scholarly journals Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders

2021 ◽  
Vol 18 (13) ◽  
pp. 6689
Author(s):  
Lilian Calderón-Garcidueñas ◽  
Ravi Philip Rajkumar ◽  
Elijah W. Stommel ◽  
Randy Kulesza ◽  
Yusra Mansour ◽  
...  
Keyword(s):  
Online Survey ◽  
Amyloid Β ◽  
Alpha Synuclein ◽  
Amyloid Β Peptide ◽  
Hyperphosphorylated Tau ◽  
Post Traumatic Stress ◽  
Impact Of Event Scale ◽  
Sleep Behavior ◽  
Event Scale ◽  
The Impact

Quadruple aberrant hyperphosphorylated tau (p-τ), amyloid-β peptide, alpha-synuclein and TDP-43 brainstem and supratentorial pathology are documented in forensic ≤40y autopsies in Metropolitan Mexico City (MMC), and p-τ is the major aberrant protein. Post-traumatic stress disorder (PTSD) is associated with an elevated risk of subsequent dementia, and rapid eye movement sleep behavior disorder (RBD) is documented in PD, AD, Lewy body dementia and ALS. This study aimed to identify an association between PTSD and potential pRBD in Mexico. An anonymous online survey of 4502 urban college-educated adults, 29.3 ± 10.3 years; MMC, n = 1865; non-MMC, n = 2637, measured PTSD symptoms using the Impact of Event Scale–Revised (IES-R) and pRBD symptoms using the RBD Single-Question. Over 50% of the participants had IES-R scores ≥33 indicating probable PTSD. pRBD was identified in 22.6% of the participants across Mexico and 32.7% in MMC residents with PTSD. MMC subjects with PTSD had an OR 2.6218 [2.5348, 2.7117] of answering yes to the pRBD. PTSD and pRBD were more common in women. This study showed an association between PTSD and pRBD, strengthening the possibility of a connection with misfolded proteinopathies in young urbanites. We need to confirm the RBD diagnosis using an overnight polysomnogram. Mexican women are at high risk for stress and sleep disorders.

scholarly journals Psychological Impact of the COVID-19 Pandemic on Adults and Their Children in Italy

2021 ◽  
Vol 12 ◽  
Author(s):  
Chiara Davico ◽  
Ada Ghiggia ◽  
Daniele Marcotulli ◽  
Federica Ricci ◽  
Federico Amianto ◽  
...  
Keyword(s):  
High Risk ◽  
Sex Education ◽  
Traumatic Stress ◽  
Online Survey ◽  
Psychological Impact ◽  
Post Traumatic Stress ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Post Traumatic ◽  
The Impact

Aim: The coronavirus disease 2019 (COVID-19) pandemic has abruptly changed the life of millions as travel and social contacts have been severely restricted. We assessed the psychological impact of COVID-19 on adults and children, with special attention to health care workers (HCWs).Methods: A self-rated online survey, including the Impact of Event Scale-Revised (IES-R) for adults and the Children Revised Impact of Event Scale-Revised-13 items (CRIES-13) for their 8–18-year-old offspring, was conducted in Italy on March 20–26, 2020. Linear mixed-effects models were applied to the data, accounting for age, sex, education, and other demographic characteristics.Results: Data were available from 2,419 adults (78.4% females, mean age 38.1 ± SD 13.1 years; 15.7% HCW) and 786 children (50.1% male, mean age 12.3 ± 3.2 years). Median (IQR) IES-R score was 30.0 (21.0–40.0), corresponding to mild psychological impact, with 33.2% reporting severe psychological impact. IES-R was lower in HCWs (29.0) than non-HCWs (31.0), but HCWs directly involved in COVID-19 care had higher scores [33.0 (26.0–43.2)] than uninvolved HCWs [28.0 (19.0–36.0)]. Median CRIES-13 score was [21.0 (11.0–32.0)], with 30.9% of the children at high risk for post-traumatic stress disorder. Parent and child scores were correlated.Conclusions: Up to 30% of adult and children in the pandemic area are at high risk for post-traumatic stress disturbances. The risk is greater for HCWs directly involved in COVID-19 care and for their children.

