Recent Advances in Understanding the Function of the PGIP Gene and the Research of Its Proteins for the Disease Resistance of Plants

Polygalacturonase-inhibiting protein (PGIP) is an important plant biochemical anti-disease factor. PGIP has a leucine-rich repeat structure that can selectively bind and inhibit the activity of endo-polygalacturonase (endo-PG) in fungi, playing a key role in plant disease resistance. The regulation of PGIP in plant disease resistance has been well studied, and the effect of PGIP to increase disease resistance is clear. This review summarizes recent advances in understanding the PGIP protein structure, the PGIP mechanism of plant disease resistance, and anti-disease activity by PGIP gene transfer. This overview should contribute to a better understanding of PGIP function and can help guide resistance breeding of PGIP for anti-disease effects.

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Genome editing for plant disease resistance: applications and perspectives

Philosophical Transactions of the Royal Society B Biological Sciences ◽

10.1098/rstb.2018.0322 ◽

2019 ◽

Vol 374 (1767) ◽

pp. 20180322 ◽

Cited By ~ 19

Author(s):

Kangquan Yin ◽

Jin-Long Qiu

Keyword(s):

Disease Resistance ◽

Genome Editing ◽

Plant Disease Resistance ◽

Genetic Improvement ◽

Plant Disease ◽

Resistance Breeding ◽

Global Food Security ◽

Yield And Quality ◽

Genome Modifications ◽

Global Food

Diseases severely affect crop yield and quality, thereby threatening global food security. Genetic improvement of plant disease resistance is essential for sustainable agriculture. Genome editing has been revolutionizing plant biology and biotechnology by enabling precise, targeted genome modifications. Editing provides new methods for genetic improvement of plant disease resistance and accelerates resistance breeding. Here, we first summarize the challenges for breeding resistant crops. Next, we focus on applications of genome editing technology in generating plants with resistance to bacterial, fungal and viral diseases. Finally, we discuss the potential of genome editing for breeding crops that present novel disease resistance in the future. This article is part of the theme issue ‘Biotic signalling sheds light on smart pest management’.

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RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes

Trends in Genetics ◽

10.1016/0168-9525(94)90104-x ◽

1994 ◽

Vol 10 (12) ◽

pp. 421 ◽

Cited By ~ 1

Keyword(s):

Arabidopsis Thaliana ◽

Disease Resistance ◽

Resistance Genes ◽

Plant Disease Resistance ◽

Plant Disease ◽

Disease Resistance Genes ◽

Leucine Rich Repeat ◽

Repeat Class ◽

Plant Disease Resistance Genes

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CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects

Briefings in Functional Genomics ◽

10.1093/bfgp/elz041 ◽

2020 ◽

Vol 19 (1) ◽

pp. 26-39 ◽

Cited By ~ 8

Author(s):

Shakeel Ahmad ◽

Xiangjin Wei ◽

Zhonghua Sheng ◽

Peisong Hu ◽

Shaoqing Tang

Keyword(s):

Disease Resistance ◽

Plant Disease Resistance ◽

Genetic Improvement ◽

Plant Disease ◽

Plant Pathogens ◽

Crop Improvement ◽

Resistance Breeding ◽

Conventional Breeding ◽

Global Food Security ◽

Genome Modifications

Abstract Several plant pathogens severely affect crop yield and quality, thereby threatening global food security. In order to cope with this challenge, genetic improvement of plant disease resistance is required for sustainable agricultural production, for which conventional breeding is unlikely to do enough. Luckily, genome editing systems that particularly clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9) has revolutionized crop improvement by enabling robust and precise targeted genome modifications. It paves the way towards new methods for genetic improvement of plant disease resistance and accelerates resistance breeding. In this review, the challenges, limitations and prospects for conventional breeding and the applications of CRISPR/Cas9 system for the development of transgene-free disease-resistant crops are discussed.

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