scholarly journals A Fluorescence-Based Wireless Capsule Endoscopy System for Detecting Colorectal Cancer

Cancers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 890 ◽  
Author(s):  
Mohammad Wajih Alam ◽  
Seyed Shahim Vedaei ◽  
Khan A. Wahid

Wireless capsule endoscopy (WCE) has been widely used in gastrointestinal (GI) diagnosis that allows the physicians to examine the interior wall of the human GI tract through a pain-free procedure. However, there are still several limitations of the technology, which limits its functionality, ultimately limiting its wide acceptance. Its counterpart, the wired endoscopic system is a painful procedure that demotivates patients from going through the procedure, and adversely affects early diagnosis. Furthermore, the current generation of capsules is unable to automate the detection of abnormality. As a result, physicians are required to spend longer hours to examine each image from the endoscopic capsule for abnormalities, which makes this technology tiresome and error-prone. Early detection of cancer is important to improve the survival rate in patients with colorectal cancer. Hence, a fluorescence-imaging-based endoscopic capsule that automates the detection process of colorectal cancer was designed and developed in our lab. The proof of concept of this endoscopic capsule was tested on porcine intestine and liquid phantom. The proposed WCE system offers great possibilities for future applicability in selective and specific detection of other fluorescently labelled cancers.

2016 ◽  
Vol 28 (04) ◽  
pp. 1650029 ◽  
Author(s):  
Pedram Salehpour ◽  
Hossein Balazadeh Bahar ◽  
Ghader Karimian ◽  
Hossein Ebrahimnezhad

Wireless capsule endoscopy (WCE) has been proven to be a robust technology which is able to ease diagnosing the GI tract diseases. It can be seen that a better computational algorithm is needed to analyze WCE images. Ulcer is one of the several diseases which are diagnosed using these images. Non-uniform lighting can complicate the detection process because it can change the color of tissue and make it seem darker or lighter than usual. This change of color makes the detection harder as the main feature of detecting ulcer as the color of the tissue. In this research work, adapted bit-planes are used to detect useful areas in images and then two sets of features, bit-plane probability and wavelet-based features, were extracted from the detected areas and used to classify them. Experimental results demonstrate a promising ground for further analysis of the channel-based bit-plane data and wavelet-based features.


Author(s):  
Amira S. Ashour ◽  
Nilanjan Dey ◽  
Waleed S. Mohamed ◽  
Jolanda G. Tromp ◽  
R. Simon Sherratt ◽  
...  

Wireless Capsule Endoscopy (WCE) is a highly promising technology for gastrointestinal (GI) tract abnormality diagnosis. However, low image resolution and low frame rates are challenging issues in WCE. In addition, the relevant frames containing the features of interest for accurate diagnosis only constitute 1% of the complete video information. For these reasons, analyzing the WCE videos is still a time consuming and laborious examination for the gastroenterologists, which reduces WCE system usability. This leads to the emergent need to speed-up and automates the WCE video process for GI tract examinations. Consequently, the present work introduced the concept of WCE technology, including the structure of WCE systems, with a focus on the medical endoscopy video capturing process using image sensors. It discussed also the significant characteristics of the different GI tract for effective feature extraction. Furthermore, video approaches for bleeding and lesion detection in the WCE video were reported with computer-aided diagnosis systems in different applications to support the gastroenterologist in the WCE video analysis. In image enhancement, WCE video review time reduction is also discussed, while reporting the challenges and future perspectives, including the new trend to employ the deep learning models for feature Learning, polyp recognition, and classification, as a new opportunity for researchers to develop future WCE video analysis techniques.


2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Guobing Pan ◽  
Litong Wang

Wireless capsule endoscopy (WCE) offers a feasible noninvasive way to detect the whole gastrointestinal (GI) tract and revolutionizes the diagnosis technology. However, compared with wired endoscopies, the limited working time, the low frame rate, and the low image resolution limit the wider application. The progress of this new technology is reviewed in this paper, and the evolution tendencies are analyzed to be high image resolution, high frame rate, and long working time. Unfortunately, the power supply of capsule endoscope (CE) is the bottleneck. Wireless power transmission (WPT) is the promising solution to this problem, but is also the technical challenge. Active CE is another tendency and will be the next geneion of the WCE. Nevertheless, it will not come true shortly, unless the practical locomotion mechanism of the active CE in GI tract is achieved. The locomotion mechanism is the other technical challenge, besides the challenge of WPT. The progress about the WPT and the active capsule technology is reviewed.


