scholarly journals Medical Devices for Tremor Suppression: Current Status and Future Directions

Biosensors ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 99
Author(s):  
Jiancheng Mo ◽  
Ronny Priefer
Keyword(s):  
Medical Devices ◽  
Daily Living ◽  
Physical Activities ◽  
Current Status ◽  
Future Directions ◽  
Surgical Interventions ◽  
Tremor Suppression ◽  
Surgical Treatments ◽  
Deep Brain

Tremors are the most prevalent movement disorder that interferes with the patient’s daily living, and physical activities, ultimately leading to a reduced quality of life. Due to the pathophysiology of tremor, developing effective pharmacotherapies, which are only suboptimal in the management of tremor, has many challenges. Thus, a range of therapies are necessary in managing this progressive, aging-associated disorder. Surgical interventions such as deep brain stimulation are able to provide durable tremor control. However, due to high costs, patient and practitioner preference, and perceived high risks, their utilization is minimized. Medical devices are placed in a unique position to bridge this gap between lifestyle interventions, pharmacotherapies, and surgical treatments to provide safe and effective tremor suppression. Herein, we review the mechanisms of action, safety and efficacy profiles, and clinical applications of different medical devices that are currently available or have been previously investigated for tremor suppression. These devices are primarily noninvasive, which can be a beneficial addition to the patient’s existing pharmacotherapy and/or lifestyle intervention.

scholarly journals Medical and surgical interventions to improve the quality of life for endometriosis patients: a systematic review

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Maurizio Nicola D’Alterio ◽  
Stefania Saponara ◽  
Mirian Agus ◽  
Antonio Simone Laganà ◽  
Marco Noventa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
English Language ◽  
Short Form ◽  
Work And Family ◽  
Surgical Interventions ◽  
Medline Search ◽  
Accessible Information ◽  
Before And After ◽  
Surgical Treatments

AbstractEndometriosis impairs the quality of life (QoL) of many women, including their social relationships, daily activity, productivity at work, and family planning. The aim of this review was to determine the instruments used to examine QoL in previous clinical studies of endometriosis and to evaluate the effect of medical and surgical interventions for endometriosis on QoL. We conducted a systematic search and review of studies published between January 2010 and December 2020 using MEDLINE. Search terms included “endometriosis” and “quality of life.” We only selected studies that used a standardized questionnaire to evaluate QoL before and after medical or surgical interventions. Only articles in the English language were examined. The initial search identified 720 results. After excluding duplicates and applying inclusion criteria, 37 studies were selected for analysis. We found that the two scales most frequently used to measure QoL were the Short Form-36 health survey questionnaire (SF-36) and the Endometriosis Health Profile-30 (EHP-30). Many medical and surgical treatments demonstrated comparable benefits in pain control and QoL improvement. There is no clear answer as to what is the best treatment for improving QoL because each therapy must be personalized for the patient and depends on the woman’s goals. In conclusion, women must be informed about endometriosis and given easily accessible information to improve treatment adherence and their QoL.

Surgical treatment of rectovaginal fistulas (systematic literature review)

2021 ◽  
pp. 30-48
Author(s):  
Andrei Anatolevich Mudrov ◽  
Aleksandr Yur’evich Titov ◽  
Mariyam Magomedovna Omarova ◽  
Sergei Alekseevich Frolov ◽  
Ivan Vasilevich Kostarev ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Meta Analysis ◽  
High Recurrence Rate ◽  
Surgical Interventions ◽  
Rectovaginal Fistulas ◽  
Surgical Treatments

Despite the large number of available surgical interventions aimed at the treatment of rectovaginal fistulas, the results of their use remain extremely disappointing, associated with the high recurrence rate of the disease reaching 80 %, as well as the lack of a single tactic to minimize the risk of anal incontinence and the need for colostomy. Objective: to conduct a systematic literature review in order to summarize information related to the rectovaginal fistulas surgery. The systematic review includes the results of an analysis of 97 clinical trials selected from 756 publications found in databases. Inclusion criteria: a full-text article, the presence of at least 5 patients in the study, as well as data on the outcome of surgery. Clinical trials with different surgical treatments were identified and classified into the following categories: elimination of the rectovaginal septal defect with a displaced flap (rectal and vaginal); Martius surgery; gracilis muscle transposition; transperineal procedure; abdominal procedure including endoscopic and laparoscopic methods; use of biological or biocompatible materials. Treatment outcomes vary significantly from 0 % to > 80 %. None of the studies were randomized. Due to the low quality of the identified studies, comparison of results and meta-analysis conduction were not possible. Conclusion: as a result of the systematic review, data for the analysis and development of any strategic and tactical algorithms for the treatment of RVF were not obtained. The most important questions still remain open: what and when surgical method to choose, is it necessary to form a disconnecting stoma?

Assessment of the Effects of Unilateral Electrode Dysfunction in Patients With Parkinson Disease Undergoing Bilateral Subthalamic Nucleus Deep Brain Stimulation

2011 ◽  
Vol 70 (suppl_1) ◽  
pp. ons163-ons169
Author(s):  
Young Seok Park ◽  
Joo Pyung Kim ◽  
Won Seok Chang ◽  
Phil Hyu Lee ◽  
Young Ho Sohn ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Deep Brain Stimulation ◽  
Activities Of Daily Living ◽  
Parkinson Disease ◽  
Daily Living ◽  
Motor Score ◽  
Stn Dbs ◽  
Updrs Motor Score ◽  
Deep Brain

