scholarly journals Electrophilic Iodination of Organic Compounds Using Elemental Iodine or Iodides: Recent Advances 2008–2021: Part I

Compounds ◽  
2022 ◽  
Vol 2 (1) ◽  
pp. 3-24
Author(s):  
Njomza Ajvazi ◽  
Stojan Stavber
Keyword(s):  
Organic Chemistry ◽  
Organic Compounds ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Present Review ◽  
Active Compounds ◽  
Synthetic Organic Chemistry ◽  
Recent Advances ◽  
Elemental Iodine

The iodination of organic compounds is of great importance in synthetic organic chemistry. It opens comprehensive approaches for the synthesis of various biologically active compounds. The recent advances in iodination of organic compounds using elemental iodine or iodides, covering the last thirteen years, are the objective of the present review.

Recent Advances in the Green Synthesis of Heterocycles: From Building Blocks to Biologically Active Compounds

2021 ◽  
Vol 18 ◽  
Author(s):  
Christian Schäfer ◽  
Hyejin Cho ◽  
Bernadett Vlocskó ◽  
Guoshu Xie ◽  
Béla Török
Keyword(s):  
Green Synthesis ◽  
Building Blocks ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Environmentally Benign ◽  
Active Compounds ◽  
Aromatic Heterocycles ◽  
High Interest ◽  
Recent Advances ◽  
Benign Synthesis

: Recent advances in the environmentally benign synthesis of common heterocycles are described. This account features three main parts; the preparation of non-aromatic heterocycles, one-ring aromatic heterocycles and their condensed analogs. Due to the great variety of and high interest in these compounds, this work focuses on providing representative examples of the preparation of the target compounds.

The Use of Cinnamic Acid and Cinnamaldehyde, as Bio-Based Molecules, in Organic Synthesis and Preparation of Biologically Active Compounds

2020 ◽  
Vol 17 ◽  
Author(s):  
Anna S. Zalivatskaya ◽  
Dmitriy N. Zakusilo ◽  
Aleksander V. Vasilyev
Keyword(s):  
Biological Activity ◽  
Double Bond ◽  
Carbonyl Group ◽  
Organic Compounds ◽  
Organic Synthesis ◽  
Cinnamic Acid ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Platform Chemicals

: Cinnamic acid and cinnamaldehyde may be obtained from renewable plant bio-mass, Cinnamon plants, therefore these compounds should be considered as bio-based platform chemicals for synthesis of novel substances. This review describes recent achievements in organic synthesis based on transformations of cinnamaldehyde, cinnamic acid and its derivatives, focusing, mainly, on the preparation of biologically active compounds. Reactions of these cinnamic derivatives may proceed both onto carbon-carbon double bond and carbonyl group that allows obtaining a wide variety of organic compounds having high synthetic importance and different practically valuable properties, including biological activity.

scholarly journals Organocatalytic Name Reactions Enabled by NHCs

Materials ◽  
2020 ◽  
Vol 13 (16) ◽  
pp. 3574
Author(s):  
Krzysztof Dzieszkowski ◽  
Izabela Barańska ◽  
Karina Mroczyńska ◽  
Michał Słotwiński ◽  
Zbigniew Rafiński
Keyword(s):  
Organic Chemistry ◽  
Total Synthesis ◽  
Heterocyclic Carbenes ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Great Opportunity

Giving reactions the names of their discoverers is an extraordinary tradition of organic chemistry. Nowadays, this phenomenon is much rarer, although already named historical reactions are still often developed. This is also true in the case of a broad branch of N‑heterocyclic carbenes catalysis. NHCs allow many unique synthetic paths, including commonly known name reactions. This article aims to gather this extensive knowledge and compare historical reactions with current developed processes. Furthermore, this review is a great opportunity to highlight some of the unique applications of these procedures in the total synthesis of biologically active compounds. Hence, this concise article may also be a source of knowledge for scientists just starting their adventure with N‑heterocyclic carbene chemistry.

scholarly journals 1,3-Cyclohexadien-1-Als: Synthesis, Reactivity and Bioactivities

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1772
Author(s):  
Ignacio E. Tobal ◽  
Rocío Bautista ◽  
David Diez ◽  
Narciso M. Garrido ◽  
Pilar García-García
Keyword(s):  
Organic Chemistry ◽  
Building Block ◽  
Building Blocks ◽  
Natural Compounds ◽  
Diels Alder ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Complex Molecules ◽  
Active Compounds ◽  
Electron Withdrawing Group

In synthetic organic chemistry, there are very useful basic compounds known as building blocks. One of the main reactions wherein they are applied for the synthesis of complex molecules is the Diels–Alder cycloaddition. This reaction is between a diene and a dienophile. Among the most important dienes are the cyclic dienes, as they facilitate the reaction. This review considers the synthesis and reactivity of one of these dienes with special characteristics—it is cyclic and has an electron withdrawing group. This building block has been used for the synthesis of biologically active compounds and is present in natural compounds with interesting properties.

Sign in / Sign up

Export Citation Format

Share Document