scholarly journals Dissipation Behavior, Residue, and Risk Assessment of Benziothiazolinone in Apples

2021 ◽  
Vol 18 (9) ◽  
pp. 4478
Author(s):  
Yida Chai ◽  
Rong Liu ◽  
Wei He ◽  
Fuliu Xu ◽  
Zenglong Chen ◽  
...  
Keyword(s):  
High Performance ◽  
Daily Intake ◽  
Agricultural Practices ◽  
Degradation Behavior ◽  
Acceptable Daily Intake ◽  
Risk Quotient ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass ◽  
Final Residue

Benziothiazolinone is the first independently developed fungicide in China. It has been used to effectively control fungal diseases in a variety of fruits, vegetables, and crops. In this study, the degradation behavior and final residue of benziothiazolinone in apples is discussed, and the dietary risk to consumers was evaluated. High-performance liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to determine benziothiazolinone residues in apple samples from eight different regions of China. The average recovery of benziothiazolinone in apples was 85.5–100.2%, and the relative standard deviation (RSD) was 0.8–14.9%. The limits of the method of quantification of benziothiazolinone in apples was 0.01 mg/kg. Under good agricultural practices (GAP) conditions, the final residues of benziothiazolinone in apples were below 0.01 mg/kg, lower than the maximum residual limit (MRL) of China. Although the degradation half-lives of benziothiazolinone were 23.9 d–33.0 d, the risk quotient (RQ) of benziothiazolinone was 15.5% by calculating the national estimated daily intake and comparing it with the acceptable daily intake. These results suggested that under GAP conditions, the intake of benziothiazolinone from apples exhibits an acceptably low health risk on consumers.

Determination of Diflubenzuron Residues in Vegetables by UPLC-MS/MS

2014 ◽  
Vol 852 ◽  
pp. 266-269
Author(s):  
Xiao Fang Wang ◽  
Chun Liang Yang ◽  
Mao Fang Huang ◽  
Ming Yue Wang ◽  
Yu Bing Zha ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
High Performance ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass

The conditions for detecting residues of diflubenzuron in vegetables by ultra high performance liquid chromatography tandem mass spectrometry were studied. The target was extracted with acetonitrile for 2 min with a homogenizer. The extaction was purifide by a conditioned Florisil SPE cartridge, and then was detected by ultra high-performance liquid chromatography with tandem mass spectrometry. The average recovery was in the range from 87.8 %- 99.2 % at spike levels of 0.1, 1.0 and 10 mg/kg in vegetables, and relative standard deviations was in the range of 4.2 %-8.9 %. The proposed method is fast, simple, sensitive and accurate.

A Sensitive Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry Method Based on Derivatization with 1-Nitro-2-Naphthaldehyde for Determination of Alkylhydrazines in Surface water

2021 ◽  
Author(s):  
Jin-Ah Oh ◽  
Ho-Sang Shin ◽  
Hyun-Hee Lim
Keyword(s):  
Mass Spectrometry ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Surface Water ◽  
Tandem Mass Spectrometry ◽  
High Performance ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass

Abstract Background Alkylhydrazines are widely used in the industrial fields. An analysis of alkylhydrazines in surface water is need because these chemicals are likely to be discharged into wastewater and enter aquatic environments. Objective An ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method was developed to determine the levels of five alkylhydrazines (N,N-dimethylhydrazine, ethylhydrazine, 1-isopropylhydrazine, phenylhydrazine and 1-methyl-1-phenylhydrazine) in surface water. Methods This method is based on the derivatization of alkylhydrazines with 1-nitro-2-naphthaldehyde (NNA) in water. A derivatization reagent dosage of 0.5 mg of NNA, a pH of 2, and a reaction time of 30 min at 40 °C were determined to be the optimal conditions for UHPLC–MS/MS detection. The derivatives were injected into the LC system without additional extraction or purification steps. Results The proposed method was used under optimized conditions to detect alkylhydrazines in surface water, with the limit of quantification found to be 0.01–0.03 μg/L. The accuracy ranged from 91.0 to 106.0%, and the precision, expressed as the relative standard deviation, was less than 10%. Of the five alkylhydrazines, only N,N-dimethyl hydrazine was detected in the real samples at a concentration range of 0.010 to 0.041 μg/L. Conclusion The developed method can be used to confirm the presence of alkylhydrazine residues in surface water and represents an important tool for evaluating the fate of alkylhydrazines in surface water. Highlights This method to determine alkylhydrazine in surface water was developed simply and rapidly after derivatization reaction without an extraction or clean-up step in UHPLC-MS/MS.

scholarly journals Determination of Methomyl Residues in Bohe by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS)

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Yao Zheng ◽  
Addotey Tracy Naa Adoley ◽  
Benkhelifa Fateh ◽  
Wei Wu ◽  
Gengdong Hu ◽  
...  
Keyword(s):  
Daily Intake ◽  
Residue Level ◽  
Time Interval ◽  
Tandem Mass ◽  
Acceptable Daily Intake ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Ultrahigh Performance Liquid Chromatography ◽  
Sensitive Method

The aim of this work is to investigate the presence of methomyl pesticide residue and the rate of disappearance in mint cultivated in the aquaponics system based on the application of UPLC-MS to establish a safety time interval before crop harvesting. Results showed that an effective and sensitive method based on UPLC-MS has been used for the determination of methomyl pesticide residues in mint. The initial residue level was much higher in roots (79.52 μg/kg), and it can be decreased to 16.73 (after 15 days) μg/kg and 3.31 (20 days) μg/kg, while the least was detected on the mix leaves and stems (44.54 μg/kg), and it can be decreased to 15.35 (after 20 days). In our case, we suggest that a safety interval in the range of 15–20 days should be allowed after the detection of methomyl in water, and the concentration of methomyl was lower than the acceptable daily intake (ADI) of the China Food and Drug Administration (CFDA) (20 μg/kg).

