scholarly journals Organizing and Analyzing Data from the SHARE Study with an Application to Age and Sex Differences in Depressive Symptoms

2021 ◽  
Vol 18 (18) ◽  
pp. 9684
Author(s):  
Lara Lusa ◽  
Marianne Huebner
Keyword(s):  
Sex Differences ◽  
Data Analysis ◽  
Data Management ◽  
Longitudinal Design ◽  
Complex Structure ◽  
Data Set ◽  
Adequate Treatment ◽  
Health Lifestyle ◽  
Share Study ◽  
Share Data

The SHARE study contains health, lifestyle, and socioeconomic data from individuals ages 50 and older in European countries collected over several waves. Leveraging these data for research purposes can be daunting due to the complex structure of the longitudinal design. The two aims of our study are (1) to develop a framework and R code for data management of the SHARE data to prepare for data analysis, and (2) to demonstrate how to apply the framework to a specific research question, where the aim is to model the presence of clinically significant depression assessed by the 12-item Europe depression scale. The result is a framework that substantially reduces the time to initiate research studies using SHARE data, facilitating the data extraction, data preparation and initial data analysis, with reproducible R code. Further, we illustrate the extensive work required to prepare an analysis-ready data set to ensure the validity of the modeling results. This underlines the importance of carefully considering and recording data management decisions that have to be built into the research process. The results about sex differences in the probability of depression are consistent with previous literature. Our findings about age-associated changes can be opportunities for adequate treatment interventions.

Integrative Data Analysis from a Unifying Research Synthesis Perspective

2018 ◽  
Author(s):  
Eun-Young Mun ◽  
Anne E. Ray
Keyword(s):  
Data Analysis ◽  
Large Scale ◽  
Research Synthesis ◽  
Alcohol Intervention ◽  
Data Set ◽  
Integrative Data Analysis ◽  
Level Data ◽  
Model Complex ◽  
Wide Range ◽  
Individual Participant

Integrative data analysis (IDA) is a promising new approach in psychological research and has been well received in the field of alcohol research. This chapter provides a larger unifying research synthesis framework for IDA. Major advantages of IDA of individual participant-level data include better and more flexible ways to examine subgroups, model complex relationships, deal with methodological and clinical heterogeneity, and examine infrequently occurring behaviors. However, between-study heterogeneity in measures, designs, and samples and systematic study-level missing data are significant barriers to IDA and, more broadly, to large-scale research synthesis. Based on the authors’ experience working on the Project INTEGRATE data set, which combined individual participant-level data from 24 independent college brief alcohol intervention studies, it is also recognized that IDA investigations require a wide range of expertise and considerable resources and that some minimum standards for reporting IDA studies may be needed to improve transparency and quality of evidence.

Reproducibility and efficiency in handling complex neurophysiological data

Neuroforum ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Michael Denker ◽  
Sonja Grün ◽  
Thomas Wachtler ◽  
Hansjörg Scherberger
Keyword(s):  
Best Practices ◽  
Data Management ◽  
Data Integrity ◽  
Behavioral Neuroscience ◽  
Data Set ◽  
Data Publication ◽  
Electrophysiological Data ◽  
Data Formats ◽  
Neurophysiological Data ◽  
Community Effort

Abstract Preparing a neurophysiological data set with the aim of sharing and publishing is hard. Many of the available tools and services to provide a smooth workflow for data publication are still in their maturing stages and not well integrated. Also, best practices and concrete examples of how to create a rigorous and complete package of an electrophysiology experiment are still lacking. Given the heterogeneity of the field, such unifying guidelines and processes can only be formulated together as a community effort. One of the goals of the NFDI-Neuro consortium initiative is to build such a community for systems and behavioral neuroscience. NFDI-Neuro aims to address the needs of the community to make data management easier and to tackle these challenges in collaboration with various international initiatives (e.g., INCF, EBRAINS). This will give scientists the opportunity to spend more time analyzing the wealth of electrophysiological data they leverage, rather than dealing with data formats and data integrity.

scholarly journals Bayesian Network Structure and Predictability of Autistic Traits