Effects of Support Groups on Post Traumatic Stress Responses in Women Experiencing Stillbirth

2007 ◽  
Vol 55 (1) ◽  
pp. 71-90 ◽  
Author(s):  
Joanne Cacciatore
Keyword(s):  
Support Groups ◽  
Support Group ◽  
Stress Responses ◽  
Traumatic Stress ◽  
Post Traumatic Stress ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Quantitative Results ◽  
Post Traumatic ◽  
The Impact

This research study explores the effects of support groups on traumatic stress responses of women experiencing stillbirth. Women ( N = 47) responded to a mixed method questionnaire. Quantitative results utilizing the Impact of Event Scale Revised demonstrate that women who attend support group, when controlling for time, had fewer post traumatic stress symptoms than did the women who did not attend support group. Qualitative results elucidate the role of support groups in managing grief, suggesting that connectivity with other like women may be a useful strategy in reducing problematic psychological outcomes.

Early Psychological Reactions in a Group of Individuals with Pre-existing and Enduring Mental Health Difficulties Following a Major Coach Accident

1996 ◽  
Vol 169 (4) ◽  
pp. 430-433 ◽  
Author(s):  
Helen L. Chubb ◽  
Jonathan I. Bisson
Keyword(s):  
Mental Health ◽  
Depressive Disorders ◽  
Depression Scale ◽  
Chronic Schizophrenia ◽  
Post Traumatic Stress ◽  
Psychological Sequelae ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Mental Health Difficulties ◽  
The Impact

BackgroundThe impact of major trauma on individuals with pre-existing and enduring mental health difficulties is poorly understood.MethodTwenty individuals with pre-existing and enduring mental health difficulties were assessed with the Clinician Administered Post Traumatic Stress Disorder Scale, the 28-item version of the GHQ, the Hospital Anxiety and Depression Scale, and the Impact of Event Scale between four and eight weeks after their involvement in a major coach accident.ResultsTen (50%) individuals satisfied the full DSM–IV criteria for a diagnosis of PTSD. The questionnaire scores indicated a high level of psychological suffering among the group. On dividing the sample into those individuals with previous diagnoses of anxiety or depressive disorders and those with a previous diagnosis of chronic schizophrenia, the schizophrenia group displayed less marked psychological sequelae on all measures.ConclusionThere was a high incidence of early psychological sequelae among the group as a whole. Some diagnoses (e.g. depression and anxiety) may predispose to psychological sequelae while others (e.g. chronic schizophrenia) may not.

scholarly journals Impact of COVID-19 Pandemic on the Psychological Outcomes: Multiple Indicators and Multiple Causes (MIMIC) Modeling

2021 ◽  
Author(s):  
Musheer A. Aljaberi ◽  
Naser A. Alareqe ◽  
Mousa A. Qasem ◽  
Abdulsamad Alsalahi ◽  
Sarah Noman ◽  
...  
Keyword(s):  
Structural Equation ◽  
Online Survey ◽  
Psychological Impact ◽  
Psychological Outcomes ◽  
Post Traumatic Stress ◽  
Latent Factors ◽  
Event Scale ◽  
Multiple Indicators ◽  
The Impact ◽  
Multiple Causes

Abstract Background: Due to the limited research examining the psychological impact of coronavirus disease 2019 (COVID-19), our study aims to investigate the effect of the COVID-19 pandemic on psychological outcomes and assess the differences between participants with and without post-traumatic stress disorder (PTSD) on the psychological outcomes as latent factors and items. Methods: An online survey was conducted on 999 participants. The Impact of Event Scale-Revised (IES-R) assessed the psychological impact, while outcomes were measured by Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder (GAD-7), and Insomnia Severity Index (ISI). A series of Confirmatory Factor Analysis (CFA), structural equation model (SEM), Multiple Indicators and Multiple Causes (MIMIC), and Differential Item Functioning (DIF) were conducted. Results: The IES-R has significant effects on the psychological outcomes. Participants with PTSD have a higher impact on latent factors (depression, anxiety, and insomnia) than those without PTSD. Among participants, 36.5% experienced moderate to severe symptoms of depression, and 32.6% had mild depressive symptoms. For anxiety, 23.7% of respondents experienced moderate to severe anxiety symptoms, and 33.1% had mild symptoms of anxiety. For the ISI, 51.5% of participants experienced symptoms of insomnia. Conclusion: the IES-R for COVID-19 has a significant impact on depression, anxiety, and insomnia at the level of latent constructs and observed variables.

