scholarly journals The Isotopic Signature of Lead Emanations during the Fire at Notre Dame Cathedral in Paris, France

Author(s):  
Philippe Glorennec ◽  
Aurélia Azema ◽  
Séverine Durand ◽  
Sophie Ayrault ◽  
Barbara Le Bot

When Notre Dame de Paris cathedral caught fire on 15 April 2019, lead particles were deposited in its surroundings. Our objective was to determine whether the lead plume had a homogeneous isotopic signature (i.e., a set of homogenous isotopic ratios), and whether, if so, this was different from common sources. In January 2020, dust samples were collected from six areas inside the cathedral, downwind of the fire, as well as from eight roof debris fragments. These samples were mineralized and analyzed using ICP-MS. Their isotopic ratios (207Pb/206Pb and 206Pb/204Pb) were determined and then compared both to each other and to previous published ratios measured in home dusts and blood samples collected in France. The isotopic ratios of dust samples collected inside the cathedral were compatible with each other and with the roof fragments. These isotopic ratios are common and differ neither from those of many other dusts collected in France during the period 2008–2009, nor from those of blood samples collected from children in France during the same period. Moreover, the fire’s isotopic signature is close to the overall signature for Paris. Indeed, it would be difficult to attribute the fire at the cathedral to either lead poisoning or environmental contamination.

Author(s):  
M. Kulvik ◽  
J. Laakso ◽  
J. Vähätalo ◽  
R. Zilliacus
Keyword(s):  
Icp Ms ◽  

2020 ◽  
Vol 22 (5) ◽  
pp. 1224-1232 ◽  
Author(s):  
T. L. Tasker ◽  
N. R. Warner ◽  
W. D. Burgos

Elemental and isotopic ratios can be used to identify environmental contamination form the increasing development of the Utica/Point Pleasant Shale.


Author(s):  
Iman A Al-Saleh ◽  
Craig Fellows ◽  
Trevor Delves ◽  
Andrew Taylor

The concentrations of lead and the isotopic ratios of lead, 206Pb:207Pb, were measured by inductively coupled plasma-mass spectrometry in environmental specimens, cosmetics and traditional remedies. The ratios were compared with those found in blood samples of Saudi children who had increased concentrations of total blood lead. The isotopic ratios in the blood specimens (1·144±0·027) were not significantly different from those determined in cosmetics and remedies (1·152±0·031) and indicated that these were the likely sources of exposure rather than the lead contained in petrol which had an isotopic ratio of 1·207.


2016 ◽  
Vol 1 (4) ◽  
pp. 203-208 ◽  
Author(s):  
Martin Graversen ◽  
Peter B. Pedersen ◽  
Michael B. Mortensen

AbstractBackground:Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative technique for intraperitoneal drug delivery. This study investigates the efficacy of the occupational health safety measures taken to prevent exposition of healthcare workers to the toxic chemotherapy aerosol.Methods:Air samples were taken at the working place of the surgeon and of the anesthetist during 2 PIPAC procedures and analyzed for content of platinum by inductively coupled plasma mass spectrometry (ICP-MS). Airborne particles were quantified in real time. Biological monitoring was performed in two surgeons after 50 PIPAC by examining blood samples for possible traces of platinum. Analysis was performed by an independent company.Results:Safety measures included tightly closed abdomen, operating room (OR), ventilation meeting requirements of ISO norm 14644–1 class 5, closed aerosol waste system and remote control of PIPAC administration. No traces of platinum were found in the air of the OR (detection limit of 0.0001 mg/filter). No specific rise in particle concentration was detected in the air during the PIPAC procedure, patient closure and removal of the sterile drapes. Blood samples of the surgeons showed no traces of platinum.Conclusions:After implementation of adequate safety measures, no signs of environmental contamination or biological exposure of the surgeons were detected during PIPAC.


2017 ◽  
Vol 37 (2) ◽  
pp. 244-256 ◽  
Author(s):  
Zhian Bao ◽  
Chunlei Zong ◽  
Linru Fang ◽  
Honglin Yuan ◽  
Kaiyun Chen ◽  
...  

2012 ◽  
Vol 64 (5) ◽  
pp. 1325-1334
Author(s):  
R.P. Oliveira ◽  
C. Ducatti ◽  
A.S. Carrijo ◽  
A.C. Pezzato ◽  
J.C. Denadai ◽  
...  

