Six-Minute Walk Distance in Breast Cancer Survivors—A Systematic Review with Meta-Analysis

The six-minute walk test (6MWT) is a widely used test for the indirect measurement of cardiorespiratory fitness in various cancer populations. Although the 6MWT is a simple test, there are no normative values for breast cancer survivors (BCS) or comparisons of results with healthy counterparts. A systematic review with a meta-analysis was carried out, which included studies from 2007 to 2020. Ninety-one studies were found, 21 of which were included in the quantitative synthesis. Among them were 9 randomized controlled trials (RCT), 8 prospective cohort studies and 4 cross-sectional studies. A total of 1084 BCS were included. Our results revealed that healthy subjects (n = 878) covered a significantly greater distance than BCS during the 6MWT (589.9 m vs. 477.4 m, p < 0.001), and the results of the meta-regression analysis showed that the 6MWD was predicted by the participants’ BMI (p < 0.001), but not by their age (p = 0.070). After adjustment for BMI, the healthy subjects also covered greater distances than the BCS (103 m; p < 0.001). The normative values of 6MWT were presented for BCS. Besides, 6MWT distances distinguish between their healthy counterparts, therefore, the 6MWT distance is a relevant parameter for the assessment and monitoring of cardiorespiratory fitness in medical and exercise interventions for BCS.

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145P The potential benefits of internet-based cognitive behavioural therapy for improving psychosocial aspects, sexual functioning, and treatment-induced menopausal symptoms among breast cancer survivors: Systematic review and meta-analysis

Annals of Oncology ◽

10.1016/j.annonc.2021.03.159 ◽

2021 ◽

Vol 32 ◽

pp. S83

Author(s):

B.P. Putra ◽

F.N. Putra

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Cancer Survivors ◽

Cognitive Behavioural Therapy ◽

Sexual Functioning ◽

Breast Cancer Survivors ◽

Meta Analysis ◽

Behavioural Therapy ◽

Cognitive Behavioural ◽

Potential Benefits

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Updated systematic review of exercise studies in breast cancer survivors: attention to the principles of exercise training

British Journal of Sports Medicine ◽

10.1136/bjsports-2017-098389 ◽

2017 ◽

Vol 53 (8) ◽

pp. 504-512 ◽

Cited By ~ 31

Author(s):

Sarah E Neil-Sztramko ◽

Kerri M Winters-Stone ◽

Kelcey A Bland ◽

Kristin L Campbell

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Exercise Training ◽

Cancer Survivors ◽

Randomised Controlled Trials ◽

Breast Cancer Survivors ◽

Exercise Prescription ◽

Controlled Trials ◽

Exercise Interventions ◽

Randomised Controlled

ObjectivesTo update our previous evaluation of the exercise interventions used in randomised controlled trials of breast cancer survivors in relation to (1) the application of the principles of exercise training in the exercise prescription; (2) the reporting of the components of the exercise prescription; and (3) the reporting of adherence of participants to the prescribed interventions.DesignSystematic review.Data sourcesThe OVID Medline, Embase, CINAHL and SPORTDiscus electronic databases were searched from January 2010 to January 2017.Eligibility criteriaRandomised controlled trials of at least 4 weeks of aerobic and/or resistance exercise in women diagnosed with breast cancer, reporting on physical fitness or body composition outcomes.ResultsSpecificity was appropriately applied by 84%, progression by 29%, overload by 38% and initial values by 67% of newly identified studies. Reversibility was reported by 3% anddiminishing returns by 22% of newly identified studies. No studies reported all components of the exercise prescription in the methods, or adherence to the prescribed intervention in the results. Reporting of reversibility has increased from 2010, but no other improvements in reporting were noted from the previous review.Summary/ConclusionNo studies of exercise in women with breast cancer attended to all principles of exercise training, or reported all components of the exercise prescription in the methods, or adherence to the prescription in the results. Full reporting of the exercise prescribed and completed is essential for study replication in research and translating research findings into the community, and should be prioritised in future trials.

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