scholarly journals Impact of Event Scale-6 (IES-6) for U.S. Adults Who Experienced the COVID-19 Pandemic

2021 ◽  
Author(s):  
Jiin Jeong ◽  
Ah-Ram Kim ◽  
Claudia Hilton ◽  
Ickpyo Hong
Keyword(s):  
Rating Scale ◽  
Item Difficulty ◽  
Principal Component ◽  
The United States ◽  
Rapid Identification ◽  
Post Traumatic Stress ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Item Fit ◽  
The Impact

Abstract Background: Post-traumatic stress disorder (PTSD) is a mental illness caused by traumatic events, such as the COVID-19 pandemic. Accurate diagnosis of this disorder is critical to establish effective intervention approaches. The Impact of Event Scale-6 (IES-6) is widely used for PTSD screening, but there has been no research on its psychometric properties with individuals who experienced the COVID-19 pandemic.Methods: A random sample of 600 participants were randomly selected from a COVID-19 survey database (n = 6,391). Rasch analysis was conducted to examine item fit, rating scale structure, construct validity, differential item functioning (DIF), and precision of the IES-6. Results: The principal component analysis of Rasch residuals (54.1% of the raw variance explained) and the average of residual correlations (average r = .19) supported the unidimensionality structure in the IES-6. The rating scale was suitable, and the item difficulty hierarchy was logical. The item fit and the DIF contrast were acceptable, except for item 5. The IES-6’s person reliability was .76, which was also an acceptable level.Conclusions: This study showed that the IES-6 has acceptable item-level psychometrics for screening PTSD in adults in the United States for individuals who have experienced the COVID-19 pandemic. The findings suggested that the IES-6 would be useful for the rapid identification of PTSD and allow clinicians to quickly provide interventions for people with the disorder and their families.

scholarly journals Coping Strategies and Psychopathological Responses Among Medical and Non-medical Professionals – a Cross-Sectional Online Survey

2021 ◽  
Vol 12 ◽  
Author(s):  
Marta Ciułkowicz ◽  
Julian Maciaszek ◽  
Błażej Misiak ◽  
Anna Pałȩga ◽  
Joanna Rymaszewska ◽  
...  
Keyword(s):  
Coping Strategies ◽  
Online Survey ◽  
General Health Questionnaire ◽  
Well Being ◽  
Medical Professionals ◽  
Post Traumatic Stress ◽  
Cross Sectional ◽  
Event Scale ◽  
Medical Career ◽  
The Impact

Background: The SARS-CoV-2 pandemic was announced on March 11th, 2020, due to a surge of newly confirmed cases that significantly impacted populations worldwide, both directly and indirectly. Based on past epidemics research, the mental health implications of introduced restrictions should be expected and adequately addressed irrespective of the practiced profession.Objective: The study aimed to explore psychopathological responses, including post-traumatic stress disorder (PTSD), concerning coping strategy clusters during the COVID-19 pandemic among medical and non-medical workers.Methods: A cross-sectional web survey of the general population of internet users was performed from March 16th to April 26th, 2020, in Poland during the first peak of COVID-19 cases. A sample of 1,831 professionally active respondents, 64.0% of which pursuing a medical career, filled out General Health Questionnaire-28 (GHQ-28), The Impact of Event Scale-Revised (IES-R), and MiniCOPE, along with the socio-demographic questionnaire exploring personal as well as the work-related possibility of direct exposure to contagion and availability of proper protection, contact with the infected without accurate protective measures as well as the adequacy of workers when compared settings.Results: Individuals labeled with specific clusters had significantly different psychopathological manifestations. Irrespective of performed job maladaptive cluster was associated with significantly higher GHQ-28 and IES-R scores on total subscales and all subscales compared to those representing the non-specific and adaptive cluster. Similar findings were observed concerning the frequency of the GHQ-28 positive score. Moreover, the non-specific cluster was associated with significantly higher GHQ-28 total scores among medical professionals. However, GHQ-28 positive scores were significantly more frequent in medical workers using adaptive clusters when compared to non-specific. Such relations were not observed in the non-medical group.IES-R total and subscales' scores did not significantly vary within medical and non-medical groups when adaptive and non-specific clusters were compared. Pursuing a non-medical career was found to be a determinant of lower scores, while female sex was observed to be determinant of higher scores in both GHQ-28 and IES-R scales.Conclusions: Positive screening for psychopathological and PTSD symptoms was expected regardless of the analyzed groups' coping strategies. Given the dramatically developing situation of the COVID-19 pandemic, support initiatives grounded in research evidence may be essential for maintaining the mental well-being and resilience of both the medical and non-medical workforce.

