scholarly journals Performance of Fine-Tuning Convolutional Neural Networks for HEp-2 Image Classification

2020 ◽  
Vol 10 (19) ◽  
pp. 6940 ◽  
Author(s):  
Vincenzo Taormina ◽  
Donato Cascio ◽  
Leonardo Abbene ◽  
Giuseppe Raso

The search for anti-nucleus antibodies (ANA) represents a fundamental step in the diagnosis of autoimmune diseases. The test considered the gold standard for ANA research is indirect immunofluorescence (IIF). The best substrate for ANA detection is provided by Human Epithelial type 2 (HEp-2) cells. The first phase of HEp-2 type image analysis involves the classification of fluorescence intensity in the positive/negative classes. However, the analysis of IIF images is difficult to perform and particularly dependent on the experience of the immunologist. For this reason, the interest of the scientific community in finding relevant technological solutions to the problem has been high. Deep learning, and in particular the Convolutional Neural Networks (CNNs), have demonstrated their effectiveness in the classification of biomedical images. In this work the efficacy of the CNN fine-tuning method applied to the problem of classification of fluorescence intensity in HEp-2 images was investigated. For this purpose, four of the best known pre-trained networks were analyzed (AlexNet, SqueezeNet, ResNet18, GoogLeNet). The classifying power of CNN was investigated with different training modalities; three levels of freezing weights and scratch. Performance analysis was conducted, in terms of area under the ROC (Receiver Operating Characteristic) curve (AUC) and accuracy, using a public database. The best result achieved an AUC equal to 98.6% and an accuracy of 93.9%, demonstrating an excellent ability to discriminate between the positive/negative fluorescence classes. For an effective performance comparison, the fine-tuning mode was compared to those in which CNNs are used as feature extractors, and the best configuration found was compared with other state-of-the-art works.

Author(s):  
Mikhail Krinitskiy ◽  
Polina Verezemskaya ◽  
Kirill Grashchenkov ◽  
Natalia Tilinina ◽  
Sergey Gulev ◽  
...  

Polar mesocyclones (MCs) are small marine atmospheric vortices. The class of intense MCs, called polar lows, are accompanied by extremely strong surface winds and heat fluxes and thus largely influencing deep ocean water formation in the polar regions. Accurate detection of polar mesocyclones in high-resolution satellite data, while challenging, is a time-consuming task, when performed manually. Existing algorithms for the automatic detection of polar mesocyclones are based on the conventional analysis of patterns of cloudiness and involve different empirically defined thresholds of geophysical variables. As a result, various detection methods typically reveal very different results when applied to a single dataset. We develop a conceptually novel approach for the detection of MCs based on the use of deep convolutional neural networks (DCNNs). As a first step, we demonstrate that DCNN model is capable of performing binary classification of 500x500km patches of satellite images regarding MC patterns presence in it. The training dataset is based on the reference database of MCs manually tracked in the Southern Hemisphere from satellite mosaics. We use a subset of this database with MC diameters falling in the range of 200-400 km. This dataset is further used for testing several different DCNN setups, specifically, DCNN built “from scratch”, DCNN based on VGG16 pre-trained weights also engaging the Transfer Learning technique, and DCNN based on VGG16 with Fine Tuning technique. Each of these networks is further applied to both infrared (IR) and a combination of infrared and water vapor (IR+WV) satellite imagery. The best skills (97% in terms of the binary classification accuracy score) is achieved with the model that averages the estimates of the ensemble of different DCNNs. The algorithm can be further extended to the automatic identification and tracking numerical scheme and applied to other atmospheric phenomena characterized by a distinct signature in satellite imagery.


2019 ◽  
Vol 9 (11) ◽  
pp. 2183 ◽  
Author(s):  
Roger Fonollà ◽  
Thom Scheeve ◽  
Maarten R. Struyvenberg ◽  
Wouter L. Curvers ◽  
Albert J. de Groof ◽  
...  

Barrett’s esopaghagus (BE) is a known precursor of esophageal adenocarcinoma (EAC). Patients with BE undergo regular surveillance to early detect stages of EAC. Volumetric laser endomicroscopy (VLE) is a novel technology incorporating a second-generation form of optical coherence tomography and is capable of imaging the inner tissue layers of the esophagus over a 6 cm length scan. However, interpretation of full VLE scans is still a challenge for human observers. In this work, we train an ensemble of deep convolutional neural networks to detect neoplasia in 45 BE patients, using a dataset of images acquired with VLE in a multi-center study. We achieve an area under the receiver operating characteristic curve (AUC) of 0.96 on the unseen test dataset and we compare our results with previous work done with VLE analysis, where only AUC of 0.90 was achieved via cross-validation on 18 BE patients. Our method for detecting neoplasia in BE patients facilitates future advances on patient treatment and provides clinicians with new assisting solutions to process and better understand VLE data.


