Successful Outcome After Intralesional Curettage for Spindle Cell Hemangioma of Fibula in an Infant: A Case Report

Spindle cell hemangioma (SCH), a non-neoplastic reactive vascular lesion, rarely locates in bones. We herein report a successful case of intralesional curettage for an infant with SCH of fibula. An 11-month-old boy was admitted to our center with a painless mass in the right proximal calf. Preoperative digital radiograph demonstrated a massive vascular lesion with an irregular bone destruction of proximal fibula. The lesion was removed via the intralesional curettage approach and pathologically diagnosed as SCH. The patient gained bone structure recovery of right proximal fibula. Two years after the surgery, he experienced no local recurrence. For the management of SCH of fibula with partial bone destruction, we suggest early-stage intralesional curettage as its safety and effectiveness.

Download Full-text

Successful outcome after intralesional curettage for spindle cell hemangioma of fibula: a case report

10.21203/rs.3.rs-379859/v1 ◽

2021 ◽

Author(s):

Rufa Wang ◽

Tao Han ◽

Xiaoguang Zhou

Keyword(s):

Bone Structure ◽

Early Stage ◽

Bone Destruction ◽

Vascular Lesion ◽

Successful Outcome ◽

Intralesional Curettage ◽

Proximal Fibula ◽

Successful Case ◽

Digital Radiograph ◽

Painless Mass

Abstract BackgroundSpindle cell hemangioma (SCH), a non-neoplastic reactive vascular lesion, rarely locates in bones. We herein report a successful case of intralesional curettage for an infant with SCH of fibula.Case presentationA 11-month-old male patient was admitted to our center with a painless mass in right proximal calf. Preoperative digital radiograph demonstrated a massive vascular lesion with an irregular bone destruction of proximal fibula. The lesion was removed via the intralesional curettage approach and pathologically diagnosed as SCH. After the surgery, the patient gained bone structure recovery of right proximal fibula. Two years after the surgery, he experienced no local recurrence.ConclusionFor the management of SCH of fibula with partial bone destruction, we suggest early-stage intralesional curettage as its safety and effectiveness.

Download Full-text

Spindle Cell Hemangioma in the Mucosa of the Upper Lip: A Case Report and Review of the Literature

Case Reports in Dentistry ◽

10.1155/2018/1370701 ◽

2018 ◽

Vol 2018 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Kazuhiro Murakami ◽

Kazuhiko Yamamoto ◽

Tsutomu Sugiura ◽

Tadaaki Kirita

Keyword(s):

Factor Viii ◽

Spindle Cell ◽

Wilms Tumor ◽

Smooth Muscle Actin ◽

Neck Region ◽

Surgical Excision ◽

Vascular Lesion ◽

Upper Lip ◽

Mixed Cell ◽

Spindle Cell Hemangioma

Spindle cell hemangioma (SCH) is a unique benign vascular lesion. We present a case of SCH in the upper lip of a 41-year-old woman. A submucosal nodular mass 30 × 20 mm in size was observed in the left upper lip. The mass developed 5 years earlier and enlarged after repeated ethanol injections. The mass was elastic firm, mobile, bluish in color, and well demarcated in magnetic resonance imaging. Under the clinical diagnosis of hemangioma, surgical excision was performed under local anesthesia. Microscopically, the lesion was composed of irregular cavernous spaces and multiple solid cellular areas. Cavernous spaces were filled with a mix of erythrocytes and organizing thrombi. The solid areas showed proliferation of spindle-shaped cells arranged haphazardly or in short interlacing fascicles. Immunohistochemically, most cells strongly reacted with vimentin. CD31, CD34, factor VIII, smooth muscle actin, and Wilms tumor-1 reacted with endothelial cells lining the cavernous spaces. The cells within solid areas consisted of mixed cell population with variable reaction for the markers except for factor VIII. From these findings, the diagnosis of SCH was made. Two years after surgery, no recurrence was noted. A review of SCH in the head and neck region is made.

Download Full-text

Retinol, α-Tocopherol and Vitamin D3 in White MuscleDisease

Medycyna Weterynaryjna ◽

10.21521/mw.6029 ◽

2018 ◽

Vol 74 (1) ◽

pp. 6029-2018

Author(s):

HANDAN MERT ◽

SERKAN YİLDİRİM ◽

IBRAHİM HAKKİ YORUK ◽

KİVANC IRAK ◽

BAHAT COMBA ◽

...

Keyword(s):