scholarly journals A cross-sectional survey of psychological distress in a Mexican sample during the second phase of the COVID-19 pandemic

2020 ◽  
Author(s):  
Aldebarán Toledo-Fernández ◽  
Diana Betancourt-Ocampo ◽  
Héctor Romo-Parra ◽  
Ernesto Reyes-Zamorano ◽  
Alejandro González-González
Keyword(s):  
Psychological Distress ◽  
Online Survey ◽  
Second Phase ◽  
Cross Sectional Survey ◽  
Baseline Measure ◽  
Cross Sectional ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Related Stress ◽  
The Impact

The objectives of this study were to describe severity of psychological distress (event-related stress, anxiety, and depression) during the second stage of COVID-19 pandemic in Mexico, and to explore associations between the indicators of psychological distress, sociodemographic characteristics and specific concerns about COVID-19. This report serves as a baseline measure of a longitudinal project to evaluate progression of psychological distress across stages of the COVID-19 pandemic in Mexico. An online survey was conducted in the State of Mexico from April 8th -18th, 2020, in a sample of men and women who are beneficiaries of a welfare institution in the region. Variables were measured with the Impact of Event Scale-6, Patient Health Questionnaire-9, General Anxiety Disoder-7, and a questionnaire of concerns about COVID-19. A total of 5974 participants were analyzed. Moderate levels of psychological distress (with 23.6% of participants meeting significant event-related stress, but mild levels of depression and anxiety) were found, as well as high values in all concerns about COVID-19, especially regarding financial disruption, worsening of local security and concern of a family member becoming infected. These concerns associated mild-to-moderately with the indicators of psychological distress. Higher values of event-related distress were found in women, individuals with higher educational attainment and those with any current high-risk medical diagnosis, though the effect sizes were mild. Though psychological distress and concerns about COVID-19 have reached significant levels during the pandemic in Mexico, overall, they have not yet reached dysfunctional levels.

scholarly journals EMDR intervention after a disaster: The Morandi Bridge collapse

2019 ◽  
Vol 15 (3) ◽  
Author(s):  
Isabel Fernandez ◽  
Chiara Callerame
Keyword(s):  
Traumatic Event ◽  
Poor Quality ◽  
World Health ◽  
Traumatic Experience ◽  
Post Traumatic Stress ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Pre Treatment ◽  
Health Organization ◽  
The Impact

Survivors involved in natural or man-made disasters can develop a range of psychological problems including Post-Traumatic Stress Disorder (PTSD), depression, other forms of psychological distress, and a poor quality of life. Therefore, the principal focus of early psychological interventions, according to World Health Organization, is to provide a rapid and effective therapeutical approach like EMDR therapy. The EMDR approach enables the assimilation and integration of the various aspects of a traumatic experience at a somatic, sensorial, cognitive, behavioral and emotional level. In this article will be presented data of 47 patients collected after the partial collapse of Morandi bridge, in Genoa, in August 2018. Survivors were treated applying the Recent Traumatic Episode Protocol (R-TEP); in order to evaluate the effect of the traumatic event and to monitor the intervention outcome, the Impact of Event Scale- Revised (IES-R) was administered to each person pre and after EMDR treatment. Results show that regardless the number of sessions and the time elapsed after the disaster in which they were performed, EMDR significantly reduced participants’ IES-R scores from pre-treatment to posttreatment. Clinical implications and limits of the study will be discussed.

Post-traumatic stress symptoms following sniper attacks: Effects of television viewing and identification with victims

2018 ◽  
Vol 13 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Holly B. Herberman Mash, PhD ◽  
Carol S. Fullerton, PhD ◽  
Robert J. Ursano, MD
Keyword(s):  
Posttraumatic Stress ◽  
Traumatic Stress ◽  
Online Survey ◽  
Peritraumatic Dissociation ◽  
Post Traumatic Stress ◽  
Tv Viewing ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
Stress Symptoms ◽  
Post Traumatic