Author(s):  
Mikhail Krinitskiy ◽  
Polina Verezemskaya ◽  
Kirill Grashchenkov ◽  
Natalia Tilinina ◽  
Sergey Gulev ◽  
...  

Polar mesocyclones (MCs) are small marine atmospheric vortices. The class of intense MCs, called polar lows, are accompanied by extremely strong surface winds and heat fluxes and thus largely influencing deep ocean water formation in the polar regions. Accurate detection of polar mesocyclones in high-resolution satellite data, while challenging, is a time-consuming task, when performed manually. Existing algorithms for the automatic detection of polar mesocyclones are based on the conventional analysis of patterns of cloudiness and involve different empirically defined thresholds of geophysical variables. As a result, various detection methods typically reveal very different results when applied to a single dataset. We present a conceptually novel approach for the detection of MCs based on the use of deep convolutional neural networks (DCNNs). We demonstrate that DCNN model is capable of performing binary classification of 500x500km patches of satellite images regarding MC patterns presence in it. The training dataset is based on the reference database of MCs manually tracked in the Southern Hemisphere from satellite mosaics. This dataset is further used for testing several different DCNN setups, specifically, DCNN built “from scratch”, DCNN based on VGG16 pre-trained weights also engaging the Transfer Learning technique, and DCNN based on VGG16 with Fine Tuning technique. Each of these networks is further applied to both infrared (IR) and a combination of infrared and water vapor (IR+WV) satellite imagery. The best skills (97% in terms of the binary classification accuracy score) is achieved with the model that averages the estimates of the ensemble of different DCNNs. The algorithm can be further extended to the automatic identification and tracking numerical scheme and applied to other atmospheric phenomena characterized by a distinct signature in satellite imagery.


Author(s):  
Mohammad Amimul Ihsan Aquil ◽  
Wan Hussain Wan Ishak

<span id="docs-internal-guid-01580d49-7fff-6f2a-70d1-7893ec0a6e14"><span>Plant diseases are a major cause of destruction and death of most plants and especially trees. However, with the help of early detection, this issue can be solved and treated appropriately. A timely and accurate diagnosis is critical in maintaining the quality of crops. Recent innovations in the field of deep learning (DL), especially in convolutional neural networks (CNNs) have achieved great breakthroughs across different applications such as the classification of plant diseases. This study aims to evaluate scratch and pre-trained CNNs in the classification of tomato plant diseases by comparing some of the state-of-the-art architectures including densely connected convolutional network (Densenet) 120, residual network (ResNet) 101, ResNet 50, ReseNet 30, ResNet 18, squeezenet and Vgg.net. The comparison was then evaluated using a multiclass statistical analysis based on the F-Score, specificity, sensitivity, precision, and accuracy. The dataset used for the experiments was drawn from 9 classes of tomato diseases and a healthy class from PlantVillage. The findings show that the pretrained Densenet-120 performed excellently with 99.68% precision, 99.84% F-1 score, and 99.81% accuracy, which is higher compared to its non-trained based model showing the effectiveness of using a combination of a CNN model with fine-tuning adjustment in classifying crop diseases.</span></span>


Author(s):  
Mikhail Krinitskiy ◽  
Polina Verezemskaya ◽  
Kirill Grashchenkov ◽  
Natalia Tilinina ◽  
Sergey Gulev ◽  
...  

Polar mesocyclones (MCs) are small marine atmospheric vortices. The class of intense MCs, called polar lows, are accompanied by extremely strong surface winds and heat fluxes and thus largely influencing deep ocean water formation in the polar regions. Accurate detection of polar mesocyclones in high-resolution satellite data, while challenging, is a time-consuming task, when performed manually. Existing algorithms for the automatic detection of polar mesocyclones are based on the conventional analysis of patterns of cloudiness and involve different empirically defined thresholds of geophysical variables. As a result, various detection methods typically reveal very different results when applied to a single dataset. We present a conceptually novel approach for the detection of MCs based on the use of deep convolutional neural networks (DCNNs). We demonstrate that DCNN model is capable of performing binary classification of 500x500km patches of satellite images regarding MC patterns presence in it. The training dataset is based on the reference database of MCs manually tracked in the Southern Hemisphere from satellite mosaics. This dataset is further used for testing several different DCNN setups, specifically, DCNN built &ldquo;from scratch&rdquo;, DCNN based on VGG16 pre-trained weights also engaging the Transfer Learning technique, and DCNN based on VGG16 with Fine Tuning technique. Each of these networks is further applied to both infrared (IR) and a combination of infrared and water vapor (IR+WV) satellite imagery. The best skills (97% in terms of the binary classification accuracy score) is achieved with the model that averages the estimates of the ensemble of different DCNNs. The algorithm can be further extended to the automatic identification and tracking numerical scheme and applied to other atmospheric phenomena characterized by a distinct signature in satellite imagery.