Abstract BACKGROUND: Bilateral subthalamic nucleus deep brain stimulation (STN-DBS) is the gold standard surgical treatment for medically intractable Parkinson disease, and unilateral electrodes are reported to have beneficial effects. However, assessment of patients after electrode failure needs to be established. OBJECTIVE: To assess the effects of the remaining unilateral electrode in Parkinson disease after bilateral STN-DBS. METHODS: Between May 2000 and March 2009, 8 patients had unilateral STN-DBS after bilateral STN-DBS. We assessed clinical outcome by comparing the Unified Parkinson Disease Rating Scale (UPDRS) motor score, activities of daily living, levodopa-equivalent daily dosages, and quality of life according to the Short-Form 36 Health Survey between patients with unilateral and bilateral electrodes. RESULTS: Although ipsilateral and axial UPDRS motor scores were compromised, UPDRS motor scores contralateral to the side of the implant remained unaltered after removal of 1 electrode. Although physical aspects of quality of life declined significantly with a unilateral electrode, pain and social functioning were not significantly affected. No significant changes in activities of daily living, Hoehn and Yahr stage, or levodopa-equivalent daily dosage were observed after removal of 1 electrode. CONCLUSION: The UPDRS motor score with unilateral STN-DBS was compromised relative to bilateral STN-DBS for ipsilateral motor and axial symptoms. When 1 electrode is compromised, revision of that electrode will eventually be required, but not immediately in all patients. If a patient tolerates loss of 1 electrode according to motor score while maintaining activities of daily living and quality of life, it is possible to wait and observe the situation instead of immediately revising the electrode.

scholarly journals Percutaneous Management of Malignant Biliary Strictures: Current Status and Future Directions

2017 ◽  
Vol 01 (01) ◽  
pp. 036-046
Author(s):  
Mohammed Attaya ◽  
Hosam Attaya ◽  
Ashraf Thabet
Keyword(s):  
New Technologies ◽  
Current Status ◽  
Biliary Strictures ◽  
Biliary Stents ◽  
Future Directions ◽  
Improve Patient Survival ◽  
Percutaneous Interventions ◽  
Improve Patient ◽  
Transhepatic Biliary Drainage

AbstractVarious minimally invasive percutaneous interventions may be performed for the treatment and management of malignant biliary obstruction. The types of percutaneous interventions include percutaneous transhepatic biliary drainage, percutaneous cholecystostomy, and biliary stent placement. Biliary stents have undergone continued evolution in design to prolong patency, increase cost-effectiveness, improve patient survival, and quality of life. Furthermore, investigational techniques, such as radiofrequency ablation, intraluminal brachytherapy, and photodynamic therapy promise new technologies in the field of biliary intervention. This review focuses on the current status of percutaneous therapies for malignant biliary strictures and obstruction.

Deep brain stimulation as an effective treatment option for post–midbrain infarction-related tremor as it presents with Benedikt syndrome

2008 ◽  
Vol 109 (4) ◽  
pp. 635-639 ◽  
Author(s):  
S. Kathleen Bandt ◽  
Douglas Anderson ◽  
Jose Biller
Keyword(s):  
Daily Living ◽  
Red Nucleus ◽  
Cerebral Peduncle ◽  
Oculomotor Nucleus ◽  
Intention Tremor ◽  
Effective Treatment Option ◽  
Deep Brain Stimulator ◽  
Midbrain Infarction ◽  
Deep Brain

Benedikt syndrome is a rare but debilitating constellation of symptoms that manifests from infarction of the red nucleus, cerebral peduncle, oculomotor fascicles, and lower oculomotor nucleus. Clinically, it presents as ipsilateral cranial nerve III palsy, contralateral hemiataxia with intention tremor, contralateral hemiparesis, and hyperactive tendon reflexes. Commonly, the tremor upon purposeful movement proves to be the most debilitating manifestation of the infarction with significant impact on the patient's ability to perform activities of daily living and, therefore, quality of life. The authors report the successful management of this debilitating post–midbrain infarction tremor with the insertion of a deep brain stimulator with targets in the contralateral lenticular fasciculus.

Quality-of-Life Research in Acne Vulgaris: Current Status and Future Directions

2019 ◽  
Vol 20 (4) ◽  
pp. 527-538 ◽  
Author(s):  
Servando E. Marron ◽  
Pavel V. Chernyshov ◽  
Lucia Tomas-Aragones
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Current Status ◽  
Future Directions ◽  
Quality Of Life Research

scholarly journals Neuromodulation for the treatment of eating disorders and obesity

2017 ◽  
Vol 8 (2) ◽  
pp. 73-92 ◽  
Author(s):  
Darrin J. Lee ◽  
Gavin J.B. Elias ◽  
Andres M. Lozano
Keyword(s):  
Quality Of Life ◽  
Morbid Obesity ◽  
Eating Disorders ◽  
Brain Stimulation ◽  
Poor Quality ◽  
Current Status ◽  
Potential Treatment ◽  
Non Invasive ◽  
Deep Brain

Eating disorders and obesity adversely affect individuals both medically and psychologically, leading to reduced life expectancy and poor quality of life. While there exist a number of treatments for anorexia, morbid obesity and bulimia, many patients do not respond favorably to current behavioral, medical or bariatric surgical management. Neuromodulation has been postulated as a potential treatment for eating disorders and obesity. In particular, deep brain stimulation and transcranial non-invasive brain stimulation have been studied for these indications across a variety of brain targets. Here, we review the neurobiology behind eating and eating disorders as well as the current status of preclinical and clinical neuromodulation trials for eating disorders and obesity.

Quality of life evaluation in sarcoidosis: current status and future directions

2008 ◽  
Vol 14 (5) ◽  
pp. 470-477 ◽  
Author(s):  
David E Victorson ◽  
David Cella ◽  
Marc A Judson
Keyword(s):  
Quality Of Life ◽  
Current Status ◽  
Future Directions ◽  
Life Evaluation
Sign in / Sign up

Export Citation Format

Share Document