scholarly journals Adverse Childhood Experiences Are Associated with Reduced Psychological Resilience in Youth: A Systematic Review and Meta-Analysis

Children ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 27
Author(s):  
Cyleen A. Morgan ◽  
Yun-Hsuan Chang ◽  
Olivia Choy ◽  
Meng-Che Tsai ◽  
Shulan Hsieh
Keyword(s):  
Systematic Review ◽  
Health Outcomes ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Negative Association ◽  
Psychological Resilience ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
The Relationship ◽  
Negative Health Outcomes

Background: Adverse childhood experiences (ACEs) are presumed to influence internalizing and externalizing behaviors that can significantly debilitate long-term biopsychological development in individuals. Psychological resilience has been shown to effectively mediate the relationship between ACEs and negative health outcomes since individuals with low levels of resilience may have difficulty with bouncing back from toxic exposure to ACEs. Thus, the present systematic review and meta-analysis was aimed toward synthesizing current knowledge of the relationship between ACEs and psychological resilience in youths. Methods: A combination of key words relevant to the present study was searched on the PubMed, EMBASE, Scopus, Cochrane, and Google Scholar databases. The results were restricted to English publications and human studies, with subjects ranging between the age of 0 to 35 years. Effect-size measures inclusive of pooled correlation coefficients for correlation analyses and pooled odds ratios for regression analyses, respectively, were calculated using random-effect models to determine the relationship between ACEs and psychological resilience. Results: The searches identified 85 potentially relevant studies. Among them, 76 were excluded due to limited access, irrelevant data, and the fact that the variables of interest were not explicitly measured or disclosed, leaving a final total of nine studies considered valid for the meta-analysis. Findings from correlational meta-analysis (n = 6) revealed a significantly negative association between ACEs and resilience (β = −0.120 [−0.196, −0.043]). The meta-analysis of the studies (n = 3) reporting dichotomous outcomes (ACE ≥ 1 vs. no ACE) indicated that subjects who experienced an ACE were 63% less likely to display high resilience, in comparison to subjects without such experiences. Conclusion: Our results support a negative association between ACEs and psychological resilience and highlight the multiple dimensions that constitute resilience in an ACE-exposure context. These findings may be particularly useful to policy makers and healthcare institutions in terms of helping them devise effective medical interventions and community outreach programs intended to develop resilience in youths, thus reducing health-risk behaviors and negative health outcomes.

Adverse childhood experiences and risk of cancer during adulthood: A systematic review and meta-analysis

2021 ◽  
Vol 117 ◽  
pp. 105088
Author(s):  
Zhao Hu ◽  
Atipatsa Chiwanda Kaminga ◽  
Jun Yang ◽  
Jiefeng Liu ◽  
Huilan Xu
Keyword(s):  
Systematic Review ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Risk Of Cancer

Adverse childhood experiences and risk of type 2 diabetes: A systematic review and meta-analysis

Metabolism ◽  
2015 ◽  
Vol 64 (11) ◽  
pp. 1408-1418 ◽  
Author(s):  
Hao Huang ◽  
Peipei Yan ◽  
Zhilei Shan ◽  
Sijing Chen ◽  
Moying Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Experiences ◽  
Adverse Childhood

Systematic Review of Pediatric Health Outcomes Associated with Adverse Childhood Experiences (aces)*

2018 ◽  
Author(s):  
Debora L. Oh ◽  
Petra Jerman ◽  
Sara Silvério Marques ◽  
Kadiatou Koita ◽  
Allison Ipsen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Outcomes ◽  
Adverse Childhood Experiences ◽  
Childhood Experiences ◽  
Pediatric Health ◽  
Adverse Childhood

scholarly journals Adverse childhood experiences and chronic lung diseases in adulthood: a systematic review and meta-analysis

2020 ◽  
Vol 11 (1) ◽  
pp. 1720336 ◽  
Author(s):  
Samuel Lopes ◽  
Jaime Eduardo Cecilio Hallak ◽  
João Paulo Machado de Sousa ◽  
Flávia de Lima Osório
Keyword(s):  
Systematic Review ◽  
Adverse Childhood Experiences ◽  
Lung Diseases ◽  
Meta Analysis ◽  
Childhood Experiences ◽  
Chronic Lung Diseases ◽  
Adverse Childhood

scholarly journals Relationship between childhood socioeconomic position and adverse childhood experiences (ACEs): a systematic review