Atmosphere ◽  
2018 ◽  
Vol 9 (11) ◽  
pp. 426 ◽  
Author(s):  
Mikhail Krinitskiy ◽  
Polina Verezemskaya ◽  
Kirill Grashchenkov ◽  
Natalia Tilinina ◽  
Sergey Gulev ◽  
...  

Polar mesocyclones (MCs) are small marine atmospheric vortices. The class of intense MCs, called polar lows, are accompanied by extremely strong surface winds and heat fluxes and thus largely influencing deep ocean water formation in the polar regions. Accurate detection of polar mesocyclones in high-resolution satellite data, while challenging, is a time-consuming task, when performed manually. Existing algorithms for the automatic detection of polar mesocyclones are based on the conventional analysis of patterns of cloudiness and they involve different empirically defined thresholds of geophysical variables. As a result, various detection methods typically reveal very different results when applied to a single dataset. We develop a conceptually novel approach for the detection of MCs based on the use of deep convolutional neural networks (DCNNs). As a first step, we demonstrate that DCNN model is capable of performing binary classification of 500 × 500 km patches of satellite images regarding MC patterns presence in it. The training dataset is based on the reference database of MCs manually tracked in the Southern Hemisphere from satellite mosaics. We use a subset of this database with MC diameters falling in the range of 200–400 km. This dataset is further used for testing several different DCNN setups, specifically, DCNN built “from scratch”, DCNN based on VGG16 pre-trained weights also engaging the Transfer Learning technique, and DCNN based on VGG16 with Fine Tuning technique. Each of these networks is further applied to both infrared (IR) and a combination of infrared and water vapor (IR + WV) satellite imagery. The best skills (97% in terms of the binary classification accuracy score) is achieved with the model that averages the estimates of the ensemble of different DCNNs. The algorithm can be further extended to the automatic identification and tracking numerical scheme and applied to other atmospheric phenomena that are characterized by a distinct signature in satellite imagery.


2019 ◽  
Vol 8 (2S11) ◽  
pp. 3677-3680

Dog Breed identification is a specific application of Convolutional Neural Networks. Though the classification of Images by Convolutional Neural Network serves to be efficient method, still it has few drawbacks. Convolutional Neural Networks requires a large amount of images as training data and basic time for training the data and to achieve higher accuracy on the classification. To overcome this substantial time we use Transfer Learning. In computer vision, transfer learning refers to the use of a pre-trained models to train the CNN. By Transfer learning, a pre-trained model is trained to provide solution to classification problem which is similar to the classification problem we have. In this project we are using various pre-trained models like VGG16, Xception, InceptionV3 to train over 1400 images covering 120 breeds out of which 16 breeds of dogs were used as classes for training and obtain bottleneck features from these pre-trained models. Finally, Logistic Regression a multiclass classifier is used to identify the breed of the dog from the images and obtained 91%, 94%,95% validation accuracy for these different pre-trained models VGG16, Xception, InceptionV3.


2020 ◽  
Vol 2020 (10) ◽  
pp. 28-1-28-7 ◽  
Author(s):  
Kazuki Endo ◽  
Masayuki Tanaka ◽  
Masatoshi Okutomi

Classification of degraded images is very important in practice because images are usually degraded by compression, noise, blurring, etc. Nevertheless, most of the research in image classification only focuses on clean images without any degradation. Some papers have already proposed deep convolutional neural networks composed of an image restoration network and a classification network to classify degraded images. This paper proposes an alternative approach in which we use a degraded image and an additional degradation parameter for classification. The proposed classification network has two inputs which are the degraded image and the degradation parameter. The estimation network of degradation parameters is also incorporated if degradation parameters of degraded images are unknown. The experimental results showed that the proposed method outperforms a straightforward approach where the classification network is trained with degraded images only.


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