Determination of Phenoxy Acid Herbicides in Cereals Using High-Performance Liquid Chromatography–Tandem Mass Spectrometry

2019 ◽  
Vol 82 (7) ◽  
pp. 1160-1165 ◽  
Author(s):  
TAO GUO ◽  
XIAOLI WANG ◽  
HAIFENG WANG ◽  
YUFEN HU ◽  
SHIYONG ZHANG ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acetic Acid ◽  
High Performance ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass ◽  
Phenoxy Acid Herbicides ◽  
Acid Herbicides

ABSTRACTAn effective method for determination of multiple residues of phenoxy acid herbicides in cereals was developed. A QuEChERS (quick, easy, cheap, effective, rugged, and safe) technique coupled with high-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) was optimized for the analysis of phenoxy acid herbicides in rice, corn, and wheat. The limits of detection in the experiment were 0.0500 μg/kg for 4-(2,4-dichlorophenoxy)acetic acid, (4-chloro-2-methylphenoxy)acetic acid, (2,4,5-trichlorophenoxy)acetic acid, and 2-(2,4-dichlorophenoxy)propionic acid and 0.300 μg/kg for 4-(2,4-dichlorophenoxy)butyric acid and 3,6-dichloro-2-methoxybenzoic acid. The relative standard deviation of intraday and interday precision for the six phenoxy acid herbicides was less than 6.61%, and accuracy was 96.3 to 107%. Extraction recovery for phenoxy acid herbicides was 73.8 to 115%, with relative standard deviations of less than 12.1% at three spiking levels (1.00, 4.00, and 20.0 μg/kg). These results indicate that QuEChERS sample preparation with HPLC-MS/MS analysis is a rapid, reliable, highly sensitive, and specific tool for the determination of phenoxy acid herbicide residues in cereals.HIGHLIGHTS

scholarly journals Determination of Methylene Blue and Its Metabolite Residues in Aquatic Products by High-Performance Liquid Chromatography–Tandem Mass Spectrometry

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4975
Author(s):  
Xuan Zhang ◽  
Yunhua Hui ◽  
Changling Fang ◽  
Yuan Wang ◽  
Feng Han ◽  
...  
Keyword(s):  
Methylene Blue ◽  
High Performance ◽  
Correlation Coefficients ◽  
Limit Of Quantification ◽  
Aquatic Products ◽  
Azure B ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass

A sensitive and reliable method was developed to determine methylene blue (MB) and its metabolite residues, including azure A (AZA), azure B (AZB), and azure C (AZC) in aquatic products by HPLC–MS/MS. The samples were extracted by acetonitrile and cleaned up by alumina-neutral (ALN) cartridges. The analytes were separated on a Sunfire C18 column (150 mm × 2.1 mm, 5 µm). The method was validated according to the European criteria of Commission Decision 2002/657/CE. Good linearity between 1–500 µg/L was obtained with correlation coefficients (R2) greater than 0.99. The limit of quantification (LOQ) was 1.0 µg/kg. The average recoveries at three levels of each compound (1, 5, and 10 µg/kg) were demonstrated to be in the range of 71.8–97.5%, with relative standard deviations (RSDs) from 1.05% to 8.63%. This method was suitable for the detection of methylene blue and its metabolite residues in aquatic products.

scholarly journals Dissipation of Emamectin Benzoate Residues in Rice and Rice-Growing Environments

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 483 ◽  
Author(s):  
Ligang Deng ◽  
Lu Chen ◽  
Shuai Guan ◽  
Junhua Liu ◽  
Jingyun Liang ◽  
...  
Keyword(s):  
High Performance ◽  
Rice Hull ◽  
Tandem Mass ◽  
Emamectin Benzoate ◽  
Rice Plants ◽  
Testing Method ◽  
Chromatography Tandem Mass Spectrometry ◽  
Relative Standard ◽  
Liquid Chromatography Tandem Mass ◽  
Average Recovery Rate

The experiment developed the ultra-high-performance liquid chromatography–tandem mass spectrometry (UPLC/MS/MS) method for testing emamectin benzoate, and studied the metabolism of emamectin benzoate in rice plants and rice-growing environments via application of this testing method. The dissipation curve of emamectin benzoate standard substance was good at 0.5–200 μg L−1, and its correlation coefficient was greater than 0.99. In the concentration range of 0.1–50 μg kg−1, the average recovery rate of plants, soil, and field water was 82 %–102 %, and relative standard deviation (RSD) was between 0.3 % and 15.9 %. Half-lives in rice plants and soil were 0.8–2.8 days and 1.9–3.8 days, respectively, and emamectin benzoate was not detected in rice or rice hull. The experiment showed that emamectin benzoate is harmless to human health at the concentration recommended by the manufacturer.

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