scholarly journals Functional and Mood Outcomes in Bipolar Disorder Patients With and Without Substance Use Disorders Undergoing Psychotherapy

2021 ◽  
Vol 12 ◽  
Author(s):  
William Moot ◽  
Marie Crowe ◽  
Maree Inder ◽  
Kate Eggleston ◽  
Christopher Frampton ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Substance Use ◽  
Social Adjustment ◽  
Functional Outcomes ◽  
Secondary Analysis ◽  
Adjunctive Treatment ◽  
Life Score ◽  
The Social ◽  
Negative Effect ◽  
Social Rhythm

Objectives: Research suggests that patients with co-morbid bipolar disorder (BD) and substance use disorder (SUD) have a poorer illness course and clinical outcome. The evidence is limited as SUD patients are often excluded from BD studies. In particular, evidence regarding long term outcomes from studies using psychotherapies as an adjunctive treatment is limited. We therefore examined data from two studies of Interpersonal Social Rhythm Therapy (IPSRT) for BD to determine whether lifetime or current SUD affected outcomes.Methods: Data were analyzed from two previous clinical trials of IPSRT for BD patients. Change in scores on the Social Adjustment Scale (SAS) from 0 to 78 weeks and cumulative mood scores from 0 to 78 weeks, measured using the Life Interval Follow-Up Evaluation (LIFE), were analyzed.Results: Of 122 patients (non-SUD n = 67, lifetime SUD but no current n = 43, current SUD n = 12), 79 received IPSRT and 43 received a comparison therapy—specialist supportive care—over 18 months. Lifetime SUD had a significant negative effect on change in SAS score but not LIFE score. There was no effect of current SUD on either change in score. Secondary analysis showed no correlation between symptom count and change in SAS total score or LIFE score.Conclusion: Current SUD has no impact on mood or functional outcomes, however, current SUD numbers were small, limiting conclusions. Lifetime SUD appears to be associated with impaired functional outcomes from psychotherapy. There is limited research on co-morbid BD and SUD patients undergoing psychotherapy.

Psychosocial interventions for bipolar disorder

2009 ◽  
Vol 21 (6) ◽  
pp. 275-284 ◽  
Author(s):  
David J. Castle ◽  
Lesley Berk ◽  
Sue Lauder ◽  
Michael Berk ◽  
Greg Murray
Keyword(s):  
Bipolar Disorder ◽  
Substance Use ◽  
Psychosocial Interventions ◽  
Behavioural Therapy ◽  
Psychosocial Treatments ◽  
Cognitive Behavioural ◽  
Bipolar Ii ◽  
Social Rhythm ◽  
Family Based ◽  
Randomised Controlled

Aim:To provide a selected overview of the literature on psychosocial treatments for bipolar disorderMethod:Selective literature reviewResults:Randomised controlled trials of psychosocial interventions in bipolar disorder fall largely into five categories, namely: psychoeducation, integrated treatments, family based therapy, cognitive behavioural therapy and interpersonal social rhythm therapy. Most studies have shown some benefit in terms of relapse prevention, but have tended to be effective for either the depressed or the manic pole, and not both. Broader outcome parameters such as quality of life have not been reported consistently. The mechanisms whereby treatments might exert their effects have not been clearly delineated. Many studies have excluded patients with bipolar II and other variants, and those with psychiatric and substance use comorbidities, reducing their generalisability.Discussion:Whilst psychosocial treatments show promise in the area of bipolar disorder, more work is required to delineate the effective elements of such interventions, and to ensure generalisability to individuals with bipolar II and other forms of bipolar disorder, as well as those with psychiatric and substance use comorbidities. Other forms of delivery, such as via the internet, deserve further exploration.

Social Adjustment in Bipolar and Unipolar Single-Episode and Recurrently Depressed Inpatients

2000 ◽  
Vol 86 (3_part_2) ◽  
pp. 1123-1126 ◽  
Author(s):  
Stella Dorz ◽  
Guido Magni ◽  
Sabrina Cognolato ◽  
Donatella Conforti ◽  
Antonio Luciano Fiorellini ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Major Depression ◽  
Social Adjustment ◽  
Single Episode ◽  
The Social ◽  
Social Adjustment Scale

Social adjustment scores were compared using the Social Adjustment scale for 24 inpatients with single-episode major depression, 72 with recurrent major depression, and 28 with bipolar disorder. There were no differences between the three groups either in overall score or on single scales.

scholarly journals Automatic detection of social rhythms in bipolar disorder

2016 ◽  
Vol 23 (3) ◽  
pp. 538-543 ◽  
Author(s):  
Saeed Abdullah ◽  
Mark Matthews ◽  
Ellen Frank ◽  
Gavin Doherty ◽  
Geri Gay ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Root Mean Square Error ◽  
Mean Square Error ◽  
Root Mean Square ◽  
High Accuracy ◽  
Sensor Data ◽  
Mean Square ◽  
Improve Performance ◽  
The Social ◽  
Social Rhythm

Objective To evaluate the feasibility of automatically assessing the Social Rhythm Metric (SRM), a clinically-validated marker of stability and rhythmicity for individuals with bipolar disorder (BD), using passively-sensed data from smartphones. Methods Seven patients with BD used smartphones for 4 weeks passively collecting sensor data including accelerometer, microphone, location, and communication information to infer behavioral and contextual patterns. Participants also completed SRM entries using a smartphone app. Results We found that automated sensing can be used to infer the SRM score. Using location, distance traveled, conversation frequency, and non-stationary duration as inputs, our generalized model achieves root-mean-square-error of 1.40, a reasonable performance given the range of SRM score (0–7). Personalized models further improve performance with mean root-mean-square-error of 0.92 across users. Classifiers using sensor streams can predict stable (SRM score ≥3.5) and unstable (SRM score <3.5) states with high accuracy (precision: 0.85 and recall: 0.86). Conclusions Automatic smartphone sensing is a feasible approach for inferring rhythmicity, a key marker of wellbeing for individuals with BD.