Objective: A series of sniper attacks in the Washington, DC, area left 10 people dead and three wounded. The authors examined the relationship of sniper-related television (TV) viewing, identification with victims, and peritraumatic dissociation to posttraumatic stress symptoms.Methods: Participants were 1,238 DC residents (ages 18-90, M = 41.7; 51 percent female; 68 percent White) who completed an online survey including items assessing identification, amount of TV, peritraumatic dissociation, and post-traumatic stress symptoms. Identification was measured by assessing to what extent participants identified victims as similar to themselves, a friend, or a family member. Peritraumatic dissociation and post-traumatic stress symptoms were assessed with the Peritraumatic Dissociative Experiences Questionnaire and Impact of Event Scale-Revised. Relationships of TV viewing, identification, and peritraumatic dissociation to post-traumatic stress symptoms were examined by univariable and multivariable regressions and variable interactions.Results: Female gender and higher levels of TV viewing, identification, and peritraumatic dissociation were each related to greater post-traumatic stress symptoms. After adjusting for gender and the predictor variables, higher TV viewing was associated with posttraumatic stress symptoms (B = 0.72, p 0.01, ΔR2 = 0.05). Participants with greater identification (B = 0.85, p 0.001, ΔR2 = 0.08) and peritraumatic dissociation (B = 1.58, p 0.001, ΔR2 = 0.39) reported more post-traumatic stress symptoms. Among those with both high (B = 1.19, p 0.001) and low TV viewing, identification was associated with post-traumatic stress symptoms. Among those reporting low TV viewing, this association was greater for those who experienced more peritraumatic dissociation (B = −0.09, p 0.001).Conclusions: Trauma-related TV viewing, which may stimulate identification and peritraumatic dissociation, is an important consideration in understanding development of post-traumatic stress symptoms.

Comparative Analysis of the Japanese Version of the Revised Impact of Event Scale: A Study of Firefighters

2008 ◽  
Vol 23 (S1) ◽  
pp. s20-s26 ◽  
Author(s):  
Satoko Mitani
Keyword(s):  
Social Support ◽  
High Risk ◽  
Traumatic Event ◽  
Japanese Version ◽  
Epidemiological Studies ◽  
Post Traumatic Stress ◽  
Job Stressors ◽  
Impact Of Event Scale ◽  
Event Scale ◽  
The Impact

AbstractIntroduction:The Impact of Event Scale Revised (IES-R) has been used in various epidemiological studies to assess the prevalence of post-traumatic stress disorder (PTSD). Previous studies using the IES-R Japanese version to assess the mental health of firefighters were based on the premise that firefighters had experienced a traumatic event(s) as a matter of course. However, use of the IES-R-J does not indicate whether or not a traumatic event was experienced. The purpose of this study is to clarify the differences between: (1) IES-R-J high and low score groups; and (2) those who report symptoms similar to those of PTSD with and without having been being exposed to a traumatic event.Methods:Questionnaire packets distributed to all 157 workers in a Japanese fire station included the IES-R, the Japan Brief Job Stress Questionnaire, a questionnaire regarding traumatic event experiences, and demographic questions. Participants who scored ≥25 points on the IES-R-J scale were defined as the PTSD high risk (HR) group; those with scores <25 points as the PTSD low risk (LR) group.Results:One hundred thirty-one of the 157 subjects (83.4%) responded to the questionnaire; three were excluded from the analysis because of missing data. The mean total IES-R-J score was 14.9 ±15.2. Twenty-eight subjects scored in the PTSD HR group (≥25); 100 scored in the LR group (<25). A total of 54 (42.2%) participants had experienced a traumatic event; 57.8% had not. In the HR group, 14 subjects had experienced a traumatic event and 14 had not. Participants who had experienced a traumatic event reported a higher incidence of intrusion/re-experience symptoms than did those who had not experienced a traumatic event. The level of social support significantly affected the risk for PTSD.Firefighters who scored ≥25 on the IES-R-J and, thus, considered to be at high risk for the development of PTSD, were less confident about their health, experienced more job stressors and had less social support than did those whose IES-R-J scores were <25. Having experienced a traumatic event was reported by only 42% of all the participants and by only 50% of those in the high risk PTSD group.Conclusions:Although the IES-R is an easily-administered tool useful in epidemiological studies evaluating psychological stress, it is recommended that the questionnaire be amended to include a question regarding the existence of a threatened experience or event and to analyze the data using positive and negative predictive value methodology.

Sign in / Sign up

Export Citation Format

Share Document