator preservation technologies (PPT) based on a new neuro-interventional classification in endovascular treatment of perforator involving aneurysms (piANs)

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Chen Li ◽  
Ao-Fei Liu ◽  
Han-Cheng Qiu ◽  
Xianli Lv ◽  
Ji Zhou ◽  
...  
Keyword(s):  
Endovascular Therapy ◽  
Saccular Aneurysm ◽  
Type I ◽  
Type Ii ◽  
Fusiform Aneurysm ◽  
Type Iii ◽  
Perforating Artery ◽  
Protection Technology ◽  
Perforating Arteries

Abstract Background Treatment of perforator involving aneurysm (piAN) remains a challenge to open and endovascular neurosurgeons. Our aim is to demonstrate a primary outcome of endovascular therapy for piANs with the use of perforator preservation technologies (PPT) based on a new neuro-interventional classification. Methods The piANs were classified into type I: aneurysm really arises from perforating artery, type II: saccular aneurysm involves perforating arteries arising from its neck (IIa) or dome (IIb), and type III: fusiform aneurysm involves perforating artery. Stent protection technology of PPT was applied in type I and III aneurysms, and coil-basket protection technology in type II aneurysms. An immediate outcome of aneurysmal obliteration after treatment was evaluated (satisfactory obliteration: the saccular aneurysm body is densely embolized (I), leaving a gap in the neck (IIa) or dome (IIb) where the perforating artery arising; fusiform aneurysm is repaired and has a smooth inner wall), and successful perforating artery preservation was defined as keeping the good antegrade flow of those perforators on postoperative angiography. The periprocedural complication was closely monitored, and clinical and angiographic follow-ups were performed. Results Six consecutive piANs (2 ruptured and 4 unruptured; 1 type I, 2 type IIa, 2 type IIb, and 1 type III) in 6 patients (aged from 43 to 66 years; 3 males) underwent endovascular therapy between November 2017 and July 2019. The immediate angiography after treatment showed 6 aneurysms obtained satisfactory obliteration, and all of their perforating arteries were successfully preserved. During clinical follow-up of 13–50 months, no ischemic or hemorrhagic event of the brain occurred in the 6 patients, but has one who developed ischemic event in the territory of involving perforators 4 h after operation and completely resolved within 24 h. Follow-up angiography at 3 to 10M showed patency of the parent artery and perforating arteries of treated aneurysms, with no aneurysmal recurrence. Conclusions Our perforator preservation technologies on the basis of the new neuro-interventional classification seem feasible, safe, and effective in protecting involved perforators while occluding aneurysm.

Effect of Ketanserin on Global Cerebral Blood Flow and Middle Cerebral Artery Flow Velocity

1995 ◽  
Vol 80 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Andreas Weyland ◽  
Heidrun Stephan ◽  
Frank Grune ◽  
Wolfgang Weyland ◽  
Hans Sonntag
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Middle Cerebral Artery ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Global Cerebral Blood Flow ◽  
Artery Flow

scholarly journals Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity.

Circulation ◽  
1992 ◽  
Vol 85 (5) ◽  
pp. 1899-1911 ◽  
Author(s):  
J W Doucette ◽  
P D Corl ◽  
H M Payne ◽  
A E Flynn ◽  
M Goto ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Flow Velocity ◽  
Guide Wire ◽  
Coronary Artery Flow ◽  
Artery Flow

scholarly journals Fetal internal carotid artery flow velocity time waveforms in twin pregnancies

1988 ◽  
Vol 16 (5-6) ◽  
pp. 405-409 ◽  
Author(s):  
Shimon Degani ◽  
Joav Paltiely ◽  
Reuven Lewinsky ◽  
Israel Shapiro ◽  
Mordechai Sharf
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Flow Velocity ◽  
Internal Carotid ◽  
Artery Flow ◽  
Twin Pregnancies

Safe Stereotactic Biopsy for Basal Ganglia Lesions: Avoiding Injury to the Basal Perforating Arteries

2018 ◽  
Vol 96 (4) ◽  
pp. 244-248 ◽  
Author(s):  
Sumito Sato ◽  
Mitsuru Dan ◽  
Hirofumi Hata ◽  
Kazuhiro Miyasaka ◽  
Mitsuto Hanihara ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Stereotactic Biopsy ◽  
Perforating Arteries

scholarly journals Relation between Fetal Renal Artery Doppler ‎Indices and Non-PROM Oligohydramnios in ‎Third Trimester of Pregnancy

2021 ◽  
pp. 1-8
Author(s):  
Asmaa Ibrahim Laag ◽  
Nareman Mahmoud Elhamamy ◽  
Amr‏ ‏Mohamed Tawfek Elbadry ◽  
Atef Hammad Teama
Keyword(s):  
Amniotic Fluid ◽  
Renal Artery ◽  
Flow Velocity ◽  
Pulsatility Index ◽  
Resistance Index ◽  
Normal Amount ◽  
Amniotic Fluid Index ◽  
Group I ◽  
Significant Difference ◽  
Artery Flow

Background: Amniotic fluid is the liquid which surround the fetus after the first few weeks of gestation. Amniotic fluid is derived mostly from the fetus and has many functions that are essential for normal growth and development. The aim of this work is to study the relation between fetal renal artery flow velocity waveforms and amniotic fluid volume in normal pregnancies and those complicated by oligohydramnios. Methods: This prospective observational study was carried out on 40pregnant women (10) of them were with normal amount of amniotic fluid (group I), while (30) of them suffered from oligohydramnios (group II).By using color doppler ultrasound imaging, the fetal renal circulation can be assessed. Intermittent assessment of renal artery flow velocity waveforms during the early stages of pregnancy may help in predicting changes in amniotic fluid dynamics. Results: There was a non-significant difference between cases with normal amount of amniotic fluid and cases with oligohydramnios in Gestational age, Maternal age, fetal femur length, bi parietal diameter, abdominal circumference and Fetal weight. There were increased values of fetal renal artery Resistance index (RI) and Pulsatility index (PI) in cases of oligohydramnios than cases with normal amount of amniotic fluid. There was no correlation between Peak systolic velocity (PSV) and Amniotic fluid index (AFI). There was a significant difference in End diastolic velocity (EDV) between cases with normal amount of amniotic fluid and cases with oligohydramnios. Also, there was a significant difference in Systolic diastolic ratio (S/D) and Amniotic fluid index (AFI) between cases with normal amount of amniotic fluid and cases with oligohydramnios. Conclusions: There is a relation between renal artery flow velocity waveforms and oligohydramnios using Pulsed wave Doppler Ultrasonography. There are higher values of renal artery Resistance index and Pulsatility index in cases of oligohydramnios more than cases with normal amount of amniotic fluid.

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