2020 ◽  
pp. 003329412097815
Author(s):  
Giovanni Briganti ◽  
Donald R. Williams ◽  
Joris Mulder ◽  
Paul Linkowski
Keyword(s):  
Sex Differences ◽  
Network Analysis ◽  
Bayesian Network ◽  
Network Structure ◽  
Network Connectivity ◽  
Autistic Traits ◽  
Data Set ◽  
Conditional Dependence ◽  
Bayesian Network Structure ◽  
Male Subjects

The aim of this work is to explore the construct of autistic traits through the lens of network analysis with recently introduced Bayesian methods. A conditional dependence network structure was estimated from a data set composed of 649 university students that completed an autistic traits questionnaire. The connectedness of the network is also explored, as well as sex differences among female and male subjects in regard to network connectivity. The strongest connections in the network are found between items that measure similar autistic traits. Traits related to social skills are the most interconnected items in the network. Sex differences are found between female and male subjects. The Bayesian network analysis offers new insight on the connectivity of autistic traits as well as confirms several findings in the autism literature.

SEMIPARAMETRIC CLUSTERING METHOD FOR MICROARRAY DATA ANALYSIS

2008 ◽  
Vol 06 (02) ◽  
pp. 261-282 ◽  
Author(s):  
AO YUAN ◽  
WENQING HE
Keyword(s):  
Data Analysis ◽  
Microarray Data ◽  
Mixture Distribution ◽  
Information Criterion ◽  
Optimal Number ◽  
Microarray Data Analysis ◽  
Parametric Methods ◽  
Clustering Methods ◽  
Microarray Gene Expression ◽  
Data Set

Clustering is a major tool for microarray gene expression data analysis. The existing clustering methods fall mainly into two categories: parametric and nonparametric. The parametric methods generally assume a mixture of parametric subdistributions. When the mixture distribution approximately fits the true data generating mechanism, the parametric methods perform well, but not so when there is nonnegligible deviation between them. On the other hand, the nonparametric methods, which usually do not make distributional assumptions, are robust but pay the price for efficiency loss. In an attempt to utilize the known mixture form to increase efficiency, and to free assumptions about the unknown subdistributions to enhance robustness, we propose a semiparametric method for clustering. The proposed approach possesses the form of parametric mixture, with no assumptions to the subdistributions. The subdistributions are estimated nonparametrically, with constraints just being imposed on the modes. An expectation-maximization (EM) algorithm along with a classification step is invoked to cluster the data, and a modified Bayesian information criterion (BIC) is employed to guide the determination of the optimal number of clusters. Simulation studies are conducted to assess the performance and the robustness of the proposed method. The results show that the proposed method yields reasonable partition of the data. As an illustration, the proposed method is applied to a real microarray data set to cluster genes.

Twitter users exhibited coping behaviours during the COVID-19 lockdown: an analysis of tweets using mixed methods

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ruchi Mittal ◽  
Wasim Ahmed ◽  
Amit Mittal ◽  
Ishan Aggarwal
Keyword(s):  
Data Analysis ◽  
The Body ◽  
Data Set ◽  
Content Type ◽  
Twitter Data ◽  
Long Run ◽  
The World ◽  
Twitter Users ◽  
The Government ◽  
Using Data

