scholarly journals Improved Transition Metal Dichalcogenides-Based Surface Plasmon Resonance Biosensors

2019 ◽  
Vol 4 (2) ◽  
pp. 49 ◽  
Author(s):  
Mohammad Hasibul Hasan Hasib ◽  
Jannati Nabiha Nur ◽  
Conrad Rizal ◽  
Kamrun Nahar Shushama

Surface plasmon resonance (SPR) biosensors based on transition metal dichalcogenides (TMDC) materials have shown improved performance in terms of sensitivity, detection accuracy (DA), and quality factor (QF) over conventional biosensors. In this paper, we propose a five-layers model containing black phosphorus (BP) and TMDC (Ag/BP/WS2) in Kretschmann configuration. Using TM-polarized light at 633 nm, we numerically demonstrate the highest sensitivity (375°/RIU), DA (0.9210), and QF (65.78 1/RIU) reported so far over similar materials. Refractive index (RI) of the coupling prism has also played an essential role in enhancing the performance of these biosensors. The research on TMDC materials is still new, and these materials bring about opportunities to develop a new class of biosensor.

2020 ◽  
Vol 18 (9) ◽  
pp. 711-718
Author(s):  
Rashmi Tiwari ◽  
Sachin Singh ◽  
R. K. Yadav ◽  
Pooja Lohia ◽  
D. K. Dwivedi

After the discovery of graphene in 2004, two-dimensional materials have attracted attention at large scale because of their peculiar structure and extraordinary properties. As they have large potential in future nano electronics, two-dimensional transition metal dichalcogenides has become most focus topic of study. Transition metal dichalcogenides with tunable finite band gap and significant transitional behavior are much suitable for the construction of electronic and optoelectronic devices of high-performance. However, platinum diselenide is group-10 transition metal dichalcogenides which occur naturally in one phase transition, which has been theoretically predicted as an excellent material. The proposed structure of surface plasmon resonance (SPR) -based biosensor consists of a silicon and two-dimensional nanomaterial platinum diselenide. The performance parameters of proposed biosensor (surface plasmon resonance-based) such as detection accuracy, figure of merit, sensitivity, full width at half maximum have been investigated. The sensitivity, detection accuracy, full width half maximum and figure of merit of proposed surface plasmon resonance biosensor having silver (50 nm), silicon (2 nm) and one layer of platinum diselenide with 2 nm thickness at 633 nm wavelength is 2200RIU–1 , 0.20 deg–1, 4.980 and 44.22 RIU–1 respectively. Silicon sheet is used in the middle of the Ag and platinum diselenide to prevent the oxidation of silver and enhance the sensitivity of platinum diselenide based surface plasmon resonance biosensor. The sensitivity of conventional surface plasmon resonance biosensor and the proposed surface plasmon resonance biosensor without silicon layer is 1700RIU–1 and 2000RIU–1 respectively. Surface plasmon resonance biosensor of device structure CaF2/Ag/Si/PtSe2 has higher sensitivity in comparison to device structures CaF2/Ag (conventional) and CaF2/Ag/PtSe2 (without Silicon Layer) by 29.41% and 10% respectively. Although the highest sensitivity obtained is 2620RIU–1 for 60 nm silver with 3 nm silicon layer except the platinum diselenide layer.


Micromachines ◽  
2020 ◽  
Vol 11 (8) ◽  
pp. 779
Author(s):  
Sachin Singh ◽  
Pravin Kumar Singh ◽  
Ahmad Umar ◽  
Pooja Lohia ◽  
Hasan Albargi ◽  
...  

The absorption and binding energy of material plays an important role with a large surface area and conductivity for the development of any sensing device. The newly grown 2D nanomaterials like black phosphorus transition metal dichalcogenides (TMDCs) or graphene have excellent properties for sensing devices’ fabrication. This paper summarizes the progress in the area of the 2D nanomaterial-based surface plasmon resonance (SPR) sensor during last decade. The paper also focuses on the structure of Kretschmann configuration, the sensing principle of SPR, its characteristic parameters, application in various fields, and some important recent works related to SPR sensors have also been discussed, based on the present and future scope of this field. The present paper provides a platform for researchers to work in the field of 2D nanomaterial-based SPR sensors.


2021 ◽  
Vol 11 (7) ◽  
pp. 2963
Author(s):  
Nur Alia Sheh Omar ◽  
Yap Wing Fen ◽  
Irmawati Ramli ◽  
Umi Zulaikha Mohd Azmi ◽  
Hazwani Suhaila Hashim ◽  
...  

A novel vanadium–cellulose composite thin film-based on angular interrogation surface plasmon resonance (SPR) sensor for ppb-level detection of Ni(II) ion was developed. Experimental results show that the sensor has a linear response to the Ni(II) ion concentrations in the range of 2–50 ppb with a determination coefficient (R2) of 0.9910. This SPR sensor can attain a maximum sensitivity (0.068° ppb−1), binding affinity constant (1.819 × 106 M−1), detection accuracy (0.3034 degree−1), and signal-to-noise-ratio (0.0276) for Ni(II) ion detection. The optical properties of thin-film targeting Ni(II) ions in different concentrations were obtained by fitting the SPR reflectance curves using the WinSpall program. All in all, the proposed Au/MPA/V–CNCs–CTA thin-film-based surface plasmon resonance sensor exhibits better sensing performance than the previous film-based sensor and demonstrates a wide and promising technology candidate for environmental monitoring applications in the future.


2015 ◽  
Vol 145 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Marie-France Martin-Eauclaire ◽  
Géraldine Ferracci ◽  
Frank Bosmans ◽  
Pierre E. Bougis

Animal toxins that inhibit voltage-gated sodium (Nav) channel fast inactivation can do so through an interaction with the S3b–S4 helix-turn-helix region, or paddle motif, located in the domain IV voltage sensor. Here, we used surface plasmon resonance (SPR), an optical approach that uses polarized light to measure the refractive index near a sensor surface to which a molecule of interest is attached, to analyze interactions between the isolated domain IV paddle and Nav channel–selective α-scorpion toxins. Our SPR analyses showed that the domain IV paddle can be removed from the Nav channel and immobilized on sensor chips, and suggest that the isolated motif remains susceptible to animal toxins that target the domain IV voltage sensor. As such, our results uncover the inherent pharmacological sensitivities of the isolated domain IV paddle motif, which may be exploited to develop a label-free SPR approach for discovering ligands that target this region.


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