Social Adjustment in Bipolar and Unipolar Single-Episode and Recurrently Depressed Inpatients

2000 ◽  
Vol 86 (3_suppl) ◽  
pp. 1123-1126 ◽  
Author(s):  
Stella Dorz ◽  
Guido Magni ◽  
Sabrina Cognolato ◽  
Donatella Conforti ◽  
Antonio Luciano Fiorellini ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Major Depression ◽  
Social Adjustment ◽  
Single Episode ◽  
The Social ◽  
Social Adjustment Scale

Social adjustment scores were compared using the Social Adjustment Scale for 24 inpatients with single-episode major depression, 72 with recurrent major depression, and 28 with bipolar disorder. There were no differences between the three groups either in overall score or on single scales.

scholarly journals N-acetylcysteine for major depressive episodes in bipolar disorder

2011 ◽  
Vol 33 (4) ◽  
pp. 374-378 ◽  
Author(s):  
Pedro V Magalhães ◽  
Olívia M Dean ◽  
Ashley I Bush ◽  
David L Copolov ◽  
Gin S Malhi ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Depressive Symptoms ◽  
Functional Outcomes ◽  
Controlled Trial ◽  
Secondary Analysis ◽  
Randomised Clinical Trial ◽  
Outcome Data ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes

OBJECTIVE: In this report, we aimed to evaluate the effect of add-on N-acetylcysteine (NAC) on depressive symptoms and functional outcomes in bipolar disorder. To that end, we conducted a secondary analysis of all patients meeting full criteria for a depressive episode in a placebo controlled trial of adjunctive NAC for bipolar disorder. METHOD: Twenty-four week randomised clinical trial comparing adjunctive NAC and placebo in individuals with bipolar disorder experiencing major depressive episodes. Symptomatic and functional outcome data were collected over the study period. RESULTS: Seventeen participants were available for this report. Very large effect sizes in favor of NAC were found for depressive symptoms and functional outcomes at endpoint. Eight of the ten participants on NAC had a treatment response at endpoint; the same was true for only one of the seven participants allocated to placebo. DISCUSSION: These results indicate that adjunctive NAC may be useful for major depressive episodes in bipolar disorder. Further studies designed to confirm this hypothesis are necessary.

History of Abuse, Substance Use Problems, and Bipolar Disorder in a County Jail Setting

2008 ◽  
Author(s):  
Edwin Shirley ◽  
Lisa Stines Doane ◽  
Toyomi Goto ◽  
Norah Feeny ◽  
Sara M. Debanne ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Substance Use ◽  
County Jail ◽  
Substance Use Problems ◽  
History Of

The path of support-to-sales: mediating role of seller collaborative information exchange in social commerce

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Li Chen ◽  
Fengxia Zhu ◽  
Murali Mantrala
Keyword(s):  
Information Exchange ◽  
Instrumental Support ◽  
Trade Volume ◽  
Social Commerce ◽  
Content Type ◽  
Mediating Role ◽  
The Social ◽  
Source Data ◽  
Negative Effect

Purpose This paper aims to systematically investigate the direct and indirect effects of four types of support – peer instrumental support, peer emotional support, platform business support and platform communication support – on seller trade volume in social commerce. It also aims to uncover the path of support-to-sales of the seller from a platform perspective and provides a more complete picture of the social commerce phenomenon. Design/methodology/approach This paper uses multi-source data including primary survey data and secondary data on trade volume to test the hypotheses. PROCESS mediation model is used to analyze the multi-source data set. Findings This study finds that the positive effects of peer instrumental support, platform business support and platform communication support on seller trade volume are fully mediated by seller collaborative information exchange. Also, peer emotional support has a significant negative effect on seller trade volume and collaborative information exchange can serve as a buffer to mitigate the negative effect. Research limitations/implications The authors provide new insights into what types of support are or are not conducive to improving transaction volume of individual sellers and highlight the mediating role of seller information exchange in this value generation process in social commerce. These findings advance current knowledge of how seller interactions increase value in social commerce. The chosen research setting may limit the generalizability of the findings of this study. Practical implications This paper offers valuable implications for social commerce platforms on how to better serve their sellers to achieve high growth. Specifically, the findings suggest that platforms should encourage instrumental support and information exchange among peer sellers. In addition, platforms should expand seller support from a single-focus on sellers’ business to a dual-focus on both sellers’ business and socialization in social commerce. Originality/value This paper fulfills an identified need to study how sellers can better derive value from the social interactions and how social commerce platforms can effectively influence transactions, support sales and serve as a selling platform.

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