scholarly journals n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 806 ◽  
Author(s):  
María Rodríguez ◽  
Pilar G. Rebollar ◽  
Simona Mattioli ◽  
Cesare Castellini
Keyword(s):  
Current Knowledge ◽  
Reproductive Traits ◽  
Health Improvement ◽  
Animal Product ◽  
Chain Pufa ◽  
Enzyme Substrate ◽  
Normal Human ◽  
Long Chain ◽  
Oxidation Susceptibility

This review compares the effects of different n-3 polyunsaturated fatty acid (PUFA) sources on biological activity, physiological/reproductive endpoints, and health implications with a special emphasis on a rabbit case study. Linoleic acid (LA) and α-linolenic acid (ALA) are members of two classes of PUFAs, namely the n-6 and n-3 series, which are required for normal human health. Both are considered precursors of a cascade of molecules (eicosanoids), which take part in many biological processes (inflammation, vasoconstriction/vasodilation, thromboregulation, etc.). However, their biological functions are opposite and are mainly related to the form (precursor or long-chain products) in which they were administered and to the enzyme–substrate preference. ALA is widely present in common vegetable oils and foods, marine algae, and natural herbs, whereas its long-chain PUFA derivatives are available mainly in fish and animal product origins. Recent studies have shown that the accumulation of n-3 PUFAs seems mostly to be tissue-dependent and acts in a tissue-selective manner. Furthermore, dietary n-3 PUFAs widely affect the lipid oxidation susceptibility of all tissues. In conclusion, sustainable sources of n-3 PUFAs are limited and exert a different effect about (1) the form in which they are administered, precursor or derivatives; (2) their antioxidant protections; and (3) the purpose to be achieved (health improvement, physiological and reproductive traits, metabolic pathways, etc.).

Prospective enzymes for omega-3 PUFA biosynthesis found in endoparasitic classes within the phylum Platyhelminthes

2020 ◽  
Vol 94 ◽  
Author(s):  
D. Babaran ◽  
M.T. Arts ◽  
R.J. Botelho ◽  
S.A. Locke ◽  
J. Koprivnikar
Keyword(s):  
Parasite Species ◽  
De Novo ◽  
Genomic Data ◽  
Wide Distribution ◽  
Omega 3 ◽  
Free Living ◽  
Chain Pufa ◽  
Pufa Biosynthesis ◽  
Aquatic Food ◽  
Long Chain

Abstract The free-living infectious stages of macroparasites, specifically, the cercariae of trematodes (flatworms), are likely to be significant (albeit underappreciated) vectors of nutritionally important polyunsaturated fatty acids (PUFA) to consumers within aquatic food webs, and other macroparasites could serve similar roles. In the context of de novo omega-3 (n-3) PUFA biosynthesis, it was thought that most animals lack the fatty acid (FA) desaturase enzymes that convert stearic acid (18:0) into ɑ-linolenic acid (ALA; 18:3n-3), the main FA precursor for n-3 long-chain PUFA. Recently, novel sequences of these enzymes were recovered from 80 species from six invertebrate phyla, with experimental confirmation of gene function in five phyla. Given this wide distribution, and the unusual attributes of flatworm genomes, we conducted an additional search for genes for de novo n-3 PUFA in the phylum Platyhelminthes. Searches with experimentally confirmed sequences from Rotifera recovered nine relevant FA desaturase sequences from eight species in four genera in the two exclusively endoparasite classes (Trematoda and Cestoda). These results could indicate adaptations of these particular parasite species, or may reflect the uneven taxonomic coverage of sequence databases. Although additional genomic data and, particularly, experimental study of gene functionality are important future validation steps, our results indicate endoparasitic platyhelminths may have enzymes for de novo n-3 PUFA biosynthesis, thereby contributing to global PUFA production, but also representing a potential target for clinical antihelmintic applications.

scholarly journals n‐3 PUFA Supplementation Alters Retinal Very‐Long‐Chain‐PUFA Levels and Ratios in Diabetic Animal Models

2019 ◽  
Vol 63 (15) ◽  
pp. 1801058 ◽  
Author(s):  
Aruna Gorusupudi ◽  
Fu‐Yen Chang ◽  
Kelly Nelson ◽  
Gregory S. Hageman ◽  
Paul S. Bernstein
Keyword(s):  
Animal Models ◽  
Diabetic Animal ◽  
Pufa Supplementation ◽  
Chain Pufa ◽  
Long Chain

Dietary long-chain PUFA in the form of TAG or phospholipids influence lymph lipoprotein size and composition in piglets

Lipids ◽  
2002 ◽  
Vol 37 (10) ◽  
pp. 975-980 ◽  
Author(s):  
Laura Amate ◽  
Angel Gil ◽  
María Ramírez
Keyword(s):  
Chain Pufa ◽  
Lipoprotein Size ◽  
Long Chain

scholarly journals The Source of Long-Chain PUFA in Formula Supplements Does Not Affect the Fatty Acid Composition of Plasma Lipids in Full-Term Infants

2004 ◽  
Vol 134 (4) ◽  
pp. 868-873 ◽  
Author(s):  
Aleix Sala-Vila ◽  
Ana I. Castellote ◽  
Cristina Campoy ◽  
Montserrat Rivero ◽  
María Rodriguez-Palmero ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Plasma Lipids ◽  
Full Term ◽  
Term Infants ◽  
Chain Pufa ◽  
Long Chain

scholarly journals Maternal but Not Fetal FADS Gene Variants Modify the Association between Maternal Long-Chain PUFA Intake in Pregnancy and Birth Weight

2014 ◽  
Vol 144 (9) ◽  
pp. 1430-1437 ◽  
Author(s):  
Carolina Moltó-Puigmartí ◽  
Martien C. J. M. van Dongen ◽  
Pieter C. Dagnelie ◽  
Jogchum Plat ◽  
Ronald P. Mensink ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gene Variants ◽  
Pufa Intake ◽  
Chain Pufa ◽  
Long Chain ◽  
Pregnancy And Birth ◽  
In Pregnancy

scholarly journals Factors Influencing the Private Involvement in Urban Rail Public-Private Partnership Projects in China

2017 ◽  
Vol 17 (1) ◽  
pp. 90-106 ◽  
Author(s):  
Yongjian Ke ◽  
Weiya Hao ◽  
Huiping Ding ◽  
Yingying Wang
Keyword(s):  
Influencing Factors ◽  
Current Knowledge ◽  
Group Discussion ◽  
Risk Allocation ◽  
Financial Model ◽  
Urban Rail ◽  
Current Knowledge Base ◽  
Private Investors ◽  
Fiscal Pressure

Private investors have been encouraged to participate in the development and operation of urban rail projects in China through Public-Private Partnerships (PPPs), given the fact that subnational governments are suffering from urgent development demands and severe fiscal pressure. However, there is no formal assessment to determine the private involvement in a PPP project. This problem is particularly critical in the sector of urban rail, in which the huge investment cannot rely on the private sector alone. This study hence aimed to uncover and identify the influencing factors. Multiple research methods, including content analysis, case study and focus group discussion were adopted to achieve the research purpose. Seven types of influencing factors were identified, including project financial model, government fiscal commitment, risk allocation, public accountability, efficiency considerations, policy and regulations, and organisational marketing strategies. The findings add to the current knowledge base by uncovering the drivers behind private involvement in a PPP project. They are also beneficial for industry practitioners as a basis/checklist to determine the private involvement.

Sign in / Sign up

Export Citation Format

Share Document