Vitamin A ◽

Vitamin D3 ◽

White Muscle ◽

Bone Structure ◽

Early Stage ◽

Vitamin A Deficiency ◽

Muscle Disease ◽

Control Group ◽

White Muscle Disease ◽

Fat Soluble Vitamins

Vitamins are essential for the health of all living organisms. Vitamins E, A, D and K are known as fat-soluble vitamins, and deprivation of vitamin E causes various disorders, especially in the reproduction and cardiovascular systems and in muscle functions. Vitamin A, on the other hand, has roles in various biological functions – like eyesight – and the growth, reproduction and differentiation of epithelial cells. Vitamin A deficiency leads to the keratinization of the epithelium, and disorders related to the metaplasies of the genital and genitourinary systems. Conversely, vitamin D is defined as a pro-hormone and is responsible for Cahomeostasis, and thus indirectly affects the bone metabolism, bone structure, and cellular and neural functions of Ca. White muscle disease (WMD) can occur in newborn lambs, but is more commonly seen in lambs of up to 3 months of age. In this study, 30 lambs of 3 to 50-days-old from different flocks diagnosed with White Muscle Disease (WMD) were selected as research material, while the control group consisted of 8 healthy lambs. With the aim of clarifying the cause of WMD, serum fat-soluble vitamins, retinol, α-tocopherol and vitamin D3 levels were determined in 16 lambs. Gluteal and heart musclet issue samples also were taken from 30 lambs with WMD. The vitamin levels of the samples were analysed by HPLC. The levels of serum α-tocopherol, retinols, and vitamin D3 were foundto be low in the diseased animals, but only retinol (p<0.001) and α-tocopherol (p<0.0011) level differences were statistically relevant. Macroscopically, Zenker’s necrosis was determined in the heart muscles of 17 lambs, and in the gluteal and chest muscles of 6 lambs. 7 lambs displayed necrosis in both their heart and in gluteal muscles. The samples were analyzed microscopically to reach similar findings: swollen homogeneous pink muscles, pycnotic nuclei, and hyperaemic and haemorrhagic blood vessels in gluteal, chest and heart muscles. Hyaline degeneration and Zenker's necrosis, dystrophic regions in necrotic areas, cc was detected as a severe disease in lambs at an early stage of life with advanced degeneration in different muscle tissues. Deficiency of fat-soluble vitamins was also detected in the sick animals. Control group lambs had higher levels of α tocopherol and retinol (p<0.001) compared to the sick lambs. .

Download Full-text

An infantile alantoaxial dislocation with patent foramen ovale managed with titanium cabling and allogenic bone grafts

Pediatric Reports ◽

10.4081/pr.2018.7339 ◽

2018 ◽

Vol 10 (1) ◽

Author(s):

Seidu A. Richard ◽

Zhi Gang Lan ◽

Xiao Yang ◽

Siqing Huang

Keyword(s):

Action Potentials ◽

Patent Foramen Ovale ◽

Early Stage ◽

Sensory Nerve ◽

Odontoid Process ◽

Bone Destruction ◽

Lower Limbs ◽

Foramen Ovale ◽

Compound Muscle Action Potentials ◽

Patient Reported

Atlantoaxial dislocation is a disorder that is characterized with loss of stability of the atlas and axis (C1-C2) with consequential loss of usual articulation. Although this condition is very common, no one has reported a case as young as our patients. We present a 7-month infant with bilateral paralysis of the lower limbs for four (4) months with no history of trauma. Computer tomographic (CT-scan) imaging revealed alantoaxial dislocation with severe cervical spinal cord compression. The odontoid process is displaced outwardly with no bone destruction. Doppler echocardiogram done revealed patent foramen ovale. Thorough physical examination as well as radiological evaluation revealed no feather malformations. Electrophysio - logical studies reveal normal compound muscle action potentials (CMAP) and sensory nerve action potentials (SNAPs) in all the limbs. Electromyography (EMG) also revealed normal nerves in the limbs and the trunk. We attained a stable fusion and anatomical reduction using a posterior titanium wire and an iliac bone graft harvested from his mother. This is the youngest patient reported in literature. Infantile alantoaxial dislocation should be managed at early stage to prevent long-term neurologic disorders.

Download Full-text

Spindle cell/sclerosing rhabdomyosarcoma with intracranial invasion without destroying the bone of the skull base: a case report and literature review

Acta Radiologica Open ◽

10.1177/2058460117727316 ◽

2017 ◽

Vol 6 (8) ◽

pp. 205846011772731

Author(s):

Daichi Momosaka ◽

Osamu Togao ◽

Akio Hiwatashi ◽

Koji Yamashita ◽

Koji Yoshimoto ◽

...

Keyword(s):

Spindle Cell ◽

Bone Destruction ◽

Japanese Woman ◽

World Health ◽

Imaging Characteristics ◽

The World ◽

Sclerosing Rhabdomyosarcoma ◽

Elderly Japanese ◽

Health Organization ◽

Worse Prognosis

Spindle cell/sclerosing rhabdomyosarcoma (ssRMS) is a new subtype of rhabdomyosarcoma included in the World Health Organization soft tissue and bone tumor classification in 2013. Despite the increasing number of reported cases of ssRMS, the imaging characteristics of ssRMS are not established. Herein, we present the case of an elderly Japanese woman with ssRMS of the masticator space with intracranial invasion without destruction of the adjacent bone. Attention should be paid to the presence of intracranial infiltration that may indicate a worse prognosis. Tumor growth without bone destruction could be a key finding to differentiate ssRMSs from conventional subtypes of rhabdomyosarcoma.

Download Full-text

Рентґенологічна характеристика ефективності лікування котів, хворих на гнійний остеомієліт

Вісник Полтавської державної аграрної академії ◽

10.31210/visnyk2013.02.44 ◽

2013 ◽

pp. 169-172

Author(s):

Т. М. Собчишина

Keyword(s):

Effective Treatment ◽

Bone Structure ◽

Early Stage ◽

X Ray ◽

Reparative Osteogenesis

Наведено дані рентґенологічних досліджень післязастосування ґранульованих імплантантів Біомін-гТлС для пластики кісткових дефектів. Встанов-лено, що застосування цих імплантантів призво-дить до активізації процесів репаративного ос-теогенезу та відтворення анатомічної форми йструктури кістки. Рентґенологічно виявлені таописані основні зміни тканин, характерні для ос-теомієліту. Доведено, що рентґенологічне дослі-дження дає можливість діагностувати остеоміє-літ на ранній стадії та призначити ефективнелікування. The data of X-ray after the application of granular implants Biomin-hTlS of bone defects.Found that the use of these implants leads to activation of reparative osteogenesis and playanatomic shape and bone structure. Radiologically detected and describes the main tissue changescharacteristic of osteomyelitis. It is shown that the X-ray study allows to diagnose osteomyelitis atan early stage and be an effective treatment.

Download Full-text