scholarly journals Clinical Features, Neuropsychology and Neuroimaging in Bipolar and Borderline Personality Disorder: A Systematic Review of Cross-Diagnostic Studies

2021 ◽  
Vol 12 ◽  
Author(s):  
Anna Massó Rodriguez ◽  
Bridget Hogg ◽  
Itxaso Gardoki-Souto ◽  
Alicia Valiente-Gómez ◽  
Amira Trabsa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Interpersonal Relationships ◽  
Clinical Features ◽  
Explanatory Power ◽  
Borderline Personality ◽  
Neuropsychological Performance ◽  
Diagnostic Studies ◽  
Co Morbidity

Background: Bipolar Disorder (BD) and Borderline Personality Disorder (BPD) have clinically been evolving as separate disorders, though there is still debate on the nosological valence of both conditions, their interaction in terms of co-morbidity or disorder spectrum and their distinct pathophysiology.Objective: The objective of this review is to summarize evidence regarding clinical features, neuropsychological performance and neuroimaging findings from cross-diagnostic studies comparing BD and BPD, to further caracterize their complex interplay.Methods: Using PubMed, PsycINFO and TripDataBase, we conducted a systematic literature search based on PRISMA guidelines of studies published from January 1980 to September 2019 which directly compared BD and BPD.Results: A total of 28 studies comparing BD and BPD were included: 19 compared clinical features, 6 neuropsychological performance and three neuroimaging abnormalities. Depressive symptoms have an earlier onset in BPD than BD. BD patients present more mixed or manic symptoms, with BD-I differing from BPD in manic phases. BPD patients show more negative attitudes toward others and self, more conflictive interpersonal relationships, and more maladaptive regulation strategies in affective instability with separate pathways. Impulsivity seems more a trait in BPD rather than a state as in BD. Otherwise, BD and BPD overlap in depressive and anxious symptoms, dysphoria, various abnormal temperamental traits, suicidal ideation, and childhood trauma. Both disorders differ and share deficits in neuropsychological and neuroimaging findings.Conclusion: Clinical data provide evidence of overlapping features in both disorders, with most of those shared symptoms being more persistent and intense in BPD. Thus, categorical classifications should be compared to dimensional approaches in transdiagnostic studies investigating BPD features in BD regarding their respective explanatory power for individual trajectories.Systematic Review Registration: The search strategy was pre-registered in PROSPERO: CRD42018100268.

scholarly journals A systematic review of the factors associated with the course of borderline personality disorder symptoms in adolescence

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Gabriele Skabeikyte ◽  
Rasa Barkauskiene
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Strong Support ◽  
Borderline Personality ◽  
Developmental Pathways ◽  
Eligibility Criteria ◽  
Factors Associated ◽  
Prospective Longitudinal

Abstract Background Research on personality pathology in adolescence has accelerated during the last decade. Among all of the personality disorders, there is strong support for the validity of borderline personality disorder (BPD) diagnosis in adolescence with comparable stability as seen in adulthood. Researchers have put much effort in the analysis of the developmental pathways and etiology of the disorder and currently are relocating their attention to the identification of the possible risk factors associated with the course of BPD symptoms during adolescence. The risk profile provided in previous systematic reviews did not address the possible development and course of BPD features across time. Having this in mind, the purpose of this systematic review is to identify the factors that are associated with the course of BPD symptoms during adolescence. Methods Electronic databases were systematically searched for prospective longitudinal studies with at least two assessments of BPD as an outcome of the examined risk factors. A total number of 14 articles from the period of almost 40 years were identified as fitting the eligibility criteria. Conclusions Factors associated with the course of BPD symptoms include childhood temperament, comorbid psychopathology, and current interpersonal experiences. The current review adds up to the knowledge base about factors that are associated with the persistence or worsening of BPD symptoms in adolescence, describing the factors congruent to different developmental periods.