The inclusion of poultry viscera meal (VM) in broiler diets to possibly replace it with strictly vegetable diet (VE) and vice-versa, using the technique of carbon and nitrogen stable isotopes in different tissues was traced. One hundred ninety-two one-day-old chicks that had been distributed randomly were used in twelve experimental treatments with four replications of four chicks each. The treatments consisted of vegetable diet (VG) for diets containing FV going after a certain age or the reverse, in which the birds began feeding VM on diet and then switched to VE diet. At 42 days of age, samples of pectoral muscle (Pectoralis major), keel and tibia were collected, with later determination of isotopic ratios (13C/12C and 15N/14N). The stable isotopes technique couldn't trace the use of VM in feeding broilers when this ingredient was part of broiler diets only in the first seven, 14 or 21 days of age. However, this technique can be applied to younger poultry that have been sampled before a possible change in diet, since they can have the isotopic signature of feeding stabilized around two weeks of age.


2016 ◽  
Vol 6 (11) ◽  
pp. 2-8 ◽  
Author(s):  
John A. Kaufman ◽  
Mary Jean Brown ◽  
Nasir T. Umar-Tsafe ◽  
Muhammad Bashir Adbullahi ◽  
Kabiru I. Getso ◽  
...  

Background. In March 2010, Medecins Sans Frontieres/Doctors Without Borders detected an outbreak of acute lead poisoning in Zamfara State, northwestern Nigeria, linked to low-technology gold ore processing. The outbreak killed more than 400 children ≤5 years of age in the first half of 2010 and has left more than 2,000 children with permanent disabilities. Objectives. The aims of this study were to estimate the statewide prevalence of children ≤5 years old with elevated blood lead levels (BLLs) in gold ore processing and non-ore-processing communities, and to identify factors associated with elevated blood lead levels in children. Methods. A representative, population-based study of ore processing and non-ore-processing villages was conducted throughout Zamfara in 2012. Blood samples from children, outdoor soil samples, indoor dust samples, and survey data on ore processing activities and other lead sources were collected from 383 children ≤5 years old in 383 family compounds across 56 villages. Results. 17.2% of compounds reported that at least one member had processed ore in the preceding 12 months (95% confidence intervals (CI): 9.7, 24.7). The prevalence of BLLs ≥10 μg/dL in children ≤5 years old was 38.2% (95% CI: 26.5, 51.4) in compounds with members who processed ore and 22.3% (95% CI: 17.8, 27.7) in compounds where no one processed ore. Ore processing activities were associated with higher lead concentrations in soil, dust, and blood samples. Other factors associated with elevated BLL were a child's age and sex, breastfeeding, drinking water from a piped tap, and exposure to eye cosmetics. Conclusions. Childhood lead poisoning is widespread in Zamfara State in both ore processing and non-ore-processing settings, although it is more prevalent in ore processing areas. Although most children's BLLs were below the recommended level for chelation therapy, environmental remediation and use of safer ore processing practices are needed to prevent further exposures.


2021 ◽  
Vol 12 (3) ◽  
pp. 033-044
Author(s):  
Trupti Patil ◽  
Asmita Wele ◽  
Sangram Patil

Background: Gold bhasma [Swarnabhasma] is a ancient Ayurvedic medicine used for rejuvenation and longevity. This is a preliminary attempt to study the bioavailability of this medicine. Objectives: It was aimed to estimate comparative bioavailability of gold bhasma up to five hours after oral dose with four different anupana. Materials and methods: In this in vivo study, 30 healthy human participants were allocated randomly into five groups having six individuals each. Gold bhasma in 30 mg dose was administered orally with four different anupana viz honey [2.5 gm], black pepper-ghee combination [250 mg and 2.5 gm respectively], lactose [250 mg], glucose [250 mg], and plain to participants in each group. Blood samples were collected at 0, 1, 3 and 5 hours after dose. Gold levels in blood were assessed by inductively coupled plasma mass spectrometry [ICP-MS]. Results: Gold levels in all blood samples were in traces. Average Cmax was 0.002333 microgram of gold per liter and Tmax was at 3 hours for honey anupana, showing maximum Cmax among all groups. Conclusions: Preliminary results indicate that bioavailability of gold from gold bhasma may be less than 0.01 % upto first five hours. Gold bhasma mixed with honey resulted in attainment of maximum Cmax. It is evident that accompanying media [anupana] play an important role in absorption of gold bhasma.


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