Author(s):  
Md. Abdullah Al Rakib ◽  
◽  
Shamim Ahmad ◽  
Tareq Mohammad Faruqi ◽  
Mainul Haque ◽  
...  

This paper focuses to design a compact (110mm³) Ultra-Wide Band (UWB) (3.1GHz to 10.6GHz) antenna, which covers almost the whole 10dB impedance matching bandwidth of the UWB range. Two of the main specialties of this article over other related articles are its antenna’s wider bandwidth (approx. 7.3GHz) and antenna’s simulation environment. No other papers consider such a realistic model to simulate their antenna, before. Due to its wider bandwidth, this antenna can be employed in the Wireless Capsule Endoscopy (WCE) system, which mainly requires a high-speed real-time data transfer-capable antenna. The antenna was examined inside simplified human Gastrointestinal (GI) tract phantoms (Colon, Esophagus, Small Intestine and Stomach) as well as the human Voxel GI tract model by maintaining proper tissue properties for the sake of accurate parametric results. Biocompatible material polyimide was used to construct the capsule wall to fulfill the system’s biocompatibility. In the result analysis part, the proposed antenna’s SAR (Specific Absorption Rate) or electromagnetic energy amount, consumed by near-side body tissue was considered and found in the acceptable region, according to Federal Communication Commission (FCC)’s regulation. Also, other crucial antenna parameters such as VSWR, reflection coefficient, radiation characteristics, efficiencies, directivity and surface current density were adoptable compare to other related articles. The Finite Integration Technique (FIT) of CST Microwave Studio Suite 2020 was used to investigate the antenna parameters.


Endoscopy ◽  
2006 ◽  
Vol 38 (11) ◽  
Author(s):  
P McConville ◽  
WJ Cash ◽  
RGP Watson ◽  
JS Collins

2017 ◽  
Vol 26 (2) ◽  
pp. 151-156
Author(s):  
Manuele Furnari ◽  
Andrea Buda ◽  
Gabriele Delconte ◽  
Davide Citterio ◽  
Theodor Voiosu ◽  
...  

Background & Aims: Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms with unclear etiology that may show functioning or non-functioning features. Primary tumor localization often requires integrated imaging. The European Neuroendocrine Tumors Society (ENETS) guidelines proposed wireless-capsule endoscopy (WCE) as a possible diagnostic tool for NETs, if intestinal origin is suspected. However, its impact on therapeutic management is debated. We aimed to evaluate the yield of WCE in detecting intestinal primary tumor in patients showing liver NET metastases when first-line investigations are inconclusive.Method: Twenty-four patients with histological diagnosis of metastatic NET from liver biopsy and no evidence of primary lesions at first-line investigations were prospectively studied in an ENETS-certified tertiary care center. Wireless-capsule endoscopy was requested before explorative laparotomy and intra-operative ultrasound. The diagnostic yield of WCE was compared to the surgical exploration.Results: Sixteen subjects underwent surgery; 11/16 had positive WCE identifying 16 bulging lesions. Mini-laparotomy found 13 NETs in 11/16 patients (9 small bowel, 3 pancreas, 1 bile ducts). Agreement between WCE and laparotomy was recorded in 9 patients (Sensitivity=75%; Specificity=37.5%; PPV=55%; NPV=60%). Correspondence assessed per-lesions produced similar results (Sensitivity=70%; Specificity=25%; PPV=44%; NPV=50%). No capsule retentions were recorded.Conclusions: Wireless-capsule endoscopy is not indicated as second-line investigation for patients with gastro-entero-pancreatic NETs. In the setting of a referral center, it might provide additional information when conventional investigations are inconclusive about the primary site.Abbreviations: DBE: double balloon enteroscopy; GEP-NET: gastro-entero-pancreatic neuroendocrine tumor; GI: gastrointestinal; ENETS: European Neuroendocrine Tumor Society; NET: neuroendocrine tumor; SSRS: somatostatin receptor scintigraphy; WCE: wireless capsule endoscopy.


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