Shame in Borderline Personality Disorder: Meta-Analysis

2021 ◽  
Vol 35 (Supplement A) ◽  
pp. 149-161
Author(s):  
Tzipi Buchman-Wildbaum ◽  
Zsolt Unoka ◽  
Robert Dudas ◽  
Gabriella Vizin ◽  
Zsolt Demetrovics ◽  
...  
Keyword(s):  
Systematic Review ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Meta Analysis ◽  
Education Level ◽  
Borderline Personality ◽  
Healthy Controls ◽  
Moderator Variables ◽  
Core Feature ◽  
Ptsd Symptomatology

Shame has been found to be a core feature of borderline personality disorder (BPD). To date, there is no existing systematic review or meta-analysis examining shame in individuals with BPD as compared to healthy controls (HCs). A meta-analysis of 10 studies comparing reported shame in BPD patients to HCs was carried out. Demographic and clinical moderator variables were included to see if they have a relationship with the effect size. Results showed that those with BPD had more reported shame than healthy controls. In addition, in BPD patients and HCs, higher education level was related to lower reported shame. In HCs, it was found that those who were younger reported a higher level of shame. Finally, among BPD patients, there was a relationship between levels of reported shame and elevated PTSD symptomatology. These findings emphasize the clinical relevance of shame in individuals with BPD and the need to formulate psychotherapeutic strategies that target and decrease shame.

The Relationship Between Cognitive Abilities and Trait Clinical Features in Patients With Borderline Personality Disorder

2021 ◽  
Vol 35 (5) ◽  
pp. 730-749
Author(s):  
Martino Belvederi Murri ◽  
Federica Folesani ◽  
Silvia Costa ◽  
Bruno Biancosino ◽  
Luigi Zerbinati ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Clinical Features ◽  
Cognitive Functions ◽  
Borderline Personality ◽  
Brief Symptom Inventory ◽  
Structure Questionnaire ◽  
Healthy Controls ◽  
Personality Dysfunction ◽  
The Relationship

Very few studies have focused on the relationship between cognitive functions and clinical features in borderline personality disorder (BPD). Subjects with BPD and healthy controls were administered the Repeatable Battery for the Assessment of Neuropsychological Status, Trail Making Test A and B, and the Wisconsin Card Sorting Test. The Brief Symptom Inventory (BSI-53) was used to assess the severity of current symptoms. Attachment style was assessed with the Experiences in Close Relationship Questionnaire, identity integration with the Personality Structure Questionnaire, and other domains of personality dysfunction with the RUDE Scale for Personality Dysfunction. Patients with BPD performed significantly worse than healthy controls in all cognitive domains. Cognitive functions, particularly delayed memory and visuospatial abilities, displayed meaningful associations with trait-like clinical features, above the effect of global cognition and state psychopathology. These findings highlight the need to evaluate effects of cognitive rehabilitation on trait features among individuals with BPD.

scholarly journals THE BORDERLINE PERSONALITY DISORDER OF ANTONY IN THE DRAMA ANTONY AND CLEOPATRABY WILLIAM SHAKESPEARE

2018 ◽  
Vol 3 (01) ◽  
pp. 27-44
Author(s):  
Eny Suprihandani ◽  
Thea Jacinda
Keyword(s):  
Borderline Personality Disorder ◽  
William Shakespeare ◽  
Personality Disorder ◽  
Interpersonal Relationships ◽  
Sigmund Freud ◽  
Mental Disease ◽  
Borderline Personality ◽  
Antony And Cleopatra ◽  
Self Image ◽  
Psychoanalytic Approach

Literature can be analyzed from many perspectives and point of views. By using psychoanalytic approach, this paper attempts to analyze one of the Shakespearean’s characters, Antony in the drama Antony and Cleopatra. The objective is to prove whether Antony truly suffers from Borderline Personality Disorder. Borderline Personality Disorder (BPD) is a personality disorder whose essential features are a pattern of marked impulsivity and instability of affects, interpersonal relationships, and self-image. Psychoanalysis theory is a theory developed by Sigmund Freud that enables to analyze whether a person suffers from a certain mental disease. Using those approaches, the characterization of Antony can be analyzed from his words, thoughts and other character’s opinion about him and then compared to the symptoms of Borderline Personality Disorder (BPD) and then found if they are matched. That Antony suffers from Borderline Personality Disorder can be finally proved.

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