2019 ◽  
Vol 73 (12) ◽  
pp. 1087-1093 ◽  
Author(s):  
David Walsh ◽  
Gerry McCartney ◽  
Michael Smith ◽  
Gillian Armour
Keyword(s):  
Systematic Review ◽  
Socioeconomic Position ◽  
Adverse Childhood Experiences ◽  
Later Life ◽  
Cochrane Library ◽  
High Quality ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Increased Risk ◽  
The Relationship

Background‘Adverse childhood experiences’ (ACEs) are associated with increased risk of negative outcomes in later life: ACEs have consequently become a policy priority in many countries. Despite ACEs being highly socially patterned, there has been very little discussion in the political discourse regarding the role of childhood socioeconomic position (SEP) in understanding and addressing them. The aim here was to undertake a systematic review of the literature on the relationship between childhood SEP and ACEs.MethodsMEDLINE, PsycINFO, ProQuest and Cochrane Library databases were searched. Inclusion criteria were: (1) measurement of SEP in childhood; (2) measurement of multiple ACEs; (3) ACEs were the outcome; and (4) statistical quantification of the relationship between childhood SEP and ACEs. Search terms included ACEs, SEP and synonyms; a second search additionally included ‘maltreatment’. Overall study quality/risk of bias was calculated using a modified version of the Hamilton Tool.ResultsIn the ACEs-based search, only 6 out of 2825 screened papers were eligible for qualitative synthesis. The second search (including maltreatment) increased numbers to: 4562 papers screened and 35 included for synthesis. Eighteen papers were deemed ‘high’ quality, five ‘medium’ and the rest ‘low’. Meaningful statistical associations were observed between childhood SEP and ACEs/maltreatment in the vast majority of studies, including all except one of those deemed to be high quality.ConclusionLower childhood SEP is associated with a greater risk of ACEs/maltreatment. With UK child poverty levels predicted to increase markedly, any policy approach that ignores the socioeconomic context to ACEs is therefore flawed.PROSPERO registration numberCRD42017064781.

scholarly journals Identifying Targets for Substance Use Prevention in Young People Exposed to Childhood Adversity: Protocol for a Systematic Review (Preprint)

2020 ◽  
Author(s):  
Lucinda Rachel Grummitt ◽  
Erin Veronica Kelly ◽  
Emma Louise Barrett ◽  
Katherine M Keyes ◽  
Nicola Clare Newton
Keyword(s):  
Substance Use ◽  
Young People ◽  
Adverse Childhood Experiences ◽  
Meta Analysis ◽  
Childhood Adversity ◽  
Substance Use Prevention ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Quantitative Synthesis ◽  
The Relationship

BACKGROUND Adverse childhood experiences are prevalent robust risk factors for the development of substance use problems. However, less is known about the causal mechanisms that explain these relationships. While directly preventing adverse childhood experiences is ideal, it is not always possible. In such cases, the mechanisms themselves may be amenable to intervention, allowing for the effective prevention of problematic substance use among children exposed to adversity. Identifying such mechanisms is therefore a critical step for efforts aiming to reduce the high individual and societal burdens associated with substance use globally. OBJECTIVE This study aims to systematically identify and synthesize evidence on the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use outcomes in young people (age 10-24 years). METHODS A systematic review will be conducted using PubMed, MEDLINE, PsycINFO, Web of Science, and CINAHL databases to determine the modifiable mediators and moderators of the relationship between adverse childhood experiences and substance use in young people. Data from the review will be qualitatively synthesized, unless we identify a sufficient number of studies (at least five) that examine the same type of adversity (eg, physical or sexual abuse) and the same mediator/moderator, in which case a quantitative synthesis (meta-analysis) will be conducted. If a quantitative synthesis is warranted, standardized effect estimates of the indirect (mediated) effect between adverse childhood experiences and substance use outcomes will be combined using a random-effects meta-analysis. Mediators/moderators will be grouped according to a socioecological perspective, using the four levels of individual, interpersonal, community, and public policy/culture. RESULTS Electronic searches were completed in August 2019. A total of 4004 studies were included for screening after removing duplicates. After evaluating titles and abstracts against eligibility criteria, a further 3590 studies were excluded, leaving 415 studies for full-text screening. The results of the review are expected to be available by December 2020. CONCLUSIONS The mechanisms linking adverse childhood experiences and substance use outcomes in young people are vital targets for substance use prevention efforts. This review will provide evidence to inform the development of prevention strategies in order to interrupt the negative life trajectory that can begin with childhood adversity. CLINICALTRIAL PROSPERO International Prospective Register of Systematic Reviews CRD42020148773; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020148773 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/22368

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