scholarly journals Use of Propensity Score Matching to Compare Short Outcomes from Transoral and External Surgical Approaches in Patients with Deep-Lobe Parotid Pleomorphic Adenomas

2021 ◽  
Vol 28 (4) ◽  
pp. 3115-3123
Author(s):  
Yue Fan ◽  
Shuguang Li ◽  
Shuting Yu ◽  
Xiaoli Zhu ◽  
Xiaohua Shi ◽  
...  
Keyword(s):  
Propensity Score ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Propensity Score Matching ◽  
Transoral Approach ◽  
External Approach ◽  
Deep Lobe ◽  
Hospitalization Time ◽  
Pleomorphic Adenomas ◽  
Approach Group

To compare the outcomes of patients who had deep-lobe parotid gland pleomorphic adenomas (PAs) that extended into the parapharyngeal space after surgical treatment, using a transoral approach or an external approach. One hundred and twelve eligible patients, with deep-lobe parotid gland PAs, were enrolled in this retrospective study. The surgical outcomes were compared for patients who received a transoral approach and an external approach, using 1:1 propensity score matching (PSM). The outcome measures were recurrence rate, facial nerve deficit, Frey’s syndrome, and hospitalization time. The median follow-up time was 4.8 years. After PSM, the transoral approach and external approach groups had no statistically significant difference in recurrence (10.3% vs. 3.4%; p = 0.201). The transoral approach group had no facial nerve deficit, but 5 of 29 patients (17.2%) in the external approach group had transient facial nerve paralysis (p = 0.052). The external approach group had a longer hospitalization time than the transoral approach group (5 vs. 4 days, p = 0.0017). The use of a transoral surgical approach to treat patients with deep-lobe parotid gland PAs led to low recurrence, shorter hospitalization times, and good functional and cosmetic outcomes.

Pleomorphic adenomas of the parotid gland: superficial parotidectomy or limited excision?

1988 ◽  
Vol 102 (7) ◽  
pp. 603-605 ◽  
Author(s):  
C. Wennmo ◽  
O. Spandow ◽  
P. Emgård ◽  
B. Krouthén
Keyword(s):  
Retrospective Study ◽  
Side Effects ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Superficial Parotidectomy ◽  
Operative Results ◽  
Gustatory Sweating ◽  
Pleomorphic Adenomas ◽  
Parotid Tumours

AbstractIn this retrospective study of parotid tumours. 57 patients with pleomorphic adenomas were treated with superficial parotidectomy and 33 patients with limited excision. The follow-up period has been 4–14 years. When the operation was superficial parotidectomy, recurrences occurred in 8.7 per cent compared to 6 per cent in cases of limited excision. Side-effects such as permanent weakness of the facial nerve or postoperative gustatory sweating were also more common when superficial parotidectomy was performed. The post-operative results observed suggest that limited excision under magnification is more favourable than superficial parotidectomy in the treatment of pleomorphic adenomas.

scholarly journals Transoral Excision of a Large Accessory Parotid Gland Tumor

2021 ◽  
pp. 014556132110362
Author(s):  
Rohith S. Voora ◽  
Joshua Stramiello ◽  
Emily Funk ◽  
Joseph Califano
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
Surgical Excision ◽  
Transoral Approach ◽  
Malignant Neoplasms ◽  
Gland Tumor ◽  
Parotid Gland Tumor ◽  
Facial Nerves ◽  
Endoscopic Assistance ◽  
Accessory Parotid Gland

Accessory parotid gland (APG) tumors account for 1% to 7% of all parotid gland neoplasms but are more likely to be malignant than main parotid gland tumors. Management of APG neoplasms entails surgical excision. Four primary approaches to resection have been described in the literature with varying facial nerve outcomes. We report a case of a 4-cm APG pleomorphic adenoma utilizing a transoral approach for excision without postoperative facial nerve injury. A transoral approach is known to mitigate patients’ cosmetic concerns; however, prior reports utilized endoscopic assistance on patients with smaller tumors. We conclude that large APG tumors can be excised through a transoral approach without undue risk to the distal facial nerves, though this transoral approach ultimately may not be appropriate for malignant neoplasms or difficult dissections.

