scholarly journals Special Issue on Diffuse Optical Spectroscopy: Advances towards Widespread Applications

2021 ◽  
Vol 11 (23) ◽  
pp. 11548
Author(s):  
Alberto Dalla Mora

Light is a powerful tool for the non-invasive and non-destructive analysis of several organic and inorganic materials [...]

2012 ◽  
Vol 39 (11) ◽  
pp. 813 ◽  
Author(s):  
Roland Pieruschka ◽  
Hendrik Poorter

No matter how fascinating the discoveries in the field of molecular biology are, in the end it is the phenotype that matters. In this paper we pay attention to various aspects of plant phenotyping. The challenges to unravel the relationship between genotype and phenotype are discussed, as well as the case where ‘plants do not have a phenotype’. More emphasis has to be placed on automation to match the increased output in the molecular sciences with analysis of relevant traits under laboratory, greenhouse and field conditions. Currently, non-destructive measurements with cameras are becoming widely used to assess plant structural properties, but a wider range of non-invasive approaches and evaluation tools has to be developed to combine physiologically meaningful data with structural information of plants. Another field requiring major progress is the handling and processing of data. A better e-infrastructure will enable easier establishment of links between phenotypic traits and genetic data. In the final part of this paper we briefly introduce the range of contributions that form the core of a special issue of this journal on plant phenotyping.


2018 ◽  
Vol 183 (suppl_1) ◽  
pp. 150-156
Author(s):  
Jesse H Lam ◽  
Thomas D O’Sullivan ◽  
Tim S Park ◽  
Jae H Choi ◽  
Robert V Warren ◽  
...  

Abstract Objective To quantitatively measure tissue composition and hemodynamics during resuscitative endovascular balloon occlusion of the aorta (REBOA) in two tissue compartments using non-invasive two-channel broadband diffuse optical spectroscopy (DOS). Methods Tissue concentrations of oxy- and deoxyhemoglobin (HbO2 and HbR), water, and lipid were measured in a porcine model (n = 10) of massive hemorrhage (65% total blood volume over 1 h) and 30-min REBOA superior and inferior to the aortic balloon. Results After hemorrhage, hemoglobin oxygen saturation (StO2 = HbO2/[HbO2 + HbR]) at both sites decreased significantly (−29.9% and −42.3%, respectively). The DOS measurements correlated with mean arterial pressure (MAP) (R2 = 0.79, R2 = 0.88), stroke volume (SV) (R2 = 0.68, R2 = 0.88), and heart rate (HR) (R2 = 0.72, R2 = 0.88). During REBOA, inferior StO2 continued to decline while superior StO2 peaked 12 min after REBOA before decreasing again. Inferior DOS parameters did not associate with MAP, SV, or HR during REBOA. Conclusions Dual-channel regional tissue DOS measurements can be used to non-invasively track the formation of hemodynamically distinct tissue compartments during hemorrhage and REBOA. Conventional systemic measures MAP, HR, and SV are uncorrelated with tissue status in inferior (downstream) sites. Multi-compartment DOS may provide a more complete picture of the efficacy of REBOA and similar resuscitation procedures.


CHEST Journal ◽  
2004 ◽  
Vol 126 (4) ◽  
pp. 874S
Author(s):  
Jennifer Armstrong ◽  
Jangwoen Lee ◽  
Andrew Duke ◽  
Hamza Beydoun ◽  
Kelly Kreuter ◽  
...  

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Mila Andonova

AbstractThis study proposes non-destructive assessment instrumentation, the X-ray MicroCT scanning, to evaluate archaeological basketry remains prior to any destructive analysis. Three case studies are originating from two archaeological sites in Southeast Europe, with three different stages of preservation (poor, sufficient and very good). In addition, there are two preservation modes—charring and desiccation—along with two conservation situations: treated and untreated with conservation agent fragments. The three different scenarios were chosen to explore the potential range of X-ray MicroCT scanning technology when applied to monocotyledonous small-sized archaeological remains. It was proved that this non-invasive X-ray method is particularly suitable for the often-disadvantaged ancient basketry remains.


2005 ◽  
Vol 53 (1) ◽  
pp. S113.2-S113
Author(s):  
K. Kreuter ◽  
J. Lee ◽  
J. Armstrong ◽  
B. Tromberg ◽  
S. Mahon ◽  
...  

2020 ◽  
Vol 10 (8) ◽  
pp. 2752
Author(s):  
Yoko Hoshi

In 1977, Jöbsis first described the in vivo application of near-infrared spectroscopy (NIRS) [...]


Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Tiffany S Ko ◽  
Wensheng Guo ◽  
Constantine D Mavroudis ◽  
Ryan W Morgan ◽  
Wesley M Baker ◽  
...  

Introduction: We have shown that during CPR, novel non-invasive monitoring of cerebral tissue oxygenation (StO 2 , %) and total hemoglobin concentration (THC, μmol/L) by frequency-domain diffuse optical spectroscopy (FD-DOS) is associated with ROSC in a swine model of pediatric cardiac arrest. Our objective is to find the optimal non-invasive predictor for ROSC and assess feasibility of a stable critical threshold over time in early CPR. Hypothesis: Stable critical thresholds with high sensitivity or specificity for ROSC may be established in early CPR (<10 min) from non-invasive cerebral StO 2 and THC measurements initiated at CPR start. Methods: One-month-old swine (n=31) underwent 7 minutes of asphyxia, induction of ventricular fibrillation, and up to 20 minutes of CPR till ROSC or death (no ROSC). Absolute StO 2 and THC and absolute and relative change from 1 minute into CPR (time for chest molding and FD-DOS placement) were evaluated as ROSC predictors over time. For each variable, an ROC curve and two critical thresholds, maximizing specificity (=1) or sensitivity (=1), were determined at 1-min intervals from 2-10 minutes of CPR using univariate logistic regression. Optimal predictor was selected by highest mean AUC. A stable specificity or sensitivity threshold was feasible if the mean threshold had a specificity or sensitivity >0.9 over all intervals, respectively. Results: Absolute change in StO 2 (ΔStO 2 ) had the highest mean (SD) AUC of 0.90 (0.07). Consistently >0.8, the AUC exceeded 0.9 after 7 minutes of CPR ( see Fig. ). The mean specificity threshold (ΔStO 2 = +5.1%) and sensitivity threshold (ΔStO 2 = +1.4%) achieved an overall specificity of 0.93 and sensitivity of 0.98, respectively. Conclusions: Non-invasive monitoring of absolute change in StO 2 was most predictive of ROSC and stable critical thresholds with high specificity or sensitivity were established in early CPR. Future work will independently validate this promising tool for CPR optimization.


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