Purpose Using data from Twitter, the purpose of this paper is to assess the coping behaviour and reactions of social media users in response to the initial days of the COVID-19-related lockdown in different parts of the world. Design/methodology/approach This study follows the quasi-inductive approach which allows the development of pre-categories from other theories before the sampling and coding processes begin, for use in those processes. Data was extracted using relevant keywords from Twitter, and a sample was drawn from the Twitter data set to ensure the data is more manageable from a qualitative research standpoint and that meaningful interpretations can be drawn from the data analysis results. The data analysis is discussed in two parts: extraction and classification of data from Twitter using automated sentiment analysis; and qualitative data analysis of a smaller Twitter data sample. Findings This study found that during the lockdown the majority of users on Twitter shared positive opinions towards the lockdown. The results also found that people are keeping themselves engaged and entertained. Governments around the world have also gained support from Twitter users. This is despite the hardships being faced by citizens. The authors also found a number of users expressing negative sentiments. The results also found that several users on Twitter were fence-sitters and their opinions and emotions could swing either way depending on how the pandemic progresses and what action is taken by governments around the world. Research limitations/implications The authors add to the body of literature that has examined Twitter discussions around H1N1 using in-depth qualitative methods and conspiracy theories around COVID-19. In the long run, the government can help citizens develop routines that help the community adapt to a new dangerous environment – this has very effectively been shown in the context of wildfires in the context of disaster management. In the context of this research, the dominance of the positive themes within tweets is promising for policymakers and governments around the world. However, sentiments may wish to be monitored going forward as large-spikes in negative sentiment may highlight lockdown-fatigue. Social implications The psychology of humans during a pandemic can have a profound impact on how COVID-19 shapes up, and this shall also include how people behave with other people and with the larger environment. Lockdowns are the opposite of what societies strive to achieve, i.e. socializing. Originality/value This study is based on original Twitter data collected during the initial days of the COVID-19-induced lockdown. The topic of “lockdowns” and the “COVID-19” pandemic have not been studied together thus far. This study is highly topical.

Integrated Production Data Analysis and Water Injection Optimization in A Giant Carbonate Field

2021 ◽  
Author(s):  
Adel Mehrabadi ◽  
Gabriele Urbani ◽  
Simona Renna ◽  
Lucia Rossi ◽  
Italo Luciani ◽  
...  
Keyword(s):  
Data Analysis ◽  
Water Injection ◽  
Water Flooding ◽  
Integrated Analysis ◽  
Production Data ◽  
Data Set ◽  
Proper Actions ◽  
Injection Scheme ◽  
Vertical Heterogeneity ◽  
Current Water

Abstract In case of giant brown fields, a proper water injection management can result in a very complex process, due to the quality and quantity of data to be analysed. Main issue is the understanding of the injected water preferential paths, especially in carbonate environment characterized by strong vertical and areal heterogeneities (karst). A structured workflow is presented to analyze and integrate a massive data set, in order to understand and optimize the water injection scheme. An extensive Production Data Analysis (PDA) has been performed, based on the integration of available geological data (including NMR and Cased Hole Logs), production (allocated rates, Well Tests, PLT), pressure (SBHP, RFT, MDT, ESP) and salinity data. The applied workflow led to build a Fluid Path Conceptual Model (FPCM), an easy but powerful tool to visualize the complex dynamic connections between injectors-producers and aquifer influence areas. Several diagnostic plots were performed to support and validate the main outcomes. On this basis, proper actions were implemented to optimize the current water injection scheme. The workflow was applied on a carbonate giant brown field characterized by three different reservoir members, hydraulically communicating at original conditions, characterized by high vertical heterogeneity and permeability contrast. Moreover, dissolution phenomena, localized in the uppermost reservoir section, led to important permeability enhancement through a wide network of connected vugs, acting as water preferential communication pathways. The geological analysis played a key role to investigate the reservoir water flooding mechanism in dynamic conditions. The water rising mechanism was identified to be driven by the high permeability contrast, hence characterized by lateral independent movements in the different reservoir members. The integrated analysis identified room for optimization of the current water injection strategy. In particular, key factor was the analysis and optimization at block scale, intended as areal and vertical sub-units, as identified by the PDA and visualized through the FPCM. Actions were suggested, including injection rates optimization and the definition of new injections points. A detailed surveillance plan was finally implemented to monitor the effects of the proposed actions on the field performances, proving the robustness of the methodology. Eni workflow for water injection analysis and optimization was previously successfully tested only in sandstone reservoirs. This paper shows the robustness of the methodology also in carbonate environment, where water encroachment is strongly driven by karst network. The result is a clear understanding of the main dynamics in the reservoir, which allows to better tune any action aimed to optimize water injection and increase the value of mature assets.

Big Data management and data analysis: Applied solutions in view of the spheres of the modern economy

2021 ◽  
pp. 281-306
Author(s):  
Larisa A. Ilyina ◽  
Ekaterina V. Lyubimova ◽  
Darya A. Prosvirina ◽  
Anton N. Sunteev
Keyword(s):  
Big Data ◽  
Data Analysis ◽  
Data Management ◽  
Modern Economy
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