Relation between Fetal Renal Artery Doppler ‎Indices and Non-PROM Oligohydramnios in ‎Third Trimester of Pregnancy

Background: Amniotic fluid is the liquid which surround the fetus after the first few weeks of gestation. Amniotic fluid is derived mostly from the fetus and has many functions that are essential for normal growth and development. The aim of this work is to study the relation between fetal renal artery flow velocity waveforms and amniotic fluid volume in normal pregnancies and those complicated by oligohydramnios. Methods: This prospective observational study was carried out on 40pregnant women (10) of them were with normal amount of amniotic fluid (group I), while (30) of them suffered from oligohydramnios (group II).By using color doppler ultrasound imaging, the fetal renal circulation can be assessed. Intermittent assessment of renal artery flow velocity waveforms during the early stages of pregnancy may help in predicting changes in amniotic fluid dynamics. Results: There was a non-significant difference between cases with normal amount of amniotic fluid and cases with oligohydramnios in Gestational age, Maternal age, fetal femur length, bi parietal diameter, abdominal circumference and Fetal weight. There were increased values of fetal renal artery Resistance index (RI) and Pulsatility index (PI) in cases of oligohydramnios than cases with normal amount of amniotic fluid. There was no correlation between Peak systolic velocity (PSV) and Amniotic fluid index (AFI). There was a significant difference in End diastolic velocity (EDV) between cases with normal amount of amniotic fluid and cases with oligohydramnios. Also, there was a significant difference in Systolic diastolic ratio (S/D) and Amniotic fluid index (AFI) between cases with normal amount of amniotic fluid and cases with oligohydramnios. Conclusions: There is a relation between renal artery flow velocity waveforms and oligohydramnios using Pulsed wave Doppler Ultrasonography. There are higher values of renal artery Resistance index and Pulsatility index in cases of oligohydramnios more than cases with normal amount of amniotic fluid.

Treating of Joint Pain - Arthritis through YOGA

Arthritis is the swelling and tenderness of one or more of your joints. The main symptoms of arthritis are joint pain and stiffness, which typically worsen with age. Although there's no cure for arthritis, treatments have improved greatly in recent years and, for many types of arthritis, particularly inflammatory arthritis, there's a clear benefit in starting treatment at an early stage. Cartilage is a firm but flexible connective tissue in your joints. It protects the joints by absorbing the pressure and shock created when you move and put stress on them. A reduction in the normal amount of this cartilage tissue cause some forms of arthritis. Yoga is giving new lease of life to many, so to tackle chronic diseases it is providing remedies which will be effective for your entire life. It is delivered to many people by PATANJALI. Yoga can give support to patients having arthritis through its numerous relevant postures (asana’s) which can be done very simply. Yoga does not send a message that if you do it regularly you will be relieved from a particular ailment. If it is performed each day it will add vital energy for smooth life even if you are suffering from any long term ailment. In this article we will be providing 5 postures (asana’s) which can be performed at any time in the day but early morning will always be preferred (empty stomach) to get good result. Secondly this postures must be implemented after due consultation with your physician. If your physician disapproves don’t do these postures as it will be harmful for your body.

The Effectiveness of Low-investment Pachinko/pachislot in Reducing Gambling-related Harms: A Cross Sectional Study

Background: Pachinko and pachislot are popular types of gambling activities in Japan. Prior studies in Japan have reported a concerning prevalence of gambling disorder among university students and adult players. While these studies have identified various gambling-related harms, Japanese research on harm-minimization strategies is scarce. Therefore, the present study aimed to analyze the effectiveness of low-investment pachinko and pachislot as a harm-reduction strategy. Methods: We also called gamblers who played for the normal amount as “normal-pachi players,” those who played pachinko and pachislot for half of the normal amount were called “half-pachi players,” and those who played for a quarter of the normal amount were called “quarter-pachi players.” To assess the effect of harm reduction, a one-way ANCOVA was conducted to compare the impact of the groups (normal-pachi players [n= 101], half-pachi players [n= 104], and quarter-pachi players [n= 100]) on dependent variables, namely the number of days players had gambled during the prior month, the total time and amount of money spent on gambling, debts caused by gambling, gambling severity, cognitive distortion, depressive symptoms, and disability. Results: We demonstrated that the amount of money spent by quarter-pachi players on gambling during the past month was lower than that of normal-pachi players. However, we did not find significant differences with respect to any other gambling-related harms among normal-, half-, and quarter-pachi players. Conclusion: Low-investment pachinko and pachislot can reduce the amount of money spent on gambling. It can thus partly act as a harm-minimization strategy. Moreover, the results of present study indicate that the level of disability at work affects various outcomes for gamblers. Given that 90% of the participants in this study were employed, the results of this study may have important implications for employed gamblers. Interventions should be devised to reduce work-related disabilities among employed adults with a gambling disorder.

Periodic Severe Angioedema without Exogenous Hormone Exposure

Hereditary angioedema (HAE) is characterized by recurrent attacks of skin and mucosal swelling in any part of the body including the digestive and respiratory tract which generally improve spontaneously within 12-72 hours. The underlying mechanism in HAE is related to bradykinin dysregulation which causes these attacks not to respond to common treatment strategies including epinephrine or corticosteroid. There are several types of HAE with different etiology but with the same clinical picture. Type 1 is due to the deficiency of C1 Inhibitor (C1- INH) protein and type 2 is related to dysfunctional C1-INH protein. The third type of HAE which comprises the minority of cases is associated with the normal amount and function of C1- INH protein. The presented case in this report was a 15-years old girl with a history of spontaneous angioedema attacks from the age of 14. The frequency of attacks was initially every two months but consequently increased to every two weeks after using some hormonal medications for ovarian cyst. Each episode has lasted around 10 days without any symptoms in between. Complement studies including C4, C1q, and C1-INH protein, both quantitative and qualitative, were reported as normal. A genetic assessment revealed a mutation in the exon 9 on the gene related to factor XII, hence the diagnosis of HAE type 3 was confirmed. This was a rare type of angioedema with normal amount and function of C1-INH protein which is predominantly seen in women during periods of imbalanced estrogen increments like pregnancy, lactation, and menopause, and hence it is responsive to hormonal manipulation strategies such as the use of progesterone containing medications.

EFFECTIVE MANAGEMENT OF ARTAVA KASHAYA BY AYURVEDA: A CASE REPORT

A female patient of 25 years of age came to OPD of National institute of Ayurveda, Jaipur on 22 September, 2020 with chief complaint of delayed menstruation with scanty flow since 4.5 years. Methodology: Detailed history with all necessary clinical, physical examination and laboratory investigations were carried out. No gross physical and chemical abnormality was found. All the laboratory investigations (including USG and hormonal analysis) were found to be normal. So the treatment was planned according to the symptoms. Diagnosis made on the basis on the basis of presenting complaints was Artava kashaya. Patient was treated with Tilashelukaravi kwatha for 2 consecutive cycles. Patient was kept on follow up for 1 cycle after cessation of Tilashelukaravi kwatha. Result: Patient had got her menstruation regularly with normal duration while taking medicine. Also the amount of flow was also improved and intensity of pain was reduced effectively from moderate to mild. Even after cessation of medicine she got her menstruation in 30 days with normal amount of flow.

Prenatal diagnostic and management of megacystis microcolon intestinal hypoperistalsis syndrome: A report on a rare case in Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Megacystis Microcolon Intestinal Hypoperistalsis Syndrome (MMIHS) is a rare and the most severe form of functional intestinal obstruction in the newborn. The characteristic features of this congenital and fatal disease are abdominal distension, absent or decreased bowel peristalsis. Abdominal distension is a consequence of the distended, unobstructed urinary bladder with or without hydro nephrosis. Some previous reports have revealed that the typical antenatal sonographic findings are as follows: a greatly distended bladder, bilateral hydro nephrosis, and a normal amount of amniotic fluid; however, the antenatal diagnosis of this syndrome is occasionally difficult.

Effect of Mutations on mRNA and Globin Stability: The Cases of Hb Bernalda/Groene Hart and Hb Southern Italy

We identified two unstable variants in the third exon of α-globin genes: Hb Bernalda/Groene Hart (HBA1:c.358C>T), and Hb Caserta (HBA2:c.79G>A) in cis to Hb Sun Prairie (HBA2:c.391G>C), also named Hb Southern Italy. These mutations occurred in the H helix of the α-globin that is involved in heme contacting, specific recognition of α-hemoglobin-stabilizing protein (AHSP), and α1β1 interactions. The carriers showed α-thalassemia phenotype, but one also jaundice and cholelithiasis. Molecular identification of clusters of families in Southern Italy encouraged molecular characterization of mRNA, globin chain analyses, molecular modeling studies, and comparison with globin variants to understand the mechanisms causing the α-thalassemia phenotype. A normal amount of Hb Bernalda/Groene Hart mRNA were found, and molecular modeling highlighted additional H bonds with AHSP. For Hb Southern Italy, showing an unexpected α/β biosynthetic ratio typical of the β-thalassemia type, two different molecular mechanisms were shown: Reduction of the variant mRNA, likely due to the No-Go Decay for the presence of unused triplet ACG at cod 26, and protein instability due to the impairment of AHSP interaction. The UDP glucuronosyltransferase 1A (UGT1A1) genotyping was conclusive in the case of jaundice and cholelithiasis. Multiple approaches are needed to properly identify the mechanisms leading to unstable variants and the effect of a mutation.

Environment Classification for Unmanned Aerial Vehicle Using Convolutional Neural Networks

Environment classification is one of the most critical tasks for Unmanned Aerial Vehicles (UAV). Since water accumulation may destabilize UAV, clouds must be detected and avoided. In a previous work presented by the authors, Superpixel Segmentation (SPS) descriptors with low computational cost are used to classify ground, sky, and clouds. In this paper, an enhanced approach to classify the environment in those three classes is presented. The proposed scheme consists of a Convolutional Neural Network (CNN) trained with a dataset generated by both, an human expert and a Support Vector Machine (SVM) to capture context and precise localization. The advantage of using this approach is that the CNN classifies each pixel, instead of a cluster like in SPS, which improves the resolution of the classification, also, is less tedious for the human expert to generate a few training samples instead of the normal amount that it is required. This proposal is implemented for images obtained from video and photographic cameras mounted on a UAV facing in the same direction of the vehicle flight. Experimental results and comparison with other approaches are shown to demonstrate the effectiveness of the algorithm.

Perancangan Perangkat Penghitung Jumlah Penumpang Pada Kapal Komersial Menggunakan Mikrokontroller

One of the factors that caused the ship accident because the amount of passengers on the ship exceeded capacity. The absence of a device directly used on the ship's door to counter the amount of passengers is the cause of the excess capacity of passengers on the ship. The purpose of this study is to counter the amount of passengers on commercial vessels either entering or exiting the same door and controlling the excess amount of passengers. This passenger counter device uses two IR Obstacle sensors which function to detect and count the amount of passengers entering and exiting on the ship. The sensor reading distance is 0.1 cm to 56 cm. The result of IR Obstacle sensor reading as a passenger detector will be processed using a mini computer Arduino uno displayed on the LCD as the amount of passengers. This device is equipped with LED indicators to indicate the amount of passengers on the ship. For the condition the amount of passengers exceeds the capacity then the alarm will be active and the ship starter can not be activated and for normal amount of passengers the alarm is off and the ship engine stater can be activated.