Deep lobe parotid lipoma: a case report

1995 ◽  
Vol 109 (8) ◽  
pp. 772-773 ◽  
Author(s):  
Graeme M. Weiner ◽  
A. L. Pahor
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Facial Nerve ◽  
The Body ◽  
Common Occurrence ◽  
Superficial Parotidectomy ◽  
Deep Lobe ◽  
Simple Enucleation ◽  
The Common

AbstractWe present a patient with a lipoma of the deep lobe of the parotid gland. Despite the common occurrence of this tumour in other regions of the body, we believe that this is only the second report in the literature of a lipoma in this location. We believe that these tumours are easily dealt with by simple enucleation, and that superficial parotidectomy should be reserved for tumours deep to the facial nerve.

Oncocytic differentiation in salivary gland tumours

1995 ◽  
Vol 109 (6) ◽  
pp. 569-571 ◽  
Author(s):  
Jorge A. Ferreiro ◽  
Nickolaos Stylopoulos
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Mucoepidermoid Carcinoma ◽  
Facial Nerve Paralysis ◽  
Major Salivary Gland ◽  
Superficial Parotidectomy ◽  
Nerve Paralysis ◽  
Salivary Gland Tumours ◽  
Pleomorphic Adenomas

AbstractAn oncocytic mucoepidermoid carcinoma and an oncocytic pleomorphic adenoma occurred in a 47-year-old male and a 75-year-old female, respectively. Both presented as asymptomatic parotid gland masses without evidence of facial nerve paralysis and were treated by superficial parotidectomy. There has been no evidence of recurrence or metastasis. Oncocytic change is rare in major salivary gland mucoepidermoid carcinoma with only two previously reported cases. Marked oncocytic transformation of pleomorphic adenomas can cause their confusion with oncocytomas. Recognition of oncocytic differentiation in various salivary gland tumours is important to avoid misclassification of these lesions.

Infantile (desmoid-type) fibromatosis of the parotid gland

1997 ◽  
Vol 111 (7) ◽  
pp. 669-670 ◽  
Author(s):  
Ramesh Chandran Ramanathan ◽  
J. Meirion Thomas
Keyword(s):  
Local Recurrence ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Clinical Features ◽  
Surgical Excision ◽  
High Rate ◽  
Cytological Evidence ◽  
Deep Lobe ◽  
Complete Surgical Excision ◽  
Infancy And Childhood

AbstractInfantile fibromatosis, one of the fibrous tumours of infancy and childhood, is a fibroproliferative lesion characterized by aggressive local invasion without any tendency to metastasize, the absence of cytological evidence of malignancy and a high rate of local recurrence when incompletely excised. We report a case of infantile (desmoid-type) fibomatosis in a seven-year-old girl arising from the deep lobe of the parotid gland that was treated by complete surgical excision with preservation of the facial nerve. The clinical features, pathology and treatment are briefly discussed.

scholarly journals Excision of tumors in the parapharyngeal space using an endoscopically assisted transoral approach: a case series and literature review

2018 ◽  
Vol 47 (3) ◽  
pp. 1103-1113 ◽  
Author(s):  
Zhe Chen ◽  
Ya-Lian Chen ◽  
Qi Yu ◽  
Shui-Hong Zhou ◽  
Yang-Yang Bao ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Parotid Gland ◽  
Internal Carotid ◽  
Parapharyngeal Space ◽  
Jugular Vein ◽  
Minor Salivary Gland ◽  
Transoral Approach ◽  
Pathological Examination ◽  
Pleomorphic Adenomas

Objective Magnetic resonance imaging (MRI) provides important information regarding tumors in the parapharyngeal space (PPS), revealing their origin, whether they are benign or malignant, and their relationships with surrounding structures. Methods Twelve tumors in the PPS were completely excised using an endoscopically assisted transoral approach (EATA). The MRI features were analyzed. Results Ten pleomorphic adenomas confirmed on postoperative pathological examination had the parotid pedicle sign. A fat space between the tumor and parotid gland may distinguish such a tumor from a tumor arising from a minor salivary gland in the prestyloid space and a tumor arising from the deep lobe of the parotid gland. Both the jugular vein and carotid artery were displaced posteriorly in all 10 cases of pleomorphic adenomas. The principal features of the two schwannomas confirmed on postoperative pathological examination were separation of the internal carotid artery and internal jugular vein and anteromedial displacement of the internal carotid artery, suggesting that the tumors originated in the poststyloid space. In this review, 95 tumors were excised by the EATA in the English-language literature. Conclusions MRI renders differential diagnosis possible. PPS tumors may be completely excised via an EATA guided by tumor features evident on preoperative MRI.

scholarly journals Efficacy and Outcomes of Lianhuaqingwen Capsule for Coronavirus Disease 2019: A Retrospective Propensity Score Matching Analysis

2020 ◽  
Author(s):  
zhiyong liu ◽  
Yongsheng Du ◽  
Jiankun Liu ◽  
Xiaolong Wei ◽  
Feiyang Zheng ◽  
...  
Keyword(s):  
Treatment Group ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Controlled Trial ◽  
Large Population ◽  
Antiviral Agents ◽  
Clinical Effects ◽  
Propensity Score Matching Analysis ◽  
Usual Treatment ◽  
Hospitalization Time

Abstract Background: Coronavirus disease 2019 (COVID-19) has outbroken in Wuhan, China, in December, 2019, and became a global pandemic.No effective antiviral agents were approved for COVID-19. In this study, we aim to evaluate the efficacy and outcomes of Lianhuaqingwen (LH) capsulein patients with COVID-19.Methods:In this retrospective cohort study, we included 147 hospitalized patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)infection between February 4th and April 15th, 2020, in Wuhan Huoshen shan hospital. Patients were grouped as usual treatment alone or combination with LH capsules. Propensity score matching analysis were performed between two groups. Primary outcomes were mortality and duration of hospitalization time. Secondary outcomes included the recovery rate of chest radiological manifestations and abnormal laboratory examinations.Results: In two groups, 40 pairs patients were matched for analysis. The baseline information and clinical characteristics were comparable. 73 (91.25%) of all 80 patients were older than 50 years old. All patients in LH treatment group and 38 (95%) in usual treatment group were surviving respectively (P = 0.494). The hospitalization time of patients in LH treatment group was significantly shorter than usual treatment group (17.85±6.612vs.20.72±5.01 days, P = 0.032). After treatment, the rate of lung lesions detected by chest computerized tomography (CT) was lower in LH treatment group (30% vs. 55.0%, P = 0.024).Conclusion: LH capsules were associated with the improved clinical effects, and might be recommended in the treatment practices of COVID-19 patients. Moreover, further evaluation of LH capsules in large population randomized controlled trial is needed.

scholarly journals Therapeutic Experience of 189 Patients with Warthin's Tumor of the Parotid Gland

2018 ◽  
Vol 01 (01) ◽  
pp. e23-e27
Author(s):  
Tsuyoshi Jinnin ◽  
Masaaki Higashino ◽  
Shuji Nishikawa ◽  
Tetsuya Terada ◽  
Ryo Kawata
Keyword(s):  
Blood Loss ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Operative Time ◽  
Lower Pole ◽  
Warthin’S Tumor ◽  
Operative Blood Loss ◽  
Deep Lobe ◽  
Warthin's Tumor ◽  
Nerve Dysfunction

AbstractWe investigated the clinical characteristics and preoperative diagnosis rate of Warthin's tumor (WT) of the parotid gland. The subjects were 189 patients who underwent surgery at the Department of Otolaryngology, Head and Neck Surgery in Osaka Medical College between September 1999 and April 2017. We compared the date of the189 patients with 466 cases of pleomorphic adenoma (PA) of the parotid gland seen during the same period. Among the 189 patients with WT, there were 163 males and 26 females, with a median age of 62 years. The sites of origin of the tumors in the parotid gland were distributed as follows: superficial lobe, 64 cases; deep lobe, 14 cases; and lower pole, 111 cases. The median maximum diameter of the tumor was 30 mm. The median operative time and the median operative blood loss were 120 minutes and 20 mL, respectively. The diagnosis had been made accurately prior to the surgery in 72% of the patients, by the fine needle aspiration cytology. Postoperative facial nerve dysfunction occurred in 39 cases (20.6%); however, it was transient in all cases. The transient facial nerve dysfunction recovered within 2 months in 50% of all cases, within 6 months in 90%, and within 1 year in 100% of cases. The features that were especially frequently encountered in the cases with postoperative facial dysfunction were origin of the tumor in the deep lobe of the parotid and large size of the tumor; furthermore, these cases also required a longer operative time. As compared with PA, WT occurred more often in male patients. WTs occurred more often in the lower pole and they were larger in size. The operative blood loss was greater. There were no significant differences with regards to the incidence of postoperative facial nerve dysfunction and the operative time.

Besondere Förderung von Kern- kompetenzen an Spezialgymnasien?

2010 ◽  
Vol 24 (1) ◽  
pp. 5-22 ◽  
Author(s):  
Jürgen Baumert ◽  
Michael Becker ◽  
Marko Neumann ◽  
Roumiana Nikolova
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching

Der vorliegende Beitrag geht der Frage nach, ob Schülerinnen und Schüler, die nach der vierten Klasse in Berlin in ein grundständiges Gymnasium wechseln, in Abhängigkeit vom Profil des besuchten Gymnasiums im Vergleich zu Grundschülern mit vergleichbaren Lernvoraussetzungen unterschiedliche Lernzuwächse im Leseverständnis, in Mathematik und Englisch erreichen. Auf der Datengrundlage der ELEMENT-Studie wurde die Leistungsentwicklung von Schülerinnen und Schülern an grundständigen Gymnasien (N = 1758) und Grundschulen (N = 3169) während der 5. und 6. Jahrgangsstufe mithilfe von Propensity Score Matching-Analysen (PSM) modelliert. Nach Kontrolle von leistungsrelevanten Unterschieden zwischen den Schülergruppen am Ende der 4. Jahrgangsstufe zeigten sich für das Leseverständnis am Ende der 6. Klasse keine statistisch signifikanten Unterschiede. Für die Mathematikleistung ließen sich Unterschiede lediglich zugunsten eines grundständigen Gymnasiums, das zum Untersuchungszeitpunkt noch kein spezifisches Profil entwickelt hatte, nachweisen. In der Domäne Englisch, in der die curricularen Unterschiede zwischen den Schulzweigen stärker akzentuiert sind, wurden positive Ergebnisse im Vergleich zu den Grundschulen für die so genannten Schnellläuferzüge, die englisch-bilingualen Klassen und das grundständige Gymnasium ohne spezifisches Profil ermittelt. Die Lernstände am Ende der 6. Klasse in den altsprachlichen Gymnasien fielen dagegen im Vergleich zu den Grundschulen geringer aus. Die Befunde widersprechen der Annahme, dass mit dem frühen Übergang auf ein grundständiges Gymnasium automatisch eine besondere Förderung der Lesefähigkeit und des mathematischen Verständnisses besonders leistungsfähiger Schülerinnen und Schüler erreicht werde. Die Ergebnisse zu den Englischleistungen weisen hingegen darauf hin, dass Unterschiede in der Leistungsentwicklung auftreten können, sofern die Aufteilung auf Schulen mit unterschiedlichen Bildungsprogrammen mit curricularen Unterschieden im Unterricht einhergeht. Methodische und inhaltliche Implikationen der Befunde und Grenzen ihrer Generalisierbarkeit